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Items: 1 to 20 of 113

1.
Unraveling the Oncogenic Potential of VAV1 in Human Cancer: Lessons from Mouse Models
Batel Shalom, Yaser Salaymeh, Matan Risling, Shulamit Katzav
Cells. 2023 May; 12(9): 1276. Published online 2023 Apr 27. doi: 10.3390/cells12091276
PMCID:
PMC10177506
AbstractArticlePDF–2.5M
2.
Cancer‐associated mutations in VAV1 trigger variegated signaling outputs and T‐cell lymphomagenesis
Javier Robles‐Valero, Lucía Fernández‐Nevado, L Francisco Lorenzo‐Martín, Myriam Cuadrado, Isabel Fernández‐Pisonero, Sonia Rodríguez‐Fdez, Elsa N Astorga‐Simón, Antonio Abad, Rubén Caloto, Xosé R Bustelo
EMBO J. 2021 Nov 15; 40(22): e108125. Published online 2021 Oct 7. doi: 10.15252/embj.2021108125
PMCID:
PMC8591544
AbstractArticlePDF–4.9M
3.
Vav1 Sustains the In Vitro Differentiation of Normal and Tumor Precursors to Insulin Producing Cells Induced by all-Trans Retinoic Acid (ATRA)
Federica Brugnoli, Silvia Grassilli, Vincenzo Cardinale, Guido Carpino, Eugenio Gaudio, Domenico Alvaro, Silvano Capitani, Valeria Bertagnolo
Stem Cell Rev Rep. 2021; 17(2): 673–684. Published online 2020 Nov 9. doi: 10.1007/s12015-020-10074-x
PMCID:
PMC8036226
AbstractArticlePDF–5.3M
4.
New insights into the Vav1 activation cycle in lymphocytes
María Barreira, Sonia Rodríguez-Fdez, Xosé R. Bustelo
Cell Signal. Author manuscript; available in PMC 2024 Mar 13.
Published in final edited form as: Cell Signal. 2018 May 1; 45: 132–144. Published online 2018 Feb 2. doi: 10.1016/j.cellsig.2018.01.026
PMCID:
PMC7615736
AbstractArticlePDF–2.3M
5.
VAV1 Gene Polymorphisms in Patients with Rheumatoid Arthritis
Andrzej Pawlik, Damian Malinowski, Agnieszka Paradowska-Gorycka, Krzysztof Safranow, Violetta Dziedziejko
Int J Environ Res Public Health. 2020 May; 17(9): 3214. Published online 2020 May 5. doi: 10.3390/ijerph17093214
PMCID:
PMC7246862
AbstractArticlePDF–320K
6.
Activating mutations and translocations in the guanine exchange factor VAV1 in peripheral T-cell lymphomas
Francesco Abate, Ana C. da Silva-Almeida, Sakellarios Zairis, Javier Robles-Valero, Lucile Couronne, Hossein Khiabanian, S. Aidan Quinn, Mi-Yeon Kim, Maria Antonella Laginestra, Christine Kim, Danilo Fiore, Govind Bhagat, Miguel Angel Piris, Elias Campo, Izidore S. Lossos, Olivier A. Bernard, Giorgio Inghirami, Stefano Pileri, Xosé R. Bustelo, Raul Rabadan, Adolfo A. Ferrando, Teresa Palomero
Proc Natl Acad Sci U S A. 2017 Jan 24; 114(4): 764–769. Published online 2017 Jan 6. doi: 10.1073/pnas.1608839114
PMCID:
PMC5278460
AbstractArticlePDF–1.2M
7.
Mutation of Vav1 adaptor region reveals a new oncogenic activation
Lyra Razanadrakoto, Françoise Cormier, Vanessa Laurienté, Elisabetta Dondi, Laura Gardano, Shulamit Katzav, Lionel Guittat, Nadine Varin-Blank
Oncotarget. 2015 Feb; 6(4): 2524–2538. Published online 2014 Oct 24. doi: 10.18632/oncotarget.2629
PMCID:
PMC4385868
AbstractArticlePDF–6.0M
8.
Estrogen Induces Vav1 Expression in Human Breast Cancer Cells
Ming-juan Du, Xiang-dong Chen, Xiao-li Zhou, Ya-juan Wan, Bei Lan, Cui-zhu Zhang, Youjia Cao
PLoS One. 2014; 9(6): e99052. Published online 2014 Jun 6. doi: 10.1371/journal.pone.0099052
PMCID:
PMC4048212
AbstractArticlePDF–1.3M
9.
Vav1 as a Central Regulator of Invadopodia Assembly
Gina L. Razidlo, Barbara Schroeder, Jing Chen, Daniel D. Billadeau, Mark A. McNiven
Curr Biol. Author manuscript; available in PMC 2015 Jan 6.
Published in final edited form as: Curr Biol. 2014 Jan 6; 24(1): 86–93. Published online 2013 Dec 12. doi: 10.1016/j.cub.2013.11.013
PMCID:
PMC3917499
AbstractArticlePDF–885K
10.
The Amino-Terminus of Vav1 Regulates TCR-Induced SLP-76 Microclusters via the Calponin Homology Domain and Non-Catalytic Surfaces within the GEF Module
Nicholas R. Sylvain, Ken Nguyen, Stephen C. Bunnell
Sci Signal. Author manuscript; available in PMC 2013 Dec 12.
Published in final edited form as: Sci Signal. 2011 Mar 8; 4(163): 10.1126/scisignal.2001178. Published online 2011 Mar 8. doi: 10.1126/scisignal.2001178
PMCID:
PMC3860825
AbstractArticlePDF–5.3M
11.
T cell receptor-driven transendothelial migration of human effector memory CD4 T cells involves Vav, Rac and Myosin IIA
Thomas D. Manes, Jordan S. Pober
J Immunol. Author manuscript; available in PMC 2014 Apr 1.
