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Select item 84900711.

Comprehensive Analysis of Glutamate-Rich WD Repeat-Containing Protein 1 and Its Potential Clinical Significance for Pancancer

Yumeng Wu, Xuming Wu, Yuanyuan Li, Wenjing Zhao, Yanping Yue, Biao Wu, Jibin Liu, Xudong Chen, Aiguo Shen

Biomed Res Int. 2021; 2021: 8201377. Published online 2021 Sep 27. doi: 10.1155/2021/8201377

PMCID:: PMC8490071

Abstract Article PDF–2.4M

Select item 25599062.

HBO1 histone acetylase is a coactivator of the replication licensing factor Cdt1

Benoit Miotto, Kevin Struhl

Genes Dev. 2008 Oct 1; 22(19): 2633–2638. doi: 10.1101/gad.1674108

PMCID:: PMC2559906

Abstract Article PDF–480K

Select item 52101533.

GRWD1 negatively regulates p53 via the RPL11–MDM2 pathway and promotes tumorigenesis

Kota Kayama, Shinya Watanabe, Takuya Takafuji, Takahiro Tsuji, Kensuke Hironaka, Masaki Matsumoto, Keiichi I Nakayama, Masato Enari, Takashi Kohno, Kouya Shiraishi, Tohru Kiyono, Kazumasa Yoshida, Nozomi Sugimoto, Masatoshi Fujita

EMBO Rep. 2017 Jan; 18(1): 123–137. Published online 2016 Nov 17. doi: 10.15252/embr.201642444

PMCID:: PMC5210153

Abstract Article PDF–1.3M

Select item 86895184.

GRWD1-WDR5-MLL2 Epigenetic Complex Mediates H3K4me3 Mark and Is Essential for Kaposi’s Sarcoma-Associated Herpesvirus-Induced Cellular Transformation

Shan Wei, Songjian Lu, Lifan Liang, Xian Wang, Wan Li, Tingting Li, Luping Chen, Enguo Ju, Xinquan Zhang, Zhao Lai, Yufei Huang, Xinghua Lu, Shou-Jiang Gao

mBio. 2021 Nov-Dec; 12(6): e03431-21. Published online 2021 Dec 21. doi: 10.1128/mbio.03431-21

PMCID:: PMC8689518

Abstract Article PDF–6.7M

Select item 44991375.

Cdt1-binding protein GRWD1 is a novel histone-binding protein that facilitates MCM loading through its influence on chromatin architecture

Nozomi Sugimoto, Kazumitsu Maehara, Kazumasa Yoshida, Shuhei Yasukouchi, Satoko Osano, Shinya Watanabe, Masahiro Aizawa, Takashi Yugawa, Tohru Kiyono, Hitoshi Kurumizaka, Yasuyuki Ohkawa, Masatoshi Fujita

Nucleic Acids Res. 2015 Jul 13; 43(12): 5898–5911. Published online 2015 May 18. doi: 10.1093/nar/gkv509

PMCID:: PMC4499137

Abstract Article PDF–8.4M

Select item 69296336.

Long noncoding RNA PiHL regulates p53 protein stability through GRWD1/RPL11/MDM2 axis in colorectal cancer

Xuan Deng, Sihan Li, Fanyang Kong, Haoyu Ruan, Xiao Xu, Xinju Zhang, Zhiyuan Wu, Lin Zhang, Ying Xu, Hong Yuan, Haixia Peng, Da Yang, Ming Guan

Theranostics. 2020; 10(1): 265–280. Published online 2020 Jan 1. doi: 10.7150/thno.36045

PMCID:: PMC6929633

Abstract Article PDF–3.0M

Select item 48094247.

Ubiquitin-specific protease 22 is a deubiquitinase of CCNB1

Zhenghong Lin, Can Tan, Quan Qiu, Sinyi Kong, Heeyoung Yang, Fang Zhao, Zhaojian Liu, Jinping Li, Qingfei Kong, Beixue Gao, Terry Barrett, Guang-Yu Yang, Jianing Zhang, Deyu Fang

Cell Discov. 2015; 1: 15028. Published online 2015 Oct 13. doi: 10.1038/celldisc.2015.28

PMCID:: PMC4809424

Abstract Article PDF–3.3M

Select item 22629958.

Identification of Novel Human Cdt1-binding Proteins by a Proteomics Approach: Proteolytic Regulation by APC/C^Cdh1

Nozomi Sugimoto, Issay Kitabayashi, Satoko Osano, Yasutoshi Tatsumi, Takashi Yugawa, Mako Narisawa-Saito, Akio Matsukage, Tohru Kiyono, Masatoshi Fujita

Mol Biol Cell. 2008 Mar; 19(3): 1007–1021. doi: 10.1091/mbc.E07-09-0859

PMCID:: PMC2262995

Abstract Article PDF–2.1M

Select item 98856509.

