PMC Links for Gene (Select 5921) - PMC

Whitney L. Wooderchak-Donahue, Peter Johnson, Jamie McDonald, Francine Blei, Alejandro Berenstein, Michelle Sorscher, Jennifer Mayer, Angela E. Scheuerle, Tracey Lewis, J. Fredrik Grimmer, Gresham T. Richter, Marcie A. Steeves, Angela E. Lin, David A. Stevenson, Pinar Bayrak-Toydemir

Eur J Hum Genet. 2018 Oct; 26(10): 1521–1536. Published online 2018 Jun 11. doi: 10.1038/s41431-018-0196-1

PMCID:: PMC6138627

Abstract Article PDF–1.4M

Select item 57664144.

Somatic Second Hit Mutation of RASA1 in Vascular Endothelial Cells in Capillary Malformation-Arteriovenous Malformation

Philip E. Lapinski, Abbas Doosti, Valerie Salato, Paula North, Patricia E. Burrows, Philip D. King

Eur J Med Genet. Author manuscript; available in PMC 2019 Jan 1.

Published in final edited form as: Eur J Med Genet. 2018 Jan; 61(1): 11–16. Published online 2017 Oct 9. doi: 10.1016/j.ejmg.2017.10.004

PMCID:: PMC5766414

Abstract Article PDF–488K

Select item 51346955.

RNA-binding protein QKI-5 inhibits the proliferation of clear cell renal cell carcinoma via post-transcriptional stabilization of RASA1 mRNA

Rui-Li Zhang, Jun-Ping Yang, Li-Xia Peng, Li-Sheng Zheng, Ping Xie, Meng-Yao Wang, Yun Cao, Zhi-Ling Zhang, Fang-Jian Zhou, Chao-Nan Qian, Yong-Xing Bao

Cell Cycle. 2016; 15(22): 3094–3104. Published online 2016 Oct 21. doi: 10.1080/15384101.2016.1235103

PMCID:: PMC5134695

Abstract Article PDF–1.0M

Select item 39453466.

Functional Cross-talk between Ras and Rho Pathways: A Ras-SPECIFIC GTPase-ACTIVATING PROTEIN (p120RasGAP) COMPETITIVELY INHIBITS THE RhoGAP ACTIVITY OF DELETED IN LIVER CANCER (DLC) TUMOR SUPPRESSOR BY MASKING THE CATALYTIC ARGININE FINGER

Mamta Jaiswal, Radovan Dvorsky, Ehsan Amin, Sarah L. Risse, Eyad K. Fansa, Si-Cai Zhang, Mohamed S. Taha, Aziz R. Gauhar, Saeideh Nakhaei-Rad, Claus Kordes, Katja T. Koessmeier, Ion C. Cirstea, Monilola A. Olayioye, Dieter Häussinger, Mohammad R. Ahmadian

J Biol Chem. 2014 Mar 7; 289(10): 6839–6849. Published online 2014 Jan 17. doi: 10.1074/jbc.M113.527655

PMCID:: PMC3945346

Abstract Article PDF–2.2M

Select item 34583707.

Ras and GTPase-activating protein (GAP) drive GTP into a precatalytic state as revealed by combining FTIR and biomolecular simulations

Till Rudack, Fei Xia, Jürgen Schlitter, Carsten Kötting, Klaus Gerwert

Proc Natl Acad Sci U S A. 2012 Sep 18; 109(38): 15295-15300. Published online 2012 Sep 4. doi: 10.1073/pnas.1204333109

PMCID:: PMC3458370

Abstract Article PDF–923K

Select item 27557628.

Determination of Ras-GTP and Ras-GDP in patients with acute myelogenous leukemia (AML), myeloproliferative syndrome (MPS), juvenile myelomonocytic leukemia (JMML), acute lymphocytic leukemia (ALL), and malignant lymphoma: assessment of mutational and indirect activation

D. Raepple, F. von Lintig, T. Zemojtel, M. Duchniewicz, A. Jung, M. Lübbert, G. R. Boss, J. S. Scheele

Ann Hematol. 2009 Apr; 88(4): 319–324. Published online 2008 Sep 11. doi: 10.1007/s00277-008-0593-6

PMCID:: PMC2755762

Abstract Article PDF–173K

Select item 3949419.

