PMC Links for Gene (Select 73902) - PMC

Result Filters

Links from Gene

Items: 1 to 20 of 33

<< First< Prev

Page of 2

Select item 54365491.

A human PSMB11 variant affects thymoproteasome processing and CD8⁺ T cell production

Izumi Ohigashi, Yuki Ohte, Kazuya Setoh, Hiroshi Nakase, Akiko Maekawa, Hiroshi Kiyonari, Yoko Hamazaki, Miho Sekai, Tetsuo Sudo, Yasuharu Tabara, Hiromi Sawai, Yosuke Omae, Rika Yuliwulandari, Yasuhito Tanaka, Masashi Mizokami, Hiroshi Inoue, Masanori Kasahara, Nagahiro Minato, Katsushi Tokunaga, Keiji Tanaka, Fumihiko Matsuda, Shigeo Murata, Yousuke Takahama

JCI Insight. 2017 May 18; 2(10): e93664. Published online 2017 May 18. doi: 10.1172/jci.insight.93664

PMCID:: PMC5436549

Abstract Article PDF–1.1M

Select item 45572892.

Thymoproteasomes produce unique peptide motifs for positive selection of CD8⁺ T cells

Katsuhiro Sasaki, Kensuke Takada, Yuki Ohte, Hiroyuki Kondo, Hiroyuki Sorimachi, Keiji Tanaka, Yousuke Takahama, Shigeo Murata

Nat Commun. 2015; 6: 7484. Published online 2015 Jun 23. doi: 10.1038/ncomms8484

PMCID:: PMC4557289

Abstract Article PDF–802K

Select item 41161523.

Decreased Proteasomal Activity Causes Photoreceptor Degeneration in Mice

Ryo Ando, Kousuke Noda, Utano Tomaru, Mamoru Kamoshita, Yoko Ozawa, Shoji Notomi, Toshio Hisatomi, Mika Noda, Atsuhiro Kanda, Tatsuro Ishibashi, Masanori Kasahara, Susumu Ishida

Invest Ophthalmol Vis Sci. 2014 Jul; 55(7): 4682–4690. Published online 2014 Jul 30. doi: 10.1167/iovs.13-13272

PMCID:: PMC4116152

Abstract Article PDF–834K

Select item 101743294.

Klf4 protects thymus integrity during late pregnancy

Lucyle Depoërs, Maude Dumont-Lagacé, Vincent Quoc-Huy Trinh, Chloé Houques, Caroline Côté, Jean-David Larouche, Sylvie Brochu, Claude Perreault

Front Immunol. 2023; 14: 1016378. Published online 2023 Apr 27. doi: 10.3389/fimmu.2023.1016378

PMCID:: PMC10174329

Abstract Article PDF–9.7M

Select item 74900135.

Ageing compromises mouse thymus function and remodels epithelial cell differentiation

Jeanette Baran-Gale, Michael D Morgan, Stefano Maio, Fatima Dhalla, Irene Calvo-Asensio, Mary E Deadman, Adam E Handel, Ashley Maynard, Steven Chen, Foad Green, Rene V Sit, Norma F Neff, Spyros Darmanis, Weilun Tan, Andy P May, John C Marioni, Chris P Ponting, Georg A Holländer

eLife. 2020; 9: e56221. Published online 2020 Aug 25. doi: 10.7554/eLife.56221

PMCID:: PMC7490013

Abstract Article PDF–6.0M

Select item 68974926.

Trans-omics Impact of Thymoproteasome in Cortical Thymic Epithelial Cells

Izumi Ohigashi, Yu Tanaka, Kenta Kondo, Sayumi Fujimori, Hiroyuki Kondo, Amy C. Palin, Victoria Hoffmann, Mina Kozai, Yosuke Matsushita, Shinsuke Uda, Ryo Motosugi, Jun Hamazaki, Hiroyuki Kubota, Shigeo Murata, Keiji Tanaka, Toyomasa Katagiri, Hidetaka Kosako, Yousuke Takahama

Cell Rep. Author manuscript; available in PMC 2019 Dec 6.

Published in final edited form as: Cell Rep. 2019 Nov 26; 29(9): 2901–2916.e6. doi: 10.1016/j.celrep.2019.10.079

PMCID:: PMC6897492

Abstract Article PDF–2.7M

Select item 53098487.

Foxn1-β5t transcriptional axis controls CD8⁺ T-cell production in the thymus

Muhammad Myn Uddin, Izumi Ohigashi, Ryo Motosugi, Tomomi Nakayama, Mie Sakata, Jun Hamazaki, Yasumasa Nishito, Immanuel Rode, Keiji Tanaka, Tatsuya Takemoto, Shigeo Murata, Yousuke Takahama

Nat Commun. 2017; 8: 14419. Published online 2017 Feb 8. doi: 10.1038/ncomms14419

PMCID:: PMC5309848

Abstract Article PDF–1.8M

Select item 50330778.

