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Select item 110251951.

Analysis of REST binding sites with canonical and non-canonical motifs in human cell lines

Jaejoon Choi, Eunjung Alice Lee

BMC Med Genomics. 2024; 17(Suppl 1): 92. Published online 2024 Apr 17. doi: 10.1186/s12920-024-01860-4

PMCID:: PMC11025195

Abstract Article PDF–1.7M

Select item 106051572.

REST Is Not Resting: REST/NRSF in Health and Disease

Lili Jin, Ying Liu, Yifan Wu, Yi Huang, Dianbao Zhang

Biomolecules. 2023 Oct; 13(10): 1477. Published online 2023 Oct 2. doi: 10.3390/biom13101477

PMCID:: PMC10605157

Abstract Article PDF–1.0M

Select item 105563983.

Genome-wide Association Studies of REST Gene Associated Neurological Diseases/traits with Related Single Nucleotide Polymorphisms

Jingjing Wang, Sagor Kumar Roy, Seidu A. Richard, Yuming Xu

Curr Neurovasc Res. 2023; 20(3): 410–422. Published online 2023. doi: 10.2174/1567202620666230727153306

PMCID:: PMC10556398

Abstract Article PDF–4.2M

Select item 104716934.

Repressor Element-1 Binding Transcription Factor (REST) as a Possible Epigenetic Regulator of Neurodegeneration and MicroRNA-Based Therapeutic Strategies

Ajmal Nassar, Sairaj Satarker, Prasada Chowdari Gurram, Dinesh Upadhya, SM Fayaz, Madhavan Nampoothiri

Mol Neurobiol. 2023; 60(10): 5557–5577. Published online 2023 Jun 16. doi: 10.1007/s12035-023-03437-1

PMCID:: PMC10471693

Abstract Article PDF–3.4M

Select item 103932285.

REST contributes to AKI-to-CKD transition through inducing ferroptosis in renal tubular epithelial cells

Shuiqin Gong, Aihong Zhang, Mengying Yao, Wang Xin, Xu Guan, Shaozong Qin, Yong Liu, Jiachuan Xiong, Ke Yang, Li Xiong, Ting He, Yinghui Huang, Jinghong Zhao

JCI Insight. 2023 Jun 8; 8(11): e166001. Published online 2023 Jun 8. doi: 10.1172/jci.insight.166001

PMCID:: PMC10393228

Abstract Article PDF–27M

Select item 102578536.

DNA methylation alterations at RE1-silencing transcription factor binding sites and their flanking regions in cancer

Ana Florencia Vega-Benedetti, Eleonora Loi, Loredana Moi, Patrizia Zavattari

Clin Epigenetics. 2023; 15: 98. Published online 2023 Jun 10. doi: 10.1186/s13148-023-01514-9

PMCID:: PMC10257853

Abstract Article PDF–7.0M

Select item 100544787.

REST/NRSF Silencing Modifies Neuronal Gene Expression in siRNA-Treated HeLa Cells: A Preliminary Exploration in the Search for Neuronal Biomarkers of Cervical Cancer

Karen Cortés-Sarabia, Luz Del Carmen Alarcón-Romero, Miguel Ángel Mendoza-Catalán, Juan Carlos Carpio-Pedroza, Eduardo Castañeda-Saucedo, Carlos Ortuño-Pineda

Medicina (Kaunas) 2023 Mar; 59(3): 537. Published online 2023 Mar 9. doi: 10.3390/medicina59030537

PMCID:: PMC10054478

Abstract Article PDF–1.1M

Select item 91582008.

Plasma repressor element 1-silencing transcription factor levels are decreased in patients with Alzheimer's disease

Mingqing Wei, Jingnian Ni, Jing Shi, Ting Li, Xiaoqing Xu, Chenmeng Li, Bin Qin, Dongsheng Fan, Hengge Xie, Zhong Wang, Yongyan Wang, Tao Lu, Jinzhou Tian

BMC Geriatr. 2022; 22: 471. Published online 2022 Jun 1. doi: 10.1186/s12877-022-03163-8

PMCID:: PMC9158200

Abstract Article PDF–829K

Select item 90685669.

Significant decrease of a master regulator of genes (REST/NRSF) in high-grade squamous intraepithelial lesion and cervical cancer

Karen Cortés-Sarabia, Luz del Carmen Alarcón-Romero, Eugenia Flores-Alfaro, Berenice Illades-Aguiar, Amalia Vences-Velázquez, Miguel Ángel Mendoza-Catalán, Napoleón Navarro-Tito, Jesús Valdés, Ma Elena Moreno-Godínez, Carlos Ortuño-Pineda

Biomed J. 2021 Dec; 44(6 Suppl 2): S171–S178. Published online 2020 Aug 27. doi: 10.1016/j.bj.2020.08.012

PMCID:: PMC9068566

Abstract Article PDF–1.6M

Select item 869982410.

Reprogramming Human Adult Fibroblasts into GABAergic Interneurons

Andreas Bruzelius, Srisaiyini Kidnapillai, Janelle Drouin-Ouellet, Tom Stoker, Roger A. Barker, Daniella Rylander Ottosson

Cells. 2021 Dec; 10(12): 3450. Published online 2021 Dec 8. doi: 10.3390/cells10123450

PMCID:: PMC8699824

Abstract Article PDF–2.9M

Select item 822136111.

Repressor element-1 silencing transcription factor regulates glutamate receptors and immediate early genes to affect synaptic plasticity

Chenhaoyi Xu, Min Zhang, Lu Zu, Pei Zhang, Letao Sun, Xueyuan Liu, Min Fang

Aging (Albany NY) 2021 Jun 15; 13(11): 15569–15579. Published online 2021 Jun 9. doi: 10.18632/aging.203118

PMCID:: PMC8221361

Abstract Article PDF–868K

Select item 809483812.