Solution structure of GAP SH3 domain by 1H NMR and spatial arrangement of essential Ras signaling-involved sequence.

Y S Yang, C Garbay, M Duchesne, F Cornille, N Jullian, N Fromage, B Tocque, B P Roques

EMBO J. 1994 Mar 15; 13(6): 1270–1279. doi: 10.1002/j.1460-2075.1994.tb06379.x

PMCID:: PMC394941

Summary Page Browse PDF–1.9M

Select item 1080993610.

p120 RasGAP and ZO-2 are essential for Hippo signaling and tumor-suppressor function mediated by p190A RhoGAP

Hanyue Ouyang, Shuang Wu, Wangji Li, Michael J. Grey, Wenchao Wu, Steen H. Hansen

Cell Rep. Author manuscript; available in PMC 2024 Jan 25.

Published in final edited form as: Cell Rep. 2023 Dec 26; 42(12): 113486. Published online 2023 Nov 22. doi: 10.1016/j.celrep.2023.113486

PMCID:: PMC10809936

Abstract Article PDF–3.8M

Select item 1029209111.

Mutations in chromatin modifier and Ephrin signaling genes in Vein of Galen malformation

Daniel Duran, Xue Zeng, Sheng Chih Jin, Jungmin Choi, Carol Nelson-Williams, Bogdan Yatsula, Jonathan Gaillard, Charuta Gavankar Furey, Qiongshi Lu, Andrew T. Timberlake, Weilai Dong, Michelle A. Sorscher, Erin Loring, Jennifer Klein, August Allocco, Ava Hunt, Sierra Conine, Jason K. Karimy, Mark W. Youngblood, Jinwei Zhang, Michael L. DiLuna, Charles C. Matouk, Shrikant Mane, Irina R. Tikhonova, Christopher Castaldi, Francesc López-Giráldez, James Knight, Shozeb Haider, Mariya Soban, Seth L. Alper, Masaki Komiyama, Andrew F. Ducruet, Joseph M. Zabramski, Alan Dardik, Brian P. Walcott, Christopher J. Stapleton, Beverly Aagaard-Kienitz, Georges Rodesch, Eric Jackson, Edward R. Smith, Darren B. Orbach, Alejandro Berenstein, Kaya Bilguvar, Miikka Vikkula, Murat Gunel, Richard P. Lifton, Kristopher T. Kahle

Neuron. Author manuscript; available in PMC 2023 Jun 26.

Published in final edited form as: Neuron. 2019 Feb 6; 101(3): 429–443.e4. Published online 2018 Dec 18. doi: 10.1016/j.neuron.2018.11.041

PMCID:: PMC10292091

Abstract Article PDF–1.8M

Select item 858007512.

Assessing the association of common genetic variants in EPHB4 and RASA1 with phenotype severity in familial cerebral cavernous malformation

Foram Choksi, Shantel Weinsheimer, Jeffrey Nelson, Ludmila Pawlikowska, Christine K. Fox, Atif Zafar, Marc C. Mabray, Joseph Zabramski, Amy Akers, Blaine L. Hart, Leslie Morrison, Charles E. McCulloch, Helen Kim

Mol Genet Genomic Med. 2021 Oct; 9(10): e1794. Published online 2021 Sep 7. doi: 10.1002/mgg3.1794

PMCID:: PMC8580075

Abstract Article PDF–464K

Select item 826504313.

The long noncoding RNA MEG3 regulates Ras-MAPK pathway through RASA1 in trophoblast and is associated with unexplained recurrent spontaneous abortion

Jun Zhang, Xinqiong Liu, Yali Gao

Mol Med. 2021; 27: 70. Published online 2021 Jul 8. doi: 10.1186/s10020-021-00337-9

PMCID:: PMC8265043

Abstract Article PDF–7.8M

Select item 647212014.

