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Select item 84106791.

TACI haploinsufficiency protects against BAFF-driven humoral autoimmunity in mice

Holly M. Jacobs, Tanvi Arkatkar, Samuel W. Du, Nicole E. Scharping, Jonathan Woods, Quan-Zhen Li, Kelly L. Hudkins, Charles E. Alpers, David J. Rawlings, Shaun W. Jackson

Eur J Immunol. Author manuscript; available in PMC 2022 Sep 1.

Published in final edited form as: Eur J Immunol. 2021 Sep; 51(9): 2225–2236. Published online 2021 Jun 27. doi: 10.1002/eji.202149244

PMCID:: PMC8410679

Abstract Article PDF–1.0M

Select item 84100862.

TNFRSF13B polymorphisms counter microbial adaptation to enteric IgA

Jeffrey L. Platt, Mayara Garcia de Mattos Barbosa, Daniel Huynh, Adam R. Lefferts, Juhi Katta, Cyra Kharas, Peter Freddolino, Christine M. Bassis, Christiane Wobus, Raif Geha, Richard Bram, Gabriel Nunez, Nobuhiko Kamada, Marilia Cascalho

JCI Insight. 2021 Jul 22; 6(14): e148208. Published online 2021 Jul 22. doi: 10.1172/jci.insight.148208

PMCID:: PMC8410086

Abstract Article PDF–2.7M

Select item 62379153.

TACI Contributes to Plasmodium yoelii Host Resistance by Controlling T Follicular Helper Cell Response and Germinal Center Formation

Marcela Parra, Jiyeon Yang, Megan Weitner, Steven Derrick, Amy Yang, Thomas Schmidt, Balwan Singh, Alberto Moreno, Mustafa Akkoyunlu

Front Immunol. 2018; 9: 2612. Published online 2018 Nov 9. doi: 10.3389/fimmu.2018.02612

PMCID:: PMC6237915

Abstract Article PDF–2.4M

Select item 60544304.

TACI-Deficient Macrophages Protect Mice Against Metaflammation and Obesity-Induced Dysregulation of Glucose Homeostasis

Lunhua Liu, Karen Etsuko Inouye, Windy Rose Allman, Adam Steven Coleman, Shafiuddin Siddiqui, Gökhan Siddik Hotamisligil, Mustafa Akkoyunlu

Diabetes. 2018 Aug; 67(8): 1589–1603. Published online 2018 Jun 5. doi: 10.2337/db17-1089

PMCID:: PMC6054430

Abstract Article PDF–2.1M

Select item 45228035.

TACI deficiency leads to alternatively activated macrophage phenotype and susceptibility to Leishmania infection

Windy R. Allman, Ranadhir Dey, Lunhua Liu, Shafiuddin Siddiqui, Adam S. Coleman, Parna Bhattacharya, Masahide Yano, Kadriye Uslu, Kazuyo Takeda, Hira L. Nakhasi, Mustafa Akkoyunlu

Proc Natl Acad Sci U S A. 2015 Jul 28; 112(30): E4094–E4103. Published online 2015 Jul 13. doi: 10.1073/pnas.1421580112

PMCID:: PMC4522803

Abstract Article PDF–1.4M

Select item 43472536.

TACI deficiency enhances antibody avidity and clearance of an intestinal pathogen

Shoichiro Tsuji, Lucas Stein, Nobuhiko Kamada, Gabriel Nuñez, Richard Bram, Bruce A. Vallance, Ana E. Sousa, Jeffrey L. Platt, Marilia Cascalho

J Clin Invest. 2014 Nov 3; 124(11): 4857–4866. Published online 2014 Oct 1. doi: 10.1172/JCI74428

PMCID:: PMC4347253

Abstract Article PDF–1.1M

Select item 32284997.

