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Items: 19

Select item 44576101.

Tight Chk1 Levels Control Replication Cluster Activation in Xenopus

Marie Platel, Arach Goldar, Jennifer M. Wiggins, Pedro Barbosa, Pierre Libeau, Pierre Priam, Hemalatha Narassimprakash, Xenia Grodzenski, Kathrin Marheineke

PLoS One. 2015; 10(6): e0129090. Published online 2015 Jun 5. doi: 10.1371/journal.pone.0129090

PMCID:: PMC4457610

Article PDF–5.6M

Select item 21417642.

The Xenopus Chk1 Protein Kinase Mediates a Caffeine-sensitive Pathway of Checkpoint Control in Cell-free Extracts

Akiko Kumagai, Zijian Guo, Katayoon H. Emami, Sophie X. Wang, William G. Dunphy

J Cell Biol. 1998 Sep 21; 142(6): 1559–1569. doi: 10.1083/jcb.142.6.1559

PMCID:: PMC2141764

Article PDF–463K

Select item 18477083.

The structural determinants of checkpoint activation

Christina A. MacDougall, Tony S. Byun, Christopher Van, Muh-ching Yee, Karlene A. Cimprich

Genes Dev. 2007 Apr 15; 21(8): 898–903. doi: 10.1101/gad.1522607

PMCID:: PMC1847708

Article PDF–328K

Select item 3792664.

Regulation of Chk1 Kinase by Autoinhibition and ATR-mediated Phosphorylation

Yoshinori Katsuragi, Noriyuki Sagata

Mol Biol Cell. 2004 Apr; 15(4): 1680–1689. doi: 10.1091/mbc.E03-12-0874

PMCID:: PMC379266

Article PDF–477K

Select item 309635.

Positive Regulation of Wee1 by Chk1 and 14-3-3 Proteins

Joon Lee, Akiko Kumagai, William G. Dunphy

Mol Biol Cell. 2001 Mar; 12(3): 551–563. doi: 10.1091/mbc.12.3.551

PMCID:: PMC30963

Article PDF–552K

Select item 149786.

Dissection of the XChk1 Signaling Pathway in Xenopus laevis Embryos

Nicholas C. Kappas, Pamela Savage, Katherine C. Chen, Allan T. Walls, Jill C. Sible

Mol Biol Cell. 2000 Sep; 11(9): 3101–3108. doi: 10.1091/mbc.11.9.3101

PMCID:: PMC14978

Article PDF–391K

Select item 55058607.

Chk1 Inhibition of the Replication Factor Drf1 Guarantees Cell-Cycle Elongation at the Xenopus laevis Mid-blastula Transition

Clara Collart, James C. Smith, Philip Zegerman

Dev Cell. 2017 Jul 10; 42(1): 82–96.e3. doi: 10.1016/j.devcel.2017.06.010

PMCID:: PMC5505860

Article PDF–7.0M

Select item 43217888.

Interaction of Chk1 with Treslin Negatively Regulates the Initiation of Chromosomal DNA Replication

Cai Guo, Akiko Kumagai, Katharina Schlacher, Anna Shevchenko, Andrej Shevchenko, William G. Dunphy

Mol Cell. Author manuscript; available in PMC 2016 Feb 5.

Published in final edited form as: Mol Cell. 2015 Feb 5; 57(3): 492–505. Published online 2014 Dec 31. doi: 10.1016/j.molcel.2014.12.003

PMCID:: PMC4321788

Article PDF–3.4M

Select item 36390469.

The Mre11-Rad50-Nbs1 (MRN) complex has a specific role in the activation of Chk1 in response to stalled replication forks

Joon Lee, William G. Dunphy

Mol Biol Cell. 2013 May 1; 24(9): 1343–1353. doi: 10.1091/mbc.E13-01-0025

PMCID:: PMC3639046

Article PDF–1.6M

Select item 315680710.

Unfertilized Xenopus Eggs Die by Bad-Dependent Apoptosis under the Control of Cdk1 and JNK

David Du Pasquier, Aude Dupré, Catherine Jessus

PLoS One. 2011; 6(8): e23672. Published online 2011 Aug 16. doi: 10.1371/journal.pone.0023672

PMCID:: PMC3156807

Article PDF–1007K

Select item 293798411.

Histone XH2AX Is Required for Xenopus Anterior Neural Development: CRITICAL ROLE OF THREONINE 16 PHOSPHORYLATION

Sung-Young Lee, Andy T. Y. Lau, Chul-Ho Jeong, Jung-Hyun Shim, Hong-Gyum Kim, Jaebong Kim, Ann M. Bode, Zigang Dong

J Biol Chem. 2010 Sep 17; 285(38): 29525–29534. Published online 2010 Jul 16. doi: 10.1074/jbc.M110.127233

PMCID:: PMC2937984

Article PDF–2.7M

Select item 31702712.

Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts

Zijian Guo, Akiko Kumagai, Sophie X. Wang, William G. Dunphy

Genes Dev. 2000 Nov 1; 14(21): 2745–2756. doi: 10.1101/gad.842500

PMCID:: PMC317027

Article PDF–4.6M

Select item 12539913.

Chk1 is activated transiently and targets Cdc25A for degradation at the Xenopus midblastula transition

Ken Shimuta, Nobushige Nakajo, Katsuhiro Uto, Yoshimasa Hayano, Kenji Okazaki, Noriyuki Sagata

EMBO J. 2002 Jul 15; 21(14): 3694–3703. doi: 10.1093/emboj/cdf357

PMCID:: PMC125399

Article PDF–430K

Select item 442602514.

REV1 is important for the ATR-Chk1 DNA damage response pathway in Xenopus egg extracts

Darla DeStephanis, Melissa McLeod, Shan Yan

Biochem Biophys Res Commun. Author manuscript; available in PMC 2016 May 8.

Published in final edited form as: Biochem Biophys Res Commun. 2015 May 8; 460(3): 609–615. Published online 2015 Mar 20. doi: 10.1016/j.bbrc.2015.03.077

PMCID:: PMC4426025

Article PDF–951K

Select item 369681515.

APE2 is required for ATR-Chk1 checkpoint activation in response to oxidative stress

Jeremy Willis, Yogin Patel, Barry L. Lentz, Shan Yan

Proc Natl Acad Sci U S A. 2013 Jun 25; 110(26): 10592–10597. Published online 2013 Jun 10. doi: 10.1073/pnas.1301445110

PMCID:: PMC3696815

Article PDF–753K

Select item 51450316.

Chk1, but not Chk2, inhibits Cdc25 phosphatases by a novel common mechanism

Katsuhiro Uto, Daigo Inoue, Ken Shimuta, Nobushige Nakajo, Noriyuki Sagata

EMBO J. 2004 Aug 18; 23(16): 3386–3396. Published online 2004 Jul 22. doi: 10.1038/sj.emboj.7600328

PMCID:: PMC514503

Article PDF–362K

Select item 373022917.

DNA polymerase κ-dependent DNA synthesis at stalled replication forks is important for CHK1 activation

Rémy Bétous, Marie-Jeanne Pillaire, Laura Pierini, Siem van der Laan, Bénédicte Recolin, Emma Ohl-Séguy, Caixia Guo, Naoko Niimi, Petr Grúz, Takehiko Nohmi, Errol Friedberg, Christophe Cazaux, Domenico Maiorano, Jean-Sébastien Hoffmann

EMBO J. 2013 Jul 31; 32(15): 2172–2185. Published online 2013 Jun 25. doi: 10.1038/emboj.2013.148