MicroRNA-4530 suppresses cell proliferation and induces apoptosis by targeting RASA1 in human umbilical vein endothelial cells

Li Jing, Hong Li, Tao Zhang, Jianxin Lu, Lianjin Zhong

Mol Med Rep. 2019 May; 19(5): 3393–3402. Published online 2019 Mar 1. doi: 10.3892/mmr.2019.10000

PMCID:: PMC6472120

Abstract Article PDF–1.5M

Select item 644021515.

RASA1 and NF1 are preferentially co-mutated and define a distinct genetic subset of smoking-associated non-small cell lung carcinomas sensitive to MEK inhibition.

Takuo Hayashi, Patrice Desmeules, Roger S. Smith, Alexander Drilon, Romel Somwar, Marc Ladanyi

Clin Cancer Res. Author manuscript; available in PMC 2019 Mar 29.

Published in final edited form as: Clin Cancer Res. 2018 Mar 15; 24(6): 1436–1447. Published online 2017 Nov 10. doi: 10.1158/1078-0432.CCR-17-2343

PMCID:: PMC6440215

Abstract Article PDF–1.5M

Select item 636570416.

MicroRNA-21 regulates the biological behavior of esophageal squamous cell carcinoma by targeting RASA1

Xiaohua Chen, Sina Cai, Baoxia Li, Xiaona Zhang, Wenhui Li, Henglun Liang, Xiaolong Cao, Liping Wang, Ziqing Wu

Oncol Rep. 2019 Mar; 41(3): 1627–1637. Published online 2018 Dec 19. doi: 10.3892/or.2018.6944

PMCID:: PMC6365704

Abstract Article PDF–1.5M

Select item 555276217.

MicroRNA-132 promotes fibroblast migration via regulating RAS p21 protein activator 1 in skin wound healing

Xi Li, Dongqing Li, Jakob D. Wikstrom, Andor Pivarcsi, Enikö Sonkoly, Mona Ståhle, Ning Xu Landén

Sci Rep. 2017; 7: 7797. Published online 2017 Aug 10. doi: 10.1038/s41598-017-07513-0

PMCID:: PMC5552762

Abstract Article PDF–3.5M

Select item 502967118.

Inactivation of RASA1 promotes melanoma tumorigenesis via R-Ras activation

Hyeran Sung, Krishna L. Kanchi, Xue Wang, Kristen S. Hill, Jane L. Messina, Ji-Hyun Lee, Youngchul Kim, Nathan D. Dees, Li Ding, Jamie K. Teer, Shengyu Yang, Amod A. Sarnaik, Vernon K. Sondak, James J. Mulé, Richard K. Wilson, Jeffrey S. Weber, Minjung Kim

Oncotarget. 2016 Apr 26; 7(17): 23885–23896. Published online 2016 Mar 16. doi: 10.18632/oncotarget.8127

PMCID:: PMC5029671

Abstract Article PDF–9.7M

Select item 450810819.

Genetic Variants Associated with Port-Wine Stains

Alice Frigerio, Karol Wright, Whitney Wooderchak-Donahue, Oon T. Tan, Rebecca Margraf, David A. Stevenson, J. Fredrik Grimmer, Pinar Bayrak-Toydemir

PLoS One. 2015; 10(7): e0133158. Published online 2015 Jul 20. doi: 10.1371/journal.pone.0133158

PMCID:: PMC4508108

Abstract Article PDF–3.8M

Select item 449398620.

Hypoxia-inducible MiR-182 promotes angiogenesis by targeting RASA1 in hepatocellular carcinoma

Chengli Du, Xiaoyu Weng, Wendi Hu, Zhen Lv, Heng Xiao, Chaofeng Ding, Owusu-anash K. Gyabaah, Haiyang Xie, Lin Zhou, Jian Wu, Shusen Zheng

J Exp Clin Cancer Res. 2015; 34(1): 67. Published online 2015 Jun 28. doi: 10.1186/s13046-015-0182-1

PMCID:: PMC4493986

Abstract Article PDF–1.7M

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