TACI deficiency impairs sustained Blimp-1 expression in B cells decreasing long-lived plasma cells in the bone marrow

Shoichiro Tsuji, Catarina Cortesão, Richard J. Bram, Jeffrey L. Platt, Marilia Cascalho

Blood. 2011 Nov 24; 118(22): 5832–5839. Prepublished online 2011 Oct 7. doi: 10.1182/blood-2011-05-353961

PMCID:: PMC3228499

Abstract Article

Select item 31954698.

Protective antiviral antibody responses in a mouse model of influenza virus infection require TACI

Amaya I. Wolf, Krystyna Mozdzanowska, William J. Quinn, III, Michele Metzgar, Katie L. Williams, Andrew J. Caton, Eric Meffre, Richard J. Bram, Loren D. Erickson, David Allman, Michael P. Cancro, Jan Erikson

J Clin Invest. 2011 Oct 3; 121(10): 3954–3964. Published online 2011 Sep 1. doi: 10.1172/JCI57362

PMCID:: PMC3195469

Abstract Article PDF–1.6M

Select item 21935349.

Maturation of Marginal Zone and Follicular B Cells Requires B Cell Activating Factor of the Tumor Necrosis Factor Family and Is Independent of B Cell Maturation Antigen

Pascal Schneider, Hisakazu Takatsuka, Anne Wilson, Fabienne Mackay, Aubry Tardivel, Susanne Lens, Teresa G. Cachero, Daniela Finke, Friedrich Beermann, Jürg Tschopp

J Exp Med. 2001 Dec 3; 194(11): 1691–1698. doi: 10.1084/jem.194.11.1691

PMCID:: PMC2193534

Abstract Article PDF–309K

Select item 685018610.

TACI expression and plasma cell differentiation are impaired in the absence of functional IκBNS

Sharesta Khoenkhoen, Elina Erikson, Monika Ádori, Julian M Stark, Jean L Scholz, Michael P Cancro, Gabriel K Pedersen, Gunilla B Karlsson Hedestam

Immunol Cell Biol. 2019 May-Jun; 97(5): 485–497. Published online 2019 Jan 30. doi: 10.1111/imcb.12228

PMCID:: PMC6850186

Abstract Article PDF–2.2M

Select item 577800111.

Delayed onset of autoreactive antibody production and M2-skewed macrophages contribute to improved survival of TACI deficient MRL-Fas/Lpr mouse

Lunhua Liu, Windy Rose Allman, Adam Steven Coleman, Kazuyo Takeda, Tsai-Lien Lin, Mustafa Akkoyunlu

Sci Rep. 2018; 8: 1308. Published online 2018 Jan 22. doi: 10.1038/s41598-018-19827-8

PMCID:: PMC5778001

Abstract Article PDF–6.7M

Select item 533744812.

Heterozygosity for TACI A144E causes haploinsufficiency and pneumococcal susceptibility in mice

Haifa H. Jabara, John J. Lee, Erin Janssen, Sumana Ullas, Kyriaki Liadaki, Lilit Garibyan, Halli Benson, Tatyana Sannikova, Richard Bram, Lennart Hammarstrom, Anthony C. Cruz, Richard Siegel, John Manis, Richard Malley, Raif S. Geha

J Allergy Clin Immunol. Author manuscript; available in PMC 2018 Apr 1.

Published in final edited form as: J Allergy Clin Immunol. 2017 Apr; 139(4): 1293–1301.e4. Published online 2016 Sep 5. doi: 10.1016/j.jaci.2016.07.028

PMCID:: PMC5337448

Abstract Article PDF–1.1M

Select item 504606013.

Increased expression of TACI on NOD B cells results in germinal centre reaction anomalies, enhanced plasma cell differentiation and immunoglobulin production

Viqar S. Banday, Radha Thyagarajan, Mia Sundström, Kristina Lejon

Immunology. 2016 Nov; 149(3): 297–305. Published online 2016 Aug 23. doi: 10.1111/imm.12651

PMCID:: PMC5046060

Abstract Article PDF–825K

Select item 486862514.

