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Select item 66739571.

Nedd4-WW Domain-Binding Protein 5 (Ndfip1) Is Associated with Neuronal Survival after Acute Cortical Brain Injury

Qian Sang, Mary H. Kim, Sharad Kumar, Nicole Bye, Maria C. Morganti-Kossman, Jenny Gunnersen, Stephanie Fuller, Jason Howitt, Lavinia Hyde, Tim Beissbarth, Hamish S. Scott, John Silke, Seong-Seng Tan

J Neurosci. 2006 Jul 5; 26(27): 7234–7244. doi: 10.1523/JNEUROSCI.1398-06.2006

PMCID:: PMC6673957

Abstract Article PDF–1.1M

Select item 33236172.

Gastrointestinal Microbiota Do Not Significantly Contribute to T Cell Activation or GI Inflammation in Ndfip1-cKO Mice

Vanessa Kurzweil, Amy Tarangelo, Paula M. Oliver

PLoS One. 2012; 7(4): e34478. Published online 2012 Apr 10. doi: 10.1371/journal.pone.0034478

PMCID:: PMC3323617

Abstract Article PDF–557K

Select item 61129803.

The Ubiquitin Ligase Adaptor NDFIP1 Selectively Enforces a CD8⁺ T Cell Tolerance Checkpoint to High-Dose Antigen

Mayura V. Wagle, Julia M. Marchingo, Jason Howitt, Seong-Seng Tan, Christopher C. Goodnow, Ian A. Parish

Cell Rep. Author manuscript; available in PMC 2018 Aug 28.

Published in final edited form as: Cell Rep. 2018 Jul 17; 24(3): 577–584. doi: 10.1016/j.celrep.2018.06.060

PMCID:: PMC6112980

Abstract Article PDF–833K

Select item 39054564.

The ubiquitin ligase adaptor Ndfip1 regulates T cell-mediated gastrointestinal inflammation and inflammatory bowel disease susceptibility

HE Ramon, CR Riling, J Bradfield, B Yang, H Hakonarson, PM Oliver

Mucosal Immunol. Author manuscript; available in PMC 2014 Jan 29.

Published in final edited form as: Mucosal Immunol. 2011 May; 4(3): 314–324. Published online 2010 Oct 20. doi: 10.1038/mi.2010.69

PMCID:: PMC3905456

Abstract Article PDF–2.4M

Select item 37134915.

The E3 ubiquitin ligase adaptor Ndfip1 regulates T_H17 differentiation by limiting the production of pro-inflammatory cytokines

Hilda E Ramon, Allison M Beal, Yuhong Liu, George Scott Worthen, Paula M Oliver

J Immunol. Author manuscript; available in PMC 2013 Jul 17.

Published in final edited form as: J Immunol. 2012 Apr 15; 188(8): 4023–4031. Published online 2012 Mar 7. doi: 10.4049/jimmunol.1102779

PMCID:: PMC3713491

Abstract Article PDF–1.1M

Select item 30487386.

Cellular Up-regulation of Nedd4 Family Interacting Protein 1 (Ndfip1) using Low Levels of Bioactive Cobalt Complexes

Christine Schieber, Jason Howitt, Ulrich Putz, Jonathan M. White, Clare L. Parish, Paul S. Donnelly, Seong-Seng Tan

J Biol Chem. 2011 Mar 11; 286(10): 8555–8564. Published online 2010 Dec 27. doi: 10.1074/jbc.M110.203448

PMCID:: PMC3048738

Abstract Article PDF–1.6M

Select item 52096877.

Ndfip1 restricts Th17 cell potency by limiting lineage stability and proinflammatory cytokine production

Awo Akosua Kesewa Layman, Stephanie L. Sprout, Dylan Phillips, Paula M. Oliver

Sci Rep. 2017; 7: 39649. Published online 2017 Jan 4. doi: 10.1038/srep39649

PMCID:: PMC5209687

Abstract Article PDF–2.0M

Select item 39260788.

Ndfip1 mediates peripheral tolerance to self and exogenous antigen by inducing cell cycle exit in responding CD4⁺ T cells

John A. Altin, Stephen R. Daley, Jason Howitt, Helen J. Rickards, Alison K. Batkin, Keisuke Horikawa, Simon J. Prasad, Keats A. Nelms, Sharad Kumar, Lawren C. Wu, Seong-Seng Tan, Matthew C. Cook, Christopher C. Goodnow

Proc Natl Acad Sci U S A. 2014 Feb 11; 111(6): 2067–2074. Published online 2014 Jan 13. doi: 10.1073/pnas.1322739111

PMCID:: PMC3926078

Abstract Article PDF–1.5M

Select item 39017329.

Increased Ndfip1 in the Substantia Nigra of Parkinsonian Brains Is Associated with Elevated Iron Levels

Jason Howitt, Amanda M. Gysbers, Scott Ayton, Francine Carew-Jones, Ulrich Putz, David I. Finkelstein, Glenda M. Halliday, Seong-Seng Tan

PLoS One. 2014; 9(1): e87119. Published online 2014 Jan 24. doi: 10.1371/journal.pone.0087119

PMCID:: PMC3901732

Abstract Article PDF–2.6M

Select item 354297810.

