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Items: 1 to 20 of 41

1.
Partitioning defective 6 homolog alpha (PARD6A) promotes epithelial–mesenchymal transition via integrin β1-ILK-SNAIL1 pathway in ovarian cancer
Ziwen Lu, Sirui Yuan, Lingling Ruan, Zhigang Tu, Hanqing Liu
Cell Death Dis. 2022 Apr; 13(4): 304. Published online 2022 Apr 5. doi: 10.1038/s41419-022-04756-2
PMCID:
PMC8980072
AbstractArticlePDF–5.0M
2.
mPar6α Controls Neuronal Migration
David J. Solecki, Eve-Ellen Govek, Mary E. Hatten
J Neurosci. 2006 Oct 18; 26(42): 10624–10625. doi: 10.1523/JNEUROSCI.4060-06.2006
PMCID:
PMC6674730
AbstractArticlePDF–78K
3.
TGFβ-induced phosphorylation of Par6 promotes migration and invasion in prostate cancer cells
Y Mu, G Zang, U Engström, C Busch, M Landström
Br J Cancer. 2015 Mar 31; 112(7): 1223–1231. Published online 2015 Mar 10. doi: 10.1038/bjc.2015.71
PMCID:
PMC4385960
AbstractArticlePDF–2.2M
4.
The Polarity Protein Par6 Induces Cell Proliferation and Is Overexpressed in Breast Cancer
Marissa E. Nolan, Victoria Aranda, Sangjun Lee, Balasubramanian Lakshmi, Srinjan Basu, D. Craig Allred, Senthil K. Muthuswamy
Cancer Res. Author manuscript; available in PMC 2010 Oct 3.
Published in final edited form as: Cancer Res. 2008 Oct 15; 68(20): 8201–8209. doi: 10.1158/0008-5472.CAN-07-6567
PMCID:
PMC2948755
AbstractArticlePDF–1.8M
5.
Rit Mutants Confirm Role of MEK/ERK Signaling in Neuronal Differentiation and Reveal Novel Par6 Interaction
Jennifer L. Rudolph, Geng-Xian Shi, Eda Erdogan, Alan P. Fields, Douglas A. Andres
Biochim Biophys Acta. Author manuscript; available in PMC 2008 Jan 7.
Published in final edited form as: Biochim Biophys Acta. 2007 Dec; 1773(12): 1793–1800. Published online 2007 Oct 9. doi: 10.1016/j.bbamcr.2007.09.008
PMCID:
PMC2175081
AbstractArticlePDF–750K
6.
Characterization of Mammalian Par 6 as a Dual-Location Protein
Erin G. Cline, W. James Nelson
Mol Cell Biol. 2007 Jun; 27(12): 4431–4443. Published online 2007 Apr 9. doi: 10.1128/MCB.02235-06
PMCID:
PMC1900068
AbstractArticlePDF–2.7M
7.
PAR3–PAR6–atypical PKC polarity complex proteins in neuronal polarization
Sophie M. Hapak, Carla V. Rothlin, Sourav Ghosh
Cell Mol Life Sci. 2018 Aug; 75(15): 2735–2761. Published online 2018 Apr 25. doi: 10.1007/s00018-018-2828-6
PMCID:
PMC11105418
AbstractArticlePDF–2.5M
8.
A Tuba/Cdc42/Par6A complex is required to ensure singularity in apical domain formation during enterocyte polarization
Lucas J. M. Bruurs, Mirjam C. van der Net, Susan Zwakenberg, Fried J. T. Zwartkruis, Johannes L. Bos
PLoS One. 2018; 13(11): e0207159. Published online 2018 Nov 8. doi: 10.1371/journal.pone.0207159
PMCID:
PMC6224091
AbstractArticlePDF–2.3M
9.
Atypical Protein Kinase C Phosphorylates Par6 and Facilitates Transforming Growth Factor β-Induced Epithelial-to-Mesenchymal Transition
Adrian Gunaratne, Boun L. Thai, Gianni M. Di Guglielmo
Mol Cell Biol. 2013 Mar; 33(5): 874–886. doi: 10.1128/MCB.00837-12
PMCID:
PMC3623079
AbstractArticlePDF–2.5M
10.
A Genome-Wide Screen of CREB Occupancy Identifies the RhoA Inhibitors Par6C and Rnd3 as Regulators of BDNF-Induced Synaptogenesis
Adam Lesiak, Carl Pelz, Hideaki Ando, Mingyan Zhu, Monika Davare, Talley J. Lambert, Katelin F. Hansen, Karl Obrietan, Suzanne M. Appleyard, Soren Impey, Gary A. Wayman
PLoS One. 2013; 8(6): e64658. Published online 2013 Jun 6. doi: 10.1371/journal.pone.0064658
PMCID:
PMC3675129
AbstractArticlePDF–11M
11.
Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6
Cristina Hidalgo-Carcedo, Steven Hooper, Shahid I. Chaudhry, Peter Williamson, Kevin Harrington, Birgit Leitinger, Erik Sahai
Nat Cell Biol. Author manuscript; available in PMC 2011 Jul 1.
