PMC Links for Gene (Select 6711) - PMC

Links from Gene

Items: 1 to 20 of 184

<< First< Prev

Page of 10

Select item 111823761.

Heterozygous Variants in SPTBN1 Cause Intellectual Disability and Autism

Jill A. Rosenfeld, Rui Xiao, Mir Reza Bekheirnia, Farah Kanani, Michael J. Parker, Mary K. Koenig, Arie van Haeringen, Claudia Ruivenkamp, Joana Rosmaninho-Salgado, Pedro M. Almeida, Joaquim Sá, Jorge Pinto Basto, Emily Palen, Kathryn F. Oetjens, Lindsay C. Burrage, Fan Xia, Pengfei Liu, Christine M. Eng, Undiagnosed Diseases Network, Yaping Yang, Jennifer E. Posey, Brendan H. Lee

Am J Med Genet A. Author manuscript; available in PMC 2024 Jun 17.

Published in final edited form as: Am J Med Genet A. 2021 Jul; 185(7): 2037–2045. Published online 2021 Apr 13. doi: 10.1002/ajmg.a.62201

PMCID:: PMC11182376

Abstract Article PDF–779K

Select item 100717452.

Clinical significance of nonerythrocytic spectrin Beta 1 (SPTBN1) in human kidney renal clear cell carcinoma and uveal melanoma: a study based on Pan-Cancer Analysis

Wenting Tang, Qiong Shao, Zhanwen He, Xu Zhang, Xiaojuan Li, Ruohao Wu

BMC Cancer. 2023; 23: 303. Published online 2023 Apr 3. doi: 10.1186/s12885-023-10789-3

PMCID:: PMC10071745

Abstract Article PDF–6.8M

Select item 77570253.

βII spectrin (SPTBN1): biological function and clinical potential in cancer and other diseases

Panyu Yang, Yanyan Yang, Pin Sun, Yu Tian, Fang Gao, Chen Wang, Tingyu Zong, Min Li, Ying Zhang, Tao Yu, Zhirong Jiang

Int J Biol Sci. 2021; 17(1): 32–49. Published online 2021 Jan 1. doi: 10.7150/ijbs.52375

PMCID:: PMC7757025

Abstract Article PDF–2.1M

Select item 58592914.

β2 spectrin-mediated differentiation repressed the properties of liver cancer stem cells through β-catenin

Yuhua Chen, Lingling Meng, Haitao Shang, Qian Dou, Zhiwen Lu, Liping Liu, Zhijun Wang, Xingxing He, Yuhu Song

Cell Death Dis. 2018 Apr; 9(4): 424. Published online 2018 Mar 19. doi: 10.1038/s41419-018-0456-6

PMCID:: PMC5859291

Abstract Article PDF–3.3M

Select item 42112685.

Disruption of transforming growth factor-β signaling through β-spectrin ELF leads to hepatocellular cancer through cyclin D1 activation

K Kitisin, N Ganesan, Y Tang, W Jogunoori, EA Volpe, SS Kim, V Katuri, B Kallakury, M Pishvaian, C Albanese, J Mendelson, M Zasloff, A Rashid, T Fishbein, SRT Evans, A Sidawy, EP Reddy, B Mishra, LB Johnson, K Shetty, L Mishra

Oncogene. Author manuscript; available in PMC 2014 Oct 28.

Published in final edited form as: Oncogene. 2007 Nov 1; 26(50): 7103–7110. Published online 2007 Jun 4. doi: 10.1038/sj.onc.1210513

PMCID:: PMC4211268

Abstract Article PDF–2.4M

Select item 107070546.

SPTBN1 Mediates the Cytoplasmic Constraint of PTTG1, Impairing Its Oncogenic Activity in Human Seminoma

Emanuela Teveroni, Fiorella Di Nicuolo, Edoardo Vergani, Alessandro Oliva, Emanuele Pierpaolo Vodola, Giada Bianchetti, Giuseppe Maulucci, Marco De Spirito, Tonia Cenci, Francesco Pierconti, Gaetano Gulino, Federica Iavarone, Andrea Urbani, Domenico Milardi, Alfredo Pontecorvi, Francesca Mancini

Int J Mol Sci. 2023 Dec; 24(23): 16891. Published online 2023 Nov 29. doi: 10.3390/ijms242316891

PMCID:: PMC10707054

Abstract Article PDF–2.9M

Select item 97564797.

SPTBN1 abrogates renal clear cell carcinoma progression via glycolysis reprogramming in a GPT2-dependent manner

Jiajin Wu, Chenkui Miao, Yuhao Wang, Songbo Wang, Zhongyuan Wang, Yiyang Liu, Xiaoyi Wang, Zengjun Wang

J Transl Med. 2022; 20: 603. Published online 2022 Dec 16. doi: 10.1186/s12967-022-03805-w

PMCID:: PMC9756479

Abstract Article PDF–5.4M

Select item 96672018.

