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Select item 109578971.

An evolutionary mechanism to assimilate new nutrient sensors into the mTORC1 pathway

Grace Y. Liu, Patrick Jouandin, Raymond E. Bahng, Norbert Perrimon, David M. Sabatini

Nat Commun. 2024; 15: 2517. Published online 2024 Mar 21. doi: 10.1038/s41467-024-46680-3

PMCID:: PMC10957897

Abstract Article PDF–2.0M

Select item 108574342.

Stem cell mTOR signaling directs region-specific cell fate decisions during intestinal nutrient adaptation

Jaakko Mattila, Arto Viitanen, Gaia Fabris, Tetiana Strutynska, Jerome Korzelius, Ville Hietakangas

Sci Adv. 2024 Feb 9; 10(6): eadi2671. Published online 2024 Feb 9. doi: 10.1126/sciadv.adi2671

PMCID:: PMC10857434

Abstract Article PDF–11M

Select item 30245923.

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

Yasemin Sancak, Liron Bar-Peled, Roberto Zoncu, Andrew L. Markhard, Shigeyuki Nada, David M. Sabatini

Cell. Author manuscript; available in PMC 2011 Jan 21.

Published in final edited form as: Cell. 2010 Apr 16; 141(2): 290–303. Published online 2010 Apr 8. doi: 10.1016/j.cell.2010.02.024

PMCID:: PMC3024592

Abstract Article PDF–5.5M

Select item 27438254.

Heterochromatin Protein 1 (HP1a) Positively Regulates Euchromatic Gene Expression through RNA Transcript Association and Interaction with hnRNPs in Drosophila

Lucia Piacentini, Laura Fanti, Rodolfo Negri, Valerio Del Vescovo, Alessandro Fatica, Fabio Altieri, Sergio Pimpinelli

PLoS Genet. 2009 Oct; 5(10): e1000670. Published online 2009 Oct 2. doi: 10.1371/journal.pgen.1000670

PMCID:: PMC2743825

Abstract Article PDF–1.9M

Select item 63196085.

Time-resolved mapping of genetic interactions to model rewiring of signaling pathways

Florian Heigwer, Christian Scheeder, Thilo Miersch, Barbara Schmitt, Claudia Blass, Mischan Vali Pour Jamnani, Michael Boutros

eLife. 2018; 7: e40174. Published online 2018 Dec 28. doi: 10.7554/eLife.40174

PMCID:: PMC6319608

Abstract Article PDF–3.4M

Select item 78851206.

Wolbachia and Virus Alter the Host Transcriptome at the Interface of Nucleotide Metabolism Pathways

Amelia R. I. Lindsey, Tamanash Bhattacharya, Richard W. Hardy, Irene L. G. Newton

mBio. 2021 Jan-Feb; 12(1): e03472-20. Published online 2021 Feb 9. doi: 10.1128/mBio.03472-20

PMCID:: PMC7885120

Abstract Article PDF–3.5M

Select item 34411847.

Protein phosphorylation changes reveal new candidates in the regulation of egg activation and early embryogenesis in D. melanogaster

Amber R. Krauchunas, Vanessa L. Horner, Mariana F. Wolfner

Dev Biol. Author manuscript; available in PMC 2013 Oct 1.

Published in final edited form as: Dev Biol. 2012 Oct 1; 370(1): 125–134. Published online 2012 Jul 31. doi: 10.1016/j.ydbio.2012.07.024

PMCID:: PMC3441184

Abstract Article PDF–2.5M

Select item 33196088.

Genome-Wide Association Analysis of Oxidative Stress Resistance in Drosophila melanogaster

Allison L. Weber, George F. Khan, Michael M. Magwire, Crystal L. Tabor, Trudy F. C. Mackay, Robert R. H. Anholt

PLoS One. 2012; 7(4): e34745. Published online 2012 Apr 4. doi: 10.1371/journal.pone.0034745

PMCID:: PMC3319608

Abstract Article PDF–1009K

Select item 43915559.

Identification of Genes That Promote or Inhibit Olfactory Memory Formation in Drosophila

Erica Walkinshaw, Yunchao Gai, Caitlin Farkas, Daniel Richter, Eric Nicholas, Krystyna Keleman, Ronald L. Davis

Genetics. 2015 Apr; 199(4): 1173–1182. Published online 2015 Feb 2. doi: 10.1534/genetics.114.173575

PMCID:: PMC4391555

Abstract Article PDF–1.1M

Select item 456802510.

Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions

Albert J. Erives

Dev Genes Evol. 2015; 225(5): 259–273. Published online 2015 Jul 15. doi: 10.1007/s00427-015-0508-1

PMCID:: PMC4568025

Abstract Article PDF–2.8M

Select item 866448611.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 696157812.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 285522113.

