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Select item 91281871.

Bone morphogenetic protein receptor 1α promotes osteolytic lesion of oral squamous cell carcinoma by SHH‐dependent osteoclastogenesis

Qiao Qiao, Le Xu, Qingxiang Li, Yifei Wang, Han Lu, Ning Zhao, Yinfei Pu, Lin Wang, Yuxing Guo, Chuanbin Guo

Cancer Sci. 2022 May; 113(5): 1639–1651. Published online 2022 Mar 23. doi: 10.1111/cas.15330

PMCID:: PMC9128187

Abstract Article PDF–12M

Select item 67086682.

Variable Features of Juvenile Polyposis Syndrome With Gastric Involvement Among Patients With a Large Genomic Deletion of BMPR1A

Sari Lieberman, Rachel Beeri, Tom Walsh, Menachem Schechter, Dan Keret, Elizabet Half, Suleyman Gulsuner, Ariela Tomer, Harold Jacob, Shlomi Cohen, Lina Basel-Salmon, Mahmud Mansur, Rachel Berger, Lior H. Katz, Eliahu Golomb, Tamar Peretz, Zohar Levy, Inbal Kedar, Mary-Claire King, Ephrat Levy-Lahad, Yael Goldberg

Clin Transl Gastroenterol. 2019 Jul; 10(7): e00054. Published online 2019 Jul 1. doi: 10.14309/ctg.0000000000000054

PMCID:: PMC6708668

Abstract Article PDF–344K

Select item 58190763.

Genetic polymorphisms in bone morphogenetic protein receptor type IA gene predisposes individuals to ossification of the posterior longitudinal ligament of the cervical spine via the smad signaling pathway

Hao Wang, Weitao Jin, Haibin Li

BMC Musculoskelet Disord. 2018; 19: 61. Published online 2018 Feb 20. doi: 10.1186/s12891-018-1966-1

PMCID:: PMC5819076

Abstract Article PDF–1.2M

Select item 47792774.

Enrichment of Adipose-Derived Stromal Cells for BMPR1A Facilitates Enhanced Adipogenesis

Elizabeth R. Zielins, Kevin Paik, Ryan C. Ransom, Elizabeth A. Brett, Charles P. Blackshear, Anna Luan, Graham G. Walmsley, David A. Atashroo, Kshemendra Senarath-Yapa, Arash Momeni, Robert Rennert, Michael Sorkin, Eun Young Seo, Charles K. Chan, Geoffrey C. Gurtner, Michael T. Longaker, Derrick C. Wan

Tissue Eng Part A. 2016 Feb 1; 22(3-4): 214–221. Published online 2016 Jan 27. doi: 10.1089/ten.tea.2015.0278

PMCID:: PMC4779277

Abstract Article PDF–571K

Select item 46732075.

Deletion of the BMP receptor BMPR1a impairs mammary tumor formation and metastasis

Michael W. Pickup, Laura D. Hover, Yan Guo, Agnieszka E. Gorska, Anna Chytil, Sergey V. Novitskiy, Harold L. Moses, Philip Owens

Oncotarget. 2015 Sep 8; 6(26): 22890–22904. Published online 2015 Jun 10. doi: 10.18632/oncotarget.4413

PMCID:: PMC4673207

Abstract Article PDF–14M

Select item 37901576.

Reduced expression of bone morphogenetic protein receptor IA in pancreatic cancer is associated with a poor prognosis

P W Voorneveld, V Stache, R J Jacobs, E Smolders, A I Sitters, A Liesker, K S Korkmaz, S M Lam, N F C C De Miranda, H Morreau, L L Kodach, J C H Hardwick

Br J Cancer. 2013 Oct 1; 109(7): 1805–1812. Published online 2013 Aug 22. doi: 10.1038/bjc.2013.486

PMCID:: PMC3790157

Abstract Article PDF–355K

Select item 36831097.

BMPR1A Mutations in Juvenile Polyposis Affect Cellular Localization

James R. Howe, Fadi S. Dahdaleh, Jennifer C. Carr, Donghong Wang, Scott K. Sherman, James R. Howe

J Surg Res. Author manuscript; available in PMC 2014 Oct 1.

Published in final edited form as: J Surg Res. 2013 Oct; 184(2): 739–745. Published online 2013 Feb 1. doi: 10.1016/j.jss.2013.01.015

PMCID:: PMC3683109

Abstract Article PDF–2.9M

Select item 36252058.

Bone Morphogenetic Protein Type I Receptor Antagonists Decrease Growth and Induce Cell Death of Lung Cancer Cell Lines

Elaine Langenfeld, Charles C. Hong, Gandhi Lanke, John Langenfeld

PLoS One. 2013; 8(4): e61256. Published online 2013 Apr 12. doi: 10.1371/journal.pone.0061256

PMCID:: PMC3625205

Abstract Article PDF–2.2M

Select item 29726979.

