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Select item 79208891.

Nucleolar protein 10 (NOP10) predicts poor prognosis in invasive breast cancer

Khloud A. Elsharawy, Maryam Althobiti, Omar J. Mohammed, Abrar I. Aljohani, Michael S. Toss, Andrew R. Green, Emad A. Rakha

Breast Cancer Res Treat. 2021; 185(3): 615–627. Published online 2020 Nov 8. doi: 10.1007/s10549-020-05999-3

PMCID:: PMC7920889

Abstract Article PDF–2.5M

Select item 78620622.

NOP10 predicts lung cancer prognosis and its associated small nucleolar RNAs drive proliferation and migration

Chunhong Cui, Yi Liu, Dennis Gerloff, Christian Rohde, Cornelius Pauli, Marcel Köhn, Danny Misiak, Thomas Oellerich, Schraga Schwartz, Lars-Henning Schmidt, Rainer Wiewrodt, Alessandro Marra, Ludger Hillejan, Frank Bartel, Claudia Wickenhauser, Stefan Hüttelmaier, Stefanie Göllner, Fengbiao Zhou, Bayram Edemir, Carsten Müller-Tidow

Oncogene. 2021; 40(5): 909–921. Published online 2020 Dec 7. doi: 10.1038/s41388-020-01570-y

PMCID:: PMC7862062

Abstract Article PDF–5.7M

Select item 28822273.

Genetic heterogeneity in autosomal recessive dyskeratosis congenita with one subtype due to mutations in the telomerase-associated protein NOP10

Amanda J. Walne, Tom Vulliamy, Anna Marrone, Richard Beswick, Michael Kirwan, Yuka Masunari, Fat-hia Al-Qurashi, Mahmoud Aljurf, Inderjeet Dokal

Hum Mol Genet. Author manuscript; available in PMC 2010 Jun 8.

Published in final edited form as: Hum Mol Genet. 2007 Jul 1; 16(13): 1619–1629. Published online 2007 May 16. doi: 10.1093/hmg/ddm111

PMCID:: PMC2882227

Abstract Article PDF–1.0M

Select item 26487024.

Dyskeratosis congenita mutations in the H/ACA domain of human telomerase RNA affect its assembly into a pre-RNP

Christian Trahan, François Dragon

RNA. 2009 Feb; 15(2): 235–243. doi: 10.1261/rna.1354009

PMCID:: PMC2648702

Abstract Article PDF–1.0M

Select item 3942355.

Architecture and assembly of mammalian H/ACA small nucleolar and telomerase ribonucleoproteins

Chen Wang, U Thomas Meier

EMBO J. 2004 Apr 21; 23(8): 1857–1867. Published online 2004 Mar 25. doi: 10.1038/sj.emboj.7600181

PMCID:: PMC394235

Abstract Article PDF–343K

Select item 14409016.

hNaf1 is required for accumulation of human box H/ACA snoRNPs, scaRNPs, and telomerase

Coralie Hoareau-Aveilla, Mattia Bonoli, Michele Caizergues-Ferrer, Yves Henry

RNA. 2006 May; 12(5): 832–840. doi: 10.1261/rna.2344106

PMCID:: PMC1440901

Abstract Article PDF–752K

Select item 865567.

Human H/ACA Small Nucleolar RNPs and Telomerase Share Evolutionarily Conserved Proteins NHP2 and NOP10

Vanda Pogacic, François Dragon, Witold Filipowicz

Mol Cell Biol. 2000 Dec; 20(23): 9028–9040. doi: 10.1128/mcb.20.23.9028-9040.2000

PMCID:: PMC86556

Abstract Article PDF–4.1M

Select item 73344968.

