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Select item 98795101.

Shreyasi Chatterjee, Megan Sealey, Eva Ruiz, Chrysia M. Pegasiou, Keeley Brookes, Sam Green, Anna Crisford, Michael Duque-Vasquez, Emma Luckett, Rebecca Robertson, Philippa Richardson, Girish Vajramani, Paul Grundy, Diederik Bulters, Christopher Proud, Mariana Vargas-Caballero, Amritpal Mudher

PLoS One. 2023; 18(1): e0262792. Published online 2023 Jan 26. doi: 10.1371/journal.pone.0262792

PMCID:: PMC9879510

Abstract Article PDF–1.4M

Select item 95409972.

Neuronal induction of BNIP3-mediated mitophagy slows systemic aging in Drosophila

Edward T. Schmid, Jung-Hoon Pyo, David W. Walker

Nat Aging. Author manuscript; available in PMC 2022 Dec 1.

Published in final edited form as: Nat Aging. 2022 Jun; 2(6): 494–507. Published online 2022 May 16. doi: 10.1038/s43587-022-00214-y

PMCID:: PMC9540997

Abstract Article PDF–5.8M

Select item 110040193.

Elevated α-synuclein levels inhibit mitophagic flux

Inge Kinnart, Liselot Manders, Thibaut Heyninck, Dorien Imberechts, Roman Praschberger, Nils Schoovaerts, Catherine Verfaillie, Patrik Verstreken, Wim Vandenberghe

NPJ Parkinsons Dis. 2024; 10: 80. Published online 2024 Apr 9. doi: 10.1038/s41531-024-00696-0

PMCID:: PMC11004019

Abstract Article PDF–6.7M

Select item 65345714.

Rapamycin modulates tissue aging and lifespan independently of the gut microbiota in Drosophila

Joseph M. Schinaman, Anil Rana, William W. Ja, Rebecca I. Clark, David W. Walker

Sci Rep. 2019; 9: 7824. Published online 2019 May 24. doi: 10.1038/s41598-019-44106-5

PMCID:: PMC6534571

Abstract Article PDF–1.7M

Select item 53483105.

Rapamycin enhances survival in a Drosophila model of mitochondrial disease

Adrienne Wang, Jacob Mouser, Jason Pitt, Daniel Promislow, Matt Kaeberlein

Oncotarget. 2016 Dec 6; 7(49): 80131–80139. Published online 2016 Oct 11. doi: 10.18632/oncotarget.12560

PMCID:: PMC5348310

Abstract Article PDF–2.5M

Select item 103120636.

Restoration of Sleep and Circadian Behavior by Autophagy Modulation in Huntington's Disease

Ankit Sharma, Kavyashree Narasimha, Ravi Manjithaya, Vasu Sheeba

J Neurosci. 2023 Jun 28; 43(26): 4907–4925. doi: 10.1523/JNEUROSCI.1894-22.2023

PMCID:: PMC10312063

Abstract Article PDF–7.8M

Select item 78445367.

Intracellular Density of Wolbachia Is Mediated by Host Autophagy and the Bacterial Cytoplasmic Incompatibility Gene cifB in a Cell Type-Dependent Manner in Drosophila melanogaster

Mark Deehan, Weiwei Lin, Benjamin Blum, Andrew Emili, Horacio Frydman

mBio. 2021 Jan-Feb; 12(1): e02205-20. Published online 2021 Jan 12. doi: 10.1128/mBio.02205-20

PMCID:: PMC7844536

Abstract Article PDF–5.1M

Select item 58578898.

Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy

Lara Marrone, Ina Poser, Ian Casci, Julia Japtok, Peter Reinhardt, Antje Janosch, Cordula Andree, Hyun O. Lee, Claudia Moebius, Ellen Koerner, Lydia Reinhardt, Maria Elena Cicardi, Karl Hackmann, Barbara Klink, Angelo Poletti, Simon Alberti, Marc Bickle, Andreas Hermann, Udai Bhan Pandey, Anthony A. Hyman, Jared L. Sterneckert

Stem Cell Reports. 2018 Feb 13; 10(2): 375–389. Published online 2018 Jan 18. doi: 10.1016/j.stemcr.2017.12.018

PMCID:: PMC5857889

Abstract Article PDF–3.3M

Select item 57314149.

Death by over-eating: The Gaucher disease associated gene GBA1, identified in a screen for mediators of autophagic cell death, is necessary for developmental cell death in Drosophila midgut

Santosh K. Dasari, Eyal Schejter, Shani Bialik, Aya Shkedy, Vered Levin-Salomon, Smadar Levin-Zaidman, Adi Kimchi

Cell Cycle. 2017; 16(21): 2003–2010. Published online 2017 Oct 9. doi: 10.1080/15384101.2017.1380134

PMCID:: PMC5731414

Abstract Article PDF–868K

Select item 333607810.

Autophagy can promote but is not required for epithelial cell extrusion in the amnioserosa of the Drosophila embryo

Olga Cormier, Nilufar Mohseni, Iryna Voytyuk, Bruce H Reed

Autophagy. 2012 Feb; 8(2): 252–264. Published online 2012 Feb 1. doi: 10.4161/auto.8.2.18618

PMCID:: PMC3336078

Abstract Article PDF–891K

Select item 294622611.

