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Items: 1 to 20 of 180

1.
Raptor mediates the selective inhibitory effect of cardamonin on RRAGC-mutant B cell lymphoma
Ying Liu, Yanting Zhu, Huajiao Chen, Jintuo Zhou, Peiguang Niu, Daohua Shi
BMC Complement Med Ther. 2023; 23: 336. Published online 2023 Sep 26. doi: 10.1186/s12906-023-04166-7
PMCID:
PMC10521446
AbstractArticlePDF–1.7M
2.
Raptor localization predicts prognosis and tamoxifen response in estrogen receptor-positive breast cancer
Josefine Bostner, Anya Alayev, Adi Y. Berman, Tommy Fornander, Bo Nordenskjöld, Marina K. Holz, Olle Stål
Breast Cancer Res Treat. 2018; 168(1): 17–27. Published online 2017 Nov 11. doi: 10.1007/s10549-017-4508-x
PMCID:
PMC5847064
AbstractArticlePDF–1.3M
3.
RAPTOR up-regulation contributes to resistance of renal cancer cells to PI3K-mTOR inhibition
Philip Earwaker, Caroline Anderson, Frances Willenbrock, Adrian L. Harris, Andrew S. Protheroe, Valentine M. Macaulay
PLoS One. 2018; 13(2): e0191890. Published online 2018 Feb 1. doi: 10.1371/journal.pone.0191890
PMCID:
PMC5794101
AbstractArticlePDF–6.4M
4.
Genetic Variation in the Raptor Gene Is Associated With Overweight But Not Hypertension in American Men of Japanese Ancestry
Brian J. Morris, Bruce A. Carnes, Randi Chen, Timothy A. Donlon, Qimei He, John S. Grove, Kamal H. Masaki, Ayako Elliott, Donald C. Willcox, Richard Allsopp, Bradley J. Willcox
Am J Hypertens. 2015 Apr; 28(4): 508–517. Published online 2014 Sep 22. doi: 10.1093/ajh/hpu188
PMCID:
PMC4425837
AbstractArticlePDF–5.2M
5.
Allele-Specific Down-Regulation of RPTOR Expression Induced by Retinoids Contributes to Climate Adaptations
Chang Sun, Catherine Southard, David B. Witonsky, Ralf Kittler, Anna Di Rienzo
PLoS Genet. 2010 Oct; 6(10): e1001178. Published online 2010 Oct 28. doi: 10.1371/journal.pgen.1001178
PMCID:
PMC2965758
AbstractArticlePDF–1.6M
6.
A rare Asian founder polymorphism of Raptor may explain the high prevalence of Moyamoya disease among East Asians and its low prevalence among Caucasians
Wanyang Liu, Hirokuni Hashikata, Kayoko Inoue, Norio Matsuura, Yohei Mineharu, Hatasu Kobayashi, Ken-ichiro Kikuta, Yasushi Takagi, Toshiaki Hitomi, Boris Krischek, Li-Ping Zou, Fang Fang, Roman Herzig, Jeong-Eun Kim, Hyun-Seung Kang, Chang-Wan Oh, David-Alexandre Tregouet, Nobuo Hashimoto, Akio Koizumi
Environ Health Prev Med. 2010 Mar; 15(2): 94–104. Published online 2009 Nov 19. doi: 10.1007/s12199-009-0116-7
PMCID:
PMC2824103
AbstractArticlePDF–1005K
7.
Raptor and rictor expression in patients with human papillomavirus-related oropharyngeal squamous cell carcinoma
Shunsuke Kondo, Hitoshi Hirakawa, Taro Ikegami, Takayuki Uehara, Shinya Agena, Jin Uezato, Hidetoshi Kinjyo, Noritomo Kise, Yukashi Yamashita, Katsunori Tanaka, Narumi Hasegawa, Asanori Kiyuna, Hiroyuki Maeda, Mikio Suzuki, Akira Gahana
BMC Cancer. 2021; 21: 87. Published online 2021 Jan 22. doi: 10.1186/s12885-021-07794-9
PMCID:
PMC7821513
AbstractArticlePDF–5.3M
8.
