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Select item 81017291.

Genetic analysis of the Drosophila ESCRT-III complex protein, VPS24, reveals a novel function in lysosome homeostasis

Jonathan R. Florian, Samuel J. DeMatte, Devon M. Sweeder, Richard W. Ordway, Fumiko Kawasaki

PLoS One. 2021; 16(5): e0251184. Published online 2021 May 6. doi: 10.1371/journal.pone.0251184

PMCID:: PMC8101729

Abstract Article PDF–6.9M

Select item 74294912.

Glutamine deprivation alters the origin and function of cancer cell exosomes

Shih‐Jung Fan, Benjamin Kroeger, Pauline P Marie, Esther M Bridges, John D Mason, Kristie McCormick, Christos E Zois, Helen Sheldon, Nasullah Khalid Alham, Errin Johnson, Matthew Ellis, Maria Irina Stefana, Cláudia C Mendes, Stephen Mark Wainwright, Christopher Cunningham, Freddie C Hamdy, John F Morris, Adrian L Harris, Clive Wilson, Deborah CI Goberdhan

EMBO J. 2020 Aug 17; 39(16): e103009. Published online 2020 Jul 28. doi: 10.15252/embj.2019103009

PMCID:: PMC7429491

Abstract Article PDF–5.9M

Select item 66878473.

Vps28 Is Involved in the Intracellular Trafficking of Awd, the Drosophila Homolog of NME1/2

Elisa Mezzofanti, Marilena Ignesti, Tien Hsu, Giuseppe Gargiulo, Valeria Cavaliere

Front Physiol. 2019; 10: 983. Published online 2019 Aug 2. doi: 10.3389/fphys.2019.00983

PMCID:: PMC6687847

Abstract Article PDF–1.4M

Select item 58180654.

An intracellular activation of Smoothened that is independent of Hedgehog stimulation in Drosophila

Kai Jiang, Yajuan Liu, Jie Zhang, Jianhang Jia

J Cell Sci. 2018 Jan 1; 131(1): jcs211367. doi: 10.1242/jcs.211367

PMCID:: PMC5818065

Abstract Article

Select item 49878335.

Deubiquitinase Usp8 regulates α-synuclein clearance and modifies its toxicity in Lewy body disease

Zoi Alexopoulou, Johannes Lang, Rebecca M. Perrett, Myriam Elschami, Madeleine E. D. Hurry, Hyoung Tae Kim, Dimitra Mazaraki, Aron Szabo, Benedikt M. Kessler, Alfred Lewis Goldberg, Olaf Ansorge, Tudor A. Fulga, George K. Tofaris

Proc Natl Acad Sci U S A. 2016 Aug 9; 113(32): E4688–E4697. Published online 2016 Jul 21. doi: 10.1073/pnas.1523597113

PMCID:: PMC4987833

Abstract Article PDF–1.8M

Select item 69005356.

Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and responses to hypoxia

Yi-Wei Tsai, Hsin-Ho Sung, Jian-Chiuan Li, Chun-Yen Yeh, Pei-Yi Chen, Ying-Ju Cheng, Chun-Hong Chen, Yu-Chen Tsai, Cheng-Ting Chien

Proc Natl Acad Sci U S A. 2019 Dec 3; 116(49): 24651–24661. Published online 2019 Oct 30. doi: 10.1073/pnas.1902537116

PMCID:: PMC6900535

Abstract Article PDF–2.7M

Select item 10872367.

A Mutation in dVps28 Reveals a Link between a Subunit of the Endosomal Sorting Complex Required for Transport-I Complex and the Actin Cytoskeleton in Drosophila

Evgueni A. Sevrioukov, Nabil Moghrabi, Mary Kuhn, Helmut Krämer

Mol Biol Cell. 2005 May; 16(5): 2301–2312. doi: 10.1091/mbc.E04-11-1013

PMCID:: PMC1087236

Abstract Article PDF–934K

Select item 48789928.

ESCRT-0 complex modulates Rbf-mutant cell survival by regulating Rhomboid endosomal trafficking and EGFR signaling

Zhentao Sheng, Lijia Yu, Tianyi Zhang, Xun Pei, Xuan Li, Zhihua Zhang, Wei Du

J Cell Sci. 2016 May 15; 129(10): 2075–2084. doi: 10.1242/jcs.182261

PMCID:: PMC4878992

Abstract Article

Select item 22685869.

ESCRT factors restrict mycobacterial growth

Jennifer A. Philips, Maura C. Porto, Hui Wang, Eric J. Rubin, Norbert Perrimon

Proc Natl Acad Sci U S A. 2008 Feb 26; 105(8): 3070–3075. Published online 2008 Feb 19. doi: 10.1073/pnas.0707206105

PMCID:: PMC2268586

Abstract Article PDF–832K

Select item 199730710.

bicoid RNA localization requires specific binding of an endosomal sorting complex

Uwe Irion, Daniel St Johnston

Nature. Author manuscript; available in PMC 2007 Oct 2.

