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Select item 93576251.

ELOVL5‐mediated fatty acid elongation promotes cellular proliferation and invasion in renal cell carcinoma

Satoshi Nitta, Shuya Kandori, Ken Tanaka, Shotaro Sakka, Masanobu Siga, Yoshiyuki Nagumo, Hiromitsu Negoro, Takahiro Kojima, Bryan J. Mathis, Toru Shimazui, Takafumi Miyamoto, Takashi Matsuzaka, Hitoshi Shimano, Hiroyuki Nishiyama

Cancer Sci. 2022 Aug; 113(8): 2738–2752. Published online 2022 Jun 24. doi: 10.1111/cas.15454

PMCID:: PMC9357625

Abstract Article PDF–5.7M

Select item 56071702.

Methylation associated transcriptional repression of ELOVL5 in novel colorectal cancer cell lines

Arnoud Boot, Jan Oosting, Jaap D. H. van Eendenburg, Peter J. K. Kuppen, Hans Morreau, Tom van Wezel

PLoS One. 2017; 12(9): e0184900. Published online 2017 Sep 20. doi: 10.1371/journal.pone.0184900

PMCID:: PMC5607170

Abstract Article PDF–5.4M

Select item 38067133.

Genetic variation in fatty acid elongases is not associated with intermediate cardiovascular phenotypes or myocardial infarction

S Aslibekyan, MK Jensen, H Campos, CD Linkletter, EB Loucks, JM Ordovas, R Deka, EB Rimm, A Baylin

Eur J Clin Nutr. Author manuscript; available in PMC 2013 Oct 23.

Published in final edited form as: Eur J Clin Nutr. 2012 Mar; 66(3): 353–359. Published online 2012 Feb 1. doi: 10.1038/ejcn.2012.2

PMCID:: PMC3806713

Abstract Article PDF–66K

Select item 94400924.

Downregulation of Elovl5 promotes breast cancer metastasis through a lipid-droplet accumulation-mediated induction of TGF-β receptors

Trinh-Le-Vi Kieu, Léa Pierre, Valentin Derangère, Sabrina Perrey, Caroline Truntzer, Antoine Jalil, Sébastien Causse, Emma Groetz, Adélie Dumont, Laura Guyard, Laurent Arnould, Jean-Paul Pais de Barros, Lionel Apetoh, Cédric Rébé, Emeric Limagne, Tony Jourdan, Laurent Demizieux, David Masson, Charles Thomas, François Ghiringhelli, Mickaël Rialland

Cell Death Dis. 2022 Sep; 13(9): 758. Published online 2022 Sep 2. doi: 10.1038/s41419-022-05209-6

PMCID:: PMC9440092

Abstract Article PDF–5.9M

Select item 64951635.

DHA intake interacts with ELOVL2 and ELOVL5 genetic variants to influence polyunsaturated fatty acids in human milk

Yixia Wu (吴义霞), Yan Wang (王烟), Huimin Tian (田慧敏), Tong Lu (通逯), Miao Yu (于苗), Wenhui Xu (徐文慧), Guoliang Liu (刘国良), Lin Xie (谢林)

J Lipid Res. 2019 May; 60(5): 1043–1049. Published online 2019 Mar 26. doi: 10.1194/jlr.M090951

PMCID:: PMC6495163

Abstract Article PDF–649K

Select item 61737416.

Genome-wide methylation analysis identifies ELOVL5 as an epigenetic biomarker for the risk of type 2 diabetes mellitus

Joo-Yeon Hwang, Hyo Jung Lee, Min Jin Go, Han Byul Jang, Nak-Hyun Choi, Jae Bum Bae, Juan E. Castillo-Fernandez, Jordana T. Bell, Tim D. Spector, Hye-Ja Lee, Bong-Jo Kim

Sci Rep. 2018; 8: 14862. Published online 2018 Oct 5. doi: 10.1038/s41598-018-33238-9

PMCID:: PMC6173741

Abstract Article PDF–1.4M

Select item 41294087.

