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Select item 95411931.

PSMC1 variant causes a novel neurological syndrome

Sarit Aharoni, Regina Proskorovski‐Ohayon, Ramesh Kumar Krishnan, Yuval Yogev, Ohad Wormser, Noam Hadar, Anna Bakhrat, Ismael Alshafee, Maya Gombosh, Nadav Agam, Libe Gradstein, Zamir Shorer, Raz Zarivach, Marina Eskin‐Schwartz, Uri Abdu, Ohad S. Birk

Clin Genet. 2022 Oct; 102(4): 324–332. Published online 2022 Aug 3. doi: 10.1111/cge.14195

PMCID:: PMC9541193

Abstract Article PDF–6.8M

Select item 88065382.

Low expression of TCP1 (T-Complex 1) and PSMC1 (Proteasome 26S subunit, ATPase 1) in heterotopic ossification during ankylosing spondylitis

Xiao-lin Zhong, Bang-Ping Qian, Ji-chen Huang, Shi-zhou Zhao, Yao Li, Yong Qiu

Bioengineered. 2021; 12(1): 7459–7469. Published online 2021 Oct 6. doi: 10.1080/21655979.2021.1975981

PMCID:: PMC8806538

Abstract Article PDF–2.7M

Select item 3020573.

Regulation of the 26S proteasome by adenovirus E1A

Andrew S. Turnell, Roger J.A. Grand, Carlos Gorbea, Xian Zhang, Wenlan Wang, Joe S. Mymryk, Phillip H. Gallimore

EMBO J. 2000 Sep 1; 19(17): 4759–4773. doi: 10.1093/emboj/19.17.4759

PMCID:: PMC302057

Abstract Article PDF–1.0M

Select item 66705644.

Depletion of 26S Proteasomes in Mouse Brain Neurons Causes Neurodegeneration and Lewy-Like Inclusions Resembling Human Pale Bodies

Lynn Bedford, David Hay, Anny Devoy, Simon Paine, Des G. Powe, Rashmi Seth, Trevor Gray, Ian Topham, Kevin Fone, Nooshin Rezvani, Maureen Mee, Tim Soane, Robert Layfield, Paul W. Sheppard, Ted Ebendal, Dmitry Usoskin, James Lowe, R. John Mayer

J Neurosci. 2008 Aug 13; 28(33): 8189–8198. doi: 10.1523/JNEUROSCI.2218-08.2008

PMCID:: PMC6670564

Abstract Article PDF–630K

Select item 35078215.

HUWE1 and TRIP12 Collaborate in Degradation of Ubiquitin-Fusion Proteins and Misframed Ubiquitin

Esben G. Poulsen, Cornelia Steinhauer, Michael Lees, Anne-Marie Lauridsen, Lars Ellgaard, Rasmus Hartmann-Petersen

PLoS One. 2012; 7(11): e50548. Published online 2012 Nov 27. doi: 10.1371/journal.pone.0050548

PMCID:: PMC3507821

Abstract Article PDF–769K

Select item 49483136.

Structure of the human 26S proteasome at a resolution of 3.9 Å

Andreas Schweitzer, Antje Aufderheide, Till Rudack, Florian Beck, Günter Pfeifer, Jürgen M. Plitzko, Eri Sakata, Klaus Schulten, Friedrich Förster, Wolfgang Baumeister

Proc Natl Acad Sci U S A. 2016 Jul 12; 113(28): 7816–7821. Published online 2016 Jun 24. doi: 10.1073/pnas.1608050113

PMCID:: PMC4948313

Abstract Article PDF–1.8M

Select item 47523497.

TOPORS, a Dual E3 Ubiquitin and Sumo1 Ligase, Interacts with 26 S Protease Regulatory Subunit 4, Encoded by the PSMC1 Gene

Barbara Czub, Amna Z. Shah, Giovanna Alfano, Przemysław M. Kruczek, Christina F. Chakarova, Shomi S. Bhattacharya

PLoS One. 2016; 11(2): e0148678. Published online 2016 Feb 12. doi: 10.1371/journal.pone.0148678

PMCID:: PMC4752349

Abstract Article PDF–2.8M

Select item 34293518.

Cancer vulnerabilities unveiled by genomic loss

Deepak Nijhawan, Travis I. Zack, Yin Ren, Matthew R. Strickland, Rebecca Lamothe, Steven E. Schumacher, Aviad Tsherniak, Henrike C. Besche, Joseph Rosenbluh, Shyemaa Shehata, Glenn S. Cowley, Barbara A. Weir, Alfred L. Goldberg, Jill P. Mesirov, David E. Root, Sangeeta N. Bhatia, Rameen Beroukhim, William C. Hahn

Cell. Author manuscript; available in PMC 2013 Aug 17.

Published in final edited form as: Cell. 2012 Aug 17; 150(4): 842–854. doi: 10.1016/j.cell.2012.07.023

PMCID:: PMC3429351

Abstract Article PDF–3.5M

Select item 28984449.

Caspase-3 Cleaves Specific 19 S Proteasome Subunits in Skeletal Muscle Stimulating Proteasome Activity

Xiaonan H. Wang, Liping Zhang, William E. Mitch, Joseph M. LeDoux, Junping Hu, Jie Du

J Biol Chem. 2010 Jul 9; 285(28): 21249–21257. Published online 2010 Apr 27. doi: 10.1074/jbc.M109.041707

PMCID:: PMC2898444

Abstract Article PDF–1.6M

Select item 275719210.

