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Select item 86390821.

Nucleoporin TPR promotes tRNA nuclear export and protein synthesis in lung cancer cells

Miao Chen, Qian Long, Melinda S. Borrie, Haohui Sun, Changlin Zhang, Han Yang, Dingbo Shi, Marc R. Gartenberg, Wuguo Deng

PLoS Genet. 2021 Nov; 17(11): e1009899. Published online 2021 Nov 18. doi: 10.1371/journal.pgen.1009899

PMCID:: PMC8639082

Abstract Article PDF–3.1M

Select item 82258032.

The human nucleoporin Tpr protects cells from RNA-mediated replication stress

Martin Kosar, Michele Giannattasio, Daniele Piccini, Apolinar Maya-Mendoza, Francisco García-Benítez, Jirina Bartkova, Sonia I. Barroso, Hélène Gaillard, Emanuele Martini, Umberto Restuccia, Miguel Angel Ramirez-Otero, Massimiliano Garre, Eleonora Verga, Miguel Andújar-Sánchez, Scott Maynard, Zdenek Hodny, Vincenzo Costanzo, Amit Kumar, Angela Bachi, Andrés Aguilera, Jiri Bartek, Marco Foiani

Nat Commun. 2021; 12: 3937. Published online 2021 Jun 24. doi: 10.1038/s41467-021-24224-3

PMCID:: PMC8225803

Abstract Article PDF–4.4M

Select item 76724583.

TPR is required for the efficient nuclear export of mRNAs and lncRNAs from short and intron-poor genes

Eliza S Lee, Eric J Wolf, Sean S J Ihn, Harrison W Smith, Andrew Emili, Alexander F Palazzo

Nucleic Acids Res. 2020 Nov 18; 48(20): 11645–11663. Published online 2020 Oct 22. doi: 10.1093/nar/gkaa919

PMCID:: PMC7672458

Abstract Article PDF–13M

Select item 63628084.

Nuclear pore density controls heterochromatin reorganization during senescence

Charlene Boumendil, Priya Hari, Karl C.F. Olsen, Juan Carlos Acosta, Wendy A. Bickmore

Genes Dev. 2019 Feb 1; 33(3-4): 144–149. doi: 10.1101/gad.321117.118

PMCID:: PMC6362808

Abstract Article PDF–4.5M

Select item 57226455.

A new role for the nuclear basket network

Paola Gallardo, Silvia Salas-Pino, Rafael R. Daga

Microb Cell. 2017 Dec 4; 4(12): 423–425. Published online 2017 Nov 27. doi: 10.15698/mic2017.12.604

PMCID:: PMC5722645

Abstract Article PDF–832K

Select item 35018236.

Regulation of autophagy by nucleoporin Tpr

Tatsuyoshi Funasaka, Eriko Tsuka, Richard W. Wong

Sci Rep. 2012; 2: 878. Published online 2012 Nov 20. doi: 10.1038/srep00878

PMCID:: PMC3501823

Abstract Article PDF–2.3M

Select item 31396447.

Silencing Nuclear Pore Protein Tpr Elicits a Senescent-Like Phenotype in Cancer Cells

Brigitte David-Watine

PLoS One. 2011; 6(7): e22423. Published online 2011 Jul 19. doi: 10.1371/journal.pone.0022423

PMCID:: PMC3139644

Abstract Article PDF–567K

Select item 21202838.

Tpr, a large coiled coil protein whose amino terminus is involved in activation of oncogenic kinases, is localized to the cytoplasmic surface of the nuclear pore complex

J Cell Biol. 1994 Dec 2; 127(6): 1515–1526. doi: 10.1083/jcb.127.6.1515

PMCID:: PMC2120283

Summary PDF–2.3M

Select item 2794739.

Characterization of the TPR-MET oncogene p65 and the MET protooncogene p140 protein-tyrosine kinases.

M Gonzatti-Haces, A Seth, M Park, T Copeland, S Oroszlan, G F Vande Woude

Proc Natl Acad Sci U S A. 1988 Jan; 85(1): 21–25. doi: 10.1073/pnas.85.1.21

PMCID:: PMC279473

Summary Page Browse PDF–1.7M

Select item 550762610.

Structural basis of TPR mediated oligomerization and activation of oncogenic fusion kinases

Kuntal Pal, Abhishek Bandyopadhyay, X. Edward Zhou, Qingping Xu, David P. Marciano, Joseph S. Brunzelle, Smitha Yerrum, Patrick R. Griffin, George Vande Woude, Karsten Melcher, H. Eric Xu

Structure. Author manuscript; available in PMC 2018 Jun 6.

Published in final edited form as: Structure. 2017 Jun 6; 25(6): 867–877.e3. Published online 2017 May 18. doi: 10.1016/j.str.2017.04.015

PMCID:: PMC5507626

Abstract Article PDF–2.5M

Select item 546208111.

