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Select item 66233271.

Interplay among cGMP, cAMP, and Ca²⁺ in Living Olfactory Sensory Neurons In Vitro and In Vivo

Mara Pietrobon, Ilaria Zamparo, Micol Maritan, Sira Angela Franchi, Tullio Pozzan, Claudia Lodovichi

J Neurosci. 2011 Jun 8; 31(23): 8395–8405. doi: 10.1523/JNEUROSCI.6722-10.2011

PMCID:: PMC6623327

Abstract Article PDF–2.2M

Select item 63538182.

Epac activation inhibits IL-6-induced cardiac myocyte dysfunction

Huiling Jin, Takayuki Fujita, Meihua Jin, Reiko Kurotani, Yuko Hidaka, Wenqian Cai, Kenji Suita, Rajesh Prajapati, Chen Liang, Yoshiki Ohnuki, Yasumasa Mototani, Masanari Umemura, Utako Yokoyama, Motohiko Sato, Satoshi Okumura, Yoshihiro Ishikawa

J Physiol Sci. 2018 Jan; 68(1): 77–87. Published online 2016 Dec 19. doi: 10.1007/s12576-016-0509-5

Correction in:: J Physiol Sci. 2019 May; 69(3): 557.

PMCID:: PMC6353818

Abstract Article PDF–1.1M

Select item 54147453.

Epac is Required for GLP-1R-Mediated Inhibition of Oxidative Stress and Apoptosis in Cardiomyocytes

Supachoke Mangmool, Piriya Hemplueksa, Warisara Parichatikanond, Nipon Chattipakorn

Mol Endocrinol. 2015 Apr; 29(4): 583–596. Published online 2015 Feb 26. doi: 10.1210/me.2014-1346

PMCID:: PMC5414745

Abstract Article

Select item 43413664.

Epac activation initiates associative odor preference memories in the rat pup

Matthew T. Grimes, Maria Powell, Sandra Mohammed Gutierrez, Andrea Darby-King, Carolyn W. Harley, John H. McLean

Learn Mem. 2015 Feb; 22(2): 74–82. Published online 2015 Feb. doi: 10.1101/lm.037101.114

PMCID:: PMC4341366

Abstract Article PDF–360K

Select item 32460995.

Epac enhances excitation-transcription coupling in cardiac myocytes

Laetitia Pereira, Gema Ruiz-Hurtado, Eric Morel, Anne-Coline Laurent, Mélanie Métrich, Alejandro Domínguez, Sandra Lauton, Alexandre Lucas, Jean-Pierre Benitah, Donald M. Bers, Frank Lezoualc’h, Ana M. Gómez

J Mol Cell Cardiol. Author manuscript; available in PMC 2013 Jan 1.

Published in final edited form as: J Mol Cell Cardiol. 2012 Jan; 52(1): 283–291. Published online 2011 Oct 29. doi: 10.1016/j.yjmcc.2011.10.016

PMCID:: PMC3246099

Abstract Article PDF–1.8M

Select item 29750176.

Cyclic AMP-dependent protein kinase and Epac mediate cyclic AMP responses in pancreatic acini

Anamika Chaudhuri, Sohail Z. Husain, Thomas R. Kolodecik, Wayne M. Grant, Fred S. Gorelick

Am J Physiol Gastrointest Liver Physiol. Author manuscript; available in PMC 2010 Nov 7.

Published in final edited form as: Am J Physiol Gastrointest Liver Physiol. 2007 May; 292(5): G1403–G1410. Published online 2007 Jan 18. doi: 10.1152/ajpgi.00478.2005

PMCID:: PMC2975017

Abstract Article PDF–1.4M

Select item 27290347.

The cAMP binding protein Epac regulates cardiac myofilament function

Olivier Cazorla, Alexandre Lucas, Florence Poirier, Alain Lacampagne, Frank Lezoualc'h

Proc Natl Acad Sci U S A. 2009 Aug 18; 106(33): 14144–14149. Published online 2009 Aug 6. doi: 10.1073/pnas.0812536106

PMCID:: PMC2729034

Abstract Article PDF–1.3M

Select item 23909188.

