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Items: 1 to 20 of 501

1.
Dynamic genome wide expression profiling of Drosophila head development reveals a novel role of Hunchback in retinal glia cell development and blood-brain barrier integrity
Montserrat Torres-Oliva, Julia Schneider, Gordon Wiegleb, Felix Kaufholz, Nico Posnien
PLoS Genet. 2018 Jan; 14(1): e1007180. Published online 2018 Jan 23. doi: 10.1371/journal.pgen.1007180
PMCID:
PMC5796731
AbstractArticlePDF–22M
2.
The Hunchback temporal transcription factor establishes, but is not required to maintain, early-born neuronal identity
Keiko Hirono, Minoree Kohwi, Matt Q. Clark, Ellie S. Heckscher, Chris Q. Doe
Neural Dev. 2017; 12: 1. Published online 2017 Jan 31. doi: 10.1186/s13064-017-0078-1
PMCID:
PMC5282720
AbstractArticlePDF–6.4M
3.
Precision of Readout at the hunchback Gene: Analyzing Short Transcription Time Traces in Living Fly Embryos
Jonathan Desponds, Huy Tran, Teresa Ferraro, Tanguy Lucas, Carmina Perez Romero, Aurelien Guillou, Cecile Fradin, Mathieu Coppey, Nathalie Dostatni, Aleksandra M. Walczak
PLoS Comput Biol. 2016 Dec; 12(12): e1005256. Published online 2016 Dec 12. doi: 10.1371/journal.pcbi.1005256
PMCID:
PMC5152799
AbstractArticlePDF–3.0M
4.
MARZ: an algorithm to combinatorially analyze gapped n-mer models of transcription factor binding
Rowan G Zellers, Robert A Drewell, Jacqueline M Dresch
BMC Bioinformatics. 2015; 16: 30. Published online 2015 Jan 31. doi: 10.1186/s12859-014-0446-3
PMCID:
PMC4384306
AbstractArticlePDF–1.2M
5.
In silico evolution of the hunchback gene indicates redundancy in cis-regulatory organization and spatial gene expression
Elizaveta A. Zagrijchuk, Marat A. Sabirov, David M. Holloway, Alexander V. Spirov
J Bioinform Comput Biol. Author manuscript; available in PMC 2015 Apr 1.
Published in final edited form as: J Bioinform Comput Biol. 2014 Apr; 12(2): 1441009. Published online 2014 Mar 25. doi: 10.1142/S0219720014410091
PMCID:
PMC4068237
AbstractArticlePDF–1.5M
6.
A Spatial Point Pattern Analysis in Drosophila Blastoderm Embryos Evaluating the Potential Inheritance of Transcriptional States
Feng He, Jun Ma
PLoS One. 2013; 8(4): e60876. Published online 2013 Apr 9. doi: 10.1371/journal.pone.0060876
PMCID:
PMC3621909
AbstractArticlePDF–1.6M
7.
Using Chemistry and Microfluidics To Understand the Spatial Dynamics of Complex Biological Networks
CHRISTIAN J. KASTRUP, MATTHEW K. RUNYON, ELENA M. LUCCHETTA, JESSICA M. PRICE, RUSTEM F. ISMAGILOV
Acc Chem Res. Author manuscript; available in PMC 2008 Dec 4.
Published in final edited form as: Acc Chem Res. 2008 Apr; 41(4): 549–558. Published online 2008 Jan 25. doi: 10.1021/ar700174g
PMCID:
PMC2593841
AbstractArticlePDF–2.7M
8.
Differential regulation of alternative promoters emerges from unified kinetics of enhancer-promoter interaction
Jingyao Wang, Shihe Zhang, Hongfang Lu, Heng Xu
Nat Commun. 2022; 13: 2714. Published online 2022 May 17. doi: 10.1038/s41467-022-30315-6
PMCID:
PMC9114328
AbstractArticlePDF–7.9M
9.
Live imaging and biophysical modeling support a button-based mechanism of somatic homolog pairing in Drosophila
Myron Barber Child, VI, Jack R Bateman, Amir Jahangiri, Armando Reimer, Nicholas C Lammers, Nica Sabouni, Diego Villamarin, Grace C McKenzie-Smith, Justine E Johnson, Daniel Jost, Hernan G Garcia
eLife. 2021; 10: e64412. Published online 2021 Jun 8. doi: 10.7554/eLife.64412
PMCID:
PMC8294847
AbstractArticlePDF–1.7M
10.
