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Select item 111600471.

Reduction of human T‐cell leukemia virus type‐1 infection in mice lacking nuclear factor‐κB‐inducing kinase

Takayuki Nitta, Masakazu Tanaka, Binlian Sun, Eiji Sugihara, Mako Kimura, Yuhei Kamada, Hideto Takahashi, Shuji Hanai, Shi‐Wen Jiang, Jun–ichi Fujisawa, Masanao Miwa

Cancer Sci. 2008 May; 99(5): 872–878. Published online 2008 Feb 28. doi: 10.1111/j.1349-7006.2008.00766.x

PMCID:: PMC11160047

Abstract Article PDF–115K

Select item 101516882.

Inhibition of non-canonical NF-κB signaling suppresses periodontal inflammation and bone loss

Tsukasa Aoki, Fumitaka Hiura, Aonan Li, Nan Yang, Nana Takakura-Hino, Satoru Mukai, Miho Matsuda, Fusanori Nishimura, Eijiro Jimi

Front Immunol. 2023; 14: 1179007. Published online 2023 Apr 18. doi: 10.3389/fimmu.2023.1179007

PMCID:: PMC10151688

Abstract Article PDF–8.9M

Select item 72025443.

Expression of Nik-related kinase in smooth muscle cells attenuates vascular inflammation and intimal hyperplasia

Yi-Jhu Lu, Yee-Jee Jan, Bor-Sheng Ko, Shu-Man Liang, Lujen Chen, Chih-Cheng Wu, Chih-Hui Chin, Cheng-Chin Kuo, Shaw-Fang Yet, Jun-Yang Liou

Aging (Albany NY) 2020 Apr 30; 12(8): 7511–7533. Published online 2020 Apr 24. doi: 10.18632/aging.103104

PMCID:: PMC7202544

Abstract Article PDF–2.8M

Select item 71686244.

Map3k14 as a Regulator of Innate and Adaptive Immune Response during Acute Viral Infection

Thamer A. Hamdan, Hilal Bhat, Lamin B. Cham, Tom Adomati, Judith Lang, Fanghui Li, Ali Murtaza, Cornelia Hardt, Philipp A. Lang, Vikas Duhan, Karl S. Lang

Pathogens. 2020 Feb; 9(2): 96. Published online 2020 Feb 4. doi: 10.3390/pathogens9020096

PMCID:: PMC7168624

Abstract Article PDF–3.5M

Select item 62994255.

Islet α-cell Inflammation Induced By NF-κB inducing kinase (NIK) Leads to Hypoglycemia, Pancreatitis, Growth Retardation, and Postnatal Death in Mice

Xinzhi Li, Linna Jia, Xiaoyue Chen, Ying Dong, Xiaomeng Ren, Yuefan Dong, Ying Chen, Liwei Xie, Ming Liu, Chiyo Shiota, George K. Gittes, Liangyou Rui, Zheng Chen

Theranostics. 2018; 8(21): 5960–5971. Published online 2018 Nov 13. doi: 10.7150/thno.28960

PMCID:: PMC6299425

Abstract Article PDF–2.2M

Select item 58178916.

Constitutive activation of NIK impairs the self-renewal of hematopoietic stem/progenitor cells and induces bone marrow failure

Yan Xiu, Wingel y. Xue, Allyn Lambertz, Mariah Leidinger, Katherine Gibson-Corley, Chen Zhao

Stem Cells. Author manuscript; available in PMC 2018 Mar 1.

Published in final edited form as: Stem Cells. 2017 Mar; 35(3): 777–786. Published online 2016 Nov 2. doi: 10.1002/stem.2523

PMCID:: PMC5817891

Abstract Article PDF–1.5M

Select item 57696077.

Noncanonical NF-κB signaling and the essential kinase NIK modulate crucial features associated with eosinophilic esophagitis pathogenesis

Kristin Eden, Daniel E. Rothschild, Dylan K. McDaniel, Bettina Heid, Irving C. Allen

Dis Model Mech. 2017 Dec 1; 10(12): 1517–1527. doi: 10.1242/dmm.030767

PMCID:: PMC5769607

Abstract Article

Select item 54764858.

Thymic NF-κB-inducing Kinase (NIK) Regulates CD4+ T Cell-elicited Liver Injury and Fibrosis in Mice

Hong Shen, Liang Sheng, Yi Xiong, Yeung-Hyen Kim, Lin Jiang, Zheng Chen, Yong Liu, Kalyani Pyaram, Cheong-Hee Chang, Liangyou Rui

J Hepatol. Author manuscript; available in PMC 2018 Jul 1.

Published in final edited form as: J Hepatol. 2017 Jul; 67(1): 100–109. Published online 2017 Mar 6. doi: 10.1016/j.jhep.2017.02.025

PMCID:: PMC5476485

Abstract Article PDF–1.7M

Select item 51159169.

NFκB-inducing kinase inhibits NFκB activity specifically in neurons of the CNS

Xianrong Mao, Bounleut Phanavanh, Hamdan Hamdan, Andréa Moerman-Herzog, Steven W. Barger

J Neurochem. Author manuscript; available in PMC 2016 Nov 18.

Published in final edited form as: J Neurochem. 2016 Apr; 137(2): 154–163. Published online 2016 Mar 15. doi: 10.1111/jnc.13526

PMCID:: PMC5115916

Abstract Article PDF–1022K

Select item 476643510.

