PMC Links for Gene (Select 5283) - PMC

Select item 82984221.

An epigenetic GPI anchor defect impairs TLR4 signaling in the B cell transdifferentiation model for primary human monocytes BLaER1

Julia Wegner, Thomas Zillinger, Thais Marina Schlee-Guimaraes, Eva Bartok, Martin Schlee

Sci Rep. 2021; 11: 14983. Published online 2021 Jul 22. doi: 10.1038/s41598-021-94386-z

Correction in:: Sci Rep. 2021; 11: 17661.

PMCID:: PMC8298422

Abstract Article PDF–3.9M

Select item 78395082.

PIGH deficiency can be associated with severe neurodevelopmental and skeletal manifestations

Camille Tremblay‐Laganière, Rauan Kaiyrzhanov, Reza Maroofian, Thi Tuyet Mai Nguyen, Kamran Salayev, Ilana T. Chilton, Wendy K. Chung, Jill A. Madden, Chanika Phornphutkul, Pankaj B. Agrawal, Henry Houlden, Philippe M. Campeau

Clin Genet. 2021 Feb; 99(2): 313–317. Published online 2020 Nov 27. doi: 10.1111/cge.13877

PMCID:: PMC7839508

Abstract Article PDF–958K

Select item 65874643.

Loss of the GPI‐anchor in B‐lymphoblastic leukemia by epigenetic downregulation of PIGH expression

Floris C. Loeff, Kevin Rijs, Esther H. M. van Egmond, Willem H. Zoutman, Xiaohang Qiao, Wilhelmina G. M. Kroes, Sabrina A. J. Veld, Marieke Griffioen, Maarten H. Vermeer, Jacques Neefjes, J. H. Frederik Falkenburg, Constantijn J. M. Halkes, Inge Jedema

Am J Hematol. 2019 Jan; 94(1): 93–102. Published online 2018 Nov 25. doi: 10.1002/ajh.25337

PMCID:: PMC6587464

Abstract Article PDF–2.1M

Select item 60017984.

A homozygous variant disrupting the PIGH start‐codon is associated with developmental delay, epilepsy, and microcephaly

Alistair T. Pagnamenta, Yoshiko Murakami, Consuelo Anzilotti, Hannah Titheradge, Adam J. Oates, Jenny Morton, The DDD Study, Taroh Kinoshita, Usha Kini, Jenny C. Taylor

Hum Mutat. 2018 Jun; 39(6): 822–826. Published online 2018 Mar 30. doi: 10.1002/humu.23420

PMCID:: PMC6001798

Abstract Article PDF–524K

Select item 11704375.

The first step of glycosylphosphatidylinositol biosynthesis is mediated by a complex of PIG-A, PIG-H, PIG-C and GPI1.

R Watanabe, N Inoue, B Westfall, C H Taron, P Orlean, J Takeda, T Kinoshita

EMBO J. 1998 Feb 16; 17(4): 877–885. doi: 10.1093/emboj/17.4.877

PMCID:: PMC1170437

Summary PDF–660K

Select item 3020406.

Initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-P and is regulated by DPM2

Reika Watanabe, Yoshiko Murakami, Mina D. Marmor, Norimitsu Inoue, Yusuke Maeda, Jun Hino, Kenji Kangawa, Michael Julius, Taroh Kinoshita

EMBO J. 2000 Aug 15; 19(16): 4402–4411. doi: 10.1093/emboj/19.16.4402

PMCID:: PMC302040

Abstract Article PDF–477K

Select item 12664227.

The Initial Enzyme for Glycosylphosphatidylinositol Biosynthesis Requires PIG-Y, a Seventh Component

Yoshiko Murakami, Uamporn Siripanyaphinyo, Yeongjin Hong, Yuko Tashima, Yusuke Maeda, Taroh Kinoshita

Mol Biol Cell. 2005 Nov; 16(11): 5236–5246. doi: 10.1091/mbc.E05-08-0743

PMCID:: PMC1266422

Abstract Article PDF–710K

Select item 45461228.

Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development

Yu Hasegawa, Deanne Taylor, Dmitry A. Ovchinnikov, Ernst J. Wolvetang, Laurence de Torrenté, Jessica C. Mar

PLoS Genet. 2015 Aug; 11(8): e1005428. Published online 2015 Aug 19. doi: 10.1371/journal.pgen.1005428

PMCID:: PMC4546122

Abstract Article PDF–4.3M

Select item 69277549.

Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC

Hao Zeng, Johnny Castillo-Cabrera, Mika Manser, Bo Lu, Zinger Yang, Vaik Strande, Damien Begue, Raffaella Zamponi, Shumei Qiu, Frederic Sigoillot, Qiong Wang, Alicia Lindeman, John S Reece-Hoyes, Carsten Russ, Debora Bonenfant, Xiaomo Jiang, Youzhen Wang, Feng Cong

eLife. 2019; 8: e50223. Published online 2019 Nov 19. doi: 10.7554/eLife.50223

PMCID:: PMC6927754

Abstract Article PDF–5.1M

Select item 910630310.

Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors

Xu Feng, Mengfan Tang, Merve Dede, Dan Su, Guangsheng Pei, Dadi Jiang, Chao Wang, Zhen Chen, Mi Li, Litong Nie, Yun Xiong, Siting Li, Jeong-Min Park, Huimin Zhang, Min Huang, Klaudia Szymonowicz, Zhongming Zhao, Traver Hart, Junjie Chen

Sci Adv. 2022 May; 8(19): eabm6638. Published online 2022 May 13. doi: 10.1126/sciadv.abm6638

PMCID:: PMC9106303

Abstract Article PDF–918K

Select item 51531611.

Sequence Comparison of Human and Mouse Genes Reveals a Homologous Block Structure in the Promoter Regions

Yutaka Suzuki, Riu Yamashita, Matsuyuki Shirota, Yuta Sakakibara, Joe Chiba, Junko Mizushima-Sugano, Kenta Nakai, Sumio Sugano

Genome Res. 2004 Sep; 14(9): 1711–1718. doi: 10.1101/gr.2435604

PMCID:: PMC515316

Abstract Article PDF–181K

Select item 756688112.

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism

Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat

Nat Metab. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z

PMCID:: PMC7566881

Abstract Article PDF–4.8M

Select item 464794113.

hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes

Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal

Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012

PMCID:: PMC4647941

Abstract Article

Select item 461721114.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 553161115.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 816503016.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011