Real-time single-cell characterization of the eukaryotic transcription cycle reveals correlations between RNA initiation, elongation, and cleavage
Jonathan Liu, Donald Hansen, Elizabeth Eck, Yang Joon Kim, Meghan Turner, Simon Alamos, Hernan G. Garcia
PLoS Comput Biol. 2021 May; 17(5): e1008999. Published online 2021 May 18. doi: 10.1371/journal.pcbi.1008999
PMCID:
PMC8162642
AbstractArticlePDF–2.4M
11.
A developmental framework linking neurogenesis and circuit formation in the Drosophila CNS
Brandon Mark, Sen-Lin Lai, Aref Arzan Zarin, Laurina Manning, Heather Q Pollington, Ashok Litwin-Kumar, Albert Cardona, James W Truman, Chris Q Doe
eLife. 2021; 10: e67510. Published online 2021 May 11. doi: 10.7554/eLife.67510
PMCID:
PMC8139831
AbstractArticlePDF–11M
12.
A mechanism for hunchback promoters to readout morphogenetic positional information in less than a minute
Jonathan Desponds, Massimo Vergassola, Aleksandra M Walczak
eLife. 2020; 9: e49758. Published online 2020 Jul 29. doi: 10.7554/eLife.49758
PMCID:
PMC7428309
AbstractArticlePDF–4.2M
13.
Bicoid-Dependent Activation of the Target Gene hunchback Requires a Two-Motif Sequence Code in a Specific Basal Promoter
Jia Ling, Kristaley Yui Umezawa, Theresa Scott, Stephen Small
Mol Cell. Author manuscript; available in PMC 2020 Sep 19.
Published in final edited form as: Mol Cell. 2019 Sep 19; 75(6): 1178–1187.e4. Published online 2019 Aug 8. doi: 10.1016/j.molcel.2019.06.038
PMCID:
PMC6754290
AbstractArticlePDF–1.4M
14.
Neuroblast-specific open chromatin allows the temporal transcription factor, Hunchback, to bind neuroblast-specific loci
Sonia Q Sen, Sachin Chanchani, Tony D Southall, Chris Q Doe
eLife. 2019; 8: e44036. Published online 2019 Jan 29. doi: 10.7554/eLife.44036
PMCID:
PMC6377230
AbstractArticlePDF–4.2M
15.
Transcriptional precision and accuracy in development: from measurements to models and mechanisms
Lital Bentovim, Timothy T. Harden, Angela H. DePace
Development. 2017 Nov 1; 144(21): 3855–3866. doi: 10.1242/dev.146563
PMCID:
PMC5702068
AbstractArticle
16.
Probing the impact of temperature on molecular events in a developmental system
David Cheung, Jun Ma
Sci Rep. 2015; 5: 13124. Published online 2015 Aug 19. doi: 10.1038/srep13124
PMCID:
PMC4541335
AbstractArticlePDF–1.7M
17.
COMBINING PROTEIN AND mRNA QUANTIFICATION TO DECIPHER TRANSCRIPTIONAL REGULATION
Heng Xu, Leonardo A. Sepúlveda, Lauren Figard, Anna Marie Sokac, Ido Golding
Nat Methods. Author manuscript; available in PMC 2016 Feb 1.
Published in final edited form as: Nat Methods. 2015 Aug; 12(8): 739–742. Published online 2015 Jun 22. doi: 10.1038/nmeth.3446
PMCID:
PMC4521975
AbstractArticlePDF–827K
18.
Mid-Embryo Patterning and Precision in Drosophila Segmentation: Krüppel Dual Regulation of hunchback
David M. Holloway, Alexander V. Spirov
PLoS One. 2015; 10(3): e0118450. Published online 2015 Mar 20. doi: 10.1371/journal.pone.0118450
PMCID:
PMC4368514
AbstractArticlePDF–3.5M
19.
The role of Bicoid cooperative binding in the patterning of sharp borders in Drosophila melanogaster
F.J.P. Lopes, A.V. Spirov, P.M. Bisch
Dev Biol. Author manuscript; available in PMC 2013 Oct 15.
Published in final edited form as: Dev Biol. 2012 Oct 15; 370(2): 165–172. Published online 2012 Jul 25. doi: 10.1016/j.ydbio.2012.07.020
PMCID:
PMC3443333
AbstractArticlePDF–1.0M
20.
Fine mapping of chromatin structure in Drosophila melanogaster embryos using micrococcal nuclease
Li M Li, David N Arnosti
Fly (Austin) 2010 Jul-Sep; 4(3): 213–215. doi: 10.4161/fly.4.3.12200
PMCID:
PMC3322504
AbstractArticlePDF–442K

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