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Items: 1 to 20 of 30

1.
The PARL family of mitochondrial rhomboid proteases
R. Blake Hill, Luca Pellegrini
Semin Cell Dev Biol. Author manuscript; available in PMC 2011 Aug 1.
Published in final edited form as: Semin Cell Dev Biol. 2010 Aug; 21(6): 582–592. Published online 2010 Jan 4. doi: 10.1016/j.semcdb.2009.12.011
PMCID:
PMC2908206
AbstractArticlePDF–670K
2.
Genetic Variation in PARL Influences Mitochondrial Content
Joanne E. Curran, Jeremy B.M. Jowett, Lawrence J. Abraham, Luke A. Diepeveen, Katherine S. Elliott, Thomas D. Dyer, Lyndal J. Kerr-Bayles, Matthew P. Johnson, Anthony G. Comuzzie, Eric K. Moses, Ken R. Walder, Gregory R. Collier, John Blangero, Ahmed H. Kissebah
Hum Genet. Author manuscript; available in PMC 2011 Feb 1.
Published in final edited form as: Hum Genet. 2010 Feb; 127(2): 183–190. Published online 2009 Oct 28. doi: 10.1007/s00439-009-0756-0
PMCID:
PMC2829432
AbstractArticlePDF–941K
3.
The PARL Leu262Val is not associated with fasting insulin levels in UK populations
K. A. Fawcett, I. Barroso, N. J. Wareham, J. Luan, H. Syddall, C. Cooper, S. O'Rahilly, I. N. M. Day, M. S. Sandhu, I. Barroso
Diabetologia. Author manuscript; available in PMC 2009 Apr 23.
Published in final edited form as: Diabetologia. 2006 Nov; 49(11): 2649–2652. Published online 2006 Sep 21. doi: 10.1007/s00125-006-0443-9
PMCID:
PMC2672784
AbstractArticlePDF–272K
4.
Phosphorylation and cleavage of presenilin-associated rhomboid-like protein (PARL) promotes changes in mitochondrial morphology
Danny V. Jeyaraju, Liqun Xu, Marie-Claude Letellier, Sirisha Bandaru, Rodolfo Zunino, Eric A. Berg, Heidi M. McBride, Luca Pellegrini
Proc Natl Acad Sci U S A. 2006 Dec 5; 103(49): 18562–18567. Published online 2006 Nov 20. doi: 10.1073/pnas.0604983103
PMCID:
PMC1693702
AbstractArticlePDF–1.3M
5.
Cleavage of mitochondrial homeostasis regulator PGAM5 by the intramembrane protease PARL is governed by transmembrane helix dynamics and oligomeric state
Verena Siebert, Mara Silber, Elena Heuten, Claudia Muhle-Goll, Marius K. Lemberg
J Biol Chem. 2022 Sep; 298(9): 102321. Published online 2022 Jul 31. doi: 10.1016/j.jbc.2022.102321
PMCID:
PMC9436811
AbstractArticlePDF–2.7M
6.
PARL partitions the lipid transfer protein STARD7 between the cytosol and mitochondria
Shotaro Saita, Takashi Tatsuta, Philipp A Lampe, Tim König, Yohsuke Ohba, Thomas Langer
EMBO J. 2018 Feb 15; 37(4): e97909. Published online 2018 Jan 4. doi: 10.15252/embj.201797909
PMCID:
PMC5813258
AbstractArticlePDF–2.0M
7.
Common variants in the PARL and PINK1 genes increase the risk to leprosy in Han Chinese from South China
Dong Wang, Deng-Feng Zhang, Jia-Qi Feng, Guo-Dong Li, Xiao-An Li, Xiu-Feng Yu, Heng Long, Yu-Ye Li, Yong-Gang Yao
Sci Rep. 2016; 6: 37086. Published online 2016 Nov 23. doi: 10.1038/srep37086
PMCID:
PMC5120299
AbstractArticlePDF–962K
8.