Pseudouridylation defect due to DKC1 and NOP10 mutations causes nephrotic syndrome with cataracts, hearing impairment, and enterocolitis

Eszter Balogh, Jennifer C. Chandler, Máté Varga, Mona Tahoun, Dóra K. Menyhárd, Gusztáv Schay, Tomas Goncalves, Renáta Hamar, Regina Légrádi, Ákos Szekeres, Olivier Gribouval, Robert Kleta, Horia Stanescu, Detlef Bockenhauer, Andrea Kerti, Hywel Williams, Veronica Kinsler, Wei-Li Di, David Curtis, Maria Kolatsi-Joannou, Hafsa Hammid, Anna Szőcs, Kristóf Perczel, Erika Maka, Gergely Toldi, Florentina Sava, Christelle Arrondel, Magdolna Kardos, Attila Fintha, Ahmed Hossain, Felipe D’Arco, Mario Kaliakatsos, Jutta Koeglmeier, William Mifsud, Mariya Moosajee, Ana Faro, Eszter Jávorszky, Gábor Rudas, Marwa H. Saied, Salah Marzouk, Kata Kelen, Judit Götze, George Reusz, Tivadar Tulassay, François Dragon, Géraldine Mollet, Susanne Motameny, Holger Thiele, Guillaume Dorval, Peter Nürnberg, András Perczel, Attila J. Szabó, David A. Long, Kazunori Tomita, Corinne Antignac, Aoife M. Waters, Kálmán Tory

Proc Natl Acad Sci U S A. 2020 Jun 30; 117(26): 15137–15147. Published online 2020 Jun 17. doi: 10.1073/pnas.2002328117

PMCID:: PMC7334496

Abstract Article PDF–2.2M

Select item 34344839.

An Enhanced H/ACA RNP Assembly Mechanism for Human Telomerase RNA

Emily D. Egan, Kathleen Collins

Mol Cell Biol. 2012 Jul; 32(13): 2428–2439. doi: 10.1128/MCB.00286-12

PMCID:: PMC3434483

Abstract Article PDF–2.5M

Select item 622312910.

Cryo-EM structure of substrate-bound human telomerase holoenzyme

Thi Hoang Duong Nguyen, Jane Tam, Robert A. Wu, Basil J. Greber, Daniel Toso, Eva Nogales, Kathleen Collins

Nature. Author manuscript; available in PMC 2018 Nov 8.

Published in final edited form as: Nature. 2018 May; 557(7704): 190–195. Published online 2018 Apr 25. doi: 10.1038/s41586-018-0062-x

PMCID:: PMC6223129

Abstract Article PDF–5.0M

Select item 117105511.

Nhp2p and Nop10p are essential for the function of H/ACA snoRNPs.

A Henras, Y Henry, C Bousquet-Antonelli, J Noaillac-Depeyre, J P Gélugne, M Caizergues-Ferrer

EMBO J. 1998 Dec 1; 17(23): 7078–7090. doi: 10.1093/emboj/17.23.7078

PMCID:: PMC1171055

Summary PDF–551K

Select item 287652112.

Specificity and Stoichiometry of Subunit Interactions in the Human Telomerase Holoenzyme Assembled In Vivo

Emily D. Egan, Kathleen Collins

Mol Cell Biol. 2010 Jun; 30(11): 2775–2786. Published online 2010 Mar 29. doi: 10.1128/MCB.00151-10

PMCID:: PMC2876521

Abstract Article PDF–2.0M

Select item 818341413.

The deubiquitinase USP36 promotes snoRNP group SUMOylation and is essential for ribosome biogenesis

Hyunju Ryu, Xiao‐Xin Sun, Yingxiao Chen, Yanping Li, Xiaoyan Wang, Roselyn S Dai, Hong‐Ming Zhu, John Klimek, Larry David, Lev M Fedorov, Yoshiaki Azuma, Rosalie C Sears, Mu‐Shui Dai

EMBO Rep. 2021 Jun 4; 22(6): e50684. Published online 2021 Apr 14. doi: 10.15252/embr.202050684

PMCID:: PMC8183414

Abstract Article PDF–2.1M

Select item 291759514.