A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function

G. Gregory Neely, Keiji Kuba, Anthony Cammarato, Kazuya Isobe, Sabine Amann, Liyong Zhang, Mitsushige Murata, Lisa Elmén, Vaijayanti Gupta, Suchir Arora, Rinku Sarangi, Debasis Dan, Susumu Fujisawa, Takako Usami, Cui-ping Xia, Alex C. Keene, Nakissa N. Alayari, Hiroyuki Yamakawa, Ulrich Elling, Christian Berger, Maria Novatchkova, Rubina Koglgruber, Keiichi Fukuda, Hiroshi Nishina, Mitsuaki Isobe, J. Andrew Pospisilik, Yumiko Imai, Arne Pfeufer, Andrew A Hicks, Peter P. Pramstaller, Sai Subramaniam, Akinori Kimura, Karen Ocorr, Rolf Bodmer, Josef M. Penninger

Cell. Author manuscript; available in PMC 2011 Apr 2.

Published in final edited form as: Cell. 2010 Apr 2; 141(1): 142–153. doi: 10.1016/j.cell.2010.02.023

PMCID:: PMC2855221

Abstract Article PDF–5.3M

Select item 304044114.

A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionary-conserved pain gene

G. Gregory Neely, Andreas Hess, Michael Costigan, Alex C. Keene, Spyros Goulas, Michiel Langeslag, Robert S Griffin, Inna Belfer, Feng Dai, Shad Smith, Luda Diatchenko, Vaijayanti Gupta, Cui-ping Xia, Sabina Amann, Silke Kreitz, Cornelia Heindl-Erdmann, Susanne Wolz, Cindy V. Ly, Suchir Arora, Rinku Sarangi, Debasis Dan, Maria Novatchkova, Mark Rosenzweig, Dustin Gibson, Darwin Truong, Daniel Schramek, Tamara Zoranovic, Shane J. F. Cronin, Belinda Angjeli, Kay Brune, Georg Dietzl, William Maixner, Arabella Meixner, Winston Thomas, J. Andrew Pospisilik, Mattias Alenius, Michaela Kress, Sai Subramaniam, Paul A. Garrity, Hugo J. Bellen, Clifford J. Woolf, Josef M. Penninger

Cell. Author manuscript; available in PMC 2011 Nov 12.

Published in final edited form as: Cell. 2010 Nov 12; 143(4): 628–638. doi: 10.1016/j.cell.2010.09.047

PMCID:: PMC3040441

Abstract Article PDF–2.0M

Select item 353067715.

High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression

Philippe Batut, Alexander Dobin, Charles Plessy, Piero Carninci, Thomas R. Gingeras

Genome Res. 2013 Jan; 23(1): 169–180. doi: 10.1101/gr.139618.112

PMCID:: PMC3530677

Abstract Article PDF–1.5M

Select item 570780516.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900217.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 435288718.

The Release 6 reference sequence of the Drosophila melanogaster genome

Roger A. Hoskins, Joseph W. Carlson, Kenneth H. Wan, Soo Park, Ivonne Mendez, Samuel E. Galle, Benjamin W. Booth, Barret D. Pfeiffer, Reed A. George, Robert Svirskas, Martin Krzywinski, Jacqueline Schein, Maria Carmela Accardo, Elisabetta Damia, Giovanni Messina, María Méndez-Lago, Beatriz de Pablos, Olga V. Demakova, Evgeniya N. Andreyeva, Lidiya V. Boldyreva, Marco Marra, A. Bernardo Carvalho, Patrizio Dimitri, Alfredo Villasante, Igor F. Zhimulev, Gerald M. Rubin, Gary H. Karpen, Susan E. Celniker

Genome Res. 2015 Mar; 25(3): 445–458. doi: 10.1101/gr.185579.114

PMCID:: PMC4352887

Abstract Article PDF–1022K

Select item 282505319.

Sequence Finishing and Mapping of Drosophila melanogaster Heterochromatin

Roger A. Hoskins, Joseph W. Carlson, Cameron Kennedy, David Acevedo, Martha Evans-Holm, Erwin Frise, Kenneth H. Wan, Soo Park, Maria Mendez-Lago, Fabrizio Rossi, Alfredo Villasante, Patrizio Dimitri, Gary H. Karpen, Susan E. Celniker

Science. Author manuscript; available in PMC 2010 Feb 19.

Published in final edited form as: Science. 2007 Jun 15; 316(5831): 1625–1628. doi: 10.1126/science.1139816

PMCID:: PMC2825053

Abstract Article PDF–858K

Select item 281928020.

The Release 5.1 Annotation of Drosophila melanogaster Heterochromatin

Christopher D. Smith, ShengQiang Shu, Christopher J. Mungall, Gary H. Karpen

Science. Author manuscript; available in PMC 2010 Feb 10.

Published in final edited form as: Science. 2007 Jun 15; 316(5831): 1586. doi: 10.1126/science.1139815

Correction in:: volume 317 on page 1325

PMCID:: PMC2819280

Abstract Article PDF–1.3M

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