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Items: 1 to 20 of 35

1.
RGS7 balances acetylation/de-acetylation of p65 to control chemotherapy-dependent cardiac inflammation
Madhuri Basak, Kiran Das, Tarun Mahata, Dinesh Kumar, Nupur Nagar, Krishna Mohan Poluri, Pranesh Kumar, Priyadip Das, Adele Stewart, Biswanath Maity
Cell Mol Life Sci. 2023 Sep; 80(9): 255. Published online 2023 Aug 17. doi: 10.1007/s00018-023-04895-5
PMCID:
PMC11071981
AbstractArticlePDF–9.1M
2.
RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells
Nouar Qutob, Ikuo Masuho, Michal Alon, Rafi Emmanuel, Isadora Cohen, Antonella Di Pizio, Jason Madore, Abdel Elkahloun, Tamar Ziv, Ronen Levy, Jared J. Gartner, Victoria K. Hill, Jimmy C. Lin, Yael Hevroni, Polina Greenberg, Alexandra Brodezki, Steven A. Rosenberg, Mickey Kosloff, Nicholas K. Hayward, Arie Admon, Masha Y. Niv, Richard A. Scolyer, Kirill A. Martemyanov, Yardena Samuels
Sci Rep. 2018; 8: 653. Published online 2018 Jan 12. doi: 10.1038/s41598-017-18851-4
Correction in:
Sci Rep. 2019; 9: 4523.
PMCID:
PMC5766496
AbstractArticlePDF–1.2M
3.
A RGS7-CaMKII complex drives myocyte-intrinsic and myocyte-extrinsic mechanisms of chemotherapy-induced cardiotoxicity
Madhuri Basak, Abhishek Singh Sengar, Kiran Das, Tarun Mahata, Manish Kumar, Dinesh Kumar, Sayan Biswas, Subhasish Sarkar, Pranesh Kumar, Priyadip Das, Adele Stewart, Biswanath Maity
Proc Natl Acad Sci U S A. 2023 Jan 3; 120(1): e2213537120. Published online 2022 Dec 27. doi: 10.1073/pnas.2213537120
PMCID:
PMC9910480
AbstractArticlePDF–9.9M
4.
Fine mapping of the uterine leiomyoma locus on 1q43 close to a lncRNA in the RGS7-FH interval
Brahim Aissani, Kui Zhang, Arjen R Mensenkamp, Fred H Menko, Howard W Wiener
Endocr Relat Cancer. 2015 Aug; 22(4): 633–643. Prepublished online 2015 Jun 25. doi: 10.1530/ERC-15-0208
PMCID:
PMC4526794
AbstractArticlePDF–308K
5.
Macromolecular Composition Dictates Receptor and G Protein Selectivity of Regulator of G Protein Signaling (RGS) 7 and 9-2 Protein Complexes in Living Cells
Ikuo Masuho, Keqiang Xie, Kirill A. Martemyanov
J Biol Chem. 2013 Aug 30; 288(35): 25129–25142. Published online 2013 Jul 15. doi: 10.1074/jbc.M113.462283
PMCID:
PMC3757177
AbstractArticlePDF–4.8M
6.
Interaction between RGS7 and polycystin
Emily Kim, Thierry Arnould, Lorenz Sellin, Thomas Benzing, Natalia Comella, Olivier Kocher, Leonidas Tsiokas, Vikas P. Sukhatme, Gerd Walz
Proc Natl Acad Sci U S A. 1999 May 25; 96(11): 6371–6376. doi: 10.1073/pnas.96.11.6371
PMCID:
PMC26888
AbstractArticlePDF–351K
7.
Gβ5 prevents the RGS7-Gαo interaction through binding to a distinct Gγ-like domain found in RGS7 and other RGS proteins
Konstantin Levay, Jorge L. Cabrera, Daulet K. Satpaev, Vladlen Z. Slepak
Proc Natl Acad Sci U S A. 1999 Mar 2; 96(5): 2503–2507. doi: 10.1073/pnas.96.5.2503
PMCID:
PMC26814
AbstractArticlePDF–203K
8.
Orphan receptor GPR158 serves as a metabotropic glycine receptor: mGlyR
Thibaut Laboute, Stefano Zucca, Matthew Holcomb, Dipak N. Patil, Christina Garza, Brittany A. Wheatley, Raktim N. Roy, Stefano Forli, Kirill A. Martemyanov
Science. Author manuscript; available in PMC 2024 Mar 31.
Published in final edited form as: Science. 2023 Mar 31; 379(6639): 1352–1358. Published online 2023 Mar 30. doi: 10.1126/science.add7150
PMCID:
PMC10751545
AbstractArticlePDF–2.3M
9.
