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Items: 13

Select item 98397111.

Deficiency of transcription factor Nkx6.1 does not prevent insulin secretion in INS-1E cells

Vojtěch Pavluch, Hana Engstová, Jitka Špačková, Petr Ježek

Sci Rep. 2023; 13: 683. Published online 2023 Jan 13. doi: 10.1038/s41598-023-27985-7

PMCID:: PMC9839711

Abstract Article PDF–4.2M

Select item 10917522.

The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells

Jonathan C. Schisler, Per Bo Jensen, David G. Taylor, Thomas C. Becker, Filip Krag Knop, Shiro Takekawa, Michael German, Gordon C. Weir, Danhong Lu, Raghavendra G. Mirmira, Christopher B. Newgard

Proc Natl Acad Sci U S A. 2005 May 17; 102(20): 7297–7302. Published online 2005 May 9. doi: 10.1073/pnas.0502168102

PMCID:: PMC1091752

Abstract Article PDF–437K

Select item 56881093.

Nkx6.1 decline accompanies mitochondrial DNA reduction but subtle nucleoid size decrease in pancreatic islet β-cells of diabetic Goto Kakizaki rats

Tomáš Špaček, Vojtěch Pavluch, Lukáš Alán, Nikola Capková, Hana Engstová, Andrea Dlasková, Zuzana Berková, František Saudek, Petr Ježek

Sci Rep. 2017; 7: 15674. Published online 2017 Nov 15. doi: 10.1038/s41598-017-15958-6

PMCID:: PMC5688109

Abstract Article PDF–4.9M

Select item 45885484.

Aurora Kinase A is critical for the Nkx6.1 mediated β-cell proliferation pathway

Amanda Hobson, Carrie Draney, Andrew Stratford, Thomas C Becker, Danhong Lu, Michelle Arlotto, Jeffery S Tessem

Islets. 2015; 7(1): e1027854. Published online 2015 Jun 1. doi: 10.1080/19382014.2015.1027854

PMCID:: PMC4588548

Abstract Article PDF–788K

Select item 24231545.

Stimulation of Human and Rat Islet β-Cell Proliferation with Retention of Function by the Homeodomain Transcription Factor Nkx6.1

Jonathan C. Schisler, Patrick T. Fueger, Daniella A. Babu, Hans E. Hohmeier, Jeffery S. Tessem, Danhong Lu, Thomas C. Becker, Bashoo Naziruddin, Marlon Levy, Raghavendra G. Mirmira, Christopher B. Newgard

Mol Cell Biol. 2008 May; 28(10): 3465–3476. Published online 2008 Mar 17. doi: 10.1128/MCB.01791-07

PMCID:: PMC2423154

Abstract Article PDF–1.1M

Select item 39861386.

Nkx6.1 regulates islet β-cell proliferation via Nr4a1 and Nr4a3 nuclear receptors

Jeffery S. Tessem, Larry G. Moss, Lily C. Chao, Michelle Arlotto, Danhong Lu, Mette V. Jensen, Samuel B. Stephens, Peter Tontonoz, Hans E. Hohmeier, Christopher B. Newgard

Proc Natl Acad Sci U S A. 2014 Apr 8; 111(14): 5242–5247. Published online 2014 Mar 24. doi: 10.1073/pnas.1320953111

PMCID:: PMC3986138

Abstract Article PDF–1.1M

Select item 67404797.

Cross-Repressive Interaction of the Olig2 and Nkx2.2 Transcription Factors in Developing Neural Tube Associated with Formation of a Specific Physical Complex

Tao Sun, Hualing Dong, Lizi Wu, Michael Kane, David H. Rowitch, Charles D. Stiles

J Neurosci. 2003 Oct 22; 23(29): 9547–9556. doi: 10.1523/JNEUROSCI.23-29-09547.2003

PMCID:: PMC6740479

Abstract Article PDF–733K

Select item 41868658.

Control of Astrocyte Progenitor Specification, Migration and Maturation by Nkx6.1 Homeodomain Transcription Factor

Xiaofeng Zhao, Yidan Chen, Qiang Zhu, Hao Huang, Peng Teng, Kang Zheng, Xuemei Hu, Binghua Xie, Zunyi Zhang, Maike Sander, Mengsheng Qiu

PLoS One. 2014; 9(10): e109171. Published online 2014 Oct 6. doi: 10.1371/journal.pone.0109171

PMCID:: PMC4186865

Abstract Article PDF–8.5M

Select item 21211109.

The foxa2 Gene Controls the Birth and Spontaneous Degeneration of Dopamine Neurons in Old Age

Raja Kittappa, Wendy W Chang, Rajeshwar B Awatramani, Ronald D. G McKay

PLoS Biol. 2007 Dec; 5(12): e325. Published online 2007 Dec 11. doi: 10.1371/journal.pbio.0050325

PMCID:: PMC2121110

Abstract Article PDF–721K

Select item 214168610.

Loss of Myt1 function partially compromises endocrine islet cell differentiation and pancreatic physiological function in the mouse

Sui Wang, Jia Zhang, Aizhen Zhao, Susan Hipkens, Mark A. Magnuson, Guoqiang Gu

Mech Dev. Author manuscript; available in PMC 2008 Nov 1.

Published in final edited form as: Mech Dev. 2007; 124(11-12): 898–910. Published online 2007 Sep 4. doi: 10.1016/j.mod.2007.08.004

PMCID:: PMC2141686

Abstract Article PDF–4.0M

Select item 272933411.

Nkx6-1 controls the identity and fate of red nucleus and oculomotor neurons in the mouse midbrain

Nilima Prakash, Eduardo Puelles, Kristine Freude, Dietrich Trümbach, Daniela Omodei, Michela Di Salvio, Lori Sussel, Johan Ericson, Maike Sander, Antonio Simeone, Wolfgang Wurst

Development. 2009 Aug 1; 136(15): 2545–2555. Published online 2009 Jul 10. doi: 10.1242/dev.031781