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Select item 86029301.

High TSPAN8 expression in epithelial cancer cell‐derived small extracellular vesicles promote confined diffusion and pronounced uptake

Teng Wang, Xin Wang, Haobin Wang, Luhan Li, Chenhong Zhang, Rong Xiang, Xiaoyue Tan, Zongjin Li, Chunyang Jiang, Lei Zheng, Lehui Xiao, Shijing Yue

J Extracell Vesicles. 2021 Nov; 10(13): e12167. Published online 2021 Nov 18. doi: 10.1002/jev2.12167

PMCID:: PMC8602930

Abstract Article PDF–4.2M

Select item 84871262.

Tetraspanin8 expression predicts an increased metastatic risk and is associated with cancer-related death in human cutaneous melanoma

Odile Berthier-Vergnes, Laetitia Barbollat-Boutrand, Roxane M. Pommier, Arnaud de la Fouchardière, Patrick Combemale, Maxime Grimont, Noémie Lopez-Ramirez, Julie Caramel, Stéphane Dalle, Jean-Luc Perrot, Caroline Gaudy-Marqueste, Nicolas Macagno, Sandrine Mansard, Fanny Bouquet, Ingrid Masse

Mol Cancer. 2021; 20: 127. Published online 2021 Oct 2. doi: 10.1186/s12943-021-01429-0

PMCID:: PMC8487126

Article PDF–1.1M

Select item 71752993.

TSPAN8 as a Novel Emerging Therapeutic Target in Cancer for Monoclonal Antibody Therapy

Kyun Heo, Sukmook Lee

Biomolecules. 2020 Mar; 10(3): 388. Published online 2020 Mar 3. doi: 10.3390/biom10030388

PMCID:: PMC7175299

Abstract Article PDF–676K

Select item 54323484.

Multi-factorial modulation of colorectal carcinoma cells motility – partial coordination by the tetraspanin Co-029/tspan8

Yingying Zhu, Naouel Ailane, Monica Sala-Valdés, Farhad Haghighi-Rad, Martine Billard, Viet Nguyen, Raphael Saffroy, Antoinette Lemoine, Eric Rubinstein, Claude Boucheix, Céline Greco

Oncotarget. 2017 Apr 18; 8(16): 27454–27470. Published online 2017 Mar 16. doi: 10.18632/oncotarget.16247

PMCID:: PMC5432348

Abstract Article PDF–4.0M

Select item 33679725.

Tetraspanin CO-029 Inhibits Colorectal Cancer Cell Movement by Deregulating Cell-Matrix and Cell-Cell Adhesions

Qiusha Guo, Bing Xia, Feng Zhang, Mekel M. Richardson, Minghao Li, Julian S. Zhang, Feng Chen, Xin A. Zhang

PLoS One. 2012; 7(6): e38464. Published online 2012 Jun 5. doi: 10.1371/journal.pone.0038464

PMCID:: PMC3367972

Abstract Article PDF–1.7M

Select item 30397986.

Gene expression profiles of human melanoma cells with different invasive potential reveal TSPAN8 as a novel mediator of invasion

O Berthier-Vergnes, M El Kharbili, A de la Fouchardière, T Pointecouteau, P Verrando, A Wierinckx, J Lachuer, F Le Naour, J Lamartine

Br J Cancer. 2011 Jan 4; 104(1): 155–165. Published online 2010 Nov 16. doi: 10.1038/sj.bjc.6605994

PMCID:: PMC3039798

Abstract Article PDF–810K

Select item 546327.

Molecular cloning of cDNA for the human tumor-associated antigen CO-029 and identification of related transmembrane antigens.

S Szala, Y Kasai, Z Steplewski, U Rodeck, H Koprowski, A J Linnenbach

Proc Natl Acad Sci U S A. 1990 Sep; 87(17): 6833–6837. doi: 10.1073/pnas.87.17.6833

PMCID:: PMC54632

Summary Page Browse PDF–1.4M

Select item 83218998.