Cryo-EM structure of human GPR158 receptor coupled to the RGS7-Gβ5 signaling complex
Dipak N. Patil, Shikha Singh, Thibaut Laboute, Timothy S. Strutzenberg, Xingyu Qiu, Di Wu, Scott J. Novick, Carol V. Robinson, Patrick R. Griffin, John F. Hunt, Tina Izard, Appu K. Singh, Kirill A. Martemyanov
Science. Author manuscript; available in PMC 2023 Jan 7.
Published in final edited form as: Science. 2022 Jan 7; 375(6576): 86–91. Published online 2021 Nov 18. doi: 10.1126/science.abl4732
PMCID:
PMC8926151
AbstractArticlePDF–1.0M
10.
Structure of the class C orphan GPCR GPR158 in complex with RGS7-Gβ5
Eunyoung Jeong, Yoojoong Kim, Jihong Jeong, Yunje Cho
Nat Commun. 2021; 12: 6805. Published online 2021 Nov 23. doi: 10.1038/s41467-021-27147-1
PMCID:
PMC8611064
AbstractArticlePDF–2.7M
11.
Structural organization of a major neuronal G protein regulator, the RGS7-Gβ5-R7BP complex
Dipak N Patil, Erumbi S Rangarajan, Scott J Novick, Bruce D Pascal, Douglas J Kojetin, Patrick R Griffin, Tina Izard, Kirill A Martemyanov
eLife. 2018; 7: e42150. Published online 2018 Dec 12. doi: 10.7554/eLife.42150
PMCID:
PMC6310461
AbstractArticlePDF–6.0M
12.
Regulation of neurite morphogenesis by interaction between R7 regulator of G protein signaling complexes and G protein subunit Gα13
Stephanie L. Scherer, Matthew D. Cain, Stanley M. Kanai, Kevin M. Kaltenbronn, Kendall J. Blumer
J Biol Chem. 2017 Jun 16; 292(24): 9906–9918. Published online 2017 Apr 21. doi: 10.1074/jbc.M116.771923
PMCID:
PMC5473243
AbstractArticlePDF–1.6M
13.
Regulator of G Protein Signaling 7 (RGS7) Can Exist in a Homo-oligomeric Form That Is Regulated by Gαo and R7-binding Protein
Junior Tayou, Qiang Wang, Geeng-Fu Jang, Alexey N. Pronin, Cesare Orlandi, Kirill A. Martemyanov, John W. Crabb, Vladlen Z. Slepak
J Biol Chem. 2016 Apr 22; 291(17): 9133–9147. Published online 2016 Feb 19. doi: 10.1074/jbc.M115.694075
PMCID:
PMC4861480
AbstractArticlePDF–3.1M
14.
Gβ5-RGS7 selectively inhibits muscarinic M3 receptor signaling via the interaction between the third intracellular loop of the receptor and the DEP domain of RGS7
Simone L. Sandiford, Vladlen Z. Slepak
Biochemistry. Author manuscript; available in PMC 2010 Mar 17.
Published in final edited form as: Biochemistry. 2009 Mar 17; 48(10): 2282–2289. doi: 10.1021/bi801989c
PMCID:
PMC2766429
AbstractArticlePDF–843K
15.
Gi/o Signaling and the Palmitoyltransferase DHHC2 Regulate Palmitate Cycling and Shuttling of RGS7 Family-binding Protein
Lixia Jia, Maurine E. Linder, Kendall J. Blumer
J Biol Chem. 2011 Apr 15; 286(15): 13695–13703. Published online 2011 Feb 22. doi: 10.1074/jbc.M110.193763
PMCID:
PMC3075713
AbstractArticlePDF–1.9M
16.
A G protein γ subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gβ5 subunits
Bryan E. Snow, Andrejs M. Krumins, Greg M. Brothers, Sheu-Fen Lee, Mark A. Wall, Stephen Chung, Joan Mangion, Sudha Arya, Alfred G. Gilman, David P. Siderovski
Proc Natl Acad Sci U S A. 1998 Oct 27; 95(22): 13307–13312. doi: 10.1073/pnas.95.22.13307
PMCID:
PMC23793
AbstractArticlePDF–542K
17.
Fidelity of G protein β-subunit association by the G protein γ-subunit-like domains of RGS6, RGS7, and RGS11
Bryan E. Snow, Laurie Betts, Joan Mangion, John Sondek, David P. Siderovski
Proc Natl Acad Sci U S A. 1999 May 25; 96(11): 6489–6494. doi: 10.1073/pnas.96.11.6489
PMCID:
PMC26909
AbstractArticlePDF–545K
18.