Purification of Human Telomerase Complexes Identifies Factors Involved in Telomerase Biogenesis and Telomere Length Regulation

Dragony Fu, Kathleen Collins

Mol Cell. Author manuscript; available in PMC 2010 Aug 7.

Published in final edited form as: Mol Cell. 2007 Dec 14; 28(5): 773–785. doi: 10.1016/j.molcel.2007.09.023

PMCID:: PMC2917595

Abstract Article PDF–2.1M

Select item 432914315.

Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1

Adam Freund, Franklin L. Zhong, Andrew S. Venteicher, Zhaojing Meng, Timothy D. Veenstra, Judith Frydman, Steven E. Artandi

Cell. Author manuscript; available in PMC 2015 Dec 4.

Published in final edited form as: Cell. 2014 Dec 4; 159(6): 1389–1403. Published online 2014 Nov 20. doi: 10.1016/j.cell.2014.10.059

PMCID:: PMC4329143

Abstract Article PDF–1.4M

Select item 368073216.

HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment

Dennis Kappei, Falk Butter, Christian Benda, Marion Scheibe, Irena Draškovič, Michelle Stevense, Clara Lopes Novo, Claire Basquin, Masatake Araki, Kimi Araki, Dragomir Blazhev Krastev, Ralf Kittler, Rolf Jessberger, J Arturo Londoño-Vallejo, Matthias Mann, Frank Buchholz

EMBO J. 2013 Jun 12; 32(12): 1681–1701. Published online 2013 May 17. doi: 10.1038/emboj.2013.105

PMCID:: PMC3680732

Abstract Article PDF–1.6M

Select item 349950717.

Nucleolar Protein Trafficking in Response to HIV-1 Tat: Rewiring the Nucleolus

Mohamed Ali Jarboui, Carlo Bidoia, Elena Woods, Barbara Roe, Kieran Wynne, Giuliano Elia, William W. Hall, Virginie W. Gautier

PLoS One. 2012; 7(11): e48702. Published online 2012 Nov 15. doi: 10.1371/journal.pone.0048702

PMCID:: PMC3499507

Abstract Article PDF–1.5M

Select item 846595318.

Interactome Analysis of the Nucleocapsid Protein of SARS-CoV-2 Virus

Xiaoqin Zheng, Zeyu Sun, Liang Yu, Danrong Shi, Miaojin Zhu, Hangping Yao, Lanjuan Li

Pathogens. 2021 Sep; 10(9): 1155. Published online 2021 Sep 8. doi: 10.3390/pathogens10091155

PMCID:: PMC8465953

Abstract Article PDF–1.7M

Select item 702912319.

The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival

Yuanming He, Siyu Wang, Jiefei Tong, Shuoyi Jiang, Ye Yang, Zubin Zhang, Yujia Xu, Yuanying Zeng, Biyin Cao, Michael F. Moran, Xinliang Mao

J Biol Chem. 2020 Feb 14; 295(7): 2084–2096. Published online 2019 Dec 10. doi: 10.1074/jbc.RA119.010724

PMCID:: PMC7029123

Abstract Article PDF–3.6M

Select item 761053520.

PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase

Bikash Adhikari, Jelena Bozilovic, Mathias Diebold, Jessica Denise Schwarz, Julia Hofstetter, Martin Schröder, Marek Wanior, Ashwin Narain, Markus Vogt, Nevenka Dudvarski Stankovic, Apoorva Baluapuri, Lars Schönemann, Lorenz Eing, Pranjali Bhandare, Bernhard Kuster, Andreas Schlosser, Stephanie Heinzlmeir, Christoph Sotriffer, Stefan Knapp, Elmar Wolf

Nat Chem Biol. Author manuscript; available in PMC 2021 Apr 6.

Published in final edited form as: Nat Chem Biol. 2020 Nov 1; 16(11): 1179–1188. Published online 2020 Sep 28. doi: 10.1038/s41589-020-00652-y

PMCID:: PMC7610535

Abstract Article PDF–5.1M

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