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Select item 76808921.

Loss of Drosophila E3 Ubiquitin Ligase Hyd Promotes Extra Mitosis in Germline Cysts and Massive Cell Death During Oogenesis

Natalia V. Dorogova, Yuliya A. Galimova, Elena Us. Bolobolova, Elina M. Baricheva, Svetlana A. Fedorova

Front Cell Dev Biol. 2020; 8: 600868. Published online 2020 Nov 9. doi: 10.3389/fcell.2020.600868

PMCID:: PMC7680892

Abstract Article PDF–4.6M

Select item 40709842.

Drosophila FoxP Mutants Are Deficient in Operant Self-Learning

Ezequiel Mendoza, Julien Colomb, Jürgen Rybak, Hans-Joachim Pflüger, Troy Zars, Constance Scharff, Björn Brembs

PLoS One. 2014; 9(6): e100648. Published online 2014 Jun 25. doi: 10.1371/journal.pone.0100648

PMCID:: PMC4070984

Abstract Article PDF–1.4M

Select item 80575923.

Ubiquitin-protein ligase Ubr5 cooperates with hedgehog signalling to promote skeletal tissue homeostasis

David Mellis, Katherine A. Staines, Silvia Peluso, Ioanna Ch. Georgiou, Natalie Dora, Malgorzata Kubiak, Rob van’t Hof, Michela Grillo, Colin Farquharson, Elaine Kinsella, Anna Thornburn, Stuart H. Ralston, Donald M. Salter, Natalia A. Riobo-Del Galdo, Robert E. Hill, Mark Ditzel

PLoS Genet. 2021 Apr; 17(4): e1009275. Published online 2021 Apr 5. doi: 10.1371/journal.pgen.1009275

PMCID:: PMC8057592

Abstract Article PDF–5.5M

Select item 45593924.

Regulation of hedgehog Ligand Expression by the N-End Rule Ubiquitin-Protein Ligase Hyperplastic Discs and the Drosophila GSK3β Homologue, Shaggy

Sophie Moncrieff, Matthieu Moncan, Flavia Scialpi, Mark Ditzel

PLoS One. 2015; 10(9): e0136760. Published online 2015 Sep 3. doi: 10.1371/journal.pone.0136760

PMCID:: PMC4559392

Abstract Article PDF–29M

Select item 12043805.

Requirement for Cell-Proliferation Control Genes in Drosophila Oogenesis

J. Szabad, V. A. Jursnich, P. J. Bryant

Genetics. 1991 Mar; 127(3): 525–533. doi: 10.1093/genetics/127.3.525

PMCID:: PMC1204380

Summary PDF–2.7M

Select item 28370466.

Animal HECT ubiquitin ligases: evolution and functional implications

Ignacio Marín

BMC Evol Biol. 2010; 10: 56. Published online 2010 Feb 22. doi: 10.1186/1471-2148-10-56

PMCID:: PMC2837046

Abstract Article PDF–700K

Select item 72053187.

Hyd ubiquitinates the NF-κB co-factor Akirin to operate an effective immune response in Drosophila

Alexandre Cammarata-Mouchtouris, Xuan-Hung Nguyen, Adrian Acker, François Bonnay, Akira Goto, Amir Orian, Marie-Odile Fauvarque, Michael Boutros, Jean-Marc Reichhart, Nicolas Matt

PLoS Pathog. 2020 Apr; 16(4): e1008458. Published online 2020 Apr 27. doi: 10.1371/journal.ppat.1008458

PMCID:: PMC7205318

Abstract Article PDF–2.5M

Select item 43516578.

Hyperplastic Discs Differentially Regulates the Transcriptional Outputs of Hedgehog Signaling

Guolun Wang, Xiaofang Tang, Yujie Chen, Jun Cao, Qinzhu Huang, Xuemei Ling, Wenyan Ren, Songqing Liu, Yihui Wu, Lorraine Ray, Xinhua Lin

Mech Dev. Author manuscript; available in PMC 2015 Aug 1.

Published in final edited form as: Mech Dev. 2014 Aug; 133: 117–125. Published online 2014 May 20. doi: 10.1016/j.mod.2014.05.002

PMCID:: PMC4351657

Abstract Article PDF–685K

Select item 29883289.

