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Select item 114967501.

Spt5 orchestrates cryptic transcript suppression and transcriptional directionality

Haejin An, Hyeokjun Yang, Daeyoup Lee

Commun Biol. 2024; 7: 1370. Published online 2024 Oct 22. doi: 10.1038/s42003-024-07014-7

PMCID:: PMC11496750

Article PDF–4.2M

Select item 96002192.

The Role of S. cerevisiae Sub1/PC4 in Transcription Elongation Depends on the C-Terminal Region and Is Independent of the ssDNA Binding Domain

Alejandro Collin, Araceli González-Jiménez, María del Carmen González-Jiménez, Manuel J. Alfonso, Olga Calvo

Cells. 2022 Oct; 11(20): 3320. Published online 2022 Oct 21. doi: 10.3390/cells11203320

PMCID:: PMC9600219

Article PDF–2.7M

Select item 68426143.

The capping enzyme facilitates promoter escape and assembly of a follow-on preinitiation complex for reinitiation

Rina Fujiwara, Nivedita Damodaren, Jeremy E. Wilusz, Kenji Murakami

Proc Natl Acad Sci U S A. 2019 Nov 5; 116(45): 22573–22582. Published online 2019 Oct 7. doi: 10.1073/pnas.1905449116

PMCID:: PMC6842614

Article PDF–1.7M

Select item 54997664.

The elongation factor Spt4/5 regulates RNA polymerase II transcription through the nucleosome

John B. Crickard, Jaehyoun Lee, Tae-Hee Lee, Joseph C. Reese

Nucleic Acids Res. 2017 Jun 20; 45(11): 6362–6374. Published online 2017 Apr 3. doi: 10.1093/nar/gkx220

PMCID:: PMC5499766

Article PDF–1.9M

Select item 53947985.

Spt5 plays vital roles in the control of sense and antisense transcription elongation

Ameet Shetty, Scott P. Kallgren, Carina Demel, Kerstin C. Maier, Dan Spatt, Burak H. Alver, Patrick Cramer, Peter J. Park, Fred Winston

Mol Cell. Author manuscript; available in PMC 2018 Apr 6.

Published in final edited form as: Mol Cell. 2017 Apr 6; 66(1): 77–88.e5. Published online 2017 Mar 30. doi: 10.1016/j.molcel.2017.02.023

PMCID:: PMC5394798

Article PDF–2.2M

Select item 53382396.

The yeast transcription elongation factor Spt4/5 is a sequence‐specific RNA binding protein

Amanda J. Blythe, Berra Yazar‐Klosinski, Michael W. Webster, Eefei Chen, Marylène Vandevenne, Katerina Bendak, Joel P. Mackay, Grant A. Hartzog, Alice Vrielink

Protein Sci. 2016 Sep; 25(9): 1710–1721. Published online 2016 Jul 15. doi: 10.1002/pro.2976

PMCID:: PMC5338239

Article PDF–4.4M

Select item 45617237.

Structures and Functions of the Multiple KOW Domains of Transcription Elongation Factor Spt5

Peter A. Meyer, Sheng Li, Mincheng Zhang, Kentaro Yamada, Yuichiro Takagi, Grant A. Hartzog, Jianhua Fu

Mol Cell Biol. 2015 Oct; 35(19): 3354–3369. Prepublished online 2015 Jul 27. Published online 2015 Sep 4. doi: 10.1128/MCB.00520-15

PMCID:: PMC4561723

Article PDF–4.8M

Select item 27439168.

Core Structure of the yeast Spt4-Spt5 Complex: A Conserved Module for Regulation of Transcription Elongation

Min Guo, Fei Xu, Jena Yamada, Thea Egelhofer, Yongxiang Gao, Grant A. Hartzog, Maikun Teng, Liwen Niu

Structure. Author manuscript; available in PMC 2009 Nov 1.

Published in final edited form as: Structure. 2008 Nov 12; 16(11): 1649–1658. doi: 10.1016/j.str.2008.08.013

PMCID:: PMC2743916

Article PDF–1.1M

Select item 12145419.

Analysis of a Splice Array Experiment Elucidates Roles of Chromatin Elongation Factor Spt4–5 in Splicing

Yuanyuan Xiao, Yee H Yang, Todd A Burckin, Lily Shiue, Grant A Hartzog, Mark R Segal

PLoS Comput Biol. 2005 Sep; 1(4): e39. Published online 2005 Sep 16. doi: 10.1371/journal.pcbi.0010039

PMCID:: PMC1214541

Article PDF–627K

Select item 36013410.

SPT5, an essential gene important for normal transcription in Saccharomyces cerevisiae, encodes an acidic nuclear protein with a carboxy-terminal repeat.

M S Swanson, E A Malone, F Winston

Mol Cell Biol. 1991 Jun; 11(6): 3009–3019. doi: 10.1128/mcb.11.6.3009

Correction in:: Mol Cell Biol. 1991 Aug; 11(8): 4286.