TGF-ß induces the expression of Nedd4 family-interacting protein 1 (Ndfip1) to silence IL-4 production during iT_reg cell differentiation

Allison M. Beal, Natalia Ramos-Hernández, Chris R. Riling, Erin A. Nowelsky, Paula M. Oliver

Nat Immunol. Author manuscript; available in PMC 2013 Jan 11.

Published in final edited form as: Nat Immunol. 2012 Jan; 13(1): 77–85. Published online 2011 Nov 13. doi: 10.1038/ni.2154

PMCID:: PMC3542978

Abstract Article PDF–5.3M

Select item 546537511.

Ndfip1 restricts mTORC1 signalling and glycolysis in regulatory T cells to prevent autoinflammatory disease

Awo Akosua Kesewa Layman, Guoping Deng, Claire E. O'Leary, Samuel Tadros, Rajan M. Thomas, Joseph M. Dybas, Emily K. Moser, Andrew D. Wells, Nicolai M. Doliba, Paula M. Oliver

Nat Commun. 2017; 8: 15677. Published online 2017 Jun 5. doi: 10.1038/ncomms15677

PMCID:: PMC5465375

Abstract Article PDF–1.7M

Select item 509529112.

The Nedd4-2/Ndfip1 axis is a negative regulator of IgE-mediated mast cell activation

Kwok Ho Yip, Natasha Kolesnikoff, Nicholas Hauschild, Lisa Biggs, Angel F. Lopez, Stephen J. Galli, Sharad Kumar, Michele A. Grimbaldeston

Nat Commun. 2016; 7: 13198. Published online 2016 Oct 27. doi: 10.1038/ncomms13198

PMCID:: PMC5095291

Abstract Article PDF–2.8M

Select item 483745013.

Ndfip-mediated degradation of Jak1 tunes cytokine signalling to limit expansion of CD4+ effector T cells

Claire E. O'Leary, Christopher R. Riling, Lynn A. Spruce, Hua Ding, Suresh Kumar, Guoping Deng, Yuhong Liu, Steven H. Seeholzer, Paula M. Oliver

Nat Commun. 2016; 7: 11226. Published online 2016 Apr 18. doi: 10.1038/ncomms11226

PMCID:: PMC4837450

Abstract Article PDF–2.3M

Select item 295596114.

Ndfip1 Protein Promotes the Function of Itch Ubiquitin Ligase to Prevent T Cell Activation and T Helper 2 Cell-Mediated Inflammation

Paula M. Oliver, Xiao Cao, George Scott Worthen, Peijun Shi, Natalie Briones, Megan MacLeod, Janice White, Patricia Kirby, John Kappler, Philippa Marrack, Baoli Yang

Immunity. Author manuscript; available in PMC 2010 Oct 16.

Published in final edited form as: Immunity. 2006 Dec; 25(6): 929–940. Published online 2006 Nov 30. doi: 10.1016/j.immuni.2006.10.012

PMCID:: PMC2955961

Abstract Article PDF–940K

Select item 1007901815.

Identification of Ndfip1 as a novel negative regulator for spatial memory formation associated with increased ubiquitination of Beclin 1 and PTEN

Wei-Lun Hsu, Yun-Li Ma, Yan-Chu Chen, Yen-Chen Liu, Kuang-Min Cheng, Eminy H. Y. Lee

PLoS One. 2023; 18(4): e0283908. Published online 2023 Apr 6. doi: 10.1371/journal.pone.0283908

PMCID:: PMC10079018

Abstract Article PDF–2.5M

Select item 325597116.

Ndfip1 regulates nuclear Pten import in vivo to promote neuronal survival following cerebral ischemia

Jason Howitt, Jenny Lackovic, Ley-Hian Low, Adam Naguib, Alison Macintyre, Choo-Peng Goh, Jennifer K. Callaway, Vicki Hammond, Tim Thomas, Matthew Dixon, Ulrich Putz, John Silke, Perry Bartlett, Baoli Yang, Sharad Kumar, Lloyd C. Trotman, Seong-Seng Tan

J Cell Biol. 2012 Jan 9; 196(1): 29–36. doi: 10.1083/jcb.201105009

PMCID:: PMC3255971

Abstract Article PDF–1.8M

Select item 385312117.

Ndfip1 enforces a requirement for CD28 co-stimulation by limiting IL-2 production

Natalia Ramos-Hernández, Hilda E. Ramon, Allison M. Beal, Ami Laroche, Erin A. Dekleva, Paula M. Oliver

J Immunol. Author manuscript; available in PMC 2014 Aug 15.

Published in final edited form as: J Immunol. 2013 Aug 15; 191(4): 10.4049/jimmunol.1203571. Published online 2013 Jul 12. doi: 10.4049/jimmunol.1203571

PMCID:: PMC3853121

Abstract Article PDF–2.6M

Select item 274127818.

Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons

Jason Howitt, Ulrich Putz, Jenny Lackovic, Anh Doan, Loretta Dorstyn, Hong Cheng, Baoli Yang, Tailoi Chan-Ling, John Silke, Sharad Kumar, Seong-Seng Tan

Proc Natl Acad Sci U S A. 2009 Sep 8; 106(36): 15489–15494. Published online 2009 Aug 25. doi: 10.1073/pnas.0904880106