Foxn1 regulates key target genes essential for T cell development in postnatal thymic epithelial cells

Saulius Žuklys, Adam Handel, Saule Zhanybekova, Fatima Govani, Marcel Keller, Stefano Maio, Carlos E. Mayer, Hong Ying Teh, Katrin Hafen, Giuseppe Gallone, Thomas Barthlott, Chris P. Ponting, Georg A. Holländer

Nat Immunol. Author manuscript; available in PMC 2017 Feb 22.

Published in final edited form as: Nat Immunol. 2016 Oct; 17(10): 1206–1215. Published online 2016 Aug 22. doi: 10.1038/ni.3537

PMCID:: PMC5033077

Abstract Article PDF–2.4M

Select item 48323419.

Dynamic spatio‐temporal contribution of single β5t+ cortical epithelial precursors to the thymus medulla

Carlos E. Mayer, Saulius Žuklys, Saule Zhanybekova, Izumi Ohigashi, Hong‐Ying Teh, Stephen N. Sansom, Noriko Shikama‐Dorn, Katrin Hafen, Iain C. Macaulay, Mary E. Deadman, Chris P. Ponting, Yousuke Takahama, Georg A. Holländer

Eur J Immunol. 2016 Apr; 46(4): 846–856. Published online 2016 Jan 18. doi: 10.1002/eji.201545995

PMCID:: PMC4832341

Abstract Article PDF–2.0M

Select item 368372610.

Aire-expressing thymic medullary epithelial cells originate from β5t-expressing progenitor cells

Izumi Ohigashi, Saulius Zuklys, Mie Sakata, Carlos E. Mayer, Saule Zhanybekova, Shigeo Murata, Keiji Tanaka, Georg A. Holländer, Yousuke Takahama

Proc Natl Acad Sci U S A. 2013 Jun 11; 110(24): 9885–9890. Published online 2013 May 29. doi: 10.1073/pnas.1301799110

PMCID:: PMC3683726

Abstract Article PDF–1.2M

Select item 352857711.

Thymic nurse cells provide microenvironment for secondary T cell receptor α rearrangement in cortical thymocytes

Yasushi Nakagawa, Izumi Ohigashi, Takeshi Nitta, Mie Sakata, Keiji Tanaka, Shigeo Murata, Osami Kanagawa, Yousuke Takahama

Proc Natl Acad Sci U S A. 2012 Dec 11; 109(50): 20572–20577. Published online 2012 Nov 27. doi: 10.1073/pnas.1213069109

PMCID:: PMC3528577

Abstract Article PDF–1.1M

Select item 665034912.

Identification of an intronic regulatory element necessary for tissue-specific expression of Foxn1 in thymic epithelial cells

Brian M. Larsen, Jennifer E. Cowan, Yueqiang Wang, Yu Tanaka, Yongge Zhao, Benjamin Voisin, Michael G. Constantinides, Keisuke Nagao, Yasmine Belkaid, Parirokh Awasthi, Yousuke Takahama, Avinash Bhandoola

J Immunol. Author manuscript; available in PMC 2020 Aug 1.

Published in final edited form as: J Immunol. 2019 Aug 1; 203(3): 686–695. Published online 2019 Jun 26. doi: 10.4049/jimmunol.1801540

PMCID:: PMC6650349

Abstract Article PDF–1.9M

Select item 481078213.

TCR affinity for thymoproteasome-dependent positively selecting peptides conditions antigen responsiveness in CD8⁺ T cells

Kensuke Takada, Francois Van Laethem, Yan Xing, Kazuyuki Akane, Haruhiko Suzuki, Shigeo Murata, Keiji Tanaka, Stephen C. Jameson, Alfred Singer, Yousuke Takahama

Nat Immunol. Author manuscript; available in PMC 2016 Mar 29.

Published in final edited form as: Nat Immunol. 2015 Oct; 16(10): 1069–1076. Published online 2015 Aug 24. doi: 10.1038/ni.3237

PMCID:: PMC4810782

Abstract Article PDF–1.7M

Select item 949526114.

IL-2 and IL-15 drive intrathymic development of distinct periphery-seeding CD4⁺Foxp3⁺ regulatory T lymphocytes

Cécile Apert, Ariel O. Galindo-Albarrán, Sarah Castan, Claire Detraves, Héloise Michaud, Nicola McJannett, Bart Haegeman, Simon Fillatreau, Bernard Malissen, Georg Holländer, Saulius Žuklys, Jérémy C. Santamaria, Olivier P. Joffre, Paola Romagnoli, Joost P. M. van Meerwijk

Front Immunol. 2022; 13: 965303. Published online 2022 Sep 8. doi: 10.3389/fimmu.2022.965303