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Select item 53197291.

A saposin deficiency model in Drosophila: Lysosomal storage, progressive neurodegeneration and sensory physiological decline

Samantha J. Hindle, Sarita Hebbar, Dominik Schwudke, Christopher J.H. Elliott, Sean T. Sweeney

Neurobiol Dis. 2017 Feb; 98: 77–87. doi: 10.1016/j.nbd.2016.11.012

PMCID:: PMC5319729

Abstract Article

Select item 54830032.

Characterization of Drosophila Saposin-related mutants as a model for lysosomal sphingolipid storage diseases

Julia Sellin, Heike Schulze, Marie Paradis, Dominic Gosejacob, Cyrus Papan, Andrej Shevchenko, Olympia Ekaterina Psathaki, Achim Paululat, Melanie Thielisch, Konrad Sandhoff, Michael Hoch

Dis Model Mech. 2017 Jun 1; 10(6): 737–750. doi: 10.1242/dmm.027953

PMCID:: PMC5483003

Abstract Article

Select item 47184573.

TDP‐43 loss of function increases TFEB activity and blocks autophagosome–lysosome fusion

Qin Xia, Hongfeng Wang, Zongbing Hao, Cheng Fu, Qingsong Hu, Feng Gao, Haigang Ren, Dong Chen, Junhai Han, Zheng Ying, Guanghui Wang

EMBO J. 2016 Jan 18; 35(2): 121–142. Published online 2015 Dec 23. doi: 10.15252/embj.201591998

PMCID:: PMC4718457

Abstract Article PDF–8.5M

Select item 99787934.

Sphingolipids in neurodegenerative diseases

Xueyang Pan, Debdeep Dutta, Shenzhao Lu, Hugo J. Bellen

Front Neurosci. 2023; 17: 1137893. Published online 2023 Feb 16. doi: 10.3389/fnins.2023.1137893

PMCID:: PMC9978793

Abstract Article PDF–6.2M

Select item 35195375.

Using Answer Set Programming to Integrate RNA Expression with Signalling Pathway Information to Infer How Mutations Affect Ageing

Irene Papatheodorou, Matthias Ziehm, Daniela Wieser, Nazif Alic, Linda Partridge, Janet M. Thornton

PLoS One. 2012; 7(12): e50881. Published online 2012 Dec 10. doi: 10.1371/journal.pone.0050881

PMCID:: PMC3519537

Abstract Article PDF–648K

Select item 26665036.

Identification of Receptor-Tyrosine-Kinase-Signaling Target Genes Reveals Receptor-Specific Activities and Pathway Branchpoints During Drosophila Development

John R. Leatherbarrow, Marc S. Halfon

Genetics. 2009 Apr; 181(4): 1335–1345. doi: 10.1534/genetics.108.098475

PMCID:: PMC2666503

Abstract Article PDF–1.3M

Select item 24102147.

New components of the Drosophila fusome suggest it plays novel roles in signaling and transport

Daniel V. Lighthouse, Michael Buszczak, Allan C. Spradling

Dev Biol. Author manuscript; available in PMC 2009 Jan 23.

Published in final edited form as: Dev Biol. 2008 May 1; 317(1): 59–71. Published online 2008 Feb 20. doi: 10.1016/j.ydbio.2008.02.009

PMCID:: PMC2410214

Abstract Article PDF–14M

Select item 39315048.

Glial Wingless/Wnt Regulates Glutamate Receptor Clustering and Synaptic Physiology at the Drosophila Neuromuscular Junction

Kimberly S. Kerr, Yuly Fuentes-Medel, Cassandra Brewer, Romina Barria, James Ashley, Katharine C. Abruzzi, Amy Sheehan, Ozge E. Tasdemir-Yilmaz, Marc R. Freeman, Vivian Budnik

J Neurosci. 2014 Feb 19; 34(8): 2910–2920. doi: 10.1523/JNEUROSCI.3714-13.2014

PMCID:: PMC3931504

Abstract Article PDF–5.1M

Select item 80008509.

Exploiting the Potential of Drosophila Models in Lysosomal Storage Disorders: Pathological Mechanisms and Drug Discovery

Laura Rigon, Concetta De Filippis, Barbara Napoli, Rosella Tomanin, Genny Orso

Biomedicines. 2021 Mar; 9(3): 268. Published online 2021 Mar 7. doi: 10.3390/biomedicines9030268

PMCID:: PMC8000850

Abstract Article PDF–2.8M

Select item 720545010.

A single-cell atlas of adult Drosophila ovary identifies transcriptional programs and somatic cell lineage regulating oogenesis

Allison Jevitt, Deeptiman Chatterjee, Gengqiang Xie, Xian-Feng Wang, Taylor Otwell, Yi-Chun Huang, Wu-Min Deng

PLoS Biol. 2020 Apr; 18(4): e3000538. Published online 2020 Apr 27. doi: 10.1371/journal.pbio.3000538

PMCID:: PMC7205450

Abstract Article PDF–6.2M

Select item 370512611.