GWAS of Longevity in CHARGE Consortium Confirms APOE and FOXO3 Candidacy
Linda Broer, Aron S. Buchman, Joris Deelen, Daniel S. Evans, Jessica D. Faul, Kathryn L. Lunetta, Paola Sebastiani, Jennifer A. Smith, Albert V. Smith, Toshiko Tanaka, Lei Yu, Alice M. Arnold, Thor Aspelund, Emelia J. Benjamin, Philip L. De Jager, Gudny Eirkisdottir, Denis A. Evans, Melissa E. Garcia, Albert Hofman, Robert C. Kaplan, Sharon L. R. Kardia, Douglas P. Kiel, Ben A. Oostra, Eric S. Orwoll, Neeta Parimi, Bruce M. Psaty, Fernando Rivadeneira, Jerome I. Rotter, Sudha Seshadri, Andrew Singleton, Henning Tiemeier, André G. Uitterlinden, Wei Zhao, Stefania Bandinelli, David A. Bennett, Luigi Ferrucci, Vilmundur Gudnason, Tamara B. Harris, David Karasik, Lenore J. Launer, Thomas T. Perls, P. Eline Slagboom, Gregory J. Tranah, David R. Weir, Anne B. Newman, Cornelia M. van Duijn, Joanne M. Murabito
J Gerontol A Biol Sci Med Sci. 2015 Jan; 70(1): 110–118. Published online 2014 Sep 8. doi: 10.1093/gerona/glu166
PMCID:
PMC4296168
AbstractArticlePDF–311K
19.
Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes
Maggie C. Y. Ng, Daniel Shriner, Brian H. Chen, Jiang Li, Wei-Min Chen, Xiuqing Guo, Jiankang Liu, Suzette J. Bielinski, Lisa R. Yanek, Michael A. Nalls, Mary E. Comeau, Laura J. Rasmussen-Torvik, Richard A. Jensen, Daniel S. Evans, Yan V. Sun, Ping An, Sanjay R. Patel, Yingchang Lu, Jirong Long, Loren L. Armstrong, Lynne Wagenknecht, Lingyao Yang, Beverly M. Snively, Nicholette D. Palmer, Poorva Mudgal, Carl D. Langefeld, Keith L. Keene, Barry I. Freedman, Josyf C. Mychaleckyj, Uma Nayak, Leslie J. Raffel, Mark O. Goodarzi, Y-D Ida Chen, Herman A. Taylor, Jr., Adolfo Correa, Mario Sims, David Couper, James S. Pankow, Eric Boerwinkle, Adebowale Adeyemo, Ayo Doumatey, Guanjie Chen, Rasika A. Mathias, Dhananjay Vaidya, Andrew B. Singleton, Alan B. Zonderman, Robert P. Igo, Jr., John R. Sedor, the FIND Consortium, Edmond K. Kabagambe, David S. Siscovick, Barbara McKnight, Kenneth Rice, Yongmei Liu, Wen-Chi Hsueh, Wei Zhao, Lawrence F. Bielak, Aldi Kraja, Michael A. Province, Erwin P. Bottinger, Omri Gottesman, Qiuyin Cai, Wei Zheng, William J. Blot, William L. Lowe, Jennifer A. Pacheco, Dana C. Crawford, the eMERGE Consortium, the DIAGRAM Consortium, Elin Grundberg, the MuTHER Consortium, Stephen S. Rich, M. Geoffrey Hayes, Xiao-Ou Shu, Ruth J. F. Loos, Ingrid B. Borecki, Patricia A. Peyser, Steven R. Cummings, Bruce M. Psaty, Myriam Fornage, Sudha K. Iyengar, Michele K. Evans, Diane M. Becker, W. H. Linda Kao, James G. Wilson, Jerome I. Rotter, Michèle M. Sale, Simin Liu, Charles N. Rotimi, Donald W. Bowden, for the MEta-analysis of type 2 DIabetes in African Americans (MEDIA) Consortium
PLoS Genet. 2014 Aug; 10(8): e1004517. Published online 2014 Aug 7. doi: 10.1371/journal.pgen.1004517
PMCID:
PMC4125087
AbstractArticlePDF–1.0M
20.
Genetic variations in regulator of G-protein signaling genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma
Jianming Wang, Scott M. Lippman, J.Jack Lee, Hushan Yang, Fadlo R. Khuri, Edward Kim, Jie Lin, David W. Chang, Reuben Lotan, Waun K. Hong, Xifeng Wu
Carcinogenesis. 2010 Oct; 31(10): 1755–1761. Published online 2010 Jul 12. doi: 10.1093/carcin/bgq138
PMCID:
PMC2950933
AbstractArticlePDF–131K

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