Casein Kinase 2 Promotes Hedgehog Signaling by Regulating both Smoothened and Cubitus Interruptus

Hongge Jia, Yajuan Liu, Ruohan Xia, Chao Tong, Tao Yue, Jin Jiang, Jianhang Jia

J Biol Chem. 2010 Nov 26; 285(48): 37218–37226. Published online 2010 Sep 27. doi: 10.1074/jbc.M110.174565

PMCID:: PMC2988328

Abstract Article PDF–3.9M

Select item 328362310.

Loss of the Tumor Suppressor Pten Promotes Proliferation of Drosophila melanogaster Cells In Vitro and Gives Rise to Continuous Cell Lines

Steven E. Justiniano, Anne Mathew, Sayan Mitra, Sathiya N. Manivannan, Amanda Simcox

PLoS One. 2012; 7(2): e31417. Published online 2012 Feb 21. doi: 10.1371/journal.pone.0031417

PMCID:: PMC3283623

Abstract Article PDF–435K

Select item 271366211.

Inactivation of Effector Caspases through Nondegradative Polyubiquitylation

Mark Ditzel, Meike Broemer, Tencho Tenev, Clare Bolduc, Tom V. Lee, Kristoffer T.G. Rigbolt, Richard Elliott, Marketa Zvelebil, Blagoy Blagoev, Andreas Bergmann, Pascal Meier

Mol Cell. Author manuscript; available in PMC 2009 Nov 21.

Published in final edited form as: Mol Cell. 2008 Nov 21; 32(4): 540–553. doi: 10.1016/j.molcel.2008.09.025

PMCID:: PMC2713662

Abstract Article PDF–2.7M

Select item 732914312.

NatB regulates Rb mutant cell death and tumor growth by modulating EGFR/MAPK signaling through the N-end rule pathways

Zhentao Sheng, Wei Du

PLoS Genet. 2020 Jun; 16(6): e1008863. Published online 2020 Jun 19. doi: 10.1371/journal.pgen.1008863

PMCID:: PMC7329143

Abstract Article PDF–6.6M

Select item 993043613.

Identification of potential pathways and biomarkers linked to progression in ALS

Roland G. Huber, Swapnil Pandey, Deepak Chhangani, Diego E. Rincon‐Limas, Nathan P. Staff, Crystal Jing Jing Yeo

Ann Clin Transl Neurol. 2023 Feb; 10(2): 150–165. Published online 2022 Dec 19. doi: 10.1002/acn3.51697

PMCID:: PMC9930436

Abstract Article PDF–2.5M

Select item 438861914.

Intellectual disability-associated dBRWD3 regulates gene expression through inhibition of HIRA/YEM-mediated chromatin deposition of histone H3.3

Wei-Yu Chen, Hsueh-Tzu Shih, Kuei-Yan Liu, Zong-Siou Shih, Li-Kai Chen, Tsung-Han Tsai, Mei-Ju Chen, Hsuan Liu, Bertrand Chin-Ming Tan, Chien-Yu Chen, Hsiu-Hsiang Lee, Benjamin Loppin, Ounissa Aït-Ahmed, June-Tai Wu

EMBO Rep. 2015 Apr; 16(4): 528–538. Published online 2015 Feb 9. doi: 10.15252/embr.201439092

Correction in:: EMBO Rep. 2016 Jul; 17(7): 1082.

PMCID:: PMC4388619

Abstract Article PDF–8.2M

Select item 559224415.

Wnt-Dependent Inactivation of the Groucho/TLE Co-repressor by the HECT E3 Ubiquitin Ligase Hyd/UBR5

Joshua E. Flack, Juliusz Mieszczanek, Nikola Novcic, Mariann Bienz

Mol Cell. 2017 Jul 20; 67(2): 181–193.e5. doi: 10.1016/j.molcel.2017.06.009

PMCID:: PMC5592244

Abstract Article

Select item 590993616.

Self-oligomerization regulates stability of survival motor neuron protein isoforms by sequestering an SCF^Slmb degron

Kelsey M. Gray, Kevin A. Kaifer, David Baillat, Ying Wen, Thomas R. Bonacci, Allison D. Ebert, Amanda C. Raimer, Ashlyn M. Spring, Sara ten Have, Jacqueline J. Glascock, Kushol Gupta, Gregory D. Van Duyne, Michael J. Emanuele, Angus I. Lamond, Eric J. Wagner, Christian L. Lorson, A. Gregory Matera

Mol Biol Cell. 2018 Jan 15; 29(2): 96–110. doi: 10.1091/mbc.E17-11-0627