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Select item 76954101.

Molecular identification of protein kinase C beta in Alzheimer's disease

Zhike Zhou, Fenqin Chen, Shanshan Zhong, Yi Zhou, Rongwei Zhang, Kexin Kang, Xiaoqian Zhang, Ying Xu, Mei Zhao, Chuansheng Zhao

Aging (Albany NY) 2020 Nov 15; 12(21): 21798–21808. Published online 2020 Nov 7. doi: 10.18632/aging.103994

PMCID:: PMC7695410

Abstract Article PDF–1.0M

Select item 72986552.

The Inhibition of Protein Kinase C β Contributes to the Pathogenesis of Preeclampsia by Activating Autophagy

Huanqiang Zhao, Lili Gong, Suwen Wu, Tianrui Jing, Xirong Xiao, Yutong Cui, Huangfang Xu, Huiqing Lu, Yao Tang, Jin Zhang, Qiongjie Zhou, Duan Ma, Xiaotian Li

EBioMedicine. 2020 Jun; 56: 102813. Published online 2020 Jun 13. doi: 10.1016/j.ebiom.2020.102813

PMCID:: PMC7298655

Abstract Article PDF–4.1M

Select item 54693253.

Protein kinase C β inhibits autophagy and sensitizes cervical cancer Hela cells to cisplatin

Na Li, Wei Zhang

Biosci Rep. 2017 Apr 30; 37(2): BSR20160445. Prepublished online 2017 Feb 28. Published online 2017 Mar 27. doi: 10.1042/BSR20160445

PMCID:: PMC5469325

Abstract Article PDF–1.0M

Select item 51799394.

A novel missense variant in PRKCB segregates low-frequency hearing loss in an autosomal dominant family with Meniere’s disease

Carmen Martín-Sierra, Teresa Requena, Lidia Frejo, Steven D. Price, Alvaro Gallego-Martinez, Angel Batuecas-Caletrio, Sofía Santos-Pérez, Andrés Soto-Varela, Anna Lysakowski, Jose A. Lopez-Escamez

Hum Mol Genet. 2016 Aug 15; 25(16): 3407–3415. Published online 2016 Jun 21. doi: 10.1093/hmg/ddw183

PMCID:: PMC5179939

Abstract Article PDF–648K

Select item 49915015.

Protein kinase C beta II suppresses colorectal cancer by regulating IGF-1 mediated cell survival

Catríona M. Dowling, James Phelan, Julia A. Callender, Mary Clare Cathcart, Brian Mehigan, Paul McCormick, Tara Dalton, John C. Coffey, Alexandra C. Newton, Jacintha O'sullivan, Patrick A. Kiely

Oncotarget. 2016 Apr 12; 7(15): 20919–20933. Published online 2016 Mar 14. doi: 10.18632/oncotarget.8062

PMCID:: PMC4991501

Abstract Article PDF–9.0M

Select item 46261746.

Subcellular proteomic approach for identifying the signaling effectors of protein kinase C-β₂ under high glucose conditions in human umbilical vein endothelial cells

MIN ZHANG, FANG SUN, FANGFANG CHEN, BO ZHOU, YAQIAN DUAN, HONG SU, XUEBO LIN

Mol Med Rep. 2015 Nov; 12(5): 7247–7262. Published online 2015 Sep 30. doi: 10.3892/mmr.2015.4403

PMCID:: PMC4626174

Abstract Article PDF–1.3M

Select item 42237167.

Disruption of endothelial adherens junctions by high glucose is mediated by protein kinase C-β–dependent vascular endothelial cadherin tyrosine phosphorylation

Mehran Haidari, Wei Zhang, James T Willerson, Richard AF Dixon

Cardiovasc Diabetol. 2014; 13: 105. Published online 2014 Jul 15. doi: 10.1186/1475-2840-13-105

Correction in:: Cardiovasc Diabetol. 2017; 16: 136.

PMCID:: PMC4223716

Abstract Article PDF–1.3M

Select item 40525348.

Hyperglycaemia promotes human brain microvascular endothelial cell apoptosis via induction of protein kinase C-ß_I and prooxidant enzyme NADPH oxidase

Beili Shao, Ulvi Bayraktutan

Redox Biol. 2014; 2: 694–701. Published online 2014 May 28. doi: 10.1016/j.redox.2014.05.005

PMCID:: PMC4052534

Abstract Article PDF–2.0M

Select item 40045949.