SPTBN1 attenuates rheumatoid arthritis synovial cell proliferation, invasion, migration and inflammatory response by binding to PIK3R2

Li‐ping Dai, Xiao‐dong Xu, Ting‐ting Yang, Zhi‐hua Yin, Zhi‐zhong Ye, Ya‐zhi Wei

Immun Inflamm Dis. 2022 Dec; 10(12): e724. Published online 2022 Nov 16. doi: 10.1002/iid3.724

PMCID:: PMC9667201

Abstract Article PDF–3.6M

Select item 73460399.

SPTBN1 suppresses the progression of epithelial ovarian cancer via SOCS3-mediated blockade of the JAK/STAT3 signaling pathway

Mo Chen, Jia Zeng, Shuyi Chen, Jiajia Li, Huijie Wu, Xuhui Dong, Yuan Lei, Xiuling Zhi, Liangqing Yao

Aging (Albany NY) 2020 Jun 15; 12(11): 10896–10911. Published online 2020 Jun 8. doi: 10.18632/aging.103303

PMCID:: PMC7346039

Abstract Article PDF–2.0M

Select item 435958610.

The prognostic value of combined TGF-β1 and ELF in hepatocellular carcinoma

Fei Ji, Shun-Jun Fu, Shun-Li Shen, Long-Juan Zhang, Qing-Hua Cao, Shao-Qiang Li, Bao-Gang Peng, Li-Jian Liang, Yun-Peng Hua

BMC Cancer. 2015; 15: 116. Published online 2015 Mar 11. doi: 10.1186/s12885-015-1127-y

PMCID:: PMC4359586

Abstract Article PDF–807K

Select item 432799011.

βII-spectrin (SPTBN1) Suppresses Progression of Hepatocellular Carcinoma and Wnt Signaling via Regulation of Wnt Inhibitor Kallistatin

Xiuling Zhi, Ling Lin, Shaoxian Yang, Krithika Bhuvaneshwar, Hongkun Wang, Yuriy Gusev, Mi-Hye Lee, Bhaskar Kallakury, Narayan Shivapurkar, Katherine Cahn, Xuefei Tian, John L. Marshall, Stephen W. Byers, Aiwu R. He

Hepatology. Author manuscript; available in PMC 2016 Feb 1.

Published in final edited form as: Hepatology. 2015 Feb; 61(2): 598–612. doi: 10.1002/hep.27558

PMCID:: PMC4327990

Abstract Article PDF–2.1M

Select item 297523312.

Epigenetic Silencing of β-Spectrin, a TGF-β Signaling/Scaffolding Protein in a Human Cancer Stem Cell Disorder: BECKWITH-WIEDEMANN SYNDROME

Zhi-Xing Yao, Wilma Jogunoori, Sanaa Choufani, Asif Rashid, Tiffany Blake, Wenguo Yao, Peter Kreishman, Rupen Amin, Anton A. Sidawy, Stephen R. T. Evans, Milton Finegold, E. Premkumar Reddy, Bibhuti Mishra, Rosanna Weksberg, Rakesh Kumar, Lopa Mishra

J Biol Chem. 2010 Nov 12; 285(46): 36112–36120. Published online 2010 Aug 25. doi: 10.1074/jbc.M110.162347

PMCID:: PMC2975233

Abstract Article PDF–3.5M

Select item 221170413.

Conformational change of erythroid α-spectrin at the tetramerization site upon binding β-spectrin

Fei Long, Dan McElheny, Shaokai Jiang, Sunghyouk Park, Michael S. Caffrey, Leslie W.-M. Fung

Protein Sci. 2007 Nov; 16(11): 2519–2530. doi: 10.1110/ps.073115307

PMCID:: PMC2211704

Abstract Article PDF–683K

Select item 122210614.

Binding of the merlin-I product of the neurofibromatosis type 2 tumour suppressor gene to a novel site in beta-fodrin is regulated by association between merlin domains.

G W Neill, M R Crompton

Biochem J. 2001 Sep 15; 358(Pt 3): 727–735. doi: 10.1042/0264-6021:3580727

PMCID:: PMC1222106

Summary PDF–218K

Select item 1105797415.

Identification of bone mineral density associated genes with shared genetic architectures across multiple tissues: Functional insights for EPDR1, PKDCC, and SPTBN1

Jongyun Jung, Qing Wu

PLoS One. 2024; 19(4): e0300535. Published online 2024 Apr 29. doi: 10.1371/journal.pone.0300535

PMCID:: PMC11057974

Abstract Article PDF–1.8M

Select item 827314916.

