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Select item 103595951.

NOVA1 prevents overactivation of the unfolded protein response and facilitates chromatin access during human white adipogenesis

Zhigang Yang, Ping Dong, Jiankun Cao, Na Lin, Shize Ma, Rui Cao, Lei Cai, Lei Wang, Changchang Cao, Yuanchao Xue, Jing Pan, Xiu Li, Kang Wang, Qiwei Liu, Chen Li, Fuxing Gong, Xin Fu, Ran Xiao

Nucleic Acids Res. 2023 Jul 21; 51(13): 6981–6998. Published online 2023 May 29. doi: 10.1093/nar/gkad469

PMCID:: PMC10359595

Abstract Article PDF–2.9M

Select item 80065342.

Reintroduction of the archaic variant of NOVA1 in cortical organoids alters neurodevelopment

Cleber A. Trujillo, Edward S. Rice, Nathan K. Schaefer, Isaac A. Chaim, Emily C. Wheeler, Assael A. Madrigal, Justin Buchanan, Sebastian Preissl, Allen Wang, Priscilla D. Negraes, Ryan A. Szeto, Roberto H. Herai, Alik Huseynov, Mariana S. A. Ferraz, Fernando S. Borges, Alexandre H. Kihara, Ashley Byrne, Maximillian Marin, Christopher Vollmers, Angela N. Brooks, Jonathan D. Lautz, Katerina Semendeferi, Beth Shapiro, Gene W. Yeo, Stephen E. P. Smith, Richard E. Green, Alysson R. Muotri

Science. Author manuscript; available in PMC 2021 Mar 29.

Published in final edited form as: Science. 2021 Feb 12; 371(6530): eaax2537. doi: 10.1126/science.aax2537

PMCID:: PMC8006534

Abstract Article PDF–2.5M

Select item 66777443.

NOVA1 induction by inflammation and NOVA1 suppression by epigenetic regulation in head and neck squamous cell carcinoma

Eun Kyung Kim, Yoon Ah Cho, Mi-kyoung Seo, Hyunmi Ryu, Byoung Chul Cho, Yoon Woo Koh, Sun Och Yoon

Sci Rep. 2019; 9: 11231. Published online 2019 Aug 2. doi: 10.1038/s41598-019-47755-8

Correction in:: Sci Rep. 2020; 10: 21299.

PMCID:: PMC6677744

Abstract Article PDF–2.3M

Select item 41923614.

MiR-181b-5p Downregulates NOVA1 to Suppress Proliferation, Migration and Invasion and Promote Apoptosis in Astrocytoma

Feng Zhi, Qiang Wang, Danni Deng, Naiyuan Shao, Rong Wang, Lian Xue, Suinuan Wang, Xiwei Xia, Yilin Yang

PLoS One. 2014; 9(10): e109124. Published online 2014 Oct 9. doi: 10.1371/journal.pone.0109124

Correction in:: PLoS One. 2024; 19(7): e0306667.

PMCID:: PMC4192361

Abstract Article PDF–1.6M

Select item 39465675.

High Expression of Neuro-Oncological Ventral Antigen 1 Correlates with Poor Prognosis in Hepatocellular Carcinoma

Yi-An Zhang, Ji-Min Zhu, Jie Yin, Wen-Qing Tang, Yan-Mei Guo, Xi-Zhong Shen, Tao-Tao Liu

PLoS One. 2014; 9(3): e90955. Published online 2014 Mar 7. doi: 10.1371/journal.pone.0090955

PMCID:: PMC3946567

Abstract Article PDF–3.9M

Select item 106051286.

Interaction of the C9orf72-Amyotrophic Lateral Sclerosis-Related Proline–Arginine Dipeptide Repeat Protein with the RNA-Binding Protein NOVA1 Causes Decreased Expression of UNC13A Due to Enhanced Inclusion of Cryptic Exons, Which Is Reversed by Betulin Treatment

Ru-Huei Fu, Hui-Jye Chen, Syuan-Yu Hong

Cells. 2023 Oct; 12(20): 2476. Published online 2023 Oct 18. doi: 10.3390/cells12202476

PMCID:: PMC10605128

Abstract Article PDF–12M

Select item 73778897.

miR-27-3p inhibition restore fibroblasts viability in diabetic wound by targeting NOVA1

Peng Zhang, Xiaomei Song, Qirong Dong, Long Zhou, Lei Wang

Aging (Albany NY) 2020 Jul 15; 12(13): 12841–12849. Published online 2020 Jun 26. doi: 10.18632/aging.103266

PMCID:: PMC7377889

Abstract Article PDF–977K

Select item 65787958.

The onconeural antigen Nova-1 is a neuron-specific RNA-binding protein, the activity of which is inhibited by paraneoplastic antibodies

RJ Buckanovich, YY Yang, RB Darnell

J Neurosci. 1996 Feb 1; 16(3): 1114–1122. doi: 10.1523/JNEUROSCI.16-03-01114.1996

PMCID:: PMC6578795

Abstract PDF–3.8M

Select item 64015469.

Physical and Functional Interaction between 5-HT₆ Receptor and Nova-1

Soon-Hee Kim, Misun Seo, Hongik Hwang, Dong-Min Moon, Gi Hoon Son, Kyungjin Kim, Hyewhon Rhim

Exp Neurobiol. 2019 Feb; 28(1): 17–29. Published online 2019 Jan 21. doi: 10.5607/en.2019.28.1.17

PMCID:: PMC6401546

Abstract Article PDF–2.8M

Select item 607903210.

