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Select item 101378801.

Understanding HAT1: A Comprehensive Review of Noncanonical Roles and Connection with Disease

Miguel A. Ortega, Diego De Leon-Oliva, Cielo Garcia-Montero, Oscar Fraile-Martinez, Diego Liviu Boaru, María del Val Toledo Lobo, Ignacio García-Tuñón, Mar Royuela, Natalio García-Honduvilla, Julia Bujan, Luis G. Guijarro, Melchor Alvarez-Mon, Miguel Ángel Alvarez-Mon

Genes (Basel) 2023 Apr; 14(4): 915. Published online 2023 Apr 14. doi: 10.3390/genes14040915

PMCID:: PMC10137880

Abstract Article PDF–1.1M

Select item 100929462.

HAT1: Landscape of Biological Function and Role in Cancer

Vincenza Capone, Laura Della Torre, Daniela Carannante, Mehrad Babaei, Lucia Altucci, Rosaria Benedetti, Vincenzo Carafa

Cells. 2023 Apr; 12(7): 1075. Published online 2023 Apr 2. doi: 10.3390/cells12071075

PMCID:: PMC10092946

Abstract Article PDF–1.6M

Select item 78574303.

Histone acetyltransferase 1 is a succinyltransferase for histones and non‐histones and promotes tumorigenesis

Guang Yang, Ying Yuan, Hongfeng Yuan, Jiapei Wang, Haolin Yun, Yu Geng, Man Zhao, Linhan Li, Yejing Weng, Zixian Liu, Jinyan Feng, Yanan Bu, Lei Liu, Bingnan Wang, Xiaodong Zhang

EMBO Rep. 2021 Feb 3; 22(2): e50967. Published online 2020 Dec 29. doi: 10.15252/embr.202050967

PMCID:: PMC7857430

Abstract Article PDF–4.1M

Select item 78409944.

Histone Acetyltransferase 1 Promotes Cell Proliferation and Induces Cisplatin Resistance in Hepatocellular Carcinoma

Xin Jin, Shenghua Tian, Pingping Li

Oncol Res. 2017; 25(6): 939–946. Published online 2017 Jul 5. doi: 10.3727/096504016X14809827856524

PMCID:: PMC7840994

Abstract Article PDF–10M

Select item 67078315.

HAT1 coordinates histone production and acetylation via H4 promoter binding

Joshua J. Gruber, Benjamin Geller, Andrew M. Lipchik, Justin Chen, Ameen A. Salahudeen, Ashwin N. Ram, James M. Ford, Calvin J. Kuo, Michael P. Snyder

Mol Cell. Author manuscript; available in PMC 2020 Aug 22.

Published in final edited form as: Mol Cell. 2019 Aug 22; 75(4): 711–724.e5. Published online 2019 Jul 2. doi: 10.1016/j.molcel.2019.05.034

PMCID:: PMC6707831

Abstract Article PDF–1.9M

Select item 41290016.

RNAi screening identifies HAT1 as a potential drug target in esophageal squamous cell carcinoma

Liang Xue, Jun Hou, Qun Wang, Liqing Yao, Songtao Xu, Di Ge

Int J Clin Exp Pathol. 2014; 7(7): 3898–3907. Published online 2014 Jun 15.

PMCID:: PMC4129001

Abstract Article PDF–1.2M

Select item 36899697.

Histone Acetyltransferase 1 Promotes Homologous Recombination in DNA Repair by Facilitating Histone Turnover

Xiaohan Yang, Lei Li, Jing Liang, Lei Shi, Jianguo Yang, Xia Yi, Di Zhang, Xiao Han, Na Yu, Yongfeng Shang

J Biol Chem. 2013 Jun 21; 288(25): 18271–18282. Published online 2013 May 7. doi: 10.1074/jbc.M113.473199

PMCID:: PMC3689969

Abstract Article PDF–1.4M

Select item 106171868.

Decreased HAT1 expression in granulosa cells disturbs oocyte meiosis during mouse ovarian aging

Bichun Guo, Sainan Zhang, Shanshan Wang, Huidan Zhang, Junshun Fang, Nannan Kang, Xin Zhen, Yang Zhang, Jidong Zhou, Guijun Yan, Haixiang Sun, Lijun Ding, Chuanming Liu

Reprod Biol Endocrinol. 2023; 21: 103. Published online 2023 Oct 31. doi: 10.1186/s12958-023-01147-w

PMCID:: PMC10617186

Abstract Article PDF–3.0M

Select item 88636639.

