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Select item 71908241.

Human β-defensin 3 gene modification promotes the osteogenic differentiation of human periodontal ligament cells and bone repair in periodontitis

Lingjun Li, Han Jiang, Rixin Chen, Jing Zhou, Yin Xiao, Yangheng Zhang, Fuhua Yan

Int J Oral Sci. 2020; 12: 13. Published online 2020 Apr 29. doi: 10.1038/s41368-020-0078-6

PMCID:: PMC7190824

Abstract Article PDF–4.7M

Select item 69345052.

Human β-defensin-3 reduces excessive autophagy in intestinal epithelial cells and in experimental necrotizing enterocolitis

Liping Chen, Zhibao Lv, Zhimei Gao, Guijie Ge, Xueli Wang, Junmei Zhou, Qingfeng Sheng

Sci Rep. 2019; 9: 19890. Published online 2019 Dec 27. doi: 10.1038/s41598-019-56535-3

PMCID:: PMC6934505

Abstract Article PDF–2.3M

Select item 55479793.

Expression and antimicrobial character of cells transfected with human β-defensin-3 against periodontitis-associated microbiota in vitro

Minwen Zhu, Bo Miao, Jianhua Zhu, Haiyan Wang, Zengtong Zhou

Mol Med Rep. 2017 Sep; 16(3): 2455–2460. Published online 2017 Jul 4. doi: 10.3892/mmr.2017.6913

PMCID:: PMC5547979

Abstract Article PDF–1.1M

Select item 53427864.

Human beta-defensin 3 contributes to the carcinogenesis of cervical cancer via activation of NF-κB signaling

Dan Xu, Bing Zhang, Chongbing Liao, Wei Zhang, Weijia Wang, Ying Chang, Yongping Shao

Oncotarget. 2016 Nov 15; 7(46): 75902–75913. Published online 2016 Oct 4. doi: 10.18632/oncotarget.12426

PMCID:: PMC5342786

Abstract Article PDF–8.8M

Select item 49546835.

Effects of Genetically Modified Milk Containing Human Beta-Defensin-3 on Gastrointestinal Health of Mice

Xin Chen, Yange Yang, Zhaopeng Shi, Ming-Qing Gao, Yong Zhang

PLoS One. 2016; 11(7): e0159700. Published online 2016 Jul 20. doi: 10.1371/journal.pone.0159700

PMCID:: PMC4954683

Abstract Article PDF–7.3M

Select item 46852726.

An ancestral host defence peptide within human β-defensin 3 recapitulates the antibacterial and antiviral activity of the full-length molecule

Ersilia Nigro, Irene Colavita, Daniela Sarnataro, Olga Scudiero, Gerardo Zambrano, Vincenzo Granata, Aurora Daniele, Alfonso Carotenuto, Stefania Galdiero, Veronica Folliero, Massimiliano Galdiero, Richard A. Urbanowicz, Jonathan K. Ball, Francesco Salvatore, Antonello Pessi

Sci Rep. 2015; 5: 18450. Published online 2015 Dec 21. doi: 10.1038/srep18450

PMCID:: PMC4685272

Abstract Article PDF–1.2M

Select item 46006747.

Cytotoxicity of HBD3 for dendritic cells, normal human epidermal keratinocytes, hTERT keratinocytes, and primary oral gingival epithelial keratinocytes in cell culture conditions

Nattawut Leelakanok, Carol L. Fischer, Amber M. Bates, Janet M. Guthmiller, Georgia K. Johnson, Aliasger K. Salem, Kim A. Brogden, Nicole K. Brogden

Toxicol Lett. Author manuscript; available in PMC 2016 Dec 3.

Published in final edited form as: Toxicol Lett. 2015 Dec 3; 239(2): 90–96. Published online 2015 Sep 11. doi: 10.1016/j.toxlet.2015.09.006

PMCID:: PMC4600674

Abstract Article PDF–655K

Select item 45543928.

Identification of a cell-penetrating peptide domain from human beta-defensin 3 and characterization of its anti-inflammatory activity

Jue Yeon Lee, Jin Sook Suh, Jung Min Kim, Jeong Hwa Kim, Hyun Jung Park, Yoon Jeong Park, Chong Pyoung Chung

Int J Nanomedicine. 2015; 10: 5423–5434. Published online 2015 Aug 26. doi: 10.2147/IJN.S90014

PMCID:: PMC4554392

Abstract Article PDF–2.5M

Select item 41006599.

Human β-defensin-3 induction in H pylori-infected gastric mucosal tissues

K Kawauchi, A Yagihashi, N Tsuji, N Uehara, D Furuya, D Kobayashi, N Watanabe

World J Gastroenterol. 2006 Sep 28; 12(36): 5793–5797. Published online 2006 Sep 28. doi: 10.3748/wjg.v12.i36.5793

PMCID:: PMC4100659

Abstract Article PDF–915K

Select item 405052210.

Membrane damage and repair in primary monocytes exposed to human β-defensin-3

Anthony B. Lioi, Angel L. Reyes Rodriguez, Nicholas T. Funderburg, Zhimin Feng, Aaron Weinberg, Scott F. Sieg

J Leukoc Biol. 2012 Nov; 92(5): 1083–1091. doi: 10.1189/jlb.0112046

PMCID:: PMC4050522

Abstract Article

Select item 383964511.

Human β defensin-3 induces chemokines from monocytes and macrophages: diminished activity in cells from HIV-infected persons

Velizar Petrov, Nicholas Funderburg, Aaron Weinberg, Scott Sieg

Immunology. 2013 Dec; 140(4): 413–420. Published online 2013 Oct 28. doi: 10.1111/imm.12148

PMCID:: PMC3839645

Abstract Article PDF–447K

Select item 371401312.

Molecular and Functional Analysis of Human β-Defensin 3 Action at Melanocortin Receptors

Matthew A. Nix, Christopher B. Kaelin, Tina Ta, Allison Weis, Gregory J. Morton, Gregory S. Barsh, Glenn L. Millhauser

Chem Biol. Author manuscript; available in PMC 2014 Jun 20.

Published in final edited form as: Chem Biol. 2013 Jun 20; 20(6): 784–795. doi: 10.1016/j.chembiol.2013.04.015

PMCID:: PMC3714013

Abstract Article PDF–1.6M

Select item 348687813.

Human Beta-Defensin 3 Is Up-Regulated in Cutaneous Leprosy Type 1 Reactions

Anna L. Cogen, Stephen L. Walker, Chrissy H. Roberts, Deanna A. Hagge, Kapil D. Neupane, Saraswoti Khadge, Diana N. J. Lockwood

PLoS Negl Trop Dis. 2012 Nov; 6(11): e1869. Published online 2012 Nov 1. doi: 10.1371/journal.pntd.0001869

PMCID:: PMC3486878

Abstract Article PDF–287K

Select item 326342314.

A Worldwide Analysis of Beta-Defensin Copy Number Variation Suggests Recent Selection of a High-Expressing DEFB103 Gene Copy in East Asia

Robert J Hardwick, Lee R Machado, Luciana W Zuccherato, Suzanne Antolinos, Yali Xue, Nyambura Shawa, Robert H Gilman, Lilia Cabrera, Douglas E Berg, Chris Tyler-Smith, Paul Kelly, Eduardo Tarazona-Santos, Edward J Hollox

Hum Mutat. 2011 Jul; 32(7): 743–750. Published online 2011 Mar 8. doi: 10.1002/humu.21491