SOX9 is a critical regulator of TSPAN8-mediated metastasis in pancreatic cancer

Junjian Li, Xiaoliang Chen, Liqun Zhu, Zhenghong Lao, Tianhao Zhou, Lijuan Zang, Weiyu Ge, Mengyi Jiang, Jingxuan Xu, Yuan Cao, Shaoqian Du, Yue Yu, Guangjian Fan, Hongxia Wang

Oncogene. 2021; 40(30): 4884–4893. Published online 2021 Jun 23. doi: 10.1038/s41388-021-01864-9

PMCID:: PMC8321899

Abstract Article PDF–3.3M

Select item 70658899.

Extracellular vesicle tetraspanin-8 level predicts distant metastasis in non–small cell lung cancer after concurrent chemoradiation

Yang Liu, Jia Fan, Ting Xu, Navid Ahmadinejad, Kenneth Hess, Steven H. Lin, Jianjun Zhang, Xi Liu, Li Liu, Bo Ning, Zhongxing Liao, Tony Y. Hu

Sci Adv. 2020 Mar; 6(11): eaaz6162. Published online 2020 Mar 11. doi: 10.1126/sciadv.aaz6162

PMCID:: PMC7065889

Abstract Article PDF–2.3M

Select item 692955910.

A Positive Tetraspanin 8 (TSPAN8)/β-Catenin Regulatory Loop Enhances the Stemness of Colorectal Cancer Cells

Zhengyu Zhan, Luxing Zhong, Miao Feng, Yuling Guo

Med Sci Monit. 2019; 25: 9594–9601. Published online 2019 Dec 15. doi: 10.12659/MSM.919749

PMCID:: PMC6929559

Abstract Article PDF–1.6M

Select item 513003211.

Tetraspanin-8 promotes hepatocellular carcinoma metastasis by increasing ADAM12m expression

Tingting Fang, Jiajia Lin, Yanru Wang, Guangnan Chen, Jing Huang, Jie Chen, Yan Zhao, Ruixia Sun, Chunmin Liang, Binbin Liu

Oncotarget. 2016 Jun 28; 7(26): 40630–40643. Published online 2016 Jun 1. doi: 10.18632/oncotarget.9769

PMCID:: PMC5130032

Abstract Article PDF–6.6M

Select item 499243712.

Tetraspanin 8 (TSPAN8) mediates AEG-1-induced invasion and metastasis in hepatocellular carcinoma (HCC) cells

Maaged A. Akiel, Prasanna K. Santhekadur, Rachel G. Mendoza, Ayesha Siddiq, Paul B. Fisher, Devanand Sarkar

FEBS Lett. Author manuscript; available in PMC 2017 Aug 1.

Published in final edited form as: FEBS Lett. 2016 Aug; 590(16): 2700–2708. Published online 2016 Jul 21. doi: 10.1002/1873-3468.12268

PMCID:: PMC4992437

Abstract Article PDF–859K

Select item 469562913.

TM4SF3 and AR: A Nuclear Complex that Stabilizes Both Proteins

Meenakshi Bhansali, Jun Zhou, Lirim Shemshedini

Mol Endocrinol. 2016 Jan; 30(1): 13–25. Published online 2015 Dec 9. doi: 10.1210/me.2015-1075

PMCID:: PMC4695629

Abstract Article

Select item 289233914.

Genome-wide association study of copy number variation in 16,000 cases of eight common diseases and 3,000 shared controls

The Wellcome Trust Case Control Consortium

Nature. Author manuscript; available in PMC 2010 Oct 1.

Published in final edited form as: Nature. 2010 Apr 1; 464(7289): 713–720. doi: 10.1038/nature08979

PMCID:: PMC2892339

Abstract Article PDF–1.3M

Select item 1125857015.

New insights into the role of tetraspanin 6, 7, and 8 in physiology and pathology

Monika Mrozowska, Tomasz Górnicki, Mateusz Olbromski, Aleksandra Izabela Partyńska, Piotr Dzięgiel, Agnieszka Rusak

Cancer Med. 2024 Jul; 13(14): e7390. Published online 2024 Jul 19. doi: 10.1002/cam4.7390

PMCID:: PMC11258570

Abstract Article PDF–1.3M

Select item 897583116.