Effects of prostaglandin E₂ on the subcellular localization of Epac-1 and Rap1 proteins during Fcγ receptor mediated phagocytosis in alveolar macrophages

Thomas G. Brock, Carlos H. Serezani, Jennifer K. Carstens, Marc Peters-Golden, David M. Aronoff

Exp Cell Res. Author manuscript; available in PMC 2008 May 21.

Published in final edited form as: Exp Cell Res. 2008 Jan 15; 314(2): 255–263. Published online 2007 Oct 23. doi: 10.1016/j.yexcr.2007.10.011

PMCID:: PMC2390918

Abstract Article PDF–677K

Select item 22770539.

A critical role of the cAMP sensor Epac in switching protein kinase signalling in prostaglandin E2-induced potentiation of P2X3 receptor currents in inflamed rats

Congying Wang, Yanping Gu, Guang-Wen Li, Li-Yen Mae Huang

J Physiol. 2007 Oct 1; 584(Pt 1): 191–203. Published online 2007 Aug 16. doi: 10.1113/jphysiol.2007.135616

PMCID:: PMC2277053

Abstract Article PDF–645K

Select item 166497710.

Exposure to cAMP and β-adrenergic stimulation recruits Ca_V3 T-type channels in rat chromaffin cells through Epac cAMP-receptor proteins

M Novara, P Baldelli, D Cavallari, V Carabelli, A Giancippoli, E Carbone

J Physiol. 2004 Jul 15; 558(Pt 2): 433–449. Published online 2004 May 14. doi: 10.1113/jphysiol.2004.061184

PMCID:: PMC1664977

Abstract Article PDF–438K

Select item 128940911.

Epac Activation Converts cAMP from a Proliferative into a Differentiation Signal in PC12 Cells

Simone Kiermayer, Ricardo M. Biondi, Jochen Imig, Guido Plotz, Jörg Haupenthal, Stefan Zeuzem, Albrecht Piiper

Mol Biol Cell. 2005 Dec; 16(12): 5639–5648. doi: 10.1091/mbc.E05-05-0432

PMCID:: PMC1289409

Abstract Article PDF–373K

Select item 934409012.

Unraveling the role of Epac1‐SOCS3 signaling in the development of neonatal‐CRD‐induced visceral hypersensitivity in rats

Si‐Ting Huang, Bin‐Bin Chen, Zhi‐Jing Song, Hui‐Li Tang, Rong Hua, Yong‐Mei Zhang

CNS Neurosci Ther. 2022 Sep; 28(9): 1393–1408. Published online 2022 Jun 15. doi: 10.1111/cns.13880

PMCID:: PMC9344090

Abstract Article PDF–26M

Select item 667077913.

Application of an Epac Activator Enhances Neurotransmitter Release at Excitatory Central Synapses

Isabella Gekel, Erwin Neher

J Neurosci. 2008 Aug 6; 28(32): 7991–8002. doi: 10.1523/JNEUROSCI.0268-08.2008

PMCID:: PMC6670779

Abstract Article PDF–915K

Select item 666610914.

cAMP-Dependent Axon Guidance Is Distinctly Regulated by Epac and Protein Kinase A

Andrew J. Murray, Steven J. Tucker, Derryck A. Shewan

J Neurosci. 2009 Dec 9; 29(49): 15434–15444. doi: 10.1523/JNEUROSCI.3071-09.2009

PMCID:: PMC6666109

Abstract Article PDF–2.2M

Select item 546772815.

Kv7 channel activation underpins EPAC-dependent relaxations of rat arteries

Jennifer B Stott, Vincenzo Barrese, Iain A Greenwood

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2017 Jun 12.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2016 Dec; 36(12): 2404–2411. Published online 2016 Oct 27. doi: 10.1161/ATVBAHA.116.308517