Published in final edited form as: Nature. 2007 Feb 1; 445(7127): 554–558. doi: 10.1038/nature05503

PMCID:: PMC1997307

Abstract Article PDF–1.8M

Select item 291484311.

Identifying Cellular Pathways Modulated by Drosophila Palmitoyl-protein Thioesterase 1 Function

Stephanie Saja, Haley Buff, Alexis C. Smith, Tiffany S. Williams, Christopher A. Korey

Neurobiol Dis. Author manuscript; available in PMC 2011 Oct 1.

Published in final edited form as: Neurobiol Dis. 2010 Oct; 40(1): 135–145. Published online 2010 Mar 3. doi: 10.1016/j.nbd.2010.02.010

PMCID:: PMC2914843

Abstract Article PDF–2.2M

Select item 271550512.

Genetic screen identifies serpin5 as a regulator of the toll pathway and CHMP2B toxicity associated with frontotemporal dementia

S. Tariq Ahmad, Sean T. Sweeney, Jin-A Lee, Neal T. Sweeney, Fen-Biao Gao

Proc Natl Acad Sci U S A. 2009 Jul 21; 106(29): 12168–12173. Published online 2009 Jul 6. doi: 10.1073/pnas.0903134106

PMCID:: PMC2715505

Abstract Article PDF–1.2M

Select item 1038757613.

Role of Rab5 early endosomes in regulating Drosophila gut antibacterial response

Manish Joshi, Annelise Viallat-Lieutaud, Julien Royet

iScience. 2023 Aug 18; 26(8): 107335. Published online 2023 Jul 10. doi: 10.1016/j.isci.2023.107335

PMCID:: PMC10387576

Abstract Article PDF–6.7M

Select item 467802514.

Oligomerization and endocytosis of Hedgehog is necessary for its efficient exovesicular secretion

Anup Parchure, Neha Vyas, Charles Ferguson, Robert G. Parton, Satyajit Mayor

Mol Biol Cell. 2015 Dec 15; 26(25): 4700–4717. doi: 10.1091/mbc.E15-09-0671

PMCID:: PMC4678025

Abstract Article PDF–5.3M

Select item 433797615.

Drosophila Wingless is loaded on exosome-like vesicles but forms a gradient in an exosome-independent manner

Karen Beckett, Solange Monier, Lucy Palmer, Cyrille Alexandre, Hannah Green, Eric Bonneil, Graca Raposo, Pierre Thibault, Roland Le Borgne, Jean-Paul Vincent

Traffic. Author manuscript; available in PMC 2015 Feb 23.

Published in final edited form as: Traffic. 2013 Jan; 14(1): 82–96. Published online 2012 Oct 31. doi: 10.1111/tra.12016

PMCID:: PMC4337976

Abstract Article PDF–1.8M

Select item 324173016.

Synergy between the ESCRT-III complex and Deltex defines a ligand-independent Notch signal

Kazuya Hori, Anindya Sen, Tom Kirchhausen, Spyros Artavanis-Tsakonas

J Cell Biol. 2011 Dec 12; 195(6): 1005–1015. doi: 10.1083/jcb.201104146

PMCID:: PMC3241730

Abstract Article PDF–2.6M

Select item 564804117.

The regulatory isoform rPGRP-LC resolves immune activation through ESCRT-mediated receptor clearance

Claudine Neyen, Christopher Runchel, Fanny Schüpfer, Pascal Meier, Bruno Lemaitre

Nat Immunol. Author manuscript; available in PMC 2017 Oct 19.

Published in final edited form as: Nat Immunol. 2016 Oct; 17(10): 1150–1158. Published online 2016 Aug 22. doi: 10.1038/ni.3536

PMCID:: PMC5648041

Abstract Article PDF–1.9M

Select item 288213518.

Drosophila acinus encodes a novel regulator of endocytic and autophagic trafficking

Adam S. Haberman, Mohammed Ali Akbar, Sanchali Ray, Helmut Krämer

Development. 2010 Jul 1; 137(13): 2157–2166. doi: 10.1242/dev.044230

PMCID:: PMC2882135

Abstract Article

Select item 238610519.

The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling in Drosophila

Gábor Juhász, Jahda H. Hill, Ying Yan, Miklós Sass, Eric H. Baehrecke, Jonathan M. Backer, Thomas P. Neufeld

J Cell Biol. 2008 May 19; 181(4): 655–666. doi: 10.1083/jcb.200712051

PMCID:: PMC2386105

Abstract Article PDF–3.3M

Select item 998608520.

Accessory ESCRT‐III proteins are conserved and selective regulators of Rab11a‐exosome formation

Pauline P. Marie, Shih‐Jung Fan, John Mason, Adam Wells, Cláudia C. Mendes, S. Mark Wainwright, Sheherezade Scott, Roman Fischer, Adrian L. Harris, Clive Wilson, Deborah C. I. Goberdhan

J Extracell Vesicles. 2023 Mar; 12(3): 12311. Published online 2023 Mar 5. doi: 10.1002/jev2.12311