EGFR signaling promotes nuclear translocation of plasma membrane protein TSPAN8 to enhance tumor progression via STAT3-mediated transcription

Xiaoqing Lu, Liwei An, Guangjian Fan, Lijuan Zang, Weiyi Huang, Junjian Li, Jun Liu, Weiyu Ge, Yuwei Huang, Jingxuan Xu, Shaoqian Du, Yuan Cao, Tianhao Zhou, Huijing Yin, Li Yu, Shi Jiao, Hongxia Wang

Cell Res. 2022 Apr; 32(4): 359–374. Published online 2022 Feb 23. doi: 10.1038/s41422-022-00628-8

PMCID:: PMC8975831

Abstract Article PDF–8.3M

Select item 793596317.

Identification of CD318, TSPAN8 and CD66c as target candidates for CAR T cell based immunotherapy of pancreatic adenocarcinoma

Daniel Schäfer, Stefan Tomiuk, Laura N. Küster, Wa’el Al Rawashdeh, Janina Henze, German Tischler-Höhle, David J. Agorku, Janina Brauner, Cathrin Linnartz, Dominik Lock, Andrew Kaiser, Christoph Herbel, Dominik Eckardt, Melina Lamorte, Dorothee Lenhard, Julia Schüler, Philipp Ströbel, Jeannine Missbach-Guentner, Diana Pinkert-Leetsch, Frauke Alves, Andreas Bosio, Olaf Hardt

Nat Commun. 2021; 12: 1453. Published online 2021 Mar 5. doi: 10.1038/s41467-021-21774-4

PMCID:: PMC7935963

Abstract Article PDF–6.6M

Select item 537002918.

Tetraspanin 8 is a novel regulator of ILK-driven β1 integrin adhesion and signaling in invasive melanoma cells

Manale El Kharbili, Clément Robert, Tiffany Witkowski, Emmanuelle Danty-Berger, Laetitia Barbollat-Boutrand, Ingrid Masse, Nicolas Gadot, Arnaud de la Fouchardière, Paul C McDonald, Shoukat Dedhar, François Le Naour, Françoise Degoul, Odile Berthier-Vergnes

Oncotarget. 2017 Mar 7; 8(10): 17140–17155. Published online 2017 Feb 4. doi: 10.18632/oncotarget.15084

PMCID:: PMC5370029

Abstract Article PDF–9.8M

Select item 677182519.

Tspan8 is expressed in breast cancer and regulates E‐cadherin/catenin signalling and metastasis accompanied by increased circulating extracellular vesicles

Maren Voglstaetter, Andreas R Thomsen, Jerome Nouvel, Arend Koch, Paul Jank, Elena Grueso Navarro, Tanja Gainey‐Schleicher, Richa Khanduri, Andrea Groß, Florian Rossner, Carina Blaue, Clemens M Franz, Marina Veil, Gerhard Puetz, Andreas Hippe, Jochen Dindorf, Jubin Kashef, Wilko Thiele, Bernhard Homey, Celine Greco, Claude Boucheix, Andreas Baur, Thalia Erbes, Cornelius F Waller, Marie Follo, Ghamartaj Hossein, Christine Sers, Jonathan Sleeman, Irina Nazarenko

J Pathol. 2019 Aug; 248(4): 421–437. Published online 2019 Jun 18. doi: 10.1002/path.5281

PMCID:: PMC6771825

Abstract Article PDF–5.7M

Select item 377781620.

Whole-genome Association Study of Bipolar Disorder

P Sklar, JW Smoller, J Fan, MAR Ferreira, RH Perlis, K Chambert, VL Nimgaonkar, MB McQueen, SV Faraone, A Kirby, PIW de Bakker, MN Ogdie, ME Thase, GS Sachs, K Todd-Brown, SB Gabriel, C Sougnez, C Gates, B Blumenstiel, M Defelice, KG Ardlie, J Franklin, WJ Muir, KA McGhee, DM MacIntyre, A McLean, M VanBeck, A McQuillin, NJ Bass, M Robinson, J Lawrence, A Anjorin, D Curtis, EM Scolnick, MJ Daly, DH Blackwood, HM Gurling, SM Purcell

Mol Psychiatry. Author manuscript; available in PMC 2013 Sep 19.

Published in final edited form as: Mol Psychiatry. 2008 Jun; 13(6): 558–569. Published online 2008 Mar 4. doi: 10.1038/sj.mp.4002151

PMCID:: PMC3777816

Abstract Article PDF–475K

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