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Items: 1 to 20 of 25

1.
An RNF168 fragment defective for focal accumulation at DNA damage is proficient for inhibition of homologous recombination in BRCA1 deficient cells
Meilen C. Muñoz, Diana A. Yanez, Jeremy M. Stark
Nucleic Acids Res. 2014 Aug 1; 42(12): 7720–7733. Published online 2014 May 14. doi: 10.1093/nar/gku421
PMCID:
PMC4081061
AbstractArticlePDF–2.0M
2.
RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors
Parasvi S. Patel, Karan Joshua Abraham, Kiran Kumar Naidu Guturi, Marie-Jo Halaby, Zahra Khan, Luis Palomero, Brandon Ho, Shili Duan, Jonathan St-Germain, Arash Algouneh, Francesca Mateo, Samah El Ghamrasni, Haithem Barbour, Daniel R. Barnes, Jonathan Beesley, Otto Sanchez, Hal K. Berman, Grant W. Brown, El Bachir Affar, Georgia Chenevix-Trench, Antonis C. Antoniou, Cheryl H. Arrowsmith, Brian Raught, Miquel Angel Pujana, Karim Mekhail, Anne Hakem, Razqallah Hakem
J Clin Invest. 2021 Feb 1; 131(3): e140105. Published online 2021 Feb 1. doi: 10.1172/JCI140105
PMCID:
PMC7843228
AbstractArticlePDF–8.1M
3.
RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks
Miyuki Bohgaki, Toshiyuki Bohgaki, Samah El Ghamrasni, Tharan Srikumar, Georges Maire, Stephanie Panier, Amélie Fradet-Turcotte, Grant S. Stewart, Brian Raught, Anne Hakem, Razqallah Hakem
Proc Natl Acad Sci U S A. 2013 Dec 24; 110(52): 20982–20987. Published online 2013 Dec 9. doi: 10.1073/pnas.1320302111
PMCID:
PMC3876264
AbstractArticlePDF–912K
4.
A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure
Martijn S Luijsterburg, Klara Acs, Leena Ackermann, Wouter W Wiegant, Simon Bekker-Jensen, Dorthe H Larsen, Kum Kum Khanna, Haico van Attikum, Niels Mailand, Nico P Dantuma
EMBO J. 2012 May 30; 31(11): 2511–2527. Published online 2012 Apr 24. doi: 10.1038/emboj.2012.104
PMCID:
PMC3365417
AbstractArticlePDF–3.6M
5.
Genomic Instability, Defective Spermatogenesis, Immunodeficiency, and Cancer in a Mouse Model of the RIDDLE Syndrome
Toshiyuki Bohgaki, Miyuki Bohgaki, Renato Cardoso, Stephanie Panier, Dimphy Zeegers, Li Li, Grant S. Stewart, Otto Sanchez, M. Prakash Hande, Daniel Durocher, Anne Hakem, Razqallah Hakem
PLoS Genet. 2011 Apr; 7(4): e1001381. Published online 2011 Apr 28. doi: 10.1371/journal.pgen.1001381
PMCID:
PMC3084200
AbstractArticlePDF–4.7M
6.
Degradation of Ubiquitin-Editing Enzyme A20 following Autophagy Activation Promotes RNF168 Nuclear Translocation and NF-κB Activation in Lupus Nephritis
Luxi Zou, Ling Sun, Ruixue Hua, Yu Wu, Linlin Sun, Ting Chen
J Innate Immun. 2023 Jan-Dec; 15(1): 428–441. Published online 2023 Mar 21. doi: 10.1159/000527624
PMCID:
PMC10090963
AbstractArticlePDF–1.4M
7.
The mTOR-S6K Pathway Links Growth Signaling to DNA Damage Response by Targeting RNF168
Xiaoduo Xie, Hongli Hu, Xinyuan Tong, Long Li, Xiangyuan Liu, Min Chen, Huairui Yuan, Xia Xie, Qingrun Li, Yuxue Zhang, Huafang Ouyang, Mengqi Wei, Jing Huang, Pengda Liu, Wenjian Gan, Yong Liu, Anyong Xie, Xiaoling Kuai, Gung-Wei Chirn, Hu Zhou, Rong Zeng, Ronggui Hu, Jun Qin, Fei-Long Meng, Wenyi Wei, Hongbin Ji, Daming Gao
Nat Cell Biol. Author manuscript; available in PMC 2018 Aug 5.
Published in final edited form as: Nat Cell Biol. 2018 Mar; 20(3): 320–331. Published online 2018 Feb 5. doi: 10.1038/s41556-017-0033-8
PMCID:
PMC5826806
AbstractArticlePDF–2.8M
8.
RNF168 forms a functional complex with RAD6 during the DNA damage response
Chao Liu, Degui Wang, Jiaxue Wu, Jennifer Keller, Teng Ma, Xiaochun Yu
J Cell Sci. 2013 May 1; 126(9): 2042–2051. doi: 10.1242/jcs.122945
PMCID:
PMC3666256
AbstractArticle
9.
The RNF8/RNF168 ubiquitin ligase cascade facilitates class switch recombination
Shaliny Ramachandran, Richard Chahwan, Rajeev M. Nepal, Darina Frieder, Stephanie Panier, Sergio Roa, Ahmad Zaheen, Daniel Durocher, Matthew D. Scharff, Alberto Martin
Proc Natl Acad Sci U S A. 2010 Jan 12; 107(2): 809–814. Published online 2009 Dec 22. doi: 10.1073/pnas.0913790107
PMCID:
PMC2818930
AbstractArticlePDF–556K
10.
A PALB2-interacting domain in RNF168 couples homologous recombination to DNA break-induced chromatin ubiquitylation
Martijn S Luijsterburg, Dimitris Typas, Marie-Christine Caron, Wouter W Wiegant, Diana van den Heuvel, Rick A Boonen, Anthony M Couturier, Leon H Mullenders, Jean-Yves Masson, Haico van Attikum
eLife. 2017; 6: e20922. Published online 2017 Feb 27. doi: 10.7554/eLife.20922
PMCID:
PMC5328590
AbstractArticlePDF–4.1M
11.
BRCA1 haploinsufficiency is masked by RNF168-mediated chromatin ubiquitylation
Dali Zong, Salomé Adam, Yifan Wang, Hiroyuki Sasanuma, Elsa Callén, Matilde Murga, Amanda Day, Michael J. Kruhlak, Nancy Wong, Meagan Munro, Arnab Ray Chaudhuri, Baktiar Karim, Bing Xia, Shunichi Takeda, Neil Johnson, Daniel Durocher, André Nussenzweig
Mol Cell. Author manuscript; available in PMC 2020 Mar 21.
Published in final edited form as: Mol Cell. 2019 Mar 21; 73(6): 1267–1281.e7. Published online 2019 Jan 28. doi: 10.1016/j.molcel.2018.12.010
PMCID:
PMC6430682
AbstractArticlePDF–2.3M
12.
Behavioral changes and growth deficits in a CRISPR engineered mouse model of the schizophrenia-associated 3q29 deletion
Timothy P. Rutkowski, Ryan H. Purcell, Rebecca M. Pollak, Stephanie M. Grewenow, Georgette M. Gafford, Tamika Malone, Uswa A. Khan, Jason P. Schroeder, Michael P. Epstein, Gary J. Bassell, Stephen T. Warren, David Weinshenker, Tamara Caspary, Jennifer Gladys Mulle
Mol Psychiatry. 2021; 26(3): 772–783. Published online 2019 Apr 11. doi: 10.1038/s41380-019-0413-5
PMCID:
PMC6788962
AbstractArticlePDF–1.8M
13.
RNF168 and USP10 regulate topoisomerase IIα function via opposing effects on its ubiquitylation
Kiran Kumar Naidu Guturi, Miyuki Bohgaki, Toshiyuki Bohgaki, Tharan Srikumar, Deborah Ng, Ramya Kumareswaran, Samah El Ghamrasni, Justin Jeon, Parasvi Patel, Mohamed Saad Eldin, Rob Bristow, Peter Cheung, Grant S. Stewart, Brian Raught, Anne Hakem, Razqallah Hakem
Nat Commun. 2016; 7: 12638. Published online 2016 Aug 25. doi: 10.1038/ncomms12638
PMCID:
PMC5007378
AbstractArticlePDF–1.7M
14.
The histone demethylase LSD1/KDM1A promotes the DNA damage response
Nima Mosammaparast, Haeyoung Kim, Benoit Laurent, Yu Zhao, Hui Jun Lim, Mona C. Majid, Sebastian Dango, Yuying Luo, Kristina Hempel, Mathew E. Sowa, Steven P. Gygi, Hanno Steen, J. Wade Harper, Bruce Yankner, Yang Shi
J Cell Biol. 2013 Nov 11; 203(3): 457–470. doi: 10.1083/jcb.201302092
PMCID:
PMC3824007
AbstractArticlePDF–2.6M
15.
JMJD1C Exhibits Multiple Functions in Epigenetic Regulation during Spermatogenesis
Ryusuke Nakajima, Hideyuki Okano, Toshiaki Noce
PLoS One. 2016; 11(9): e0163466. Published online 2016 Sep 20. doi: 10.1371/journal.pone.0163466
PMCID:
PMC5029890
AbstractArticlePDF–4.6M
16.
Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray
Tetsuya S. Tanaka, Saied A. Jaradat, Meng K. Lim, George J. Kargul, Xiaohong Wang, Marija J. Grahovac, Serafino Pantano, Yuri Sano, Yulan Piao, Ramaiah Nagaraja, Hirofumi Doi, William H. Wood, III, Kevin G. Becker, Minoru S. H. Ko
Proc Natl Acad Sci U S A. 2000 Aug 1; 97(16): 9127–9132. doi: 10.1073/pnas.97.16.9127
PMCID:
PMC16833
AbstractArticlePDF–847K
17.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
18.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
19.
Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention
Brian P. Zambrowicz, Alejandro Abuin, Ramiro Ramirez-Solis, Lizabeth J. Richter, James Piggott, Hector BeltrandelRio, Eric C. Buxton, Joel Edwards, Rick A. Finch, Carl J. Friddle, Anupma Gupta, Gwenn Hansen, Yi Hu, Wenhu Huang, Crystal Jaing, Billie Wayne Key, Jr., Peter Kipp, Buckley Kohlhauff, Zhi-Qing Ma, Diane Markesich, Robert Payne, David G. Potter, Ny Qian, Joseph Shaw, Jeff Schrick, Zheng-Zheng Shi, Mary Jean Sparks, Isaac Van Sligtenhorst, Peter Vogel, Wade Walke, Nianhua Xu, Qichao Zhu, Christophe Person, Arthur T. Sands
Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24): 14109–14114. Published online 2003 Nov 10. doi: 10.1073/pnas.2336103100
Correction in:
Proc Natl Acad Sci U S A. 2004 Mar 23; 101(12): 4332.
PMCID:
PMC283554
AbstractArticlePDF–481K
20.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M

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