ELOVL5 Mutations Cause Spinocerebellar Ataxia 38

Eleonora Di Gregorio, Barbara Borroni, Elisa Giorgio, Daniela Lacerenza, Marta Ferrero, Nicola Lo Buono, Neftj Ragusa, Cecilia Mancini, Marion Gaussen, Alessandro Calcia, Nico Mitro, Eriola Hoxha, Isabella Mura, Domenico A. Coviello, Young-Ah Moon, Christelle Tesson, Giovanna Vaula, Philippe Couarch, Laura Orsi, Eleonora Duregon, Mauro Giulio Papotti, Jean-François Deleuze, Jean Imbert, Chiara Costanzi, Alessandro Padovani, Paola Giunti, Marcel Maillet-Vioud, Alexandra Durr, Alexis Brice, Filippo Tempia, Ada Funaro, Loredana Boccone, Donatella Caruso, Giovanni Stevanin, Alfredo Brusco

Am J Hum Genet. 2014 Aug 7; 95(2): 209–217. doi: 10.1016/j.ajhg.2014.07.001

PMCID:: PMC4129408

Abstract Article PDF–2.6M

Select item 35205428.

Elovl5 regulates the mTORC2-Akt-FOXO1 pathway by controlling hepatic cis-vaccenic acid synthesis in diet-induced obese mice

Sasmita Tripathy, Donald B. Jump

J Lipid Res. 2013 Jan; 54(1): 71–84. doi: 10.1194/jlr.M028787

PMCID:: PMC3520542

Abstract Article PDF–1.8M

Select item 32852979.

Validation of the Health ABC Heart Failure Model for Incident Heart Failure Risk Prediction: The Cardiovascular Health Study

Andreas Kalogeropoulos, Bruce M. Psaty, Ramachandran S. Vasan, Vasiliki Georgiopoulou, Andrew L. Smith, Nicholas L. Smith, Stephen B. Kritchevsky, Peter W.F. Wilson, Anne B. Newman, Tamara B. Harris, Javed Butler

Circ Heart Fail. Author manuscript; available in PMC 2012 Feb 23.

Published in final edited form as: Circ Heart Fail. 2010 Jul; 3(4): 495–502. Published online 2010 Apr 28. doi: 10.1161/CIRCHEARTFAILURE.109.904300

PMCID:: PMC3285297

Abstract Article PDF–743K

Select item 304417210.

Genetic Variants of the FADS Gene Cluster and ELOVL Gene Family, Colostrums LC-PUFA Levels, Breastfeeding, and Child Cognition

Eva Morales, Mariona Bustamante, Juan Ramon Gonzalez, Monica Guxens, Maties Torrent, Michelle Mendez, Raquel Garcia-Esteban, Jordi Julvez, Joan Forns, Martine Vrijheid, Carolina Molto-Puigmarti, Carmen Lopez-Sabater, Xavier Estivill, Jordi Sunyer

PLoS One. 2011; 6(2): e17181. Published online 2011 Feb 23. doi: 10.1371/journal.pone.0017181

PMCID:: PMC3044172

Abstract Article PDF–328K

Select item 380551011.

Gene Expression of Desaturase (FADS1 and FADS2) and Elongase (ELOVL5) Enzymes in Peripheral Blood: Association with Polyunsaturated Fatty Acid Levels and Atopic Eczema in 4-Year-Old Children

Aida Maribel Chisaguano, Rosa Montes, Teresa Pérez-Berezo, Ana Isabel Castellote, Marcela Guerendiain, Mariona Bustamante, Eva Morales, Raquel García-Esteban, Jordi Sunyer, Àngels Franch, M. Carmen López-Sabater

PLoS One. 2013; 8(10): e78245. Published online 2013 Oct 22. doi: 10.1371/journal.pone.0078245

PMCID:: PMC3805510

Abstract Article PDF–465K

Select item 122130812.

Cloning of a human cDNA encoding a novel enzyme involved in the elongation of long-chain polyunsaturated fatty acids.

A E Leonard, E G Bobik, J Dorado, P E Kroeger, L T Chuang, J M Thurmond, J M Parker-Barnes, T Das, Y S Huang, P Mukerji

Biochem J. 2000 Sep 15; 350(Pt 3): 765–770.

PMCID:: PMC1221308

Summary PDF–197K

Select item 412112513.

