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Select item 103184521.

CYP4F2 is a human-specific determinant of circulating N-acyl amino acid levels

Julia T. Tanzo, Veronica L. Li, Amanda L. Wiggenhorn, Maria Dolores Moya-Garzon, Wei Wei, Xuchao Lyu, Wentao Dong, Usman A. Tahir, Zsu-Zsu Chen, Daniel E. Cruz, Shuliang Deng, Xu Shi, Shuning Zheng, Yan Guo, Mario Sims, Monther Abu-Remaileh, James G. Wilson, Robert E. Gerszten, Jonathan Z. Long, Mark D. Benson

J Biol Chem. 2023 Jun; 299(6): 104764. Published online 2023 Apr 28. doi: 10.1016/j.jbc.2023.104764

PMCID:: PMC10318452

Abstract Article PDF–2.6M

Select item 101706972.

Computational analysis of missense variant CYP4F2*3 (V433M) in association with human CYP4F2 dysfunction: a functional and structural impact

Mahvash Farajzadeh-Dehkordi, Ladan Mafakher, Fatemeh Samiee-Rad, Babak Rahmani

BMC Mol Cell Biol. 2023; 24: 17. Published online 2023 May 9. doi: 10.1186/s12860-023-00479-0

PMCID:: PMC10170697

Abstract Article PDF–2.2M

Select item 98362953.

Suggestive evidence of CYP4F2 gene polymorphisms with HAPE susceptibility in the Chinese Han population

Lining Si, Haiyuan Wang, Rong Wang, Lhachen Tsering, Qifu Long, Yahui Jiang, Yun Yi, Yanli Zhao

PLoS One. 2023; 18(1): e0280136. Published online 2023 Jan 12. doi: 10.1371/journal.pone.0280136

PMCID:: PMC9836295

Abstract Article PDF–1.1M

Select item 71612544.

The correlation between CYP4F2 variants and chronic obstructive pulmonary disease risk in Hainan Han population

Yipeng Ding, Yixiu Yang, Quanni Li, Qiong Feng, Dongchuan Xu, Cibing Wu, Jie Zhao, Xiaoli Zhou, Huan Niu, Ping He, Jianfang Liu, Hongxia Yao

Respir Res. 2020; 21: 86. Published online 2020 Apr 15. doi: 10.1186/s12931-020-01348-6

PMCID:: PMC7161254

Abstract Article PDF–641K

Select item 67375895.

Genetic variants in CYP4F2 were significantly correlated with susceptibility to ischemic stroke

Yuan Wu, Junjie Zhao, Yonglin Zhao, Tingqin Huang, Xudong Ma, Honggang Pang, Ming Zhang

BMC Med Genet. 2019; 20: 155. Published online 2019 Sep 11. doi: 10.1186/s12881-019-0888-6

PMCID:: PMC6737589

Abstract Article PDF–710K

Select item 65424616.

Effect of CYP4F2, VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single-Patient Data Meta-Analysis in More Than 15,000 Individuals

Elisa Danese, Sara Raimondi, Martina Montagnana, Angela Tagetti, Taimour Langaee, Paola Borgiani, Cinzia Ciccacci, Antonio J. Carcas, Alberto M. Borobia, Hoi Y. Tong, Cristina Dávila-Fajardo, Mariana Rodrigues Botton, Stephane Bourgeois, Panos Deloukas, Michael D. Caldwell, Jim K. Burmester, Richard L. Berg, Larisa H. Cavallari, Katarzyna Drozda, Min Huang, Li-Zi Zhao, Han-Jing Cen, Rocio Gonzalez-Conejero, Vanessa Roldan, Yusuke Nakamura, Taisei Mushiroda, Inna Y. Gong, Richard B. Kim, Keita Hirai, Kunihiko Itoh, Carlos Isaza, Leonardo Beltrán, Enrique Jiménez-Varo, Marisa Cañadas-Garre, Alice Giontella, Marianne K. Kringen, Kari Bente Foss Haug, Hye Sun Gwak, Kyung Eun Lee, Pietro Minuz, Ming Ta Michael Lee, Steven A. Lubitz, Stuart Scott, Cristina Mazzaccara, Lucia Sacchetti, Ece Genç, Mahmut Özer, Anil Pathare, Rajagopal Krishnamoorthy, Andras Paldi, Virginie Siguret, Marie-Anne Loriot, Vijay Kumar Kutala, Guilherme Suarez-Kurtz, Jamila Perini, Josh C. Denny, Andrea H. Ramirez, Balraj Mittal, Saurabh Singh Rathore, Hersh Sagreiya, Russ Altman, Mohamed Hossam A. Shahin, Sherief I. Khalifa, Nita A. Limdi, Charles Rivers, Aditi Shendre, Chrisly Dillon, Ivet M. Suriapranata, Hong-Hao Zhou, Sheng-Lan Tan, Vacis Tatarunas, Vaiva Lesauskaite, Yumao Zhang, Anke H. Maitland-van der Zee, Talitha I. Verhoef, Anthonius de Boer, Monica Taljaard, Carlo Federico Zambon, Vittorio Pengo, Jieying Eunice Zhang, Munir Pirmohamed, Julie A. Johnson, Cristiano Fava

Clin Pharmacol Ther. Author manuscript; available in PMC 2020 Jun 1.