A botanical containing freeze dried açai pulp promotes healthy aging and reduces oxidative damage in sod1 knockdown flies

Mara Laslo, Xiaoping Sun, Cheng-Te Hsiao, Wells W. Wu, Rong-Fong Shen, Sige Zou

Age (Dordr) 2013 Aug; 35(4): 1117–1132. Published online 2012 May 26. doi: 10.1007/s11357-012-9437-3

PMCID:: PMC3705126

Abstract Article PDF–594K

Select item 798619412.

Temperature, rainfall and wind variables underlie environmental adaptation in natural populations of Drosophila melanogaster

María Bogaerts‐Márquez, Sara Guirao‐Rico, Mathieu Gautier, Josefa González

Mol Ecol. 2021 Feb; 30(4): 938–954. Published online 2021 Jan 26. doi: 10.1111/mec.15783

PMCID:: PMC7986194

Abstract Article PDF–1.0M

Select item 273156413.

The endocytic pathway mediates cell entry of dsRNA to induce RNAi silencing

Maria-Carla Saleh, Ronald P. van Rij, Armin Hekele, Amethyst Gillis, Edan Foley, Patrick H. O’Farrell, Raul Andino

Nat Cell Biol. Author manuscript; available in PMC 2009 Aug 25.

Published in final edited form as: Nat Cell Biol. 2006 Aug; 8(8): 793–802. Published online 2006 Jul 23. doi: 10.1038/ncbl439

PMCID:: PMC2731564

Abstract Article PDF–2.3M

Select item 621244414.

Genome-wide patterns of local adaptation in Western European Drosophila melanogaster natural populations

Lidia Mateo, Gabriel E. Rech, Josefa González

Sci Rep. 2018; 8: 16143. Published online 2018 Nov 1. doi: 10.1038/s41598-018-34267-0

PMCID:: PMC6212444

Abstract Article PDF–1.8M

Select item 689439715.

Steroid signaling establishes a female metabolic state and regulates SREBP to control oocyte lipid accumulation

Matthew H. Sieber, Allan C. Spradling

Curr Biol. Author manuscript; available in PMC 2019 Dec 5.

Published in final edited form as: Curr Biol. 2015 Apr 20; 25(8): 993–1004. Published online 2015 Mar 19. doi: 10.1016/j.cub.2015.02.019

PMCID:: PMC6894397

Abstract Article PDF–2.5M

Select item 368862016.

The Hemolymph Proteome of Fed and Starved Drosophila Larvae

Björn Handke, Ingrid Poernbacher, Sandra Goetze, Christian H. Ahrens, Ulrich Omasits, Florian Marty, Nikiana Simigdala, Imke Meyer, Bernd Wollscheid, Erich Brunner, Ernst Hafen, Christian F. Lehner

PLoS One. 2013; 8(6): e67208. Published online 2013 Jun 20. doi: 10.1371/journal.pone.0067208

PMCID:: PMC3688620

Abstract Article PDF–1.5M

Select item 449991917.

A genetic toolkit for tagging intronic MiMIC containing genes

Sonal Nagarkar-Jaiswal, Steven Z DeLuca, Pei-Tseng Lee, Wen-Wen Lin, Hongling Pan, Zhongyuan Zuo, Jiangxing Lv, Allan C Spradling, Hugo J Bellen

eLife. 2015; 4: e08469. Published online 2015 Jun 23. doi: 10.7554/eLife.08469

PMCID:: PMC4499919

Abstract Article PDF–1.6M

Select item 54900118.

Profiling early infection responses: Pseudomonas aeruginosa eludes host defenses by suppressing antimicrobial peptide gene expression

Yiorgos Apidianakis, Michael N. Mindrinos, Wenzhong Xiao, Gee W. Lau, Regina L. Baldini, Ronald W. Davis, Laurence G. Rahme

Proc Natl Acad Sci U S A. 2005 Feb 15; 102(7): 2573–2578. Published online 2005 Feb 4. doi: 10.1073/pnas.0409588102

PMCID:: PMC549001

Abstract Article PDF–586K

Select item 849627719.

A cross-species approach for the identification of Drosophila male sterility genes

Kimihide Ibaraki, Mihoko Nakatsuka, Takashi Ohsako, Masahide Watanabe, Yu Miyazaki, Machi Shirakami, Timothy L Karr, Rikako Sanuki, Masatoshi Tomaru, Toshiyuki Takano-Shimizu-Kouno

G3 (Bethesda) 2021 Aug; 11(8): jkab183. Published online 2021 May 29. doi: 10.1093/g3journal/jkab183