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Select item 80888371.

Blockade of Repulsive guidance molecule b (RGMb) inhibits allergen-induced airways disease

Sanhong Yu, Krystle M. Leung, Hye-Young Kim, Sarah E. Umetsu, Yanping Xiao, Lee A. Albacker, Hyun-Jun Lee, Dale T. Umetsu, Gordon J. Freeman, Rosemarie H. DeKruyff

J Allergy Clin Immunol. Author manuscript; available in PMC 2021 May 2.

Published in final edited form as: J Allergy Clin Immunol. 2019 Jul; 144(1): 94–108.e11. Published online 2019 Jan 29. doi: 10.1016/j.jaci.2018.12.1022

PMCID:: PMC8088837

Abstract Article PDF–3.7M

Select item 58161822.

RGMb protects against acute kidney injury by inhibiting tubular cell necroptosis via an MLKL-dependent mechanism

Wenjing Liu, Binbin Chen, Yang Wang, Chenling Meng, Huihui Huang, Xiao-Ru Huang, Jinzhong Qin, Shrikant R. Mulay, Hans-Joachim Anders, Andong Qiu, Baoxue Yang, Gordon J. Freeman, Hua Jenny Lu, Herbert Y. Lin, Zhi-Hua Zheng, Hui-Yao Lan, Yu Huang, Yin Xia

Proc Natl Acad Sci U S A. 2018 Feb 13; 115(7): E1475–E1484. Published online 2018 Jan 30. doi: 10.1073/pnas.1716959115

PMCID:: PMC5816182

Abstract Article PDF–2.2M

Select item 41016373.

Distinct mechanisms of induction of hepatic growth hormone resistance by endogenous IL-6, TNF-α, and IL-1β

Yueshui Zhao, Xiaoqiu Xiao, Stuart J. Frank, Herbert Y. Lin, Yin Xia

Am J Physiol Endocrinol Metab. 2014 Jul 15; 307(2): E186–E198. Published online 2014 Jun 3. doi: 10.1152/ajpendo.00652.2013

PMCID:: PMC4101637

Abstract Article

Select item 38147494.

Dragon (Repulsive Guidance Molecule RGMb) Inhibits E-cadherin Expression and Induces Apoptosis in Renal Tubular Epithelial Cells

Wenjing Liu, Xiaoling Li, Yueshui Zhao, Xiao-Ming Meng, Chao Wan, Baoxue Yang, Hui-Yao Lan, Herbert Y. Lin, Yin Xia

J Biol Chem. 2013 Nov 1; 288(44): 31528–31539. Published online 2013 Sep 19. doi: 10.1074/jbc.M113.517573

PMCID:: PMC3814749

Abstract Article PDF–2.4M

Select item 32439475.

The BMP Coreceptor RGMb Promotes While the Endogenous BMP Antagonist Noggin Reduces Neurite Outgrowth and Peripheral Nerve Regeneration by Modulating BMP Signaling

Chi H. E. Ma, Gary J. Brenner, Takao Omura, Omar A. Samad, Michael Costigan, Perrine Inquimbert, Vera Niederkofler, Rishard Salie, Chia Chi Sun, Herbert Y. Lin, Silvia Arber, Giovanni Coppola, Clifford J. Woolf, Tarek A. Samad

J Neurosci. 2011 Dec 14; 31(50): 18391–18400. doi: 10.1523/JNEUROSCI.4550-11.2011

PMCID:: PMC3243947

Abstract Article PDF–2.7M

Select item 13513036.

Localization and action of Dragon (RGMb), a novel BMP co-receptor, throughout the reproductive axis.

Yin Xia, Yisrael Sidis, Abir Mukherjee, Tarek A. Samad, Gary Brenner, Clifford J. Woolf, Herbert Y. Lin, Alan Schneyer

Endocrinology. Author manuscript; available in PMC 2006 Jan 26.