Published in final edited form as: Clin Pharmacol Ther. 2019 Jun; 105(6): 1477–1491. Published online 2019 Feb 17. doi: 10.1002/cpt.1323

Correction in:: Clin Pharmacol Ther. 2024 Jul 22

PMCID:: PMC6542461

Abstract Article PDF–613K

Select item 58077557.

Cytochrome P450 family 4 subfamily F member 2 (CYP4F2) rs1558139, rs2108622 polymorphisms and susceptibility to several cardiovascular and cerebrovascular diseases

Tao Zhang, Kuiying Yu, Xuhua Li

BMC Cardiovasc Disord. 2018; 18: 29. Published online 2018 Feb 9. doi: 10.1186/s12872-018-0763-y

PMCID:: PMC5807755

Abstract Article PDF–1.0M

Select item 48520138.

Influence of the CYP4F2 polymorphism on the risk of hemorrhagic complications in coumarin-treated patients

Peng Chen, Ye-Qi Sun, Guo-Ping Yang, Rong Li, Jie Pan, Yu-Sheng Zhou

Saudi Med J. 2016 Apr; 37(4): 361–368. doi: 10.15537/smj.2016.4.14036

PMCID:: PMC4852013

Abstract Article PDF–769K

Select item 42610599.

PharmGKB summary: very important pharmacogene information for CYP4F2

Maria L. Alvarellos, Katrin Sangkuhl, Roxana Daneshjou, Michelle Whirl-Carrillo, Russ B. Altman, Teri E. Klein

Pharmacogenet Genomics. Author manuscript; available in PMC 2016 Jan 1.

Published in final edited form as: Pharmacogenet Genomics. 2015 Jan; 25(1): 41–47. doi: 10.1097/FPC.0000000000000100

PMCID:: PMC4261059

Article PDF–175K

Select item 406282410.

Vascular characterization of mice with endothelial expression of cytochrome P450 4F2

Jennifer Cheng, Matthew L. Edin, Samantha L. Hoopes, Hong Li, J. Alyce Bradbury, Joan P. Graves, Laura M. DeGraff, Fred B. Lih, Victor Garcia, Jafar Sadik B. Shaik, Kenneth B. Tomer, Gordon P. Flake, John R. Falck, Craig R. Lee, Samuel M. Poloyac, Michal L. Schwartzman, Darryl C. Zeldin

FASEB J. 2014 Jul; 28(7): 2915–2931. doi: 10.1096/fj.13-241927

PMCID:: PMC4062824

Abstract Article

Select item 405282511.

CYP4F2 genetic polymorphisms are associated with coronary heart disease in a Chinese population

Changqing Yu, Qingkai Yan, Chunjiang Fu, Weibin Shi, Hongyong Wang, Chunyu Zeng, Xukai Wang

Lipids Health Dis. 2014; 13: 83. Published online 2014 May 20. doi: 10.1186/1476-511X-13-83

PMCID:: PMC4052825

Abstract Article PDF–253K

Select item 373175512.

Impact of the CYP4F2 p.V433M Polymorphism on Coumarin Dose Requirement: Systematic Review and Meta-Analysis

E Danese, M Montagnana, JA Johnson, AE Rettie, CF Zambon, SA Lubitz, G Suarez-Kurtz, LH Cavallari, L Zhao, M Huang, Y Nakamura, T Mushiroda, MK Kringen, P Borgiani, C Ciccacci, NT Au, T Langaee, V Siguret, MA Loriot, H Sagreiya, RB Altman, MHA Shahin, SA Scott, SI Khalifa, B Chowbay, IM Suriapranata, M Teichert, BH Stricker, M Taljaard, MR Botton, JE Zhang, M Pirmohamed, X Zhang, JF Carlquist, BD Horne, MTM Lee, V Pengo, GC Guidi, P Minuz, C Fava

Clin Pharmacol Ther. Author manuscript; available in PMC 2013 Dec 1.