Molecular characterization of Pegarn: a Drosophila homolog of UNC-51 kinase

A. Ahantarig, L. V. Chadwell, I. B. Terrazas, C. T. Garcia, J. J. Nazarian, H. K. Lee, M. J. Lundell, J. A. Cassill

Mol Biol Rep. Author manuscript; available in PMC 2010 Sep 27.

Published in final edited form as: Mol Biol Rep. 2009 Jul; 36(6): 1311–1321. Published online 2008 Jul 18. doi: 10.1007/s11033-008-9314-4

PMCID:: PMC2946226

Abstract Article PDF–6.5M

Select item 262627712.

Abeta42-Induced Neurodegeneration via an Age-Dependent Autophagic-Lysosomal Injury in Drosophila

Daijun Ling, Ho-Juhn Song, Dan Garza, Thomas P. Neufeld, Paul M. Salvaterra

PLoS One. 2009; 4(1): e4201. Published online 2009 Jan 15. doi: 10.1371/journal.pone.0004201

PMCID:: PMC2626277

Abstract Article PDF–2.0M

Select item 1062955913.

Cyclin-G-associated kinase GAK/dAux regulates autophagy initiation via ULK1/Atg1 in glia

Shiping Zhang, Shuanglong Yi, Linfang Wang, Shuhua Li, Honglei Wang, Li Song, Jiayao Ou, Min Zhang, Ruiqi Wang, Mengxiao Wang, Yuchen Zheng, Kai Yang, Tong Liu, Margaret S. Ho

Proc Natl Acad Sci U S A. 2023 Jul 18; 120(29): e2301002120. Published online 2023 Jul 10. doi: 10.1073/pnas.2301002120

PMCID:: PMC10629559

Abstract Article PDF–6.9M

Select item 1015422314.

Long-lasting geroprotection from brief rapamycin treatment in early adulthood by persistently increased intestinal autophagy

Paula Juricic, Yu-Xuan Lu, Thomas Leech, Lisa F. Drews, Jonathan Paulitz, Jiongming Lu, Tobias Nespital, Sina Azami, Jennifer C. Regan, Emilie Funk, Jenny Fröhlich, Sebastian Grönke, Linda Partridge

Nat Aging. 2022; 2(9): 824–836. Published online 2022 Aug 29. doi: 10.1038/s43587-022-00278-w

PMCID:: PMC10154223

Abstract Article PDF–9.2M

Select item 512368915.

Atg1-independent induction of autophagy by the Drosophila Ulk3 homolog, ADUK

Christopher R. Braden, Thomas P. Neufeld

FEBS J. Author manuscript; available in PMC 2017 Nov 1.

Published in final edited form as: FEBS J. 2016 Nov; 283(21): 3889–3897. Published online 2016 Oct 11. doi: 10.1111/febs.13906

PMCID:: PMC5123689

Abstract Article PDF–1.5M

Select item 792367916.

Cell type-specific modulation of healthspan by Forkhead family transcription factors in the nervous system

Ekin Bolukbasi, Nathaniel S. Woodling, Dobril K. Ivanov, Jennifer Adcott, Andrea Foley, Arjunan Rajasingam, Lauren M. Gittings, Benjamin Aleyakpo, Teresa Niccoli, Janet M. Thornton, Linda Partridge

Proc Natl Acad Sci U S A. 2021 Feb 23; 118(8): e2011491118. Published online 2021 Feb 15. doi: 10.1073/pnas.2011491118

PMCID:: PMC7923679

Abstract Article PDF–1.2M

Select item 685053517.

Overexpression of pink1 or parkin in indirect flight muscles promotes mitochondrial proteostasis and extends lifespan in Drosophila melanogaster

Hongbin Si, Peng Ma, Qiying Liang, Youjie Yin, Ping Wang, Qi Zhang, Saifei Wang, Hansong Deng

PLoS One. 2019; 14(11): e0225214. Published online 2019 Nov 12. doi: 10.1371/journal.pone.0225214

PMCID:: PMC6850535

Abstract Article PDF–1.9M

Select item 600804718.

Deficiency of parkin and PINK1 impairs age-dependent mitophagy in Drosophila

Tom Cornelissen, Sven Vilain, Katlijn Vints, Natalia Gounko, Patrik Verstreken, Wim Vandenberghe

eLife. 2018; 7: e35878. Published online 2018 May 29. doi: 10.7554/eLife.35878

PMCID:: PMC6008047

Abstract Article PDF–4.2M

Select item 558764619.

Promoting Drp1-mediated mitochondrial fission in midlife prolongs healthy lifespan of Drosophila melanogaster

Anil Rana, Matheus P. Oliveira, Andy V. Khamoui, Ricardo Aparicio, Michael Rera, Harry B. Rossiter, David W. Walker

Nat Commun. 2017; 8: 448. Published online 2017 Sep 6. doi: 10.1038/s41467-017-00525-4

PMCID:: PMC5587646

Abstract Article PDF–5.2M

Select item 548300320.

Characterization of Drosophila Saposin-related mutants as a model for lysosomal sphingolipid storage diseases

Julia Sellin, Heike Schulze, Marie Paradis, Dominic Gosejacob, Cyrus Papan, Andrej Shevchenko, Olympia Ekaterