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1.
LIMK2 Is a Novel Prognostic Biomarker and Correlates With Tumor Immune Cell Infiltration in Lung Squamous Cell Carcinoma
Yongcheng Su, Beibei Xu, Qianwen Shen, Ziyu Lei, Wenqing Zhang, Tianhui Hu
Front Immunol. 2022; 13: 788375. Published online 2022 Feb 22. doi: 10.3389/fimmu.2022.788375
PMCID:
PMC8902256
AbstractArticlePDF–14M
2.
LIMK2 Mediates Resistance to Chemotherapeutic Drugs in Neuroblastoma Cells through Regulation of Drug-Induced Cell Cycle Arrest
Cristina Gamell, Alice V. Schofield, Randy Suryadinata, Boris Sarcevic, Ora Bernard
PLoS One. 2013; 8(8): e72850. Published online 2013 Aug 21. doi: 10.1371/journal.pone.0072850
PMCID:
PMC3749167
AbstractArticlePDF–1.8M
3.
Negative Cross talk between LIMK2 and PTEN promotes Castration Resistant Prostate Cancer Pathogenesis in cells and in vivo
Kumar Nikhil, Mohini Kamra, Asif Raza, Kavita Shah
Cancer Lett. Author manuscript; available in PMC 2022 Feb 1.
Published in final edited form as: Cancer Lett. 2021 Feb 1; 498: 1–18. Published online 2020 Sep 12. doi: 10.1016/j.canlet.2020.09.010
PMCID:
PMC8633979
AbstractArticlePDF–3.2M
4.
Suppression of LIM Kinase 1 and LIM Kinase 2 Limits Glioblastoma Invasion
Joseph Chen, Badriprasad Ananthanarayanan, Kelsey S. Springer, Kayla J. Wolf, Sharon M. Sheyman, Vivien D. Tran, Sanjay Kumar
Cancer Res. Author manuscript; available in PMC 2020 Jul 1.
Published in final edited form as: Cancer Res. 2020 Jan 1; 80(1): 69–78. Published online 2019 Oct 22. doi: 10.1158/0008-5472.CAN-19-1237
PMCID:
PMC6942638
AbstractArticlePDF–1.8M
5.
Elevated LIM kinase 1 in non-metastatic prostate cancer reflects its role in facilitating androgen receptor nuclear translocation
Katerina Mardilovich, Mads Gabrielsen, Lynn McGarry, Clare Orange, Rachana Patel, Emma Shanks, Joanne Edwards, Michael F Olson
Mol Cancer Ther. Author manuscript; available in PMC 2015 Jul 1.
Published in final edited form as: Mol Cancer Ther. 2015 Jan; 14(1): 246–258. Published online 2014 Oct 24. doi: 10.1158/1535-7163.MCT-14-0447
PMCID:
PMC4297197
AbstractArticlePDF–1.6M
6.
ROCK1 and LIMK2 Interact in Spread but Not Blebbing Cancer Cells
Kerry F. Shea, Claire M. Wells, Andrew P. Garner, Gareth E. Jones
PLoS One. 2008; 3(10): e3398. Published online 2008 Oct 14. doi: 10.1371/journal.pone.0003398
PMCID:
PMC2561063
AbstractArticlePDF–369K
7.
Par-3 mediates the inhibition of LIM kinase 2 to regulate cofilin phosphorylation and tight junction assembly
Xinyu Chen, Ian G. Macara
J Cell Biol. 2006 Feb 27; 172(5): 671–678. doi: 10.1083/jcb.200510061
PMCID:
PMC2063700
AbstractArticlePDF–5.1M
8.
NUDT21 inhibits bladder cancer progression through ANXA2 and LIMK2 by alternative polyadenylation
Ming Xiong, Liang Chen, Lijie Zhou, Yong Ding, Gallina Kazobinka, Zhaohui Chen, Teng Hou
Theranostics. 2019; 9(24): 7156–7167. Published online 2019 Sep 23. doi: 10.7150/thno.36030
PMCID:
PMC6831288
AbstractArticlePDF–2.9M
9.
LIMK2 acts as an oncogene in bladder cancer and its functional SNP in the microRNA‐135a binding site affects bladder cancer risk
Wei Wang, Chenglin Yang, Haibo Nie, Xiaofu Qiu, Lianbo Zhang, Yuansong Xiao, Wuer Zhou, Qinsong Zeng, Xiaoming Zhang, Yigao Wu, Jun Liu, Min Ying
Int J Cancer. 2019 Mar 15; 144(6): 1345–1355. Published online 2018 Nov 4. doi: 10.1002/ijc.31757
PMCID:
PMC6587996
AbstractArticlePDF–2.4M
10.
Long non-coding RNA TUG1 is involved in cell growth and chemoresistance of small cell lung cancer by regulating LIMK2b via EZH2
Yuchun Niu, Feng Ma, Weimei Huang, Shun Fang, Man Li, Ting Wei, Linlang Guo
Mol Cancer. 2017; 16: 5. Published online 2017 Jan 9. doi: 10.1186/s12943-016-0575-6
Correction in:
Mol Cancer. 2024; 23: 112.
PMCID:
PMC5223434
AbstractArticlePDF–3.5M
11.
LIMK Regulates Tumor-Cell Invasion and Matrix Degradation Through Tyrosine Phosphorylation of MT1-MMP
Emilie Lagoutte, Clémentine Villeneuve, Laurence Lafanechère, Claire M. Wells, Gareth E. Jones, Philippe Chavrier, Carine Rossé
Sci Rep. 2016; 6: 24925. Published online 2016 Apr 27. doi: 10.1038/srep24925
PMCID:
PMC4847008
AbstractArticlePDF–2.1M
12.
p53-mediated transcriptional regulation and activation of the actin cytoskeleton regulatory RhoC to LIMK2 signaling pathway promotes cell survival
Daniel R Croft, Diane Crighton, Michael S Samuel, Filipe C Lourenco, June Munro, Jenifer Wood, Karim Bensaad, Karen H Vousden, Owen J Sansom, Kevin M Ryan, Michael F Olson
Cell Res. 2011 Apr; 21(4): 666–682. Published online 2010 Nov 16. doi: 10.1038/cr.2010.154
PMCID:
PMC3145139
AbstractArticlePDF–2.9M
13.
Cofilin Phosphorylation and Actin Cytoskeletal Dynamics Regulated by Rho- and Cdc42-Activated Lim-Kinase 2
Tomoyuki Sumi, Kunio Matsumoto, Yoshimi Takai, Toshikazu Nakamura
J Cell Biol. 1999 Dec 27; 147(7): 1519–1532. doi: 10.1083/jcb.147.7.1519
PMCID:
PMC2174243
AbstractArticlePDF–914K
14.
LIM-kinase 2 induces formation of stress fibres, focal adhesions and membrane blebs, dependent on its activation by Rho-associated kinase-catalysed phosphorylation at threonine-505.
T Amano, K Tanabe, T Eto, S Narumiya, K Mizuno
Biochem J. 2001 Feb 15; 354(Pt 1): 149–159. doi: 10.1042/0264-6021:3540149
PMCID:
PMC1221639
SummaryPDF–482K
15.
Reduced LIMK2 expression in colorectal cancer reflects its role in limiting stem cell proliferation
Filipe C Lourenço, June Munro, Jennifer Brown, Julia Cordero, Rhoda Stefanatos, Karen Strathdee, Clare Orange, Stephan M Feller, Owen J Sansom, Marcos Vidal, Graeme I Murray, Michael F Olson
Gut. 2014 Mar; 63(3): 480–493. Published online 2013 Apr 12. doi: 10.1136/gutjnl-2012-303883
PMCID:
PMC3932979
AbstractArticlePDF–5.6M
16.
A novel Rho-dependent pathway that drives interaction of fascin-1 with p-Lin-11/Isl-1/Mec-3 kinase (LIMK) 1/2 to promote fascin-1/actin binding and filopodia stability
Asier Jayo, Maddy Parsons, Josephine C Adams
BMC Biol. 2012; 10: 72. Published online 2012 Aug 10. doi: 10.1186/1741-7007-10-72
PMCID:
PMC3488970
AbstractArticlePDF–5.3M
17.
Nf1 RasGAP Inhibition of LIMK2 Mediates a New Cross-Talk between Ras and Rho Pathways
Béatrice Vallée, Michel Doudeau, Fabienne Godin, Aurélie Gombault, Aurélie Tchalikian, Marie-Ludivine de Tauzia, Hélène Bénédetti
PLoS One. 2012; 7(10): e47283. Published online 2012 Oct 17. doi: 10.1371/journal.pone.0047283
PMCID:
PMC3474823
AbstractArticlePDF–2.5M
18.
LIM Kinase 1 Modulates Cortical Actin and CXCR4 Cycling and Is Activated by HIV-1 to Initiate Viral Infection
Paul J. Vorster, Jia Guo, Alyson Yoder, Weifeng Wang, Yanfang Zheng, Xuehua Xu, Dongyang Yu, Mark Spear, Yuntao Wu
J Biol Chem. 2011 Apr 8; 286(14): 12554–12564. Published online 2011 Feb 14. doi: 10.1074/jbc.M110.182238
PMCID:
PMC3069457
AbstractArticlePDF–1.4M
19.
A GENOME WIDE ASSOCIATION STUDY FOR DIABETIC NEPHROPATHY GENES IN AFRICAN AMERICANS
Caitrin W. McDonough, Nicholette D. Palmer, Pamela J. Hicks, Bong H. Roh, S. Sandy An, Jessica N. Cooke, Jessica M. Hester, Maria R. Wing, Meredith A. Bostrom, Megan E. Rudock, Joshua P. Lewis, Matthew E. Talbert, Rebecca A. Blevins, Lingyi Lu, Maggie C.Y. Ng, Michele M. Sale, Jasmin Divers, Carl D. Langefeld, Barry I. Freedman, Donald W. Bowden
Kidney Int. Author manuscript; available in PMC 2012 Mar 1.
Published in final edited form as: Kidney Int. 2011 Mar; 79(5): 563–572. Published online 2010 Dec 8. doi: 10.1038/ki.2010.467
PMCID:
PMC3056271
AbstractArticlePDF–623K
20.
Altered expression of CDC42 signaling pathway components in cortical layer 3 pyramidal cells in schizophrenia
Dibyadeep Datta, Dominique Arion, John P. Corradi, David A. Lewis
Biol Psychiatry. Author manuscript; available in PMC 2016 Dec 1.
Published in final edited form as: Biol Psychiatry. 2015 Dec 1; 78(11): 775–785. Published online 2015 Apr 11. doi: 10.1016/j.biopsych.2015.03.030
PMCID:
PMC4600637
AbstractArticlePDF–1.3M

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