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Select item 103713401.

TIAM1 acts as an actin organization regulator to control adipose tissue–derived pericyte cell fate

Ginny Ching-Yun Hsu, Yiyun Wang, Amy Z. Lu, Mario A. Gomez-Salazar, Jiajia Xu, Dongqing Li, Carolyn Meyers, Stefano Negri, Sintawat Wangsiricharoen, Kristen Broderick, Bruno Peault, Carol Morris, Aaron W. James

JCI Insight. 2023 Jul 10; 8(13): e159141. Published online 2023 Jul 10. doi: 10.1172/jci.insight.159141

PMCID:: PMC10371340

Abstract Article PDF–13M

Select item 68556402.

Tiam1 high expression is associated with poor prognosis in solid cancers: A meta-analysis

Jianlong Ding, Fan Yang, WeiFeng Wu

Medicine (Baltimore) 2019 Nov; 98(45): e17529. Published online 2019 Nov 11. doi: 10.1097/MD.0000000000017529

PMCID:: PMC6855640

Abstract Article PDF–842K

Select item 64250433.

TIAM1 promotes chemoresistance and tumor invasiveness in colorectal cancer

Daisuke Izumi, Shusuke Toden, Elsie Ureta, Takatsugu Ishimoto, Hideo Baba, Ajay Goel

Cell Death Dis. 2019 Apr; 10(4): 267. Published online 2019 Mar 19. doi: 10.1038/s41419-019-1493-5

PMCID:: PMC6425043

Abstract Article PDF–1.3M

Select item 60956424.

Competition between TIAM1 and membranes balances Endophilin A3 activity in cancer metastasis

Kumud R. Poudel, Minna Roh-Johnson, Allen Su, Thuong Ho, Haritha Mathsyaraja, Sarah Anderson, William M. Grady, Cecilia Moens, Maralice Conacci-Sorrell, Robert N. Eisenman, Jihong Bai

Dev Cell. Author manuscript; available in PMC 2019 Jun 18.

Published in final edited form as: Dev Cell. 2018 Jun 18; 45(6): 738–752.e6. doi: 10.1016/j.devcel.2018.05.021

PMCID:: PMC6095642

Abstract Article PDF–2.4M

Select item 56638785.

The Tiam1 guanine nucleotide exchange factor is auto-inhibited by its pleckstrin homology coiled-coil extension domain

Zhen Xu, Lokesh Gakhar, Fletcher E. Bain, Maria Spies, Ernesto J. Fuentes

J Biol Chem. 2017 Oct 27; 292(43): 17777–17793. Published online 2017 Sep 7. doi: 10.1074/jbc.M117.799114

PMCID:: PMC5663878

Abstract Article PDF–3.6M

Select item 55421866.

TIAM1 variants improve clinical outcome in neuroblastoma

Elena Sanmartín, Yania Yáñez, Victoria Fornés-Ferrer, José L. Zugaza, Adela Cañete, Victoria Castel, Jaime Font de Mora

Oncotarget. 2017 Jul 11; 8(28): 45286–45297. Published online 2017 Apr 3. doi: 10.18632/oncotarget.16787

PMCID:: PMC5542186

Abstract Article PDF–2.6M

Select item 49976747.

Clinicopathological implications of Tiam1 overexpression in invasive ductal carcinoma of the breast

Zhenling Li, Qixiang Liu, Junjie Piao, Fenjian Hua, Jing Wang, Guang Jin, Zhenhua Lin, Yan Zhang

BMC Cancer. 2016; 16(1): 681. Published online 2016 Aug 25. doi: 10.1186/s12885-016-2724-0

PMCID:: PMC4997674

Abstract Article PDF–1.7M

Select item 47300348.

Biological effects of RNAi targeted inhibiting Tiam1 gene expression on cholangiocarcinoma cells

Wei Cheng, Yaling Liu, Zhi Zuo, Xinmin Yin, Bo Jiang, Daojin Chen, Chuang Peng, Jianhui Yang

Int J Clin Exp Pathol. 2015; 8(12): 15511–15526. Published online 2015 Dec 1.

PMCID:: PMC4730034

Abstract Article PDF–1.2M

Select item 42507439.

Tiam1 gene expression and its significance in colorectal carcinoma

Li Liu, De-Hua Wu, Yan-Qing Ding

World J Gastroenterol. 2005 Feb 7; 11(5): 705–707. Published online 2005 Feb 7. doi: 10.3748/wjg.v11.i5.705

PMCID:: PMC4250743

Abstract Article PDF–282K

Select item 397361610.

Expression of Tiam1 predicts lymph node metastasis and poor survival of lung adenocarcinoma patients

Shuguang Liu, Yumei Li, Wenjuan Qi, Yunfei Zhao, Aili Huang, Wenjie Sheng, Bin Lei, Peixin Lin, Haili Zhu, Wenxia Li, Hong Shen

Diagn Pathol. 2014; 9: 69. Published online 2014 Mar 24. doi: 10.1186/1746-1596-9-69

PMCID:: PMC3973616

Abstract Article PDF–1.2M

Select item 385997311.