Published in final edited form as: J Immunol. 2013 Apr 1; 190(7): 3079–3088. Published online 2013 Feb 18. doi: 10.4049/jimmunol.1201817
PMCID:
PMC3608744
AbstractArticlePDF–3.5M
12.
The N-terminal 20-Amino Acid Region of Guanine Nucleotide Exchange Factor Vav1 Plays a Distinguished Role in T Cell Receptor-mediated Calcium Signaling
Shi-Yang Li, Ming-Juan Du, Ya-Juan Wan, Bei Lan, Yao-Hui Liu, Yin Yang, Cui-Zhu Zhang, YouJia Cao
J Biol Chem. 2013 Feb 8; 288(6): 3777–3785. Published online 2012 Dec 27. doi: 10.1074/jbc.M112.426221
PMCID:
PMC3567632
AbstractArticlePDF–1.7M
13.
Vav1 Fine Tunes p53 Control of Apoptosis versus Proliferation in Breast Cancer
Shulamit Sebban, Marganit Farago, Dan Gashai, Lena Ilan, Eli Pikarsky, Ittai Ben-Porath, Shulamit Katzav
PLoS One. 2013; 8(1): e54321. Published online 2013 Jan 14. doi: 10.1371/journal.pone.0054321
PMCID:
PMC3544807
AbstractArticlePDF–1.0M
14.
Molecular Basis for Failure of “Atypical” C1 Domain of Vav1 to Bind Diacylglycerol/Phorbol Ester
Tamas Geczy, Megan L. Peach, Saïd El Kazzouli, Dina M. Sigano, Ji-Hye Kang, Christopher J. Valle, Julia Selezneva, Wonhee Woo, Noemi Kedei, Nancy E. Lewin, Susan H. Garfield, Langston Lim, Poonam Mannan, Victor E. Marquez, Peter M. Blumberg
J Biol Chem. 2012 Apr 13; 287(16): 13137–13158. Published online 2012 Feb 18. doi: 10.1074/jbc.M111.320010
PMCID:
PMC3340006
AbstractArticlePDF–4.9M
15.
Structural Basis of Guanine Nucleotide Exchange Mediated by the T-cell Essential Vav1
Jill E. Chrencik, Alexei Brooun, Hui Zhang, Irimpan I. Mathews, Greg L. Hura, Scott A. Foster, J. Jefferson P. Perry, Markus Streiff, Paul Ramage, Hans Widmer, Gary M. Bokoch, John Tainer, Gisbert Weckbecker, Peter Kuhn
J Mol Biol. Author manuscript; available in PMC 2009 Jul 25.
Published in final edited form as: J Mol Biol. 2008 Jul 25; 380(5): 828–843. Published online 2008 May 17. doi: 10.1016/j.jmb.2008.05.024
PMCID:
PMC2620086
AbstractArticlePDF–4.6M
16.
Mechanistic Analysis of the Amplification and Diversification Events Induced by Vav Proteins in B-lymphocytes
María J. Caloca, José L. Zugaza, Xosé R. Bustelo
J Biol Chem. 2008 Dec 26; 283(52): 36454–36464. doi: 10.1074/jbc.M803814200
PMCID:
PMC2606015
AbstractArticlePDF–686K
17.
The Src Homology 2 Domain of Vav Is Required for Its Compartmentation to the Plasma Membrane and Activation of C-Jun Nh2-Terminal Kinase 1
Ramachandran Arudchandran, Martin J. Brown, Matthew J. Peirce, James S. Song, Juan Zhang, Reuben P. Siraganian, Ulrich Blank, Juan Rivera
J Exp Med. 2000 Jan 3; 191(1): 47–60. doi: 10.1084/jem.191.1.47
PMCID:
PMC2195799
AbstractArticlePDF–590K
18.
Vav1 Acidic Region Tyrosine 174 Is Required for the Formation of T Cell Receptor-induced Microclusters and Is Essential in T Cell Development and Activation
Ana V. Miletic, Kumiko Sakata-Sogawa, Michio Hiroshima, Michael J. Hamann, Timothy S. Gomez, Naruhisa Ota, Tracie Kloeppel, Osami Kanagawa, Makio Tokunaga, Daniel D. Billadeau, Wojciech Swat
J Biol Chem. Author manuscript; available in PMC 2007 May 25.
Published in final edited form as: J Biol Chem. 2006 Dec 15; 281(50): 38257–38265. Published online 2006 Oct 18. doi: 10.1074/jbc.M608913200
PMCID:
PMC1876972
AbstractArticlePDF–654K
19.
Pleiotropic defects in TCR signaling in a Vav-1-null Jurkat T-cell line
Youjia Cao, Erin M. Janssen, Andrew W. Duncan, Amnon Altman, Daniel D. Billadeau, Robert T. Abraham
EMBO J. 2002 Sep 16; 21(18): 4809–4819. doi: 10.1093/emboj/cdf499
PMCID:
PMC126295
AbstractArticlePDF–391K
20.
RhoA G17E/Vav1 Signaling Induces Cancer Invasion via Matrix Metalloproteinase-9 in Gastric Cancer
Satoshi Nakamura, Masato Kitazawa, Yusuke Miyagawa, Makoto Koyama, Satoru Miyazaki, Nao Hondo, Futoshi Muranaka, Shigeo Tokumaru, Yuta Yamamoto, Takehito Ehara, Tomio Matsumura, Michiko Takeoka, Yuji Soejima
Technol Cancer Res Treat. 2023; 22: 15330338221146024. Published online 2023 Jan 9. doi: 10.1177/15330338221146024
PMCID:
PMC9834417
AbstractArticlePDF–5.8M

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