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Items: 1 to 20 of 445

1.
Acquired mutations in BAX confer resistance to BH3-mimetic therapy in acute myeloid leukemia
Donia M. Moujalled, Fiona C. Brown, Chong Chyn Chua, Michael A. Dengler, Giovanna Pomilio, Natasha S. Anstee, Veronique Litalien, Ella Thompson, Thomas Morley, Sarah MacRaild, Ing S. Tiong, Rhiannon Morris, Karen Dun, Adrian Zordan, Jaynish Shah, Sebastien Banquet, Ensar Halilovic, Erick Morris, Marco J. Herold, Guillaume Lessene, Jerry M. Adams, David C. S. Huang, Andrew W. Roberts, Piers Blombery, Andrew H. Wei
Blood. 2023 Feb 9; 141(6): 634–644. Published online 2022 Oct 14. doi: 10.1182/blood.2022016090
Correction in:
Blood. 2023 Aug 3; 142(5): 494.
PMCID:
PMC10651776
AbstractArticle
2.
The conformational stability of pro-apoptotic BAX is dictated by discrete residues of the protein core
Noah B. Bloch, Thomas E. Wales, Michelle S. Prew, Hannah R. Levy, John R. Engen, Loren D. Walensky
Nat Commun. 2021; 12: 4932. Published online 2021 Aug 13. doi: 10.1038/s41467-021-25200-7
PMCID:
PMC8363748
AbstractArticlePDF–1.9M
3.
Characteristics of intracellular propagation of mitochondrial BAX recruitment during apoptosis
Joshua A. Grosser, Margaret E. Maes, Robert W. Nickells
Apoptosis. Author manuscript; available in PMC 2022 Feb 1.
Published in final edited form as: Apoptosis. 2021 Feb; 26(1-2): 132–145. Published online 2021 Jan 11. doi: 10.1007/s10495-020-01654-w
PMCID:
PMC8082518
AbstractArticlePDF–2.0M
4.
Membrane‐dependent amyloid aggregation of human BAX α9 (173–192)
David A. Price, Tayler D. Hill, Kaitlyn A. Hutson, Blaze W. Rightnowar, Sean D. Moran
Protein Sci. 2021 May; 30(5): 1072–1080. Published online 2021 Mar 12. doi: 10.1002/pro.4053
PMCID:
PMC8040860
AbstractArticlePDF–2.5M
5.
A Structural Model for Bax∆2-Mediated Activation of Caspase 8-Dependent Apoptosis
Bing Xie, Qi Yao, Jialing Xiang, David D.L. Minh
Int J Mol Sci. 2020 Aug; 21(15): 5476. Published online 2020 Jul 31. doi: 10.3390/ijms21155476
PMCID:
PMC7432750
AbstractArticlePDF–4.3M
6.
Site-Dependent Cysteine Lipidation Potentiates the Activation of Proapoptotic BAX
Daniel T. Cohen, Thomas E. Wales, Matthew W. McHenry, John R. Engen, Loren D. Walensky
Cell Rep. Author manuscript; available in PMC 2020 Jul 8.
Published in final edited form as: Cell Rep. 2020 Mar 10; 30(10): 3229–3239.e6. doi: 10.1016/j.celrep.2020.02.057
PMCID:
PMC7343539
AbstractArticlePDF–1.9M
7.
Humanin induces conformational changes in the apoptosis regulator BAX and sequesters it into fibers, preventing mitochondrial outer-membrane permeabilization
Daniel L. Morris, David W. Kastner, Sabrina Johnson, Marie-Paule Strub, Yi He, Christopher K. E. Bleck, Duck-Yeon Lee, Nico Tjandra
J Biol Chem. 2019 Dec 13; 294(50): 19055–19065. Published online 2019 Nov 5. doi: 10.1074/jbc.RA119.011297
PMCID:
PMC6916494
AbstractArticlePDF–3.2M
8.
The inhibition of Bax activation-induced apoptosis by RasGRP2 via R-Ras-PI3K-Akt signaling pathway in the endothelial cells
Jun-ichi Takino, Takuma Sato, Kentaro Nagamine, Takamitsu Hori
Sci Rep. 2019; 9: 16717. Published online 2019 Nov 13. doi: 10.1038/s41598-019-53419-4
PMCID:
PMC6854084
AbstractArticlePDF–2.2M
9.
Completion of BAX recruitment correlates with mitochondrial fission during apoptosis
M. E. Maes, J. A. Grosser, R. L. Fehrman, C. L. Schlamp, R. W. Nickells
Sci Rep. 2019; 9: 16565. Published online 2019 Nov 12. doi: 10.1038/s41598-019-53049-w
PMCID:
PMC6851089
AbstractArticlePDF–6.1M
10.
Neuromuscular Denervation: Bax up against the Wall in Amyotrophic Lateral Sclerosis
Andrew D. Steele, Caroline H. Yi
J Neurosci. 2006 Dec 13; 26(50): 12849–12851. doi: 10.1523/JNEUROSCI.4086-06.2006
PMCID:
PMC6674958
ArticlePDF–275K
11.