Long non-coding RNA SLC25A21-AS1 inhibits the development of epithelial ovarian cancer by specifically inducing PTBP3 degradation

Sihui Li, Shizhen Shen, Wanzhong Ge, Yixuan Cen, Songfa Zhang, Xiaodong Cheng, Xinyu Wang, Xing Xie, Weiguo Lu

Biomark Res. 2023; 11: 12. Published online 2023 Jan 30. doi: 10.1186/s40364-022-00432-x

Correction in:: Biomark Res. 2024; 12: 108.

PMCID:: PMC9885650

Abstract Article PDF–11M

Select item 162002510.

DDB1 functions as a linker to recruit receptor WD40 proteins to CUL4–ROC1 ubiquitin ligases

Yizhou Joseph He, Chad M. McCall, Jian Hu, Yaxue Zeng, Yue Xiong

Genes Dev. 2006 Nov 1; 20(21): 2949–2954. doi: 10.1101/gad.1483206

PMCID:: PMC1620025

Abstract Article PDF–420K

Select item 468305611.

Mixed Lineage Leukemia 5 (MLL5) Protein Stability Is Cooperatively Regulated by O-GlcNac Transferase (OGT) and Ubiquitin Specific Protease 7 (USP7)

Xiaodan Ding, Wei Jiang, Peipei Zhou, Lulu Liu, Xiaoling Wan, Xiujie Yuan, Xizi Wang, Miao Chen, Jun Chen, Jing Yang, Chao Kong, Bin Li, Chao Peng, Catherine C. L. Wong, Fajian Hou, Yan Zhang

PLoS One. 2015; 10(12): e0145023. Published online 2015 Dec 17. doi: 10.1371/journal.pone.0145023

PMCID:: PMC4683056

Abstract Article PDF–4.1M

Select item 413555112.

MDM2 Mediates Nonproteolytic Polyubiquitylation of the DEAD-Box RNA Helicase DDX24

Takayoshi Yamauchi, Masaaki Nishiyama, Toshiro Moroishi, Kanae Yumimoto, Keiichi I. Nakayama

Mol Cell Biol. 2014 Sep; 34(17): 3321–3340. doi: 10.1128/MCB.00320-14

PMCID:: PMC4135551

Abstract Article PDF–3.9M

Select item 576815013.

MicroRNA-300 Regulates the Ubiquitination of PTEN through the CRL4B^DCAF13 E3 Ligase in Osteosarcoma Cells

Zhi Chen, Wei Zhang, Kaibiao Jiang, Bin Chen, Kun Wang, Lifeng Lao, Canglong Hou, Fei Wang, Caiguo Zhang, Hongxing Shen

Mol Ther Nucleic Acids. 2018 Mar 2; 10: 254–268. Published online 2017 Dec 22. doi: 10.1016/j.omtn.2017.12.010

PMCID:: PMC5768150

Abstract Article PDF–2.7M

Select item 330886414.

Ubiquitin Ligase Substrate Identification through Quantitative Proteomics at Both the Protein and Peptide Levels

Kimberly A. Lee, Lisa P. Hammerle, Paul S. Andrews, Matthew P. Stokes, Tomas Mustelin, Jeffrey C. Silva, Roy A. Black, John R. Doedens

J Biol Chem. 2011 Dec 2; 286(48): 41530–41538. Published online 2011 Oct 10. doi: 10.1074/jbc.M111.248856

PMCID:: PMC3308864

Abstract Article PDF–815K

Select item 567959715.

Proteomic analysis reveals novel ligands and substrates for LNX1 E3 ubiquitin ligase

Joan A. Lenihan, Orthis Saha, Paul W. Young

PLoS One. 2017; 12(11): e0187352. Published online 2017 Nov 9. doi: 10.1371/journal.pone.0187352

PMCID:: PMC5679597

Abstract Article PDF–10M

Select item 795953416.

Blocking PPARγ interaction facilitates Nur77 interdiction of fatty acid uptake and suppresses breast cancer progression

Peng-bo Yang, Pei-pei Hou, Fu-yuan Liu, Wen-bin Hong, Hang-zi Chen, Xiao-yu Sun, Peng Li, Yi Zhang, Cui-yu Ju, Li-juan Luo, Sheng-fu Wu, Jia-xin Zhou, Zhi-jing Wang, Jian-ping He, Li Li, Tong-Jin Zhao, Xianming Deng, Tianwei Lin, Qiao Wu

Proc Natl Acad Sci U S A. 2020 Nov 3; 117(44): 27412–27422. Published online 2020 Oct 21. doi: 10.1073/pnas.2002997117