Cell intrinsic role of NF-κB-inducing kinase in regulating T cell-mediated immune and autoimmune responses

Yanchuan Li, Hui Wang, Xiaofei Zhou, Xiaoping Xie, Xiang Chen, Zuliang Jie, Qiang Zou, Hongbo Hu, Lele Zhu, Xuhong Cheng, Hans D Brightbill, Lawren C. Wu, Linfang Wang, Shao-Cong Sun

Sci Rep. 2016; 6: 22115. Published online 2016 Feb 25. doi: 10.1038/srep22115

PMCID:: PMC4766435

Abstract Article PDF–1.7M

Select item 436095811.

NIK Is Involved in Nucleosomal Regulation by Enhancing Histone H3 Phosphorylation by IKKα

Gye Young Park, Xuerong Wang, Ningning Hu, Tetyana V. Pedchenko, Timothy S. Blackwell, John W. Christman

J Biol Chem. Author manuscript; available in PMC 2015 Mar 16.

Published in final edited form as: J Biol Chem. 2006 Jul 7; 281(27): 18684–18690. Published online 2006 May 3. doi: 10.1074/jbc.M600733200

PMCID:: PMC4360958

Abstract Article PDF–1.1M

Select item 399064312.

Uncoupling of Glomerular IgA Deposition and Disease Progression in Alymphoplasia Mice with IgA Nephropathy

Masashi Aizawa, Yusuke Suzuki, Hitoshi Suzuki, Huihua Pang, Masao Kihara, Junichiro Nakata, Kenji Yamaji, Satoshi Horikoshi, Yasuhiko Tomino

PLoS One. 2014; 9(4): e95365. Published online 2014 Apr 17. doi: 10.1371/journal.pone.0095365

PMCID:: PMC3990643

Abstract Article PDF–1.0M

Select item 390424313.

Significant involvement of nuclear factor-κB-inducing kinase in proper differentiation of αβ and γδ T cells

Koji Eshima, Motohito Okabe, Satoshi Kajiura, Haruka Noma, Nobukata Shinohara, Kazuya Iwabuchi

Immunology. 2014 Feb; 141(2): 222–232. Published online 2014 Jan 9. doi: 10.1111/imm.12186

PMCID:: PMC3904243

Abstract Article PDF–748K

Select item 381544614.

A cell-intrinsic requirement for NF-κB-inducing kinase (NIK) in CD4 and CD8 T cell memory

Alexander M. Rowe, Susan E. Murray, Hans-Peter Raué, Yoshinobu Koguchi, Mark K. Slifka, David C. Parker

J Immunol. Author manuscript; available in PMC 2014 Oct 1.

Published in final edited form as: J Immunol. 2013 Oct 1; 191(7): 10.4049/jimmunol.1301328. Published online 2013 Sep 4. doi: 10.4049/jimmunol.1301328

PMCID:: PMC3815446

Abstract Article PDF–1.5M

Select item 317108715.

NIK signaling in dendritic cells but not in T cells is required for the development of effector T cells and cell-mediated immune responses

Janin Hofmann, Florian Mair, Melanie Greter, Marc Schmidt-Supprian, Burkhard Becher

J Exp Med. 2011 Aug 29; 208(9): 1917–1929. doi: 10.1084/jem.20110128

PMCID:: PMC3171087

Abstract Article PDF–2.1M

Select item 221344116.

Alymphoplasia (aly)-Type Nuclear Factor κB–Inducing Kinase (Nik) Causes Defects in Secondary Lymphoid Tissue Chemokine Receptor Signaling and Homing of Peritoneal Cells to the Gut-Associated Lymphatic Tissue System

Sidonia Fagarasan, Reiko Shinkura, Tadashi Kamata, Fumiaki Nogaki, Koichi Ikuta, Kei Tashiro, Tasuku Honjo

J Exp Med. 2000 May 1; 191(9): 1477–1486. doi: 10.1084/jem.191.9.1477

PMCID:: PMC2213441

Abstract Article PDF–195K

Select item 219576117.

Lineage-Restricted Function of Nuclear Factor κB–Inducing Kinase (Nik) in Transducing Signals via Cd40

Norman Garceau, Yoko Kosaka, Sally Masters, John Hambor, Reiko Shinkura, Tasuku Honjo, Randolph J. Noelle

J Exp Med. 2000 Jan 17; 191(2): 381–386. doi: 10.1084/jem.191.2.381

PMCID:: PMC2195761

Abstract Article PDF–126K

Select item 178316118.

Impaired protective immunity and T helper 2 responses in alymphoplasia (aly) mutant mice infected with Trichinella spiralis

M Korenaga, Y Akimaru, S M Shamsuzzaman, Y Hashiguchi

Immunology. 2001 Feb; 102(2): 218–224. doi: 10.1046/j.1365-2567.2001.01169.x

PMCID:: PMC1783161

Abstract Article PDF–179K

Select item 141890019.

NF-κB-Inducing Kinase Regulates Selected Gene Expression in the Nod2 Signaling Pathway

Qilin Pan, Vladimir Kravchenko, Alex Katz, Shuang Huang, Masayuki Ii, John C. Mathison, Koichi Kobayashi, Richard A. Flavell, Robert D. Schreiber, David Goeddel, Richard J. Ulevitch

Infect Immun. 2006 Apr; 74(4): 2121–2127. doi: 10.1128/IAI.74.4.2121-2127.2006