Defective Retrotranslocation Causes Loss of Anti-Bax Function in Human Familial Prion Protein Mutants
Julie Jodoin, Stéphanie Laroche-Pierre, Cynthia G. Goodyer, Andréa C. LeBlanc
J Neurosci. 2007 May 9; 27(19): 5081–5091. doi: 10.1523/JNEUROSCI.0957-07.2007
PMCID:
PMC6672383
AbstractArticlePDF–924K
12.
Bax expression and apoptotic cell death in Fanconi anaemia peripheral blood lymphocytes
G. A. Baruque, M. A. Bitencourt, R. Pasquini, M. T. L. Castelo‐Branco, J. C. Llerena, Jr, V. M. Rumjanek
Cell Prolif. 2007 Aug; 40(4): 558–567. Published online 2007 Jul 16. doi: 10.1111/j.1365-2184.2007.00446.x
PMCID:
PMC6495656
AbstractArticlePDF–261K
13.
Molecular and topological reorganizations in mitochondrial architecture interplay during Bax-mediated steps of apoptosis
Nicholas R Ader, Patrick C Hoffmann, Iva Ganeva, Alicia C Borgeaud, Chunxin Wang, Richard J Youle, Wanda Kukulski
eLife. 2019; 8: e40712. Published online 2019 Feb 4. doi: 10.7554/eLife.40712
PMCID:
PMC6361589
AbstractArticlePDF–7.8M
14.
Association of BAX hypermethylation with coronary heart disease is specific to individuals aged over 70
Limei Zhang, Huihui Ji, Yi Huang, Haochang Hu, Bin Li, Yong Yang, Hang Yu, Xiaoying Chen, Wenxia Li, Fang Liu, Shi Wang, Chunming Wang, Ke Chen, Yingchun Bao, Haibo Liu, Shiwei Duan
Medicine (Baltimore) 2019 Jan; 98(4): e14130. Published online 2019 Jan 25. doi: 10.1097/MD.0000000000014130
PMCID:
PMC6358363
AbstractArticlePDF–580K
15.
Lower expression of Bax predicts poor clinical outcome in patients with glioma after curative resection and radiotherapy/chemotherapy
Pei-Guo Wang, Yu-Ting Li, Yi Pan, Zhen-Zhu Gao, Xu-Wen Guan, Li Jia, Feng-Ting Liu
J Neurooncol. 2019; 141(1): 71–81. Published online 2018 Nov 16. doi: 10.1007/s11060-018-03031-9
PMCID:
PMC6341054
AbstractArticlePDF–1.2M
16.
Expression of Bax/Bcl-2, TGF-β1, and Type III Collagen Fiber in Congenital Muscular Torticollis
Dianguo Li, Kelai Wang, Wei Zhang, Junfeng Wang
Med Sci Monit. 2018; 24: 7869–7874. Published online 2018 Nov 3. doi: 10.12659/MSM.909064
PMCID:
PMC6231324
AbstractArticlePDF–906K
17.
Phosphorylation switches Bax from promoting to inhibiting apoptosis thereby increasing drug resistance
Justin Kale, Ozgur Kutuk, Glauber Costa Brito, Tallulah S Andrews, Brian Leber, Anthony Letai, David W Andrews
EMBO Rep. 2018 Sep; 19(9): e45235. Published online 2018 Jul 10. doi: 10.15252/embr.201745235
PMCID:
PMC6123645
AbstractArticlePDF–2.4M
18.
Prognostic value and susceptibility of BAX rs4645878 polymorphism in cancer: A systematic review and meta-analysis
Ye Feng, Xianglei Chen, Yi Zheng, Qiao Liu, Haiwen Chen, Yuanhua Cai, Lixia Cao, Xiaolin Lai, Lili Pan, Yang Li, Shao-Yuan Wang
Medicine (Baltimore) 2018 Jul; 97(29): e11591. Published online 2018 Jul 20. doi: 10.1097/MD.0000000000011591
PMCID:
PMC6086507
AbstractArticlePDF–792K
19.
The pro-apoptotic BAX protein influences cell growth and differentiation from the nucleus in healthy interphasic cells
Stéphanie Brayer, Audrey Joannes, Madeleine Jaillet, Elisa Gregianin, Souhir Mahmoudi, Joëlle Marchal Sommé, Aurélie Fabre, Pierre Mordant, Aurélie Cazes, Bruno Crestani, Arnaud A. Mailleux
Cell Cycle. 2017; 16(21): 2108–2118. Published online 2017 Sep 21. doi: 10.1080/15384101.2017.1371882
PMCID:
PMC5731416
AbstractArticlePDF–1.2M
20.
Apoptotic Bax at Oxidatively Stressed Mitochondrial Membranes: Lipid Dynamics and Permeabilization
Artur Peter Günther Dingeldein, Šárka Pokorná, Martin Lidman, Tobias Sparrman, Radek Šachl, Martin Hof, Gerhard Gröbner
Biophys J. 2017 May 23; 112(10): 2147–2158. Published online 2017 May 23. doi: 10.1016/j.bpj.2017.04.019
PMCID:
PMC5444002
AbstractArticlePDF–1.4M

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