Discovery of the BMPR1A promoter and germline mutations that cause juvenile polyposis

Daniel Calva-Cerqueira, Fadi S. Dahdaleh, George Woodfield, Sathivel Chinnathambi, Peter L. Nagy, Joy Larsen-Haidle, Ronald J. Weigel, James R. Howe

Hum Mol Genet. 2010 Dec 1; 19(23): 4654–4662. Published online 2010 Sep 14. doi: 10.1093/hmg/ddq396

PMCID:: PMC2972697

Abstract Article PDF–491K

Select item 291730510.

Crystallization of BMP receptor type IA bound to the antibody Fab fragment AbD1556

Stefan Harth, Alexander Kotzsch, Walter Sebald, Thomas Dieter Mueller

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Aug 1; 66(Pt 8): 964–968. Published online 2010 Jul 29. doi: 10.1107/S1744309110024681

PMCID:: PMC2917305

Abstract Article PDF–387K

Select item 273153811.

Adipose Tissue Expression and Genetic Variants of the Bone Morphogenetic Protein Receptor 1A Gene (BMPR1A) Are Associated With Human Obesity

Yvonne Böttcher, Hanne Unbehauen, Nora Klöting, Karen Ruschke, Antje Körner, Dorit Schleinitz, Anke Tönjes, Beate Enigk, Sara Wolf, Kerstin Dietrich, Moritz Koriath, Gerhard Harry Scholz, Yu-Hua Tseng, Arne Dietrich, Michael R. Schön, Wieland Kiess, Michael Stumvoll, Matthias Blüher, Peter Kovacs

Diabetes. 2009 Sep; 58(9): 2119–2128. Published online 2009 Jun 5. doi: 10.2337/db08-1458

PMCID:: PMC2731538

Abstract Article PDF–185K

Select item 267427312.

A FAMILY WITH TWO CONSECUTIVE NONSENSE MUTATIONS IN BMPR1A CAUSING JUVENILE POLYPOSIS

James R. Howe, Sathivel Chinnathambi, Daniel Calva, Jennifer Bair, Brenda Pechman, Agnes Salamon, Beatrix Tam, Laszlo Simon

Cancer Genet Cytogenet. Author manuscript; available in PMC 2009 Apr 28.

Published in final edited form as: Cancer Genet Cytogenet. 2008 Feb; 181(1): 52–54. doi: 10.1016/j.cancergencyto.2007.11.001

PMCID:: PMC2674273

Abstract Article PDF–273K

Select item 1110778013.

Differential molecular regulation of processing and membrane expression of Type-I BMP receptors: implications for signaling

Tal Hirschhorn, Michal Levi-Hofman, Oded Danziger, Nechama I. Smorodinsky, Marcelo Ehrlich

Cell Mol Life Sci. 2017 Jul; 74(14): 2645–2662. Published online 2017 Mar 29. doi: 10.1007/s00018-017-2488-y

PMCID:: PMC11107780

Abstract Article PDF–3.6M

Select item 962449314.

Adenomatous Polyposis Phenotype in BMPR1A and SMAD4 Variant Carriers

Guy Rosner, Yael Petel-Galil, Ido Laish, Zohar Levi, Revital Kariv, Hana Strul, Ophir Gilad, Nathan Gluck

Clin Transl Gastroenterol. 2022 Oct; 13(10): e00527. Published online 2022 Aug 31. doi: 10.14309/ctg.0000000000000527

PMCID:: PMC9624493

Abstract Article PDF–558K

Select item 855795315.

Phenotypic differences in Juvenile Polyposis Syndrome with or without a disease-causing SMAD4/BMPR1A variant

Suzanne P. MacFarland, Jessica E. Ebrahimzadeh, Kristin Zelley, Lubna Begum, Lee M. Bass, Randall E. Brand, Beth Dudley, Douglas S. Fishman, Amanda Ganzak, Eve Karloski, Alicia Latham, Xavier Llor, Sharon Plon, Mary K. Riordan, Sarah R. Scollon, Zsofia K. Stadler, Sapna Syngal, Chinedu Ukaegbu, Jennifer M. Weiss, Matthew B. Yurgelun, Garrett M. Brodeur, Petar Mamula, Bryson W. Katona

Cancer Prev Res (Phila) Author manuscript; available in PMC 2021 Oct 31.

Published in final edited form as: Cancer Prev Res (Phila). 2021 Feb; 14(2): 215–222. Published online 2020 Oct 23. doi: 10.1158/1940-6207.CAPR-20-0348

PMCID:: PMC8557953

Abstract Article PDF–588K

Select item 746274316.

Disease expression in juvenile polyposis syndrome: a retrospective survey on a cohort of 221 European patients and comparison with a literature-derived cohort of 473 SMAD4/BMPR1A pathogenic variant carriers

Robert Blatter, Benjamin Tschupp, Stefan Aretz, Inge Bernstein, Chrystelle Colas, D. Gareth Evans, Maurizio Genuardi, Frederik J. Hes, Robert Hüneburg, Heikki Järvinen, Fiona Lalloo, Gabriela Moeslein, Laura Renkonen-Sinisalo, Nicoletta Resta, Isabel Spier, Dora Varvara, Hans Vasen, Andrew R. Latchford, Karl Heinimann

Genet Med. 2020; 22(9): 1524–1532. Published online 2020 May 13. doi: 10.1038/s41436-020-0826-1