Published in final edited form as: Endocrinology. 2005 Aug; 146(8): 3614–3621. Published online 2005 May 12. doi: 10.1210/en.2004-1676

PMCID:: PMC1351303

Abstract Article PDF–1.3M

Select item 62075677.

B7-DC (PD-L2) costimulation of CD4⁺ T-helper 1 response via RGMb

Xinxin Nie, Wenni Chen, Ying Zhu, Baozhu Huang, Weiwei Yu, Zhanshuai Wu, Sizheng Guo, Yiping Zhu, Liqun Luo, Shengdian Wang, Lieping Chen

Cell Mol Immunol. 2018 Oct; 15(10): 888–897. Published online 2017 May 8. doi: 10.1038/cmi.2017.17

PMCID:: PMC6207567

Abstract Article PDF–4.2M

Select item 46530248.

Dragon (repulsive guidance molecule b, RGMb) is a novel gene that promotes colorectal cancer growth

Ying Shi, Guo-Bin Chen, Xiao-Xiao Huang, Chuan-Xing Xiao, Huan-Huan Wang, Ye-Sen Li, Jin-Fang Zhang, Shao Li, Yin Xia, Jian-Lin Ren, Bayasi Guleng

Oncotarget. 2015 Aug 21; 6(24): 20540–20554. Published online 2015 May 12. doi: 10.18632/oncotarget.4110

PMCID:: PMC4653024

Abstract Article PDF–5.6M

Select item 40109019.

RGMb is a novel binding partner for PD-L2 and its engagement with PD-L2 promotes respiratory tolerance

Yanping Xiao, Sanhong Yu, Baogong Zhu, Denis Bedoret, Xia Bu, Loise M. Francisco, Ping Hua, Jonathan S. Duke-Cohan, Dale T. Umetsu, Arlene H. Sharpe, Rosemarie H. DeKruyff, Gordon J. Freeman

J Exp Med. 2014 May 5; 211(5): 943–959. doi: 10.1084/jem.20130790

PMCID:: PMC4010901

Abstract Article PDF–3.9M

Select item 806308810.

Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling

Ross A. Robinson, Samuel C. Griffiths, Lieke L. van de Haar, Tomas Malinauskas, Eljo Y. van Battum, Pavol Zelina, Rebekka A. Schwab, Dimple Karia, Lina Malinauskaite, Sara Brignani, Marleen H. van den Munkhof, Özge Düdükcü, Anna A. De Ruiter, Dianne M.A. Van den Heuvel, Benjamin Bishop, Jonathan Elegheert, A. Radu Aricescu, R. Jeroen Pasterkamp, Christian Siebold

Cell. 2021 Apr 15; 184(8): 2103–2120.e31. doi: 10.1016/j.cell.2021.02.045

PMCID:: PMC8063088

Abstract Article

Select item 672981711.

Repulsive Guidance Molecule (RGM) Gene Function Is Required for Neural Tube Closure But Not Retinal Topography in the Mouse Visual System

Vera Niederkofler, Rishard Salie, Markus Sigrist, Silvia Arber

J Neurosci. 2004 Jan 28; 24(4): 808–818. doi: 10.1523/JNEUROSCI.4610-03.2004

PMCID:: PMC6729817

Abstract Article PDF–1.4M

Select item 357302712.

Spatiotemporal Expression of Repulsive Guidance Molecules (RGMs) and Their Receptor Neogenin in the Mouse Brain

Dianne M. A. van den Heuvel, Anita J. C. G. M. Hellemons, R. Jeroen Pasterkamp

PLoS One. 2013; 8(2): e55828. Published online 2013 Feb 14. doi: 10.1371/journal.pone.0055828

PMCID:: PMC3573027

Abstract Article PDF–8.6M

Select item 673038513.