PMCID:: PMC360134

Article PDF–2.5M

Select item 813681911.

Opposite roles of transcription elongation factors Spt4/5 and Elf1 in RNA polymerase II transcription through B-form versus non-B DNA structures

Jun Xu, Jenny Chong, Dong Wang

Nucleic Acids Res. 2021 May 21; 49(9): 4944–4953. Published online 2021 Apr 20. doi: 10.1093/nar/gkab240

PMCID:: PMC8136819

Article PDF–2.4M

Select item 787939012.

Acute stress drives global repression through two independent RNA polymerase II stalling events in Saccharomyces

Nitika Badjatia, Matthew J. Rossi, Alain R. Bataille, Chitvan Mittal, William K.M. Lai, B. Franklin Pugh

Cell Rep. Author manuscript; available in PMC 2021 Feb 12.

Published in final edited form as: Cell Rep. 2021 Jan 19; 34(3): 108640. doi: 10.1016/j.celrep.2020.108640

PMCID:: PMC7879390

Article PDF–2.5M

Select item 563892413.

Translesion synthesis DNA polymerase η exhibits a specific RNA extension activity and a transcription-associated function

Vamsi K. Gali, Eva Balint, Nataliia Serbyn, Orsolya Frittmann, Francoise Stutz, Ildiko Unk

Sci Rep. 2017; 7: 13055. Published online 2017 Oct 12. doi: 10.1038/s41598-017-12915-1

PMCID:: PMC5638924

Article PDF–2.5M

Select item 309969814.

The Transcription Elongation Factor Spt5 Influences Transcription by RNA Polymerase I Positively and Negatively

Susan J. Anderson, Martha L. Sikes, Yinfeng Zhang, Sarah L. French, Shilpa Salgia, Ann L. Beyer, Masayasu Nomura, David A. Schneider

J Biol Chem. 2011 May 27; 286(21): 18816–18824. Published online 2011 Apr 5. doi: 10.1074/jbc.M110.202101

PMCID:: PMC3099698

Article PDF–2.0M

Select item 120513915.

Spt4, Spt5 and Spt6 Interactions: Effects on Transcription and Viability in Saccharomyces Cerevisiae

M. S. Swanson, F. Winston

Genetics. 1992 Oct; 132(2): 325–336. doi: 10.1093/genetics/132.2.325

PMCID:: PMC1205139

Summary PDF–4.5M

Select item 20761916.

In Vivo Evidence that Defects in the Transcriptional Elongation Factors RPB2, TFIIS, and SPT5 Enhance Upstream Poly(A) Site Utilization

Yajun Cui, Clyde L. Denis

Mol Cell Biol. 2003 Nov; 23(21): 7887–7901. doi: 10.1128/MCB.23.21.7887-7901.2003

PMCID:: PMC207619

Article PDF–583K

Select item 914960317.

FACT is recruited to the +1 nucleosome of transcribed genes and spreads in a Chd1-dependent manner

Célia Jeronimo, Andrew Angel, Vu Q. Nguyen, Jee Min Kim, Christian Poitras, Elie Lambert, Pierre Collin, Jane Mellor, Carl Wu, François Robert

Mol Cell. Author manuscript; available in PMC 2022 Sep 2.

Published in final edited form as: Mol Cell. 2021 Sep 2; 81(17): 3542–3559.e11. Published online 2021 Aug 10. doi: 10.1016/j.molcel.2021.07.010

PMCID:: PMC9149603

Article PDF–3.0M

Select item 848992518.

Recruitment of Xrn1 to stress-induced genes allows efficient transcription by controlling RNA polymerase II backtracking

José García-Martínez, María E. Pérez-Martínez, José E. Pérez-Ortín, Paula Alepuz

RNA Biol. 2021; 18(10): 1458–1474. Published online 2020 Dec 15. doi: 10.1080/15476286.2020.1857521

PMCID:: PMC8489925

Article PDF–9.7M

Select item 776875519.

Dynamics of RNA polymerase II and elongation factor Spt4/5 recruitment during activator-dependent transcription

Grace A. Rosen, Inwha Baek, Larry J. Friedman, Yoo Jin Joo, Stephen Buratowski, Jeff Gelles

Proc Natl Acad Sci U S A. 2020 Dec 22; 117(51): 32348–32357. Published online 2020 Dec 8. doi: 10.1073/pnas.2011224117

PMCID:: PMC7768755

Article PDF–1.3M

Select item 749133020.

Prefoldin-like Bud27 influences the transcription of ribosomal components and ribosome biogenesis in Saccharomyces cerevisiae

Verónica Martínez-Fernández, Abel Cuevas-Bermúdez, Francisco Gutiérrez-Santiago, Ana I. Garrido-Godino, Olga Rodríguez-Galán, Antonio Jordán-Pla, Sergio Lois, Juan C. Triviño, Jesús de la Cruz, Francisco Navarro

RNA. 2020 Oct; 26(10): 1360–1379. doi: 10.1261/rna.075507.120