Rhomboid Protease PARL Mediates the Mitochondrial Membrane Potential Loss-induced Cleavage of PGAM5
Shiori Sekine, Yusuke Kanamaru, Masato Koike, Ayako Nishihara, Masahiro Okada, Hideyuki Kinoshita, Miki Kamiyama, Junichi Maruyama, Yasuo Uchiyama, Naotada Ishihara, Kohsuke Takeda, Hidenori Ichijo
J Biol Chem. 2012 Oct 5; 287(41): 34635–34645. Published online 2012 Aug 22. doi: 10.1074/jbc.M112.357509
PMCID:
PMC3464569
AbstractArticlePDF–2.3M
9.
Structural and mechanistic basis of Parl activity and regulation
D V Jeyaraju, H M McBride, R B Hill, L Pellegrini
Cell Death Differ. 2011 Sep; 18(9): 1531–1539. Published online 2011 Mar 18. doi: 10.1038/cdd.2011.22
PMCID:
PMC3134571
AbstractArticlePDF–841K
10.
Intramembrane protease PARL defines a negative regulator of PINK1- and PARK2/Parkin-dependent mitophagy
Cathrin Meissner, Holger Lorenz, Beate Hehn, Marius K Lemberg
Autophagy. 2015 Sep; 11(9): 1484–1498. Published online 2015 Jun 23. doi: 10.1080/15548627.2015.1063763
PMCID:
PMC4590680
AbstractArticlePDF–1.3M
11.
ABCC5, a Gene That Influences the Anterior Chamber Depth, Is Associated with Primary Angle Closure Glaucoma
Monisha E. Nongpiur, Chiea Chuen Khor, Hongyan Jia, Belinda K. Cornes, Li-Jia Chen, Chunyan Qiao, K. Saidas Nair, Ching-Yu Cheng, Liang Xu, Ronnie George, Do Tan, Khaled Abu-Amero, Shamira A. Perera, Mineo Ozaki, Takanori Mizoguchi, Yasuo Kurimoto, Sancy Low, Liza-Sharmini A. Tajudin, Ching-Lin Ho, Clement C. Y. Tham, Ileana Soto, Paul T. K. Chew, Hon-Tym Wong, Balekudaru Shantha, Masako Kuroda, Essam A. Osman, Guangxian Tang, Sujie Fan, Hailin Meng, Hua Wang, Bo Feng, Victor H. K. Yong, Serena M. L. Ting, Yang Li, Ya-Xing Wang, Zheng Li, Raghavan Lavanya, Ren-Yi Wu, Ying-Feng Zheng, Daniel H. Su, Seng-Chee Loon, R. Rand Allingham, Michael A. Hauser, Nagaswamy Soumittra, Vedam L. Ramprasad, Naushin Waseem, Azhany Yaakub, Kee-Seng Chia, Govindasamy Kumaramanickavel, Tina T. Wong, Alicia C. How, Tran Nguyen Bich Chau, Cameron P. Simmons, Jin-Xin Bei, Yi-Xin Zeng, Shomi S. Bhattacharya, Mingzhi Zhang, Donald T. Tan, Yik-Ying Teo, Saleh A. Al-Obeidan, Do Nhu Hon, E-Shyong Tai, Seang-Mei Saw, Paul J. Foster, Lingam Vijaya, Jost B. Jonas, Tien-Yin Wong, Simon W. M. John, Chi-Pui Pang, Eranga N. Vithana, Ningli Wang, Tin Aung
PLoS Genet. 2014 Mar; 10(3): e1004089. Published online 2014 Mar 6. doi: 10.1371/journal.pgen.1004089
Correction in:
PLoS Genet. 2014 Apr; 10(4): e1004352.
PMCID:
PMC3945113
AbstractArticlePDF–281K
12.
Hax1 is not a Bcl-2-family-related protein and does not present Omi/HtrA2 to PARL : implications for mitochondrial stress and apoptosis
Danny V. Jeyaraju, Giulia Cisbani, Olga M. De Brito, Eugene V. Koonin, Luca Pellegrini
Cell Death Differ. Author manuscript; available in PMC 2015 Jan 21.
Published in final edited form as: Cell Death Differ. 2009 Dec; 16(12): 1622–1629. Published online 2009 Aug 14. doi: 10.1038/cdd.2009.110
PMCID:
PMC4300852
AbstractArticlePDF–1.3M
13.
