PMC Links for Gene (Select 500281) - PMC

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Items: 13

Select item 40362041.

The DDN Catalytic Motif Is Required for Metnase Functions in Non-homologous End Joining (NHEJ) Repair and Replication Restart

Hyun-Suk Kim, Qiujia Chen, Sung-Kyung Kim, Jac A. Nickoloff, Robert Hromas, Millie M. Georgiadis, Suk-Hee Lee

J Biol Chem. 2014 Apr 11; 289(15): 10930–10938. Published online 2014 Feb 25. doi: 10.1074/jbc.M113.533216

PMCID:: PMC4036204

Abstract Article PDF–1.4M

Select item 33885472.

Biochemical characterization of Metnase's endonuclease activity and its role in NHEJ repair

Brian D. Beck, Sung-Sook Lee, Elizabeth Williamson, Robert A. Hromas, Suk-Hee Lee

Biochemistry. Author manuscript; available in PMC 2012 Jul 3.

Published in final edited form as: Biochemistry. 2011 May 24; 50(20): 4360–4370. Published online 2011 Apr 27. doi: 10.1021/bi200333k

PMCID:: PMC3388547

Abstract Article PDF–3.8M

Select item 13123703.

The SET domain protein Metnase mediates foreign DNA integration and links integration to nonhomologous end-joining repair

Suk-Hee Lee, Masahiko Oshige, Stephen T. Durant, Kanwaldeep Kaur Rasila, Elizabeth A. Williamson, Heather Ramsey, Lori Kwan, Jac A. Nickoloff, Robert Hromas

Proc Natl Acad Sci U S A. 2005 Dec 13; 102(50): 18075–18080. Published online 2005 Dec 6. doi: 10.1073/pnas.0503676102

PMCID:: PMC1312370

Abstract Article PDF–492K

Select item 39631794.

Chk1 phosphorylation of Metnase/SETMAR at Ser495 enhances DNA repair but decreases replication fork restart

Robert Hromas, Elizabeth Williamson, Sheema Fnu, Young-Ju Lee, Su-Jung Park, Brian D. Beck, Jin-Sam You, Andrei Laitao, Jac A. Nickoloff, Suk-Hee Lee

Oncogene. Author manuscript; available in PMC 2014 Mar 24.

Published in final edited form as: Oncogene. 2012 Sep 20; 31(38): 4245–4254. Published online 2012 Jan 9. doi: 10.1038/onc.2011.586

Correction in:: volume 33 on page 536

PMCID:: PMC3963179

Abstract Article PDF–3.0M

Select item 26691295.

Metnase Mediates Resistance to Topoisomerase II Inhibitors in Breast Cancer Cells

Justin Wray, Elizabeth A. Williamson, Melanie Royce, Montaser Shaheen, Brian D. Beck, Suk-Hee Lee, Jac A. Nickoloff, Robert Hromas

PLoS One. 2009; 4(4): e5323. Published online 2009 Apr 24. doi: 10.1371/journal.pone.0005323

PMCID:: PMC2669129

Abstract Article PDF–285K

Select item 25668746.

The SET and transposase domain protein Metnase enhances chromosome decatenation: regulation by automethylation

Elizabeth A. Williamson, Kanwaldeep Kaur Rasila, Lori Kwan Corwin, Justin Wray, Brian D. Beck, Virginia Severns, Charlotte Mobarak, Suk-Hee Lee, Jac A. Nickoloff, Robert Hromas

Nucleic Acids Res. 2008 Oct; 36(18): 5822–5831. Published online 2008 Sep 12. doi: 10.1093/nar/gkn560

PMCID:: PMC2566874

Abstract Article PDF–5.6M

Select item 29043217.

The Transposase Domain Protein Metnase/SETMAR Suppresses Chromosomal Translocations

Justin Wray, Elizabeth A. Williamson, Sean Chester, Jacqueline Farrington, Rosa Sterk, David M. Weinstock, Maria Jasin, Suk-Hee Lee, Jac A. Nickoloff, Robert Hromas

Cancer Genet Cytogenet. Author manuscript; available in PMC 2011 Jul 15.

Published in final edited form as: Cancer Genet Cytogenet. 2010 Jul 15; 200(2): 184–190. doi: 10.1016/j.cancergencyto.2010.04.011

PMCID:: PMC2904321

Abstract Article PDF–819K

Select item 29436108.

Metnase promotes restart and repair of stalled and collapsed replication forks

Leyma P. De Haro, Justin Wray, Elizabeth A. Williamson, Stephen T. Durant, Lori Corwin, Amanda C. Gentry, Neil Osheroff, Suk-Hee Lee, Robert Hromas, Jac A. Nickoloff

Nucleic Acids Res. 2010 Sep; 38(17): 5681–5691. Published online 2010 May 10. doi: 10.1093/nar/gkq339

PMCID:: PMC2943610

Abstract Article PDF–5.4M

Select item 24310289.

Human Pso4 Is a Metnase (SETMAR)-binding Partner That Regulates Metnase Function in DNA Repair

Brian D. Beck, Su-Jung Park, Young-Ju Lee, Yaritzabel Roman, Robert A. Hromas, Suk-Hee Lee

J Biol Chem. 2008 Apr 4; 283(14): 9023–9030. doi: 10.1074/jbc.M800150200

PMCID:: PMC2431028

Abstract Article PDF–439K

Select item 302105910.

Methylation of histone H3 lysine 36 enhances DNA repair by nonhomologous end-joining

Sheema Fnu, Elizabeth A. Williamson, Leyma P. De Haro, Mark Brenneman, Justin Wray, Montaser Shaheen, Krishnan Radhakrishnan, Suk-Hee Lee, Jac A. Nickoloff, Robert Hromas

Proc Natl Acad Sci U S A. 2011 Jan 11; 108(2): 540–545. Published online 2010 Dec 27. doi: 10.1073/pnas.1013571108