PKCβII acts downstream of chemoattractant receptors and mTORC2 to regulate cAMP production and myosin II activity in neutrophils

Lunhua Liu, Derek Gritz, Carole A. Parent

Mol Biol Cell. 2014 May 1; 25(9): 1446–1457. doi: 10.1091/mbc.E14-01-0037

PMCID:: PMC4004594

Abstract Article PDF–3.0M

Select item 391274010.

A polymorphism in the protein kinase C gene PRKCB is associated with α₂-adrenoceptor-mediated vasoconstriction

Jussi P. Posti, Perttu Salo, Saku Ruohonen, Laura Valve, Mordechai Muszkat, Gbenga G. Sofowora, Daniel Kurnik, C. Michael Stein, Markus Perola, Mika Scheinin, Amir Snapir

Pharmacogenet Genomics. Author manuscript; available in PMC 2014 Mar 1.

Published in final edited form as: Pharmacogenet Genomics. 2013 Mar; 23(3): 127–134. doi: 10.1097/FPC.0b013e32835d247f

PMCID:: PMC3912740

Abstract Article PDF–999K

Select item 385190211.

PKC-β exacerbates in vitro brain barrier damage in hyperglycemic settings via regulation of RhoA/Rho-kinase/MLC2 pathway

Kirtiman Srivastava, Beili Shao, Ulvi Bayraktutan

J Cereb Blood Flow Metab. 2013 Dec; 33(12): 1928–1936. Published online 2013 Aug 21. doi: 10.1038/jcbfm.2013.151

PMCID:: PMC3851902

Abstract Article PDF–674K

Select item 357272512.

Protein Kinase-C Beta Contributes to Impaired Endothelial Insulin Signaling in Humans with Diabetes Mellitus

Corey E Tabit, Sherene M Shenouda, Monica Holbrook, Jessica L Fetterman, Soroosh Kiani, Alissa A Frame, Matthew A Kluge, Aaron Held, Mustali Dohadwala, Noyan Gokce, Melissa Farb, James Rosenzweig, Neil Ruderman, Joseph A Vita, Naomi M Hamburg

Circulation. Author manuscript; available in PMC 2014 Jan 1.

Published in final edited form as: Circulation. 2013 Jan 1; 127(1): 86–95. Published online 2012 Nov 30. doi: 10.1161/CIRCULATIONAHA.112.127514

PMCID:: PMC3572725

Abstract Article PDF–1.9M

Select item 324613313.

Protein kinase C-beta inhibition induces apoptosis and inhibits cell cycle progression in AIDS-related Non-Hodgkin lymphoma cells

Nakhle S. Saba, Laura S. Levy

J Investig Med. Author manuscript; available in PMC 2013 Jan 1.

Published in final edited form as: J Investig Med. 2012 Jan; 60(1): 29–38. doi: 10.231/JIM.0b013e318237eb55

PMCID:: PMC3246133

Abstract Article PDF–1.1M

Select item 317116814.

Protein Kinase C-β Gene Variants, Pathway Activation, and Enzastaurin Activity in Lung Cancer

Sang-Haak Lee, Tingan Chen, Jun Zhou, Jennifer Hofmann, Gerold Bepler

Clin Lung Cancer. Author manuscript; available in PMC 2011 Sep 12.

Published in final edited form as: Clin Lung Cancer. 2010 May; 11(3): 169–175. doi: 10.3816/CLC.2010.n.021

PMCID:: PMC3171168

Abstract Article PDF–604K

Select item 280129015.

Protein Kinase Cβ Modulates Ligand-induced Cell Surface Death Receptor Accumulation: A MECHANISTIC BASIS FOR ENZASTAURIN-DEATH LIGAND SYNERGY

Xue Wei Meng, Michael P. Heldebrant, Karen S. Flatten, David A. Loegering, Haiming Dai, Paula A. Schneider, Timothy S. Gomez, Kevin L. Peterson, Sergey A. Trushin, Allan D. Hess, B. Douglas Smith, Judith E. Karp, Daniel D. Billadeau, Scott H. Kaufmann

J Biol Chem. 2010 Jan 8; 285(2): 888–902. Published online 2009 Nov 3. doi: 10.1074/jbc.M109.057638

PMCID:: PMC2801290

Abstract Article PDF–4.6M

Select item 148246616.

Chondrocyte cell death mediated by reactive oxygen species-dependent activation of PKC-βI

Marcello DelCarlo, Richard F. Loeser

Am J Physiol Cell Physiol. Author manuscript; available in PMC 2007 Mar 1.

Published in final edited form as: Am J Physiol Cell Physiol. 2006 Mar; 290(3): C802–C811. Published online 2005 Oct 19. doi: 10.1152/ajpcell.00214.2005