Published in final edited form as: Clin Pharmacol Ther. 2012 Dec; 92(6): 746–756. Published online 2012 Nov 7. doi: 10.1038/clpt.2012.184

PMCID:: PMC3731755

Abstract Article PDF–4.7M

Select item 348799513.

Correlation between single nucleotide polymorphisms in CYP4F2 and warfarin dosing in chinese valve replacement patients

Jie-Hui Li, Guo-Guo Ma, Shu-Qiang Zhu, Hao Yan, Yong-Bing Wu, Jian-Jun Xu

J Cardiothorac Surg. 2012; 7: 97. Published online 2012 Sep 27. doi: 10.1186/1749-8090-7-97

PMCID:: PMC3487995

Abstract Article PDF–796K

Select item 295587214.

Common Variants of Cytochrome P450 4F2 Exhibit Altered Vitamin E-ω-Hydroxylase Specific Activity

Sabrina A. Bardowell, David E. Stec, Robert S. Parker

J Nutr. 2010 Nov; 140(11): 1901–1906. Published online 2010 Sep 22. doi: 10.3945/jn.110.128579

PMCID:: PMC2955872

Abstract Article PDF–598K

Select item 272433315.

Factor-Analysis Methods for Higher-Performance Neural Prostheses

Gopal Santhanam, Byron M. Yu, Vikash Gilja, Stephen I. Ryu, Afsheen Afshar, Maneesh Sahani, Krishna V. Shenoy

J Neurophysiol. 2009 Aug; 102(2): 1315–1330. Published online 2009 Mar 18. doi: 10.1152/jn.00097.2009

PMCID:: PMC2724333

Abstract Article

Select item 268488316.

CYP4F2 Is a Vitamin K₁ Oxidase: An Explanation for Altered Warfarin Dose in Carriers of the V433M Variant

Matthew G. McDonald, Mark J. Rieder, Mariko Nakano, Clara K. Hsia, Allan E. Rettie

Mol Pharmacol. 2009 Jun; 75(6): 1337–1346. Published online 2009 Mar 18. doi: 10.1124/mol.109.054833

PMCID:: PMC2684883

Abstract Article PDF–321K

Select item 239096817.

Association of a Functional Cytochrome P450 4F2 Haplotype with Urinary 20-HETE and Hypertension

Hong Liu, Yanyan Zhao, Dong Nie, Jingpu Shi, Lingyu Fu, Yan Li, Dahai Yu, Jingyu Lu

J Am Soc Nephrol. 2008 Apr; 19(4): 714–721. doi: 10.1681/ASN.2007060713

PMCID:: PMC2390968

Abstract Article

Select item 228872118.

CYP4F2 genetic variant alters required warfarin dose

Michael D. Caldwell, Tarif Awad, Julie A. Johnson, Brian F. Gage, Mat Falkowski, Paul Gardina, Jason Hubbard, Yaron Turpaz, Taimour Y. Langaee, Charles Eby, Cristi R. King, Amy Brower, John R. Schmelzer, Ingrid Glurich, Humberto J. Vidaillet, Steven H. Yale, Kai Qi Zhang, Richard L. Berg, James K. Burmester

Blood. 2008 Apr 15; 111(8): 4106–4112. Prepublished online 2008 Feb 4. doi: 10.1182/blood-2007-11-122010

PMCID:: PMC2288721

Abstract Article

Select item 767500019.

A Genome-wide Association Study Discovers 46 Loci of the Human Metabolome in the Hispanic Community Health Study/Study of Latinos

Elena V. Feofanova, Han Chen, Yulin Dai, Peilin Jia, Megan L. Grove, Alanna C. Morrison, Qibin Qi, Martha Daviglus, Jianwen Cai, Kari E. North, Cathy C. Laurie, Robert C. Kaplan, Eric Boerwinkle, Bing Yu

Am J Hum Genet. 2020 Nov 5; 107(5): 849–863. Published online 2020 Oct 7. doi: 10.1016/j.ajhg.2020.09.003

PMCID:: PMC7675000

Abstract Article PDF–1.8M

Select item 739697720.

CYP4F2 and VKORC1 Polymorphisms Amplify the Risk of Carotid Plaque Formation

Stefan Cristian Vesa, Sonia Irina Vlaicu, Vitalie Vacaras, Sorin Crisan, Octavia Sabin, Sergiu Pasca, Adrian Pavel Trifa, Tamas Rusz-Fogarasi, Madalina Sava, Anca Dana Buzoianu

Genes (Basel) 2020 Jul; 11(7): 822. Published online 2020 Jul 20. doi: 10.3390/genes11070822

PMCID:: PMC7396977

Abstract Article PDF–671K

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