NOVA1 regulates hTERT splicing and cell growth in non-small cell lung cancer

Andrew T. Ludlow, Mandy Sze Wong, Jerome D. Robin, Kimberly Batten, Laura Yuan, Tsung-Po Lai, Nicole Dahlson, Lu Zhang, Ilgen Mender, Enzo Tedone, Mohammed E. Sayed, Woodring E. Wright, Jerry W. Shay

Nat Commun. 2018; 9: 3112. Published online 2018 Aug 6. doi: 10.1038/s41467-018-05582-x

PMCID:: PMC6079032

Abstract Article PDF–1.7M

Select item 590812311.

NOVA1 acts as an oncogene in melanoma via regulating FOXO3a expression

Xin Yu, Heyi Zheng, Matthew T.V. Chan, William K.K. Wu

J Cell Mol Med. 2018 May; 22(5): 2622–2630. Published online 2018 Mar 2. doi: 10.1111/jcmm.13527

PMCID:: PMC5908123

Abstract Article PDF–3.1M

Select item 570545512.

17β-estradiol regulates the RNA binding protein Nova1, which then regulates the alternative splicing of estrogen receptor-β in the aging female rat brain

Cody L. Shults, Caitlin B. Dingwall, Chun K. Kim, Elena Pinceti, Yathindar S. Rao, Toni R. Pak

Neurobiol Aging. Author manuscript; available in PMC 2019 Jan 1.

Published in final edited form as: Neurobiol Aging. 2018 Jan; 61: 13–22. Published online 2017 Sep 14. doi: 10.1016/j.neurobiolaging.2017.09.005

PMCID:: PMC5705455

Abstract Article PDF–1.2M

Select item 506289813.

RNA binding protein Nova1 promotes tumor growth in vivo and its potential mechanism as an oncogene may due to its interaction with GABA_A Receptor-γ2

Yi-An Zhang, Hai-Ning Liu, Ji-Min Zhu, Dan-Ying Zhang, Xi-Zhong Shen, Tao-Tao Liu

J Biomed Sci. 2016; 23: 71. Published online 2016 Oct 12. doi: 10.1186/s12929-016-0288-6

PMCID:: PMC5062898

Abstract Article PDF–1.4M

Select item 482304914.

NOVA1 inhibition by miR-146b-5p in the remnant tissue microenvironment defines occult residual disease after gastric cancer removal

Sun Och Yoon, Eun Kyung Kim, Mira Lee, Woon Yong Jung, Hyunjoo Lee, Youngran Kang, You-Jin Jang, Soon Won Hong, Seung Ho Choi, Woo Ick Yang

Oncotarget. 2016 Jan 19; 7(3): 2475–2495. Published online 2015 Dec 9. doi: 10.18632/oncotarget.6542

PMCID:: PMC4823049

Abstract Article PDF–16M

Select item 450238815.

Quantitative proteomic analysis shows differentially expressed HSPB1 in glioblastoma as a discriminating short from long survival factor and NOVA1 as a differentiation factor between low-grade astrocytoma and oligodendroglioma

Marcela Gimenez, Suely Kazue Nagahashi Marie, Sueli Oba-Shinjo, Miyuki Uno, Clarice Izumi, João Bosco Oliveira, Jose Cesar Rosa

BMC Cancer. 2015; 15: 481. Published online 2015 Jun 25. doi: 10.1186/s12885-015-1473-9

PMCID:: PMC4502388

Abstract Article PDF–1.5M

Select item 23217216.

The neuronal RNA binding protein Nova-1 recognizes specific RNA targets in vitro and in vivo.

R J Buckanovich, R B Darnell

Mol Cell Biol. 1997 Jun; 17(6): 3194–3201. doi: 10.1128/mcb.17.6.3194

PMCID:: PMC232172

Summary PDF–665K

Select item 1850317.

The tetranucleotide UCAY directs the specific recognition of RNA by the Nova K-homology 3 domain

Kirk B. Jensen, Kiran Musunuru, Hal A. Lewis, Stephen K. Burley, Robert B. Darnell

Proc Natl Acad Sci U S A. 2000 May 23; 97(11): 5740–5745. Published online 2000 May 16. doi: 10.1073/pnas.090553997

PMCID:: PMC18503

Abstract Article PDF–331K

Select item 800822018.

Roles of the microRNA-338-3p/NOVA1 axis in retinoblastoma

Shoubin Sun, Runze Wang, Sisi Yi, Sijia Li, Lei Wang, Jianwen Wang

Mol Med Rep. 2021 May; 23(5): 394. Published online 2021 Mar 22. doi: 10.3892/mmr.2021.12033

PMCID:: PMC8008220

Abstract Article PDF–6.2M

Select item 781838119.

TDP-43 and NOVA-1 RNA-binding proteins as competitive splicing regulators of the schizophrenia-associated TNIK gene

Valentina Gumina, Claudia Colombrita, Claudia Fallini, Patrizia Bossolasco, Anna Maria Maraschi, John E. Landers, Vincenzo Silani, Antonia Ratti

Biochim Biophys Acta Gene Regul Mech. Author manuscript; available in PMC 2021 Jan 21.

Published in final edited form as: Biochim Biophys Acta Gene Regul Mech. 2019 Sep; 1862(9): 194413. Published online 2019 Aug 2. doi: 10.1016/j.bbagrm.2019.194413

PMCID:: PMC7818381

Abstract Article PDF–1.7M

Select item 647481120.

NOVA1 directs PTBP1 to hTERT pre-mRNA and promotes telomerase activity in cancer cells

Mohammed E. Sayed, Laura Yuan, Jerome D. Robin, Enzo Tedone, Kimberly Batten, Nicole Dahlson, Woodring E. Wright, Jerry W. Shay, Andrew T. Ludlow

Oncogene. 2019; 38(16): 2937–2952. Published online 2018 Dec 19. doi: 10.1038/s41388-018-0639-8

PMCID:: PMC6474811

Abstract Article PDF–2.5M

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