BAFF promotes autoantibody production via TACI-dependent activation of transitional B cells

Holly M. Jacobs, Christopher D. Thouvenel, Sarah Leach, Tanvi Arkatkar, Genita Metzler, Nicole E. Scharping, Nikita S. Kolhatkar, David J. Rawlings, Shaun W. Jackson

J Immunol. Author manuscript; available in PMC 2017 May 1.

Published in final edited form as: J Immunol. 2016 May 1; 196(9): 3525–3531. Published online 2016 Mar 28. doi: 10.4049/jimmunol.1600017

PMCID:: PMC4868625

Abstract Article PDF–1.5M

Select item 438197015.

Effect of TACI Signaling on Humoral Immunity and Autoimmune Diseases

Yi Zhang, Jun Li, Ya-Min Zhang, Xiao-Ming Zhang, Juan Tao

J Immunol Res. 2015; 2015: 247426. Published online 2015 Mar 17. doi: 10.1155/2015/247426

PMCID:: PMC4381970

Abstract Article PDF–1.0M

Select item 274584516.

The murine equivalent of the A181E TACI mutation associated with common variable immunodeficiency severely impairs B-cell function

John J. Lee, Ingrid Rauter, Lilit Garibyan, Esra Ozcan, Tatyana Sannikova, Stacey R. Dillon, Anthony C. Cruz, Richard M. Siegel, Richard Bram, Haifa Jabara, Raif S. Geha

Blood. 2009 Sep 10; 114(11): 2254–2262. Prepublished online 2009 Jul 15. doi: 10.1182/blood-2008-11-189720

PMCID:: PMC2745845

Abstract Article

Select item 274414117.

Tonic B cell antigen receptor signals supply an NF-κB substrate for prosurvival BLyS signaling

Jason E Stadanlick, Mary Kaileh, Fredrick G Karnell, Jean L Scholz, Juli P Miller, William J Quinn, III, Randall J Brezski, Laura S Treml, Kimberly A Jordan, John G Monroe, Ranjan Sen, Michael P Cancro

Nat Immunol. Author manuscript; available in PMC 2009 Sep 15.

Published in final edited form as: Nat Immunol. 2008 Dec; 9(12): 1379–1387. Published online 2008 Nov 2. doi: 10.1038/ni.1666

PMCID:: PMC2744141

Abstract Article PDF–2.7M

Select item 269346218.

TACI drives plasma cell differentiation in LPS activated B cells

Esra Ozcan, Lilit Garibyan, John Jhe-Yun Lee, Richard J. Bram, Kong-Peng Lam, Raif S. Geha

J Allergy Clin Immunol. Author manuscript; available in PMC 2010 Jun 1.

Published in final edited form as: J Allergy Clin Immunol. 2009 Jun; 123(6): 1277–86.e5. Published online 2009 May 8. doi: 10.1016/j.jaci.2009.03.019

PMCID:: PMC2693462

Abstract Article PDF–1.7M

Select item 212161219.

Transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI) enhances CD40 driven plasma cell differentiation

Emanuela Castigli, Stephen A. Wilson, Abdallah Elkhal, Esra Ozcan, Lilit Garibyan, Raif S. Geha

J Allergy Clin Immunol. Author manuscript; available in PMC 2007 Dec 7.

Published in final edited form as: J Allergy Clin Immunol. 2007 Oct; 120(4): 885–891. Published online 2007 Aug 8. doi: 10.1016/j.jaci.2007.06.012

PMCID:: PMC2121612

Abstract Article PDF–772K

Select item 189575420.

Selective activation of TACI by syndecan-2

Daniela Bischof, Sherine F. Elsawa, George Mantchev, Juhan Yoon, Grace E. Michels, Allan Nilson, Shari L. Sutor, Jeffrey L. Platt, Stephen M. Ansell, Gotz von Bulow, Richard J. Bram

Blood. 2006 Apr 15; 107(8): 3235–3242. Prepublished online 2005 Dec 15. doi: 10.1182/blood-2005-01-0256