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Items: 1 to 20 of 67

1.
Inhibition of Wntless/GPR177 suppresses gastric tumorigenesis
Jaesung Seo, Hyun Jung Kee, Hye Ji Choi, Jae Eun Lee, Soo-Yeon Park, Seung-Hyun Lee, Mi-Hyeon Jeong, Garam Guk, SooYeon Lee, Kyung-Chul Choi, Yoon Young Choi, Hyunki Kim, Sung Hoon Noh, Ho-Geun Yoon, Jae-Ho Cheong
BMB Rep. 2018 May; 51(5): 255–260. Published online 2018 May 31. doi: 10.5483/BMBRep.2018.51.5.046
PMCID:
PMC5988581
AbstractArticlePDF–2.8M
2.
Genetic association study identified a 20 kb regulatory element in WLS associated with osteoporosis and bone mineral density in Han Chinese
Dangfeng Zhang, Zhaohui Ge, Xin Ma, Liqiang Zhi, Yunzhi Zhang, Xueyuan Wu, Shuxin Yao, Wei Ma
Sci Rep. 2017; 7: 13668. Published online 2017 Oct 20. doi: 10.1038/s41598-017-13932-w
PMCID:
PMC5651806
AbstractArticlePDF–1.2M
3.
Case-control association study of WLS variants in opioid and cocaine addicted populations
Richard C. Crist, Lisa M. Ambrose-Lanci, Angela Zeng, Cindy Yuan, Kyle M. Kampman, Helen M. Pettinati, David W. Oslin, Charles P. O’Brien, Thomas N. Ferraro, Glenn A. Doyle, Falk W. Lohoff, Wade H. Berrettini
Psychiatry Res. Author manuscript; available in PMC 2014 Jun 30.
Published in final edited form as: Psychiatry Res. 2013 Jun 30; 208(1): 62–66. Published online 2013 Apr 5. doi: 10.1016/j.psychres.2013.03.011
PMCID:
PMC3665700
AbstractArticlePDF–294K
4.
WLS inhibits melanoma cell proliferation through the β-catenin signalling pathway and induces spontaneous metastasis
Pei-Tzu Yang, Jamie N Anastas, Rachel A Toroni, Michi M Shinohara, Jamie M Goodson, Anja K Bosserhoff, Andy J Chien, Randall T Moon
EMBO Mol Med. 2012 Dec; 4(12): 1294–1307. Published online 2012 Nov 6. doi: 10.1002/emmm.201201486
PMCID:
PMC3531604
AbstractArticlePDF–858K
5.
The Wnt secretion protein Evi/Gpr177 promotes glioma tumourigenesis
Iris Augustin, Violaine Goidts, Angelika Bongers, Grainne Kerr, Gordon Vollert, Bernhard Radlwimmer, Christian Hartmann, Christel Herold-Mende, Guido Reifenberger, Andreas von Deimling, Michael Boutros
EMBO Mol Med. 2012 Jan; 4(1): 38–51. doi: 10.1002/emmm.201100186
PMCID:
PMC3306557
AbstractArticlePDF–525K
6.
Cryo-EM structure of human Wntless in complex with Wnt3a
Qing Zhong, Yanyu Zhao, Fangfei Ye, Zaiyu Xiao, Gaoxingyu Huang, Meng Xu, Yuanyuan Zhang, Xiechao Zhan, Ke Sun, Zhizhi Wang, Shanshan Cheng, Shan Feng, Xiuxiu Zhao, Jizhong Zhang, Peilong Lu, Wenqing Xu, Qiang Zhou, Dan Ma
Nat Commun. 2021; 12: 4541. Published online 2021 Jul 27. doi: 10.1038/s41467-021-24731-3
PMCID:
PMC8316347
AbstractArticlePDF–1.6M
7.
Structural basis of WLS/Evi-mediated Wnt transport and secretion
Rie Nygaard, Jia Yu, Jonathan Kim, Daniel Ross, Giacomo Parisi, Oliver B Clarke, David M Virshup, Filippo Mancia
Cell. Author manuscript; available in PMC 2022 Jan 7.
Published in final edited form as: Cell. 2021 Jan 7; 184(1): 194–206.e14. Published online 2020 Dec 23. doi: 10.1016/j.cell.2020.11.038
PMCID:
PMC7797000
AbstractArticlePDF–3.2M
8.
A Wntless–SEC12 complex on the ER membrane regulates early Wnt secretory vesicle assembly and mature ligand export
Jiaxin Sun, Shiyan Yu, Xiao Zhang, Catherine Capac, Onyedikachi Aligbe, Timothy Daudelin, Edward M. Bonder, Nan Gao
J Cell Sci. 2017 Jul 1; 130(13): 2159–2171. doi: 10.1242/jcs.200634
PMCID:
PMC5536887
AbstractArticle
9.
Focal Chromosomal Copy Number Aberrations Identify CMTM8 and GPR177 as New Candidate Driver Genes in Osteosarcoma
Joeri Both, Oscar Krijgsman, Johannes Bras, Gerard R. Schaap, Frank Baas, Bauke Ylstra, Theo J. M. Hulsebos
PLoS One. 2014; 9(12): e115835. Published online 2014 Dec 31. doi: 10.1371/journal.pone.0115835
PMCID:
PMC4281204
AbstractArticlePDF–1.4M
10.
A uniform human Wnt expression library reveals a shared secretory pathway and unique signaling activities
Rani Najdi, Kyle Proffitt, Stephanie Sprowl, Simran Kaur, Jia Yu, Tracy M. Covey, David M. Virshup, Marian L. Waterman
Differentiation. Author manuscript; available in PMC 2014 May 9.
Published in final edited form as: Differentiation. 2012 Sep; 84(2): 203–213. Published online 2012 Jul 9. doi: 10.1016/j.diff.2012.06.004
PMCID:
PMC4015730
AbstractArticlePDF–1.6M
11.
Wnt secretion is required to maintain high levels of Wnt activity in colon cancer cells
Oksana Voloshanenko, Gerrit Erdmann, Taronish D. Dubash, Iris Augustin, Marie Metzig, Giusi Moffa, Christian Hundsrucker, Grainne Kerr, Thomas Sandmann, Benedikt Anchang, Kubilay Demir, Christina Boehm, Svenja Leible, Claudia R. Ball, Hanno Glimm, Rainer Spang, Michael Boutros
Nat Commun. 2013 Oct 28; 4: 2610. Published online 2013 Oct 28. doi: 10.1038/ncomms3610
PMCID:
PMC3826636
AbstractArticlePDF–1.3M
12.
Targeted sequencing of genome wide significant loci associated with bone mineral density (BMD) reveals significant novel and rare variants: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study
Yi-Hsiang Hsu, Guo Li, Ching-Ti Liu, Jennifer A. Brody, David Karasik, Wen-Chi Chou, Serkalem Demissie, Kannabiran Nandakumar, Yanhua Zhou, Chia-Ho Cheng, Richard Gill, Richard A. Gibbs, Donna Muzny, Jireh Santibanez, Karol Estrada, Fernando Rivadeneira, Tamara Harris, Vilmundur Gudnason, Andre Uitterlinden, Bruce M Psaty, John A. Robbins, L Adrienne Cupples, Douglas P. Kiel
Hum Mol Genet. 2016 Dec 1; 25(23): 5234–5243. Published online 2016 Sep 11. doi: 10.1093/hmg/ddw289
PMCID:
PMC5837042
AbstractArticlePDF–435K
13.