AKAP95 interacts with nucleoporin TPR in mitosis and is important for the spindle assembly checkpoint

Graciela López-Soop, Torunn Rønningen, Agnieszka Rogala, Nina Richartz, Heidi Kiil Blomhoff, Bernd Thiede, Philippe Collas, Thomas Küntziger

Cell Cycle. 2017; 16(10): 947–956. Published online 2017 Apr 5. doi: 10.1080/15384101.2017.1310350

PMCID:: PMC5462081

Abstract Article PDF–1.0M

Select item 461490312.

Therapeutic potential of mitotic interaction between the nucleoporin Tpr and aurora kinase A

Akiko Kobayashi, Chieko Hashizume, Takayuki Dowaki, Richard W Wong

Cell Cycle. 2015 May 1; 14(9): 1447–1458. Published online 2015 Mar 19. doi: 10.1080/15384101.2015.1021518

PMCID:: PMC4614903

Abstract Article PDF–1.2M

Select item 365335113.

Defective nuclear import of Tpr in Progeria reflects the Ran sensitivity of large cargo transport

Chelsi J. Snow, Ashraf Dar, Anindya Dutta, Ralph H. Kehlenbach, Bryce M. Paschal

J Cell Biol. 2013 May 13; 201(4): 541–557. doi: 10.1083/jcb.201212117

PMCID:: PMC3653351

Abstract Article PDF–5.7M

Select item 217521614.

Functional Analysis of Tpr: Identification of Nuclear Pore Complex Association and Nuclear Localization Domains and a Role in mRNA Export

Peter Bangs, Brian Burke, Christine Powers, Roger Craig, Aruna Purohit, Stephen Doxsey

J Cell Biol. 1998 Dec 28; 143(7): 1801–1812. doi: 10.1083/jcb.143.7.1801

PMCID:: PMC2175216

Abstract Article PDF–937K

Select item 5860515.

Amino Acid Substitutions of Coiled-Coil Protein Tpr Abrogate Anchorage to the Nuclear Pore Complex but Not Parallel, In-Register Homodimerization

Manuela E. Hase, Nikolai V. Kuznetsov, Volker C. Cordes

Mol Biol Cell. 2001 Aug; 12(8): 2433–2452. doi: 10.1091/mbc.12.8.2433

PMCID:: PMC58605

Abstract Article PDF–1.3M

Select item 3063216.

The nucleoporin Nup98 associates with the intranuclear filamentous protein network of TPR

Beatriz M. A. Fontoura, Samuel Dales, Günter Blobel, Hualin Zhong

Proc Natl Acad Sci U S A. 2001 Mar 13; 98(6): 3208–3213. doi: 10.1073/pnas.061014698

PMCID:: PMC30632

Abstract Article PDF–1.0M

Select item 1110545317.

Nuclear pore protein TPR associates with lamin B1 and affects nuclear lamina organization and nuclear pore distribution

Jindřiška Fišerová, Miloslava Maninová, Tomáš Sieger, Jana Uhlířová, Lenka Šebestová, Michaela Efenberková, Martin Čapek, Karel Fišer, Pavel Hozák

Cell Mol Life Sci. 2019 Jun; 76(11): 2199–2216. Published online 2019 Feb 14. doi: 10.1007/s00018-019-03037-0

PMCID:: PMC11105453

Abstract Article PDF–4.1M

Select item 807876218.

Nucleoporin TPR (translocated promoter region, nuclear basket protein) upregulation alters MTOR-HSF1 trails and suppresses autophagy induction in ependymoma

Firli Rahmah Primula Dewi, Shabierjiang Jiapaer, Akiko Kobayashi, Masaharu Hazawa, Dini Kurnia Ikliptikawati, Hartono, Hemragul Sabit, Mitsutoshi Nakada, Richard W. Wong

Autophagy. 2021; 17(4): 1001–1012. Published online 2020 Mar 24. doi: 10.1080/15548627.2020.1741318

PMCID:: PMC8078762

Abstract Article PDF–4.6M

Select item 398311219.

The Interaction of CRM1 and the Nuclear Pore Protein Tpr

Charles L. Zhao, Seyed Hanif Mahboobi, Ruhollah Moussavi-Baygi, Mohammad R. K. Mofrad

PLoS One. 2014; 9(4): e93709. Published online 2014 Apr 10. doi: 10.1371/journal.pone.0093709

PMCID:: PMC3983112

Abstract Article PDF–11M

Select item 339994920.

The health benefits of dietary fiber: beyond the usual suspects of type 2 diabetes, cardiovascular disease and colon cancer

Melissa M. Kaczmarczyk, Michael J. Miller, Gregory G. Freund

Metabolism. Author manuscript; available in PMC 2013 Aug 1.

Published in final edited form as: Metabolism. 2012 Aug; 61(8): 1058–1066. Published online 2012 Mar 7. doi: 10.1016/j.metabol.2012.01.017

PMCID:: PMC3399949

Abstract Article PDF–312K

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