Published in final edited form as: Nat Cell Biol. 2011 Jan; 13(1): 49–58. Published online 2010 Dec 19. doi: 10.1038/ncb2133
PMCID:
PMC3018349
AbstractArticlePDF–2.7M
12.
Hook2, a microtubule-binding protein, interacts with Par6α and controls centrosome orientation during polarized cell migration
Emilie Pallesi-Pocachard, Elsa Bazellieres, Annelise Viallat-Lieutaud, Marie-Hélène Delgrossi, Magali Barthelemy-Requin, André Le Bivic, Dominique Massey-Harroche
Sci Rep. 2016; 6: 33259. Published online 2016 Sep 14. doi: 10.1038/srep33259
PMCID:
PMC5021942
AbstractArticlePDF–1.6M
13.
Protein Scaffolds Control Localized Protein Kinase Cζ Activity
Irene S. Tobias, Alexandra C. Newton
J Biol Chem. 2016 Jun 24; 291(26): 13809–13822. Published online 2016 May 3. doi: 10.1074/jbc.M116.729483
PMCID:
PMC4919463
AbstractArticlePDF–2.0M
14.
A role for the TGFβ-Par6 polarity pathway in breast cancer progression
Alicia M. Viloria-Petit, Laurent David, Jun Yong Jia, Tuba Erdemir, Anita L. Bane, Dushanthi Pinnaduwage, Luba Roncari, Masahiro Narimatsu, Rohit Bose, Jason Moffat, John W. Wong, Robert S. Kerbel, Frances P. O'Malley, Irene L. Andrulis, Jeffrey L. Wrana
Proc Natl Acad Sci U S A. 2009 Aug 18; 106(33): 14028–14033. Published online 2009 Aug 10. doi: 10.1073/pnas.0906796106
PMCID:
PMC2729014
AbstractArticlePDF–1.8M
15.
CRB3 Binds Directly to Par6 and Regulates the Morphogenesis of the Tight Junctions in Mammalian Epithelial Cells
Céline Lemmers, Didier Michel, Lydie Lane-Guermonprez, Marie-Hélène Delgrossi, Emmanuelle Médina, Jean-Pierre Arsanto, André Le Bivic
Mol Biol Cell. 2004 Mar; 15(3): 1324–1333. doi: 10.1091/mbc.E03-04-0235
PMCID:
PMC363137
AbstractArticlePDF–730K
16.
Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6
Sarah M. Garrard, Christopher T. Capaldo, Lin Gao, Michael K. Rosen, Ian G. Macara, Diana R. Tomchick
EMBO J. 2003 Mar 3; 22(5): 1125–1133. doi: 10.1093/emboj/cdg110
PMCID:
PMC150343
AbstractArticlePDF–383K
17.
Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFa in glioblastoma
Yael Kusne, Eugenio A. Carrera-Silva, Anthony S. Perry, Elisabeth J. Rushing, Edward K. Mandell, Justin D. Dietrich, Andrea E. Errasti, Daniel Gibbs, Michael E. Berens, Joseph C. Loftus, Christopher Hulme, Weiwei Yang, Zhimin Lu, Kenneth Aldape, Nader Sanai, Carla V. Rothlin, Sourav Ghosh
Sci Signal. Author manuscript; available in PMC 2015 Jun 30.
Published in final edited form as: Sci Signal. 2014 Aug 12; 7(338): ra75. Published online 2014 Aug 12. doi: 10.1126/scisignal.2005196
PMCID:
PMC4486020
AbstractArticlePDF–1.2M
18.
Ect2 links the PKC?-Par6a Complex to Rac1 Activation and Cellular Transformation
Verline Justilien, Alan P. Fields
Oncogene. Author manuscript; available in PMC 2010 Apr 15.
Published in final edited form as: Oncogene. 2009 Oct 15; 28(41): 3597–3607. Published online 2009 Jul 20. doi: 10.1038/onc.2009.217
PMCID:
PMC2762483
AbstractArticlePDF–3.6M
19.
The Centrosomal E3 Ubiquitin Ligase FBXO31-SCF Regulates Neuronal Morphogenesis and Migration
Mayur Vadhvani, Nicola Schwedhelm-Domeyer, Chaitali Mukherjee, Judith Stegmüller
PLoS One. 2013; 8(2): e57530. Published online 2013 Feb 28. doi: 10.1371/journal.pone.0057530
PMCID:
PMC3585373
AbstractArticlePDF–2.2M
20.
Par6α Interacts with the Dynactin Subunit p150Glued and Is a Critical Regulator of Centrosomal Protein Recruitment
Andrew Kodani, Vinh Tonthat, Beibei Wu, Christine Sütterlin
Mol Biol Cell. 2010 Oct 1; 21(19): 3376–3385. doi: 10.1091/mbc.E10-05-0430
PMCID:
PMC2947473
AbstractArticlePDF–2.3M

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