EphA2 signalling following endocytosis: role of Tiam1

Pomme Boissier, Jin Chen, Uyen Huynh-Do

Traffic. Author manuscript; available in PMC 2014 Dec 1.

Published in final edited form as: Traffic. 2013 Dec; 14(12): 10.1111/tra.12123. Published online 2013 Oct 10. doi: 10.1111/tra.12123

PMCID:: PMC3859973

Abstract Article PDF–6.3M

Select item 373737312.

RNAi Mediated Tiam1 Gene Knockdown Inhibits Invasion of Retinoblastoma

Nithya Subramanian, Saranya Navaneethakrishnan, Jyotirmay Biswas, Rupinder K. Kanwar, Jagat R. Kanwar, Subramanian Krishnakumar

PLoS One. 2013; 8(8): e70422. Published online 2013 Aug 7. doi: 10.1371/journal.pone.0070422

Expression of Concern in:: PLoS One. 2021; 16(5): e0252495.

PMCID:: PMC3737373

Abstract Article PDF–4.6M

Select item 309695613.

Regulation of breast cancer cell motility by T-cell lymphoma invasion and metastasis-inducing protein

Homer C Adams, III, Ru Chen, Zhuoming Liu, Ian P Whitehead

Breast Cancer Res. 2010; 12(5): R69. Published online 2010 Sep 6. doi: 10.1186/bcr2637

PMCID:: PMC3096956

Abstract Article PDF–2.0M

Select item 299794114.

The role of fibroblast Tiam1 in tumor cell invasion and metastasis

Kun Xu, Soumitra Rajagopal, Ina Klebba, Shumin Dong, Yuxin Ji, Jiewei Liu, Charlotte Kuperwasser, Jonathan A. Garlick, Stephen P. Naber, Rachel J. Buchsbaum

Oncogene. Author manuscript; available in PMC 2011 Jun 16.

Published in final edited form as: Oncogene. 2010 Dec 16; 29(50): 6533–6542. Published online 2010 Aug 30. doi: 10.1038/onc.2010.385

PMCID:: PMC2997941

Abstract Article PDF–656K

Select item 289831615.

miR-10b Targets Tiam1: IMPLICATIONS FOR Rac ACTIVATION AND CARCINOMA MIGRATION

Charlotte H. Moriarty, Bryan Pursell, Arthur M. Mercurio

J Biol Chem. 2010 Jul 2; 285(27): 20541–20546. Published online 2010 May 5. doi: 10.1074/jbc.M110.121012

PMCID:: PMC2898316

Abstract Article PDF–1.0M

Select item 236070316.

Prognostic relevance of Tiam1 protein expression in prostate carcinomas

R Engers, M Mueller, A Walter, J G Collard, R Willers, H E Gabbert

Br J Cancer. 2006 Oct 23; 95(8): 1081–1086. Published online 2006 Sep 26. doi: 10.1038/sj.bjc.6603385

PMCID:: PMC2360703

Abstract Article PDF–204K

Select item 113396117.

Inositol phospholipids regulate the guanine-nucleotide-exchange factor Tiam1 by facilitating its binding to the plasma membrane and regulating GDP/GTP exchange on Rac1

Ian N. Fleming, Ian H. Batty, Alan R. Prescott, Alex Gray, Gursant S. Kular, Hazel Stewart, C. Peter Downes

Biochem J. 2004 Sep 15; 382(Pt 3): 857–865. Prepublished online 2004 Jul 9. Published online 2004 Sep 7. doi: 10.1042/BJ20040916

PMCID:: PMC1133961

Abstract Article PDF–538K

Select item 1055659318.

A TIAM1-TRIM28 complex mediates epigenetic silencing of protocadherins to promote migration of lung cancer cells

Lucy Ginn, Joe Maltas, Martin J. Baker, Anshuman Chaturvedi, Leah Wilson, Ryan Guilbert, Fabio M. R. Amaral, Lynsey Priest, Holly Mole, Fiona Blackhall, Zoi Diamantopoulou, Tim C. P. Somervaille, Adam Hurlstone, Angeliki Malliri

Proc Natl Acad Sci U S A. 2023 Oct 3; 120(40): e2300489120. Published online 2023 Sep 25. doi: 10.1073/pnas.2300489120

PMCID:: PMC10556593

Abstract Article PDF–6.6M

Select item 859564219.

TIAM1-RAC1 promote small-cell lung cancer cell survival through antagonizing Nur77-induced BCL2 conformational change

Aishwarya Payapilly, Ryan Guilbert, Tine Descamps, Gavin White, Peter Magee, Cong Zhou, Alastair Kerr, Kathryn L. Simpson, Fiona Blackhall, Caroline Dive, Angeliki Malliri

Cell Rep. 2021 Nov 9; 37(6): 109979. Published online 2021 Nov 9. doi: 10.1016/j.celrep.2021.109979