MicroRNA-30c reduces hyperlipidemia and atherosclerosis by decreasing lipid synthesis and lipoprotein secretion

James Soh, Jahangir Iqbal, Joyce Queiroz, Carlos Fernandez-Hernando, M. Mahmood Hussain

Nat Med. Author manuscript; available in PMC 2014 Aug 4.

Published in final edited form as: Nat Med. 2013 Jul; 19(7): 892–900. Published online 2013 Jun 9. doi: 10.1038/nm.3200

PMCID:: PMC4121125

Abstract Article PDF–2.0M

Select item 297300214.

ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis

Yusuke Ohno, Shota Suto, Masao Yamanaka, Yukiko Mizutani, Susumu Mitsutake, Yasuyuki Igarashi, Takayuki Sassa, Akio Kihara

Proc Natl Acad Sci U S A. 2010 Oct 26; 107(43): 18439–18444. Published online 2010 Oct 11. doi: 10.1073/pnas.1005572107

PMCID:: PMC2973002

Abstract Article PDF–1.2M

Select item 180207715.

Mapping of transcription start sites of human retina expressed genes

Valeria Roni, Ronald Carpio, Bernd Wissinger

BMC Genomics. 2007; 8: 42. Published online 2007 Feb 7. doi: 10.1186/1471-2164-8-42

PMCID:: PMC1802077

Abstract Article PDF–578K

Select item 629936816.

The intracellular NADH level regulates atrophic nonunion pathogenesis through the CtBP2-p300-Runx2 transcriptional complex

Wentao Zhang, Ning Duan, Qian Zhang, Tao Song, Zhong Li, Xun Chen, Kunzheng Wang

Int J Biol Sci. 2018; 14(14): 2023–2036. Published online 2018 Nov 3. doi: 10.7150/ijbs.28302

PMCID:: PMC6299368

Abstract Article PDF–2.0M

Select item 603071917.

CRISPR/Cas9-mediated Genomic Editing of Cluap1/IFT38 Reveals a New Role in Actin Arrangement

Tina Beyer, Sylvia Bolz, Katrin Junger, Nicola Horn, Muhammad Moniruzzaman, Yasmin Wissinger, Marius Ueffing, Karsten Boldt

Mol Cell Proteomics. 2018 Jul; 17(7): 1285–1294. Published online 2018 Apr 3. doi: 10.1074/mcp.RA117.000487

PMCID:: PMC6030719

Abstract Article PDF–2.7M

Select item 823607818.

Comparative Host Interactomes of the SARS-CoV-2 Nonstructural Protein 3 and Human Coronavirus Homologs

Katherine M. Almasy, Jonathan P. Davies, Lars Plate

Mol Cell Proteomics. 2021; 20: 100120. Published online 2021 Jun 27. doi: 10.1016/j.mcpro.2021.100120

PMCID:: PMC8236078

Abstract Article PDF–4.6M

Select item 13914619.

Large-Scale Concatenation cDNA Sequencing

Wei Yu, Björn Andersson, Kim C. Worley, Donna M. Muzny, Yan Ding, Wen Liu, Jennifer Y. Ricafrente, Meredith A. Wentland, Greg Lennon, Richard A. Gibbs

Genome Res. 1997 Apr; 7(4): 353–358. doi: 10.1101/gr.7.4.353

PMCID:: PMC139146

Abstract Article PDF–62K

Select item 1064152420.

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis

Robert S. Kiss, Jarred Chicoine, Youssef Khalil, Robert Sladek, He Chen, Alessandro Pisaturo, Cyril Martin, Jessica D. Dale, Tegan A. Brudenell, Archith Kamath, Jeffrey Kyei-Boahen, Anouar Hafiane, Girija Daliah, Célia Alecki, Tayah S. Hopes, Martin Heier, Irene A. Aligianis, Jean-Jacques Lebrun, Julie Aspden, Emanuele Paci, Anja Kerksiek, Dieter Lütjohann, Peter Clayton, Jimi C. Wills, Alex von Kriegsheim, Tommy Nilsson, Eamonn Sheridan, Mark T. Handley

J Biol Chem. 2023 Nov; 299(11): 105295. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105295

PMCID:: PMC10641524

Abstract Article PDF–3.8M

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