PINK1 cleavage at position A103 by the mitochondrial protease PARL
Emma Deas, Helene Plun-Favreau, Sonia Gandhi, Howard Desmond, Svend Kjaer, Samantha H.Y. Loh, Alan E.M. Renton, Robert J. Harvey, Alexander J. Whitworth, L. Miguel Martins, Andrey Y. Abramov, Nicholas W. Wood
Hum Mol Genet. 2011 Mar 1; 20(5): 867–879. Published online 2010 Dec 6. doi: 10.1093/hmg/ddq526
PMCID:
PMC3033179
AbstractArticlePDF–459K
14.
PHB2 (prohibitin 2) promotes PINK1-PRKN/Parkin-dependent mitophagy by the PARL-PGAM5-PINK1 axis
Chaojun Yan, Longlong Gong, Li Chen, Meng Xu, Hussein Abou-Hamdan, Mingliang Tang, Laurent Désaubry, Zhiyin Song
Autophagy. 2020; 16(3): 419–434. Published online 2019 Jun 16. doi: 10.1080/15548627.2019.1628520
PMCID:
PMC6999623
AbstractArticlePDF–5.5M
15.
Evaluation of nine candidate genes in patients with normal tension glaucoma: a case control study
Christiane Wolf, Eugen Gramer, Bertram Müller-Myhsok, Francesca Pasutto, Eva Reinthal, Bernd Wissinger, Nicole Weisschuh
BMC Med Genet. 2009; 10: 91. Published online 2009 Sep 15. doi: 10.1186/1471-2350-10-91
PMCID:
PMC2751751
AbstractArticlePDF–249K
16.
Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment
Andrew W Greene, Karl Grenier, Miguel A Aguileta, Stephanie Muise, Rasoul Farazifard, M Emdadul Haque, Heidi M McBride, David S Park, Edward A Fon
EMBO Rep. 2012 Apr; 13(4): 378–385. Published online 2012 Feb 21. doi: 10.1038/embor.2012.14
PMCID:
PMC3321149
AbstractArticlePDF–1.0M
17.
CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1
Dongbao Li, Yuhong Wang, Chao Dong, Tao Chen, Anqi Dong, Jiayu Ren, Weikang Li, Gege Shu, Jiaoyang Yang, Wenhao Shen, Lei Qin, Lin Hu, Jin Zhou
Oncogene. 2023; 42(2): 83–98. Published online 2022 Nov 12. doi: 10.1038/s41388-022-02537-x
PMCID:
PMC9816059
AbstractArticlePDF–7.6M
18.
Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma
Tatenda Mahlokozera, Bhuvic Patel, Hao Chen, Patrick Desouza, Xuan Qu, Diane D. Mao, Daniel Hafez, Wei Yang, Rukayat Taiwo, Mounica Paturu, Afshin Salehi, Amit D. Gujar, Gavin P. Dunn, Nima Mosammaparast, Allegra A. Petti, Hiroko Yano, Albert H. Kim
Nat Commun. 2021; 12: 6321. Published online 2021 Nov 3. doi: 10.1038/s41467-021-26653-6
PMCID:
PMC8566473
AbstractArticlePDF–2.7M
19.
Genetic Variants in Nuclear-Encoded Mitochondrial Genes Influence AIDS Progression
Sher L. Hendrickson, James A. Lautenberger, Leslie Wei Chinn, Michael Malasky, Efe Sezgin, Lawrence A. Kingsley, James J. Goedert, Gregory D. Kirk, Edward D. Gomperts, Susan P. Buchbinder, Jennifer L. Troyer, Stephen J. O'Brien
PLoS One. 2010; 5(9): e12862. Published online 2010 Sep 21. doi: 10.1371/journal.pone.0012862
PMCID:
PMC2943476
AbstractArticlePDF–461K
20.
The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery
Ramesh Kumar, Román González-Prieto, Zhenyu Xiao, Matty Verlaan-de Vries, Alfred C. O. Vertegaal
Nat Commun. 2017; 8: 1809. Published online 2017 Nov 27. doi: 10.1038/s41467-017-01900-x
PMCID:
PMC5703878
AbstractArticlePDF–3.7M

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