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Select item 105387021.

The endocytic receptor protein LRP-1 modulate P-glycoprotein mediated drug resistance in MCF-7 cells

Aubery Henry, Marine Mauperin, Jerome Devy, Stephane Dedieu, Lise Chazee, Cathy Hachet, Christine Terryn, Laurent Duca, Laurent Martiny, Emmanuelle Devarenne-Charpentier, Hassan El Btaouri

PLoS One. 2023; 18(9): e0285834. Published online 2023 Sep 28. doi: 10.1371/journal.pone.0285834

PMCID:: PMC10538702

Abstract Article PDF–2.1M

Select item 102485562.

Exome-wide analysis reveals role of LRP1 and additional novel loci in cognition

Shreya Chakraborty, Bratati Kahali

HGG Adv. 2023 Jul 13; 4(3): 100208. Published online 2023 May 20. doi: 10.1016/j.xhgg.2023.100208

PMCID:: PMC10248556

Abstract Article PDF–3.8M

Select item 101138943.

Serum Exosomes From Epithelial Ovarian Cancer Patients Contain LRP1, Which Promotes the Migration of Epithelial Ovarian Cancer Cell

Wei Zhou, Jiachen Ma, Han Zhao, Qing Wang, Xiaoli Guo, Linna Chen, Zhonghui Cao, Jiahao Xu, Bei Zhang, Xueyan Zhou

Mol Cell Proteomics. 2023 Apr; 22(4): 100520. Published online 2023 Feb 25. doi: 10.1016/j.mcpro.2023.100520

PMCID:: PMC10113894

Abstract Article PDF–5.1M

Select item 98681024.

LRP-1 Links Post-Translational Modifications to Efficient Presentation of Celiac Disease-Specific T Cell Antigens

Elise Loppinet, Harrison A. Besser, Agnele Sylvia Sewa, Fu-Chen Yang, Bana Jabri, Chaitan Khosla

Cell Chem Biol. Author manuscript; available in PMC 2024 Jan 19.

Published in final edited form as: Cell Chem Biol. 2023 Jan 19; 30(1): 55–68.e10. Published online 2023 Jan 5. doi: 10.1016/j.chembiol.2022.12.002

PMCID:: PMC9868102

Abstract Article PDF–3.5M

Select item 98043905.

Characterization of interaction between blood coagulation factor VIII and LRP1 suggests dynamic binding by alternating complex contacts

Haarin Chun, James H. Kurasawa, Philip Olivares, Ekaterina S. Marakasova, Svetlana A. Shestopal, Gabriela U. Hassink, Elena Karnaukhova, Mary Migliorini, Juliet O. Obi, Ally K. Smith, Patrick L. Wintrode, Prasannavenkatesh Durai, Keunwan Park, Daniel Deredge, Dudley K. Strickland, Andrey G. Sarafanov

J Thromb Haemost. 2022 Oct; 20(10): 2255–2269. Published online 2022 Aug 4. doi: 10.1111/jth.15817

PMCID:: PMC9804390

Abstract Article PDF–16M

Select item 96295476.

Multitarget Activities of Müller Glial Cells and Low-Density Lipoprotein Receptor-Related Protein 1 in Proliferative Retinopathies

María C. Sanchez, Gustavo A. Chiabrando

ASN Neuro. 2022 Jan-Dec; 14: 17590914221136365. Published online 2022 Oct 31. doi: 10.1177/17590914221136365

PMCID:: PMC9629547

Abstract Article PDF–1.4M

Select item 92834677.

LRP-1 receptor combines EGFR signalling and eHsp90α autocrine to support constitutive breast cancer cell motility in absence of blood supply

Cheng Chang, Xin Tang, Daniel Mosallaei, Mei Chen, David T. Woodley, Axel H. Schönthal, Wei Li

Sci Rep. 2022; 12: 12006. Published online 2022 Jul 14. doi: 10.1038/s41598-022-16161-y

PMCID:: PMC9283467

Abstract Article PDF–2.3M

Select item 85565558.