Pathogenic SPTBN1 variants cause an autosomal dominant neurodevelopmental syndrome

Margot A. Cousin, Blake A. Creighton, Keith A. Breau, Rebecca C. Spillmann, Erin Torti, Sruthi Dontu, Swarnendu Tripathi, Deepa Ajit, Reginald J. Edwards, Simone Afriyie, Julia C. Bay, Kathryn M. Harper, Alvaro A. Beltran, Lorena J. Munoz, Liset Falcon Rodriguez, Michael C. Stankewich, Richard E. Person, Yue Si, Elizabeth A. Normand, Amy Blevins, Alison S. May, Louise Bier, Vimla Aggarwal, Grazia M. S. Mancini, Marjon A. van Slegtenhorst, Kirsten Cremer, Jessica Becker, Hartmut Engels, Stefan Aretz, Jennifer J. MacKenzie, Eva Brilstra, Koen L. I. van Gassen, Richard H. van Jaarsveld, Renske Oegema, Gretchen M. Parsons, Paul Mark, Ingo Helbig, Sarah E. McKeown, Robert Stratton, Benjamin Cogne, Bertrand Isidor, Pilar Cacheiro, Damian Smedley, Helen V. Firth, Tatjana Bierhals, Katja Kloth, Deike Weiss, Cecilia Fairley, Joseph T. Shieh, Amy Kritzer, Parul Jayakar, Evangeline Kurtz-Nelson, Raphael A. Bernier, Tianyun Wang, Evan E. Eichler, Ingrid M. B. H. van de Laar, Allyn McConkie-Rosell, Marie T. McDonald, Jennifer Kemppainen, Brendan C. Lanpher, Laura E. Schultz-Rogers, Lauren B. Gunderson, Pavel N. Pichurin, Grace Yoon, Michael Zech, Robert Jech, Juliane Winkelmann, Undiagnosed Diseases Network, Genomics England Research Consortium, Adriana S. Beltran, Michael T. Zimmermann, Brenda Temple, Sheryl S. Moy, Eric W. Klee, Queenie K.-G. Tan, Damaris N. Lorenzo

Nat Genet. Author manuscript; available in PMC 2022 Jan 1.

Published in final edited form as: Nat Genet. 2021 Jul; 53(7): 1006–1021. Published online 2021 Jul 1. doi: 10.1038/s41588-021-00886-z

PMCID:: PMC8273149

Abstract Article PDF–8.6M

Select item 434233217.

Dysfunction in the βII Spectrin-Dependent Cytoskeleton Underlies Human Arrhythmia

Sakima A. Smith, Amy C. Sturm, Jerry Curran, Crystal F. Kline, Sean C. Little, Ingrid M. Bonilla, Victor P. Long, Michael Makara, Iuliia Polina, Langston D. Hughes, Tyler R. Webb, Zhiyi Wei, Patrick Wright, Niels Voigt, Deepak Bhakta, Katherine G. Spoonamore, Chuansheng Zhang, Raul Weiss, Philip F. Binkley, Paul M. Janssen, Ahmet Kilic, Robert S. Higgins, Mingzhai Sun, Jianjie Ma, Dobromir Dobrev, Mingjie Zhang, Cynthia A. Carnes, Matteo Vatta, Matthew N. Rasband, Thomas J. Hund, Peter J. Mohler

Circulation. Author manuscript; available in PMC 2016 Feb 24.

Published in final edited form as: Circulation. 2015 Feb 24; 131(8): 695–708. Published online 2015 Jan 28. doi: 10.1161/CIRCULATIONAHA.114.013708

PMCID:: PMC4342332

Abstract Article PDF–4.1M

Select item 360091118.

IL-27 inhibits HIV-1 infection in human macrophages by down-regulating host factor SPTBN1 during monocyte to macrophage differentiation

Lue Dai, Kristy B. Lidie, Qian Chen, Joseph W. Adelsberger, Xin Zheng, DaWei Huang, Jun Yang, Richard A. Lempicki, Tauseef Rehman, Robin L. Dewar, Yanmei Wang, Ronald L. Hornung, Kelsey A. Canizales, Stephen J. Lockett, H. Clifford Lane, Tomozumi Imamichi

J Exp Med. 2013 Mar 11; 210(3): 517–534. doi: 10.1084/jem.20120572

PMCID:: PMC3600911

Abstract Article PDF–3.1M

Select item 213394619.

Centractin (ARP1) associates with spectrin revealing a potential mechanism to link dynactin to intracellular organelles

J Cell Biol. 1996 Dec 2; 135(6): 1815–1829. doi: 10.1083/jcb.135.6.1815

PMCID:: PMC2133946

Summary PDF–4.9M

Select item 497480620.

Lung adenocarcinoma harboring concomitant SPTBN1-ALK fusion, c-Met overexpression, and HER-2 amplification with inherent resistance to crizotinib, chemotherapy, and radiotherapy

Fei-fei Gu, Yong Zhang, Yang-yang Liu, Xiao-hua Hong, Jin-yan Liang, Fan Tong, Jing-song Yang, Li Liu

J Hematol Oncol. 2016; 9: 66. Published online 2016 Aug 5. doi: 10.1186/s13045-016-0296-8

PMCID:: PMC4974806

Abstract Article PDF–970K

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from Gene

Items: 1 to 20 of 184

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity