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Items: 1 to 20 of 85

1.
A Promoter Recognition Mechanism Common to Yeast Mitochondrial and Phage T7 RNA Polymerases
Dhananjaya Nayak, Qing Guo, Rui Sousa
J Biol Chem. 2009 May 15; 284(20): 13641–13647. doi: 10.1074/jbc.M900718200
PMCID:
PMC2679465
AbstractArticlePDF–796K
2.
Defective Mitochondrial Gene Expression Results in Reactive Oxygen Species-Mediated Inhibition of Respiration and Reduction of Yeast Life Span
Nicholas D. Bonawitz, Matthew S. Rodeheffer, Gerald S. Shadel
Mol Cell Biol. 2006 Jul; 26(13): 4818–4829. doi: 10.1128/MCB.02360-05
PMCID:
PMC1489155
AbstractArticlePDF–488K
3.
Characterization of the promoter of the large ribosomal RNA gene in yeast mitochondria and separation of mitochondrial RNA polymerase into two different functional components.
A H Schinkel, M J Groot Koerkamp, G T Van der Horst, E P Touw, K A Osinga, A M Van der Bliek, G H Veeneman, J H Van Boom, H F Tabak
EMBO J. 1986 May; 5(5): 1041–1047. doi: 10.1002/j.1460-2075.1986.tb04320.x
PMCID:
PMC1166899
SummaryPage BrowsePDF–1.7M
4.
Novel method for identifying sequence-specific DNA-binding proteins.
D Levens, P M Howley
Mol Cell Biol. 1985 Sep; 5(9): 2307–2315. doi: 10.1128/mcb.5.9.2307
PMCID:
PMC366957
SummaryPage BrowsePDF–1.9M
5.
RNA polymerase induces DNA bending at yeast mitochondrial promoters.
A H Schinkel, M J Groot Koerkamp, A W Teunissen, H F Tabak
Nucleic Acids Res. 1988 Oct 11; 16(19): 9147–9163. doi: 10.1093/nar/16.19.9147
PMCID:
PMC338697
SummaryPage BrowsePDF–2.4M
6.
Yeast RPO41 gene product is required for transcription and maintenance of the mitochondrial genome.
A L Greenleaf, J L Kelly, I R Lehman
Proc Natl Acad Sci U S A. 1986 May; 83(10): 3391–3394. doi: 10.1073/pnas.83.10.3391
PMCID:
PMC323519
SummaryPage BrowsePDF–1.0M
7.
The C-terminal Region of Mitochondrial Single-subunit RNA Polymerases Contains Species-specific Determinants for Maintenance of Intact Mitochondrial Genomes
Thomas Lisowsky, Detlef Wilkens, Torsten Stein, Boris Hedtke, Thomas Börner, Andreas Weihe
Mol Biol Cell. 2002 Jul; 13(7): 2245–2255. doi: 10.1091/mbc.01-07-0359
PMCID:
PMC117309
AbstractArticlePDF–337K
8.
Stability of the mitochondrial genome requires an amino-terminal domain of yeast mitochondrial RNA polymerase
Yuanhong Wang, Gerald S. Shadel
Proc Natl Acad Sci U S A. 1999 Jul 6; 96(14): 8046–8051. doi: 10.1073/pnas.96.14.8046
PMCID:
PMC22185
AbstractArticlePDF–184K
9.
Structures illustrate step-by-step mitochondrial transcription initiation
Quinten Goovaerts, Jiayu Shen, Brent De Wijngaert, Urmimala Basu, Smita S. Patel, Kalyan Das
Nature. 2023; 622(7984): 872–879. Published online 2023 Oct 11. doi: 10.1038/s41586-023-06643-y
PMCID:
PMC10600007
AbstractArticlePDF–13M
10.
Decreasing mitochondrial RNA polymerase activity reverses biased inheritance of hypersuppressive mtDNA
Daniel Corbi, Angelika Amon
PLoS Genet. 2021 Oct; 17(10): e1009808. Published online 2021 Oct 19. doi: 10.1371/journal.pgen.1009808
PMCID:
PMC8555793
AbstractArticlePDF–2.0M
11.
Cryo-EM structures reveal transcription initiation steps by yeast mitochondrial RNA polymerase
Brent De Wijngaert, Shemaila Sultana, Anupam Singh, Chhaya Dharia, Hans Vanbuel, Jiayu Shen, Daniel Vasilchuk, Sergio E. Martinez, Eaazhisai Kandiah, Smita S. Patel, Kalyan Das
Mol Cell. Author manuscript; available in PMC 2022 Jan 21.
Published in final edited form as: Mol Cell. 2021 Jan 21; 81(2): 268–280.e5. Published online 2020 Dec 4. doi: 10.1016/j.molcel.2020.11.016
PMCID:
PMC7855493
AbstractArticlePDF–2.9M
12.
The C-terminal tails of the mitochondrial transcription factors Mtf1 and TFB2M are part of an autoinhibitory mechanism that regulates DNA binding
Urmimala Basu, Nandini Mishra, Mohammed Farooqui, Jiayu Shen, Laura C. Johnson, Smita S. Patel
J Biol Chem. 2020 May 15; 295(20): 6823–6830. Published online 2020 Apr 2. doi: 10.1074/jbc.RA120.013338
PMCID:
PMC7242694
AbstractArticlePDF–1.5M
13.
The C-terminal tail of the yeast mitochondrial transcription factor Mtf1 coordinates template strand alignment, DNA scrunching and timely transition into elongation
Urmimala Basu, Seung-Won Lee, Aishwarya Deshpande, Jiayu Shen, Byeong-Kwon Sohn, Hayoon Cho, Hajin Kim, Smita S Patel
Nucleic Acids Res. 2020 Mar 18; 48(5): 2604–2620. Published online 2020 Jan 25. doi: 10.1093/nar/gkaa040
PMCID:
PMC7049685
AbstractArticlePDF–6.6M
14.
Highly efficient 5' capping of mitochondrial RNA with NAD+ and NADH by yeast and human mitochondrial RNA polymerase
Jeremy G Bird, Urmimala Basu, David Kuster, Aparna Ramachandran, Ewa Grudzien-Nogalska, Atif Towheed, Douglas C Wallace, Megerditch Kiledjian, Dmitry Temiakov, Smita S Patel, Richard H Ebright, Bryce E Nickels
eLife. 2018; 7: e42179. Published online 2018 Dec 12. doi: 10.7554/eLife.42179
PMCID:
PMC6298784
AbstractArticlePDF–1.5M
15.
Transcriptional fidelities of human mitochondrial POLRMT, yeast mitochondrial Rpo41, and phage T7 single-subunit RNA polymerases
Shemaila Sultana, Mihai Solotchi, Aparna Ramachandran, Smita S. Patel
J Biol Chem. 2017 Nov 3; 292(44): 18145–18160. Published online 2017 Sep 7. doi: 10.1074/jbc.M117.797480
PMCID:
PMC5672038
AbstractArticlePDF–4.5M
16.
The thumb subdomain of yeast mitochondrial RNA polymerase is involved in processivity, transcript fidelity and mitochondrial transcription factor binding
Gilberto Velazquez, Rui Sousa, Luis G Brieba
RNA Biol. 2015 May; 12(5): 514–524. Published online 2015 Feb 5. doi: 10.1080/15476286.2015.1014283
PMCID:
PMC4615813
AbstractArticlePDF–1.1M
17.
Yeast Mitochondrial Transcription Factor Mtf1 Determines the Precision of Promoter-Directed Initiation of RNA Polymerase Rpo41
Xu Yang, Hae Ryung Chang, Y. Whitney Yin
PLoS One. 2015; 10(9): e0136879. Published online 2015 Sep 2. doi: 10.1371/journal.pone.0136879
PMCID:
PMC4558008
AbstractArticlePDF–5.2M
18.
Double-stranded DNA-dependent ATPase Irc3p is directly involved in mitochondrial genome maintenance
Tiina Sedman, Ilja Gaidutšik, Karin Villemson, YingJian Hou, Juhan Sedman
Nucleic Acids Res. 2014 Dec 1; 42(21): 13214–13227. Published online 2014 Nov 11. doi: 10.1093/nar/gku1148
PMCID:
PMC4245962
AbstractArticlePDF–410K
19.
Interactions of the yeast mitochondrial RNA polymerase with the +1 and +2 promoter bases dictate transcription initiation efficiency
Aishwarya P. Deshpande, Smita S. Patel
Nucleic Acids Res. 2014 Oct 13; 42(18): 11721–11732. Published online 2014 Sep 23. doi: 10.1093/nar/gku868
PMCID:
PMC4191429
AbstractArticlePDF–3.3M
20.
Yeast mitochondrial RNAP conformational changes are regulated by interactions with the mitochondrial transcription factor
Srdja Drakulic, Liping Wang, Jorge Cuéllar, Qing Guo, Gilberto Velázquez, Jaime Martín-Benito, Rui Sousa, José M. Valpuesta
Nucleic Acids Res. 2014 Sep 29; 42(17): 11246–11260. Published online 2014 Sep 2. doi: 10.1093/nar/gku795
PMCID:
PMC4176174
AbstractArticlePDF–13M

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