Genome-wide association study using family-based cohorts identifies the WLS and CCDC170/ESR1 loci as associated with bone mineral density
Benjamin H. Mullin, John P. Walsh, Hou-Feng Zheng, Suzanne J. Brown, Gabriela L. Surdulescu, Charles Curtis, Gerome Breen, Frank Dudbridge, J. Brent Richards, Tim D. Spector, Scott G. Wilson
BMC Genomics. 2016; 17: 136. Published online 2016 Feb 25. doi: 10.1186/s12864-016-2481-0
PMCID:
PMC4766752
AbstractArticlePDF–1.9M
14.
Identification of an Endocytosis Motif in an Intracellular Loop of Wntless Protein, Essential for Its Recycling and the Control of Wnt Protein Signaling
Isabelle Gasnereau, Patrick Herr, Pei Zhi Cheryl Chia, Konrad Basler, Paul A. Gleeson
J Biol Chem. 2011 Dec 16; 286(50): 43324–43333. Published online 2011 Oct 25. doi: 10.1074/jbc.M111.307231
PMCID:
PMC3234804
AbstractArticlePDF–3.2M
15.
Expression of GPR177 (Wntless/Evi/Sprinter), a Highly Conserved Wnt-Transport Protein, in Rat Tissues, Zebrafish Embryos, and Cultured Human Cells
Jay Jin, Megan Morse, Colleen Frey, Jessica Petko, Robert Levenson
Dev Dyn. Author manuscript; available in PMC 2011 Sep 1.
Published in final edited form as: Dev Dyn. 2010 Sep; 239(9): 2426–2434. doi: 10.1002/dvdy.22369
PMCID:
PMC2939164
AbstractArticlePDF–1.2M
16.
EVI/WLS function is regulated by ubiquitylation and is linked to ER-associated degradation by ERLIN2
Lucie M. Wolf, Annika M. Lambert, Julie Haenlin, Michael Boutros
J Cell Sci. 2021 Aug 15; 134(16): jcs257790. Published online 2021 Aug 18. doi: 10.1242/jcs.257790
PMCID:
PMC8435288
AbstractArticle
17.
MicroRNA-31 Regulates Expression of Wntless in Both Drosophila melanogaster and Human Oral Cancer Cells
Ji Eun Jung, Joo Young Lee, In Ryoung Kim, Sang Mee Park, Ji Wan Kang, Yun Hak Kim, Hae Ryoun Park, Ji Hye Lee
Int J Mol Sci. 2020 Oct; 21(19): 7232. Published online 2020 Sep 30. doi: 10.3390/ijms21197232
PMCID:
PMC7582764
AbstractArticlePDF–1.8M
18.
Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis
Iris Augustin, Julia Gross, Daniel Baumann, Claudia Korn, Grainne Kerr, Tamara Grigoryan, Cornelia Mauch, Walter Birchmeier, Michael Boutros
J Exp Med. 2013 Aug 26; 210(9): 1761–1777. doi: 10.1084/jem.20121871
PMCID:
PMC3754868
AbstractArticlePDF–4.8M
19.
Interaction of the mu-opioid receptor with GPR177 (Wntless) inhibits Wnt secretion: potential implications for opioid dependence
Jay Jin, Saranya Kittanakom, Victoria Wong, Beverly AS Reyes, Elisabeth J Van Bockstaele, Igor Stagljar, Wade Berrettini, Robert Levenson
BMC Neurosci. 2010; 11: 33. Published online 2010 Mar 9. doi: 10.1186/1471-2202-11-33
PMCID:
PMC2841195
AbstractArticlePDF–2.2M
20.
Identifying novel members of the Wntless interactome through genetic and candidate gene approaches.
Jessica Petko, Trevor Tranchina, Goral Patel, Robert Levenson, Stephanie Justice-Bitner
Brain Res Bull. Author manuscript; available in PMC 2019 Jun 2.
Published in final edited form as: Brain Res Bull. 2018 Apr; 138: 96–105. Published online 2017 Jul 20. doi: 10.1016/j.brainresbull.2017.07.004
PMCID:
PMC6545234
AbstractArticlePDF–1.7M

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