DRAGON: A Member of the Repulsive Guidance Molecule-Related Family of Neuronal- and Muscle-Expressed Membrane Proteins Is Regulated by DRG11 and Has Neuronal Adhesive Properties

Tarek A. Samad, Ashok Srinivasan, Laurie A. Karchewski, Sung-Jin Jeong, Jason A. Campagna, Ru-Rong Ji, David A. Fabrizio, Ying Zhang, Herbert Y. Lin, Esther Bell, Clifford J. Woolf

J Neurosci. 2004 Feb 25; 24(8): 2027–2036. doi: 10.1523/JNEUROSCI.4115-03.2004

PMCID:: PMC6730385

Abstract Article PDF–873K

Select item 364898214.

Foxg1 Coordinates the Switch from Non-Radially to Radially Migrating Glutamatergic Subtypes in the Neocortex through Spatiotemporal Repression

Takuma Kumamoto, Ken-ichi Toma, Gunadi, Will McKenna, Takeya Kasukawa, Sol Katzman, Bin Chen, Carina Hanashima

Cell Rep. Author manuscript; available in PMC 2013 May 9.

Published in final edited form as: Cell Rep. 2013 Mar 28; 3(3): 931–945. Published online 2013 Mar 21. doi: 10.1016/j.celrep.2013.02.023

PMCID:: PMC3648982

Abstract Article PDF–6.2M

Select item 367058515.

Dragon (RGMb) inhibits interleukin (IL)-6 expression in macrophages

Yin Xia, Virna Cortez-Retamozo, Vera Niederkofler, Rishard Salie, Shanzhuo Chen, Tarek Samad, Charles C. Hong, Silvia Arber, Jatin M. Vyas, Ralph Weissleder, Mikael J. Pittet, Herbert Y. Lin

J Immunol. Author manuscript; available in PMC 2013 Jun 3.

Published in final edited form as: J Immunol. 2011 Feb 1; 186(3): 1369–1376. Published online 2010 Dec 27. doi: 10.4049/jimmunol.1002047

PMCID:: PMC3670585

Abstract Article PDF–1.5M

Select item 476456516.

Synergistic integration of Netrin and ephrin axon guidance signals by spinal motor neurons

Sebastian Poliak, Daniel Morales, Louis-Philippe Croteau, Dayana Krawchuk, Elena Palmesino, Susan Morton, Jean-François Cloutier, Frederic Charron, Matthew B Dalva, Susan L Ackerman, Tzu-Jen Kao, Artur Kania

eLife. 2015; 4: e10841. Published online 2015 Dec 3. doi: 10.7554/eLife.10841

PMCID:: PMC4764565

Abstract Article PDF–5.0M

Select item 679017717.

Diverse spinal commissural neuron populations revealed by fate mapping and molecular profiling using a novel Robo3^Cre mouse

Alastair J. Tulloch, Shaun Teo, Brigett V. Carvajal, Marc Tessier-Lavigne, Alexander Jaworski

J Comp Neurol. Author manuscript; available in PMC 2020 Dec 15.

Published in final edited form as: J Comp Neurol. 2019 Dec 15; 527(18): 2948–2972. Published online 2019 Jun 14. doi: 10.1002/cne.24720

PMCID:: PMC6790177

Abstract Article PDF–3.4M

Select item 583337318.

Temporal requirements for ISL1 in sympathetic neuron proliferation, differentiation, and diversification

Qingquan Zhang, Ru Huang, Youqiong Ye, Xiaoxia Guo, Jun Lu, Fugui Zhu, Xiaohui Gong, Qitong Zhang, Jie Yan, Lina Luo, Shaowei Zhuang, Yihan Chen, Xiaodong Zhao, Sylvia M. Evans, Cizhong Jiang, Xingqun Liang, Yunfu Sun

Cell Death Dis. 2018 Feb; 9(2): 247. Published online 2018 Feb 14. doi: 10.1038/s41419-018-0283-9

PMCID:: PMC5833373

Abstract Article PDF–4.6M

Select item 831323919.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 141356820.

BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System

Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran

PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086