RAPTOR promotes colorectal cancer proliferation by inducing mTORC1 and upregulating ribosome assembly factor URB1
Tao Wang, Wei‐Sheng Zhang, Zheng‐Xia Wang, Zhi‐Wei Wu, Bin‐Bin Du, Lai‐Yuan Li, Yi‐Feng Chen, Xiong‐Fei Yang, Xiang‐Yong Hao, Tian‐Kang Guo
Cancer Med. 2020 Feb; 9(4): 1529–1543. Published online 2019 Dec 30. doi: 10.1002/cam4.2810
Correction in:
Cancer Med. 2021 Oct; 10(20): 7442–7443.
PMCID:
PMC7013072
AbstractArticlePDF–3.5M
9.
Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A
Sung Min Son, So Jung Park, Huikyong Lee, Farah Siddiqi, Jong Eun Lee, Fiona M. Menzies, David C. Rubinsztein
Cell Metab. 2019 Jan 8; 29(1): 192–201.e7. doi: 10.1016/j.cmet.2018.08.013
PMCID:
PMC6331339
AbstractArticlePDF–4.9M
10.
Up-regulation of the mammalian target of rapamycin complex 1 subunit Raptor by aldosterone induces abnormal pulmonary artery smooth muscle cell survival patterns to promote pulmonary arterial hypertension
Reza Aghamohammadzadeh, Ying-Yi Zhang, Thomas E. Stephens, Elena Arons, Paula Zaman, Kevin J. Polach, Majed Matar, Lai-Ming Yung, Paul B. Yu, Frederick P. Bowman, Alexander R. Opotowsky, Aaron B. Waxman, Joseph Loscalzo, Jane A. Leopold, Bradley A. Maron
FASEB J. 2016 Jul; 30(7): 2511–2527. Published online 2016 Mar 22. doi: 10.1096/fj.201500042
Correction in:
FASEB J. 2024 Jan 31; 38(2): e23438.
PMCID:
PMC4904292
AbstractArticle
11.
Seasonal effects of the UCP3 and the RPTOR gene polymorphisms on obesity traits in Japanese adults
Kazuhiro Nakayama, Hiroshi Miyashita, Sadahiko Iwamoto
J Physiol Anthropol. 2014; 33(1): 38. Published online 2014 Dec 22. doi: 10.1186/1880-6805-33-38
PMCID:
PMC4347541
AbstractArticlePDF–438K
12.
Mitotic Raptor Promotes mTORC1 Activity, G2/M Cell Cycle Progression, and Internal Ribosome Entry Site-Mediated mRNA Translation
Francisco Ramírez-Valle, Michelle L. Badura, Steve Braunstein, Manisha Narasimhan, Robert J. Schneider
Mol Cell Biol. 2010 Jul; 30(13): 3151–3164. Published online 2010 May 3. doi: 10.1128/MCB.00322-09
PMCID:
PMC2897579
AbstractArticlePDF–2.2M
13.
Characterization of a novel splicing variant in the RAPTOR gene
Chang Sun, Catherine Southard, Anna Di Rienzo
Mutat Res. Author manuscript; available in PMC 2009 Aug 11.
Published in final edited form as: Mutat Res. 2009 Mar 9; 662(1-2): 88–92. doi: 10.1016/j.mrfmmm.2009.01.001
PMCID:
PMC2724650
AbstractArticlePDF–1.5M
14.
Human cytomegalovirus infection alters the substrate specificities and rapamycin sensitivities of raptor- and rictor-containing complexes
Sagar B. Kudchodkar, Yongjun Yu, Tobi G. Maguire, James C. Alwine
Proc Natl Acad Sci U S A. 2006 Sep 19; 103(38): 14182–14187. Published online 2006 Sep 7. doi: 10.1073/pnas.0605825103
PMCID:
PMC1599931
AbstractArticlePDF–1.1M
15.