Apolipoprotein E-Containing Lipoproteins and LRP1 Protect From NMDA-Induced Excitotoxicity Associated With Reducing α2-Macroglobulin in Müller Glia

Hideki Hayashi, Misuzu Mori, Mina Harashima, Tatsuya Hashizume, Miho Furiya, Chihaya Mukaigaito, Emi Takemura, Mariko Yamada, Kanako Mise, Bo Yuan, Norio Takagi

Invest Ophthalmol Vis Sci. 2021 Oct; 62(13): 23. Published online 2021 Oct 26. doi: 10.1167/iovs.62.13.23

PMCID:: PMC8556555

Abstract Article PDF–4.8M

Select item 76873809.

LRP1 is a master regulator of tau uptake and spread

Jennifer N. Rauch, Gabriel Luna, Elmer Guzman, Morgane Audouard, Collin Challis, Youssef E. Sibih, Carolina Leshuk, Israel Hernandez, Susanne Wegmann, Bradley T. Hyman, Viviana Gradinaru, Martin Kampmann, Kenneth S. Kosik

Nature. Author manuscript; available in PMC 2020 Nov 25.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 381–385. Published online 2020 Apr 1. doi: 10.1038/s41586-020-2156-5

PMCID:: PMC7687380

Abstract Article PDF–1.9M

Select item 760944310.

Complement C1q Interacts With LRP1 Clusters II and IV Through a Site Close but Different From the Binding Site of Its C1r and C1s-Associated Proteases

Guillaume Fouët, Evelyne Gout, Catherine Wicker-Planquart, Isabelle Bally, Camilla De Nardis, Stéphane Dedieu, Anne Chouquet, Christine Gaboriaud, Nicole M. Thielens, Jean-Philippe Kleman, Véronique Rossi

Front Immunol. 2020; 11: 583754. Published online 2020 Oct 21. doi: 10.3389/fimmu.2020.583754

PMCID:: PMC7609443

Abstract Article PDF–4.3M

Select item 681252211.

Role of the LDL Receptor-Related Protein 1 in Regulating Protease Activity and Signaling Pathways in the Vasculature

Dianaly T. Au, Allison L. Arai, William E. Fondrie, Selen C. Muratoglu, Dudley K. Strickland

Curr Drug Targets. Author manuscript; available in PMC 2019 Oct 24.

Published in final edited form as: Curr Drug Targets. 2018; 19(11): 1276–1288. doi: 10.2174/1389450119666180511162048

PMCID:: PMC6812522

Abstract Article PDF–902K

Select item 671008912.

Truncating variant burden in high-functioning autism and pleiotropic effects of LRP1 across psychiatric phenotypes

Bàrbara Torrico, Alex D. Shaw, Roberto Mosca, Norma Vivó-Luque, Amaia Hervás, Noèlia Fernàndez-Castillo, Patrick Aloy, Mònica Bayés, Janice M. Fullerton, Bru Cormand, Claudio Toma

J Psychiatry Neurosci. 2019 Sep; 44(5): 350–359. Published online 2019 May 16. doi: 10.1503/jpn.180184

PMCID:: PMC6710089

Abstract Article PDF–717K

Select item 669240813.

Furin-mediated cleavage of LRP1 and increase in ICD of LRP1 after cerebral ischemia and after exposure of cultured neurons to NMDA

Mariko Yamada, Hideki Hayashi, Kaori Suzuki, Shoko Sato, Daisuke Inoue, Yui Iwatani, Meiko Ohata, Bo Yuan, Norio Takagi

Sci Rep. 2019; 9: 11782. Published online 2019 Aug 13. doi: 10.1038/s41598-019-48279-x

PMCID:: PMC6692408

Abstract Article PDF–6.2M

Select item 601332114.

LRP-1 Attenuates House Dust Mite-induced Eosinophilic Airway Inflammation by Suppressing Dendritic Cell-mediated Adaptive Immune Responses

Amarjit Mishra, Xianglan Yao, Ankit Saxena, Elizabeth M. Gordon, Maryann Kaler, Rosemarie A. Cuento, Amisha V. Barochia, Pradeep K. Dagur, J. Philip McCoy, Karen J. Keeran, Kenneth R. Jeffries, Xuan Qu, Zu-Xi Yu, Stewart J. Levine

J Allergy Clin Immunol. Author manuscript; available in PMC 2019 Oct 1.