FOXP3/HAT1 Axis Controls Treg Infiltration in the Tumor Microenvironment by Inducing CCR4 Expression in Breast Cancer

Tania Sarkar, Subhanki Dhar, Dwaipayan Chakraborty, Subhadip Pati, Sayantan Bose, Abir K. Panda, Udit Basak, Sourio Chakraborty, Sumon Mukherjee, Aharna Guin, Kuladip Jana, Diptendra K. Sarkar, Gaurisankar Sa

Front Immunol. 2022; 13: 740588. Published online 2022 Feb 9. doi: 10.3389/fimmu.2022.740588

PMCID:: PMC8863663

Abstract Article PDF–16M

Select item 635976010.

Overexpressed histone acetyltransferase 1 regulates cancer immunity by increasing programmed death-ligand 1 expression in pancreatic cancer

Ping Fan, Jingyuan Zhao, Zibo Meng, Heyu Wu, Bo Wang, Heshui Wu, Xin Jin

J Exp Clin Cancer Res. 2019; 38: 47. Published online 2019 Feb 1. doi: 10.1186/s13046-019-1044-z

PMCID:: PMC6359760

Abstract Article PDF–5.7M

Select item 846460511.

Histone acetyltransferase 1 promotes gemcitabine resistance by regulating the PVT1/EZH2 complex in pancreatic cancer

Yan Sun, Dianyun Ren, Yingke Zhou, Jian Shen, Heshui Wu, Xin Jin

Cell Death Dis. 2021 Oct; 12(10): 878. Published online 2021 Sep 25. doi: 10.1038/s41419-021-04118-4

PMCID:: PMC8464605

Abstract Article PDF–6.1M

Select item 571423212.

PP32 and SET/TAF-Iβ proteins regulate the acetylation of newly synthesized histone H4

Francisco Saavedra, Carlos Rivera, Elizabeth Rivas, Paola Merino, Daniel Garrido, Sergio Hernández, Ignasi Forné, Isabelle Vassias, Zachary A. Gurard-Levin, Iván E. Alfaro, Axel Imhof, Geneviève Almouzni, Alejandra Loyola

Nucleic Acids Res. 2017 Nov 16; 45(20): 11700–11710. Published online 2017 Aug 30. doi: 10.1093/nar/gkx775

PMCID:: PMC5714232

Abstract Article PDF–960K

Select item 583010813.

AMPK promotes mitochondrial biogenesis and function by phosphorylating the epigenetic factors DNMT1, RBBP7, and HAT1

Traci L. Marin, Brendan Gongol, Fan Zhang, Marcy Martin, David A. Johnson, Han Xiao, Yinsheng Wang, Shankar Subramaniam, Shu Chien, John Y.-J. Shyy

Sci Signal. Author manuscript; available in PMC 2018 Feb 28.

Published in final edited form as: Sci Signal. 2017 Jan 31; 10(464): eaaf7478. Published online 2017 Jan 31. doi: 10.1126/scisignal.aaf7478

PMCID:: PMC5830108

Abstract Article PDF–1.0M

Select item 330728914.

Human Histone Acetyltransferase 1 Protein Preferentially Acetylates H4 Histone Molecules in H3.1-H4 over H3.3-H4

Hui Zhang, Junhong Han, Bin Kang, Rebecca Burgess, Zhiguo Zhang

J Biol Chem. 2012 Feb 24; 287(9): 6573–6581. Published online 2012 Jan 7. doi: 10.1074/jbc.M111.312637

PMCID:: PMC3307289

Abstract Article PDF–1.6M

Select item 405276715.

Hat2p recognizes the histone H3 tail to specify the acetylation of the newly synthesized H3/H4 heterodimer by the Hat1p/Hat2p complex

Yang Li, Li Zhang, Tingting Liu, Chengliang Chai, Qianglin Fang, Han Wu, Paula A. Agudelo Garcia, Zhifu Han, Shuai Zong, You Yu, Xinyue Zhang, Mark R. Parthun, Jijie Chai, Rui-Ming Xu, Maojun Yang

Genes Dev. 2014 Jun 1; 28(11): 1217–1227. doi: 10.1101/gad.240531.114