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Select item 75056621.

Ubiquitin-interacting motifs of ataxin-3 regulate its polyglutamine toxicity through Hsc70-4-dependent aggregation

Sean L Johnson, Bedri Ranxhi, Kozeta Libohova, Wei-Ling Tsou, Sokol V Todi

eLife. 2020; 9: e60742. Published online 2020 Sep 21. doi: 10.7554/eLife.60742

PMCID:: PMC7505662

Abstract Article PDF–6.5M

Select item 26839392.

In Vivo Generation of Neurotoxic Prion Protein: Role for Hsp70 in Accumulation of Misfolded Isoforms

Pedro Fernandez-Funez, Sergio Casas-Tinto, Yan Zhang, Melisa Gómez-Velazquez, Marco A. Morales-Garza, Ana C. Cepeda-Nieto, Joaquín Castilla, Claudio Soto, Diego E. Rincon-Limas

PLoS Genet. 2009 Jun; 5(6): e1000507. Published online 2009 Jun 5. doi: 10.1371/journal.pgen.1000507

PMCID:: PMC2683939

Abstract Article PDF–1.5M

Select item 42352613.

Regulation of dopamine release by CASK-β modulates locomotor initiation in Drosophila melanogaster

Justin B. Slawson, Elena A. Kuklin, Konark Mukherjee, Nicolás Pírez, Nathan C. Donelson, Leslie C. Griffith

Front Behav Neurosci. 2014; 8: 394. Published online 2014 Nov 18. doi: 10.3389/fnbeh.2014.00394

PMCID:: PMC4235261

Abstract Article PDF–2.4M

Select item 91143704.

Heat shock protein Grp78/BiP/HspA5 binds directly to TDP-43 and mitigates toxicity associated with disease pathology

Liberty François-Moutal, David Donald Scott, Andrew J. Ambrose, Christopher J. Zerio, Marina Rodriguez-Sanchez, Kumara Dissanayake, Danielle G. May, Jacob M. Carlson, Edward Barbieri, Aubin Moutal, Kyle J. Roux, James Shorter, Rajesh Khanna, Sami J. Barmada, Leeanne McGurk, May Khanna

Sci Rep. 2022; 12: 8140. Published online 2022 May 17. doi: 10.1038/s41598-022-12191-8

PMCID:: PMC9114370

Abstract Article PDF–2.0M

Select item 5174055.

Drosophila atm/telomere fusion is required for telomeric localization of HP1 and telomere position effect

Sarah R. Oikemus, Nadine McGinnis, Joana Queiroz-Machado, Hanna Tukachinsky, Saeko Takada, Claudio E. Sunkel, Michael H. Brodsky

Genes Dev. 2004 Aug 1; 18(15): 1850–1861. doi: 10.1101/gad.1202504

PMCID:: PMC517405

Abstract Article PDF–327K

Select item 96789166.

Hsc70-4 aggravates PolyQ-mediated neurodegeneration by modulating NF-κB mediated immune response in Drosophila

Saurabh Rai, Madhu G. Tapadia

Front Mol Neurosci. 2022; 15: 857257. Published online 2022 Nov 8. doi: 10.3389/fnmol.2022.857257

PMCID:: PMC9678916

Abstract Article PDF–19M

Select item 56794787.

Post-transcriptional inhibition of Hsc70-4/HSPA8 expression leads to synaptic vesicle cycling defects in multiple models of ALS

Alyssa N Coyne, Ileana Lorenzini, Ching-Chieh Chou, Meaghan Torvund, Robert S Rogers, Alexander Starr, Benjamin L Zaepfel, Jennifer Levy, Jeffrey Johannesmeyer, Jacob C Schwartz, Hiroshi Nishimune, Konrad Zinsmaier, Wilfried Rossoll, Rita Sattler, Daniela C Zarnescu

Cell Rep. Author manuscript; available in PMC 2017 Nov 9.

Published in final edited form as: Cell Rep. 2017 Oct 3; 21(1): 110–125. doi: 10.1016/j.celrep.2017.09.028

PMCID:: PMC5679478

Abstract Article PDF–2.2M

Select item 43107858.

Mitochondrial Chaperone TRAP1 Activates the Mitochondrial UPR and Extends Healthspan in Drosophila

Rehan M. Baqri, Arielle V. Pietron, Rewatee H. Gokhale, Brittany A. Turner, Laurie S. Kaguni, Alexander W. Shingleton, Sam Kunes, Kyle E. Miller

Mech Ageing Dev. Author manuscript; available in PMC 2015 Nov 1.

Published in final edited form as: Mech Ageing Dev. 2014 Nov-Dec; 0: 35–45. Published online 2014 Sep 26. doi: 10.1016/j.mad.2014.09.002

PMCID:: PMC4310785

Abstract Article PDF–2.5M

Select item 39264239.

Sqd interacts with the Drosophila retinoblastoma tumor suppressor Rbf

Joseph Ahlander, Giovanni Bosco

Biochem Biophys Res Commun. Author manuscript; available in PMC 2014 Feb 17.

Published in final edited form as: Biochem Biophys Res Commun. 2009 Jun 5; 383(3): 363–367. Published online 2009 Apr 11. doi: 10.1016/j.bbrc.2009.04.018

PMCID:: PMC3926423

Abstract Article PDF–1.6M

Select item 36068810.

Molecular and developmental characterization of the heat shock cognate 4 gene of Drosophila melanogaster.

L A Perkins, J S Doctor, K Zhang, L Stinson, N Perrimon, E A Craig

Mol Cell Biol. 1990 Jun; 10(6): 3232–3238. doi: 10.1128/mcb.10.6.3232

PMCID:: PMC360688

Summary Page Browse PDF–1.4M

Select item 859010211.

Drosophila p38 MAPK interacts with BAG‐3/starvin to regulate age‐dependent protein homeostasis

Sarah M. Ryan, Michael Almassey, Amelia M. Burch, Gia Ngo, Julia M. Martin, David Myers, Devin Compton, Shira Archie, Megan Cross, Lauren Naeger, Ashley Salzman, Alyssa Virola‐Iarussi, Scott A. Barbee, Nathan T. Mortimer, Subhabrata Sanyal, Alysia D. Vrailas‐Mortimer

Aging Cell. 2021 Nov; 20(11): e13481. Published online 2021 Oct 21. doi: 10.1111/acel.13481

PMCID:: PMC8590102

Abstract Article PDF–2.4M

Select item 767374912.

Circular RNAs from BOULE play conserved roles in protection against stress-induced fertility decline

Liuze Gao, Shuhui Chang, Wenjuan Xia, Xiaolin Wang, Chenwang Zhang, Liping Cheng, Xu Liu, Liang Chen, Qinghua Shi, Juan Huang, Eugene Yujun Xu, Ge Shan

Sci Adv. 2020 Nov; 6(46): eabb7426. Published online 2020 Nov 11. doi: 10.1126/sciadv.abb7426

PMCID:: PMC7673749

Abstract Article PDF–2.1M

Select item 584162313.

Myeloid Leukemia Factor acts in a chaperone complex to regulate transcription factor stability and gene expression

Jamie O. Dyer, Arnob Dutta, Madelaine Gogol, Vikki M. Weake, George Dialynas, Xilan Wu, Christopher Seidel, Ying Zhang, Laurence Florens, Michael P. Washburn, Susan M. Abmayr, Jerry L. Workman

J Mol Biol. Author manuscript; available in PMC 2018 Jun 30.

Published in final edited form as: J Mol Biol. 2017 Jun 30; 429(13): 2093–2107. Published online 2016 Oct 27. doi: 10.1016/j.jmb.2016.10.026