Association of PI3K/AKT/mTOR pathway autophagy-related gene polymorphisms with pulmonary tuberculosis susceptibility in a Chinese population
Juan He, Shengyuan Liu, Xujun Guo, Fan Zhang, Yuzheng Fan, Lijuan Wu, Howard Eugene Takiff, Yashuang Zhao
Rev Soc Bras Med Trop. 2023; 56: e0104-2023. Published online 2023 Jul 24. doi: 10.1590/0037-8682-0104-2023
PMCID:
PMC10367219
AbstractArticlePDF–1.1M
16.
Leucine regulates autophagy via acetylation of the mTORC1 component raptor
Sung Min Son, So Jung Park, Eleanna Stamatakou, Mariella Vicinanza, Fiona M. Menzies, David C. Rubinsztein
Nat Commun. 2020; 11: 3148. Published online 2020 Jun 19. doi: 10.1038/s41467-020-16886-2
PMCID:
PMC7305105
AbstractArticlePDF–4.3M
17.
Macrophage Raptor Deficiency-Induced Lysosome Dysfunction Exacerbates Nonalcoholic Steatohepatitis
Wenli Liu, Chenji Ye, Qian Cheng, Xuejiao Zhang, Liu Yao, Qi Li, Jing Huang, Yajin Liu, Zhengsheng Zou, Hua Wang, Jun Yan, Yi Zhu, Chunjiong Wang, Ding Ai
Cell Mol Gastroenterol Hepatol. 2019; 7(1): 211–231. Published online 2018 Sep 19. doi: 10.1016/j.jcmgh.2018.09.011
PMCID:
PMC6282883
AbstractArticlePDF–7.1M
18.
DNA methylation array analysis identifies breast cancer associated RPTOR, MGRN1 and RAPSN hypomethylation in peripheral blood DNA
Qiuqiong Tang, Tim Holland-Letz, Alla Slynko, Katarina Cuk, Frederik Marme, Sarah Schott, Jörg Heil, Bin Qu, Michael Golatta, Melanie Bewerunge-Hudler, Christian Sutter, Harald Surowy, Barbara Wappenschmidt, Rita Schmutzler, Markus Hoth, Peter Bugert, Claus R. Bartram, Christof Sohn, Andreas Schneeweiss, Rongxi Yang, Barbara Burwinkel
Oncotarget. 2016 Sep 27; 7(39): 64191–64202. Published online 2016 Aug 26. doi: 10.18632/oncotarget.11640
PMCID:
PMC5325435
AbstractArticlePDF–2.7M
19.
RPTOR, a novel target of miR-155, elicits a fibrotic phenotype of cystic fibrosis lung epithelium by upregulating CTGF
Motohiro Tsuchiya, Swathi Kalurupalle, Parameet Kumar, Sarani Ghoshal, Yongqing Zhang, Elin Lehrmann, Kevin G. Becker, Myriam Gorospe, Roopa Biswas
RNA Biol. 2016 Sep; 13(9): 837–847. Published online 2016 Jun 10. doi: 10.1080/15476286.2016.1197484
PMCID:
PMC5013987
AbstractArticlePDF–995K
20.
mTORC1 directly phosphorylates and activates ERa upon estrogen stimulation
A Alayev, R S Salamon, S M Berger, N S Schwartz, R Cuesta, R B Snyder, M K Holz
Oncogene. Author manuscript; available in PMC 2016 Jul 8.
Published in final edited form as: Oncogene. 2016 Jul 7; 35(27): 3535–3543. Published online 2015 Nov 2. doi: 10.1038/onc.2015.414
PMCID:
PMC4853282
AbstractArticlePDF–1.4M

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