Analysis of the Repressor Element‐1 Silencing Transcription Factor/Neuron‐Restrictive Silencer Factor Occupancy of Non‐Neuronal Genes in Peripheral Lymphocytes from Patients with Huntington's Disease

Manuela Marullo, Marta Valenza, Caterina Mariotti, Stefano Di Donato, Elena Cattaneo, Chiara Zuccato

Brain Pathol. 2010 Jan; 20(1): 96–105. Published online 2009 Jan 5. doi: 10.1111/j.1750-3639.2008.00249.x

PMCID:: PMC8094838

Abstract Article PDF–302K

Select item 801213113.

Low REST Expression Indicates a Biomarker of Poor Prognosis in Patients with Renal Cell Carcinoma

Chaoxiang Lv, Yuanguo Li, Qiqi Zhang, Yanyan Chen, Dandan Wei, Tiecheng Wang, Bo Zhou

Biomed Res Int. 2021; 2021: 6682758. Published online 2021 Mar 24. doi: 10.1155/2021/6682758

PMCID:: PMC8012131

Abstract Article PDF–1.5M

Select item 784119514.

Demethylation of Repressor Element-1 Silencing Transcription (REST) Suppresses the Malignant Phenotype of Breast Cancer via MMP9

Ying Liu, Hui Lv, Xiaoying Wu, Jun Zhou, Ying Shi, Jifang Wen

Oncol Res. 2017; 25(3): 445–454. Published online 2017 Mar 13. doi: 10.3727/096504016X14747368729786

PMCID:: PMC7841195

Abstract Article PDF–18M

Select item 753664515.

Ovarian Cancer Risk Variants Are Enriched in Histotype-Specific Enhancers and Disrupt Transcription Factor Binding Sites

Michelle R. Jones, Pei-Chen Peng, Simon G. Coetzee, Jonathan Tyrer, Alberto Luiz P. Reyes, Rosario I. Corona, Brian Davis, Stephanie Chen, Felipe Dezem, Ji-Heui Seo, Siddartha Kar, Eileen Dareng, Ovarian Cancer Association Consortium, Benjamin P. Berman, Matthew L. Freedman, Jasmine T. Plummer, Kate Lawrenson, Paul Pharoah, Dennis J. Hazelett, Simon A. Gayther

Am J Hum Genet. 2020 Oct 1; 107(4): 622–635. Published online 2020 Sep 17. doi: 10.1016/j.ajhg.2020.08.021

PMCID:: PMC7536645

Abstract Article PDF–1.6M

Select item 638619616.

REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer’s Disease

Katharina Meyer, Heather M. Feldman, Tao Lu, Derek Drake, Elaine T. Lim, King-Hwa Ling, Nicholas A. Bishop, Ying Pan, Jinsoo Seo, Yuan-Ta Lin, Susan C. Su, George M. Church, Li-Huei Tsai, Bruce A. Yankner

Cell Rep. Author manuscript; available in PMC 2019 Feb 22.

Published in final edited form as: Cell Rep. 2019 Jan 29; 26(5): 1112–1127.e9. doi: 10.1016/j.celrep.2019.01.023

PMCID:: PMC6386196

Abstract Article PDF–3.7M

Select item 589283817.

REST, a master transcriptional regulator in neurodegenerative disease

Jee-Yeon Hwang, R Suzanne Zukin

Curr Opin Neurobiol. Author manuscript; available in PMC 2018 Apr 10.

Published in final edited form as: Curr Opin Neurobiol. 2018 Feb; 48: 193–200. Published online 2018 Jan 30. doi: 10.1016/j.conb.2017.12.008

PMCID:: PMC5892838

Abstract Article PDF–652K

Select item 550186818.

REST Final-Exon-Truncating Mutations Cause Hereditary Gingival Fibromatosis

Yavuz Bayram, Janson J. White, Nursel Elcioglu, Megan T. Cho, Neda Zadeh, Asuman Gedikbasi, Sukru Palanduz, Sukru Ozturk, Kivanc Cefle, Ozgur Kasapcopur, Zeynep Coban Akdemir, Davut Pehlivan, Amber Begtrup, Claudia M.B. Carvalho, Ingrid Sophie Paine, Ali Mentes, Kivanc Bektas-Kayhan, Ender Karaca, Shalini N. Jhangiani, Donna M. Muzny, Baylor-Hopkins Center for Mendelian Genomics, Richard A. Gibbs, James R. Lupski

Am J Hum Genet. 2017 Jul 6; 101(1): 149–156. Published online 2017 Jul 6. doi: 10.1016/j.ajhg.2017.06.006

PMCID:: PMC5501868

Abstract Article PDF–775K

Select item 540542119.

Stepwise assembly of functional C‐terminal REST/NRSF transcriptional repressor complexes as a drug target

Ken Inui, Zongpei Zhao, Juan Yuan, Sakthidasan Jayaprakash, Le T. M. Le, Srdja Drakulic, Bjoern Sander, Monika M. Golas

Protein Sci. 2017 May; 26(5): 997–1011. Published online 2017 Mar 12. doi: 10.1002/pro.3142

PMCID:: PMC5405421

Abstract Article PDF–6.4M

Select item 504829320.

An expression based REST signature predicts patient survival and therapeutic response for glioblastoma multiforme

Jianfeng Liang, Qinghua Meng, Wanni Zhao, Pan Tong, Ping Li, Yuanli Zhao, Xiaodong Zhao, Hua Li

Sci Rep. 2016; 6: 34556. Published online 2016 Oct 4. doi: 10.1038/srep34556

PMCID:: PMC5048293

Abstract Article PDF–1.7M

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