Published in final edited form as: J Allergy Clin Immunol. 2018 Oct; 142(4): 1066–1079.e6. Published online 2017 Dec 21. doi: 10.1016/j.jaci.2017.10.044

PMCID:: PMC6013321

Abstract Article PDF–1.2M

Select item 577356715.

Soluble LRP1 is an independent biomarker of epicardial fat volume in patients with type 1 diabetes mellitus

David de Gonzalo-Calvo, Cristina Colom, David Vilades, Andrea Rivas-Urbina, Abdel-Hakim Moustafa, Montserrat Pérez-Cuellar, Jose Luis Sánchez-Quesada, Antonio Pérez, Vicenta LLorente-Cortes

Sci Rep. 2018; 8: 1054. Published online 2018 Jan 18. doi: 10.1038/s41598-018-19230-3

Correction in:: Sci Rep. 2019; 9: 16715.

PMCID:: PMC5773567

Abstract Article PDF–1007K

Select item 569369416.

Low density lipoprotein receptor-related protein-1 (LRP1) C4408R mutant promotes amyloid precursor protein (APP) α-cleavage in vitro

Huayan Hou, Ahsan Habib, Dan Zi, Kathy Tian, Jun Tian, Brian Giunta, Darrell Sawmiller, Jun Tan

Neuromolecular Med. Author manuscript; available in PMC 2018 Sep 1.

Published in final edited form as: Neuromolecular Med. 2017 Sep; 19(2-3): 300–308. Published online 2017 Jun 13. doi: 10.1007/s12017-017-8446-x

PMCID:: PMC5693694

Abstract Article PDF–748K

Select item 569113617.

The role of CXCR3/LRP1 cross-talk in the invasion of primary brain tumors

Kevin Boyé, Nadège Pujol, Isabel D Alves, Ya-Ping Chen, Thomas Daubon, Yi-Zong Lee, Stephane Dedieu, Marion Constantin, Lorenzo Bello, Marco Rossi, Rolf Bjerkvig, Shih-Che Sue, Andreas Bikfalvi, Clotilde Billottet

Nat Commun. 2017; 8: 1571. Published online 2017 Nov 17. doi: 10.1038/s41467-017-01686-y

PMCID:: PMC5691136

Abstract Article PDF–7.5M

Select item 566125018.

Extracellular vesicles do not contribute to higher circulating levels of soluble LRP1 in idiopathic dilated cardiomyopathy

Santiago Roura, Carolina Gálvez‐Montón, David de Gonzalo‐Calvo, Ana Gámez Valero, Paloma Gastelurrutia, Elena Revuelta‐López, Cristina Prat‐Vidal, Carolina Soler‐Botija, Aida Llucià‐Valldeperas, Isaac Perea‐Gil, Oriol Iborra‐Egea, Francesc E. Borràs, Josep Lupón, Vicenta Llorente‐Cortés, Antoni Bayes‐Genis

J Cell Mol Med. 2017 Nov; 21(11): 3000–3009. Published online 2017 May 29. doi: 10.1111/jcmm.13211

PMCID:: PMC5661250

Abstract Article PDF–724K

Select item 558876819.

T‐cell regulation through a basic suppressive mechanism targeting low‐density lipoprotein receptor‐related protein 1

Jeneen Panezai, Eva Bergdahl, Karl‐Gösta Sundqvist

Immunology. 2017 Oct; 152(2): 308–327. Published online 2017 Jul 10. doi: 10.1111/imm.12770

PMCID:: PMC5588768

Abstract Article PDF–1.1M

Select item 556996620.

Role of LRP-1 in cancer cell migration in 3-dimensional collagen matrix

Aline Appert-Collin, Amar Bennasroune, Pierre Jeannesson, Christine Terryn, Guy Fuhrmann, Hamid Morjani, Stéphane Dedieu

Cell Adh Migr. 2017; 11(4): 316–326. Published online 2016 Jul 27. doi: 10.1080/19336918.2016.1215788

PMCID:: PMC5569966

Abstract Article PDF–705K

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