Subcomplexes of PA700, the 19 S Regulator of the 26 S Proteasome, Reveal Relative Roles of AAA Subunits in 26 S Proteasome Assembly and Activation and ATPase Activity

David Thompson, Kevin Hakala, George N. DeMartino

J Biol Chem. 2009 Sep 11; 284(37): 24891–24903. Published online 2009 Jul 9. doi: 10.1074/jbc.M109.023218

PMCID:: PMC2757192

Abstract Article PDF–2.0M

Select item 275571111.

Hypoxia-inducible Factor Prolyl-4-hydroxylase PHD2 Protein Abundance Depends on Integral Membrane Anchoring of FKBP38

Sandra Barth, Frank Edlich, Utta Berchner-Pfannschmidt, Silke Gneuss, Günther Jahreis, Philippe A. Hasgall, Joachim Fandrey, Roland H. Wenger, Gieri Camenisch

J Biol Chem. 2009 Aug 21; 284(34): 23046–23058. Published online 2009 Jun 22. doi: 10.1074/jbc.M109.032631

PMCID:: PMC2755711

Abstract Article PDF–3.5M

Select item 297857312.

ASK1 Negatively Regulates the 26 S Proteasome

Ji Won Um, Eunju Im, Joongkyu Park, Yohan Oh, Boram Min, Hyun Jung Lee, Jong Bok Yoon, Kwang Chul Chung

J Biol Chem. 2010 Nov 19; 285(47): 36434–36446. Published online 2010 Sep 15. doi: 10.1074/jbc.M110.133777

PMCID:: PMC2978573

Abstract Article PDF–2.8M

Select item 51883213.

A complex between peptide:N-glycanase and two proteasome-linked proteins suggests a mechanism for the degradation of misfolded glycoproteins

Samiksha Katiyar, Guangtao Li, William J. Lennarz

Proc Natl Acad Sci U S A. 2004 Sep 21; 101(38): 13774–13779. Published online 2004 Sep 9. doi: 10.1073/pnas.0405663101

PMCID:: PMC518832

Abstract Article PDF–463K

Select item 356155314.

ATP Binding by Proteasomal ATPases Regulates Cellular Assembly and Substrate-induced Functions of the 26 S Proteasome

Young-Chan Kim, Xiaohua Li, David Thompson, George N. DeMartino

J Biol Chem. 2013 Feb 1; 288(5): 3334–3345. Published online 2012 Dec 4. doi: 10.1074/jbc.M112.424788

PMCID:: PMC3561553

Abstract Article PDF–2.0M

Select item 314362915.

C Termini of Proteasomal ATPases Play Nonequivalent Roles in Cellular Assembly of Mammalian 26 S Proteasome

Young-Chan Kim, George N. DeMartino

J Biol Chem. 2011 Jul 29; 286(30): 26652–26666. Published online 2011 May 31. doi: 10.1074/jbc.M111.246793

PMCID:: PMC3143629

Abstract Article PDF–6.1M

Select item 663342816.

Parkin Directly Modulates 26S Proteasome Activity

Ji Won Um, Eunju Im, Hyun Jung Lee, Boram Min, Lang Yoo, Jiho Yoo, Hermann Lübbert, Christine Stichel-Gunkel, Hyun-Soo Cho, Jong Bok Yoon, Kwang Chul Chung

J Neurosci. 2010 Sep 1; 30(35): 11805–11814. doi: 10.1523/JNEUROSCI.2862-09.2010

PMCID:: PMC6633428

Abstract Article PDF–1.3M

Select item 405161817.

The degradation of p53 and its major E3 ligase Mdm2 is differentially dependent on the proteasomal ubiquitin receptor S5a

A Sparks, S Dayal, J Das, P Robertson, S Menendez, M K Saville

Oncogene. 2014 Sep 18; 33(38): 4685–4696. Published online 2013 Oct 14. doi: 10.1038/onc.2013.413

PMCID:: PMC4051618

Abstract Article PDF–2.8M

Select item 108429918.

Proteasomal ATPase-Associated Factor 1 Negatively Regulates Proteasome Activity by Interacting with Proteasomal ATPases

Yoon Park, Yong-Pil Hwang, Jong-Sik Lee, Sang-Hyun Seo, Sungjoo Kim Yoon, Jong-Bok Yoon

Mol Cell Biol. 2005 May; 25(9): 3842–3853. doi: 10.1128/MCB.25.9.3842-3853.2005

PMCID:: PMC1084299

Abstract Article PDF–808K

Select item 436725819.

The E3 Ubiquitin Ligase Parkin Is Recruited to the 26 S Proteasome via the Proteasomal Ubiquitin Receptor Rpn13

Miguel A. Aguileta, Jelena Korac, Thomas M. Durcan, Jean-François Trempe, Michael Haber, Kalle Gehring, Suzanne Elsasser, Oliver Waidmann, Edward A. Fon, Koraljka Husnjak

J Biol Chem. 2015 Mar 20; 290(12): 7492–7505. Published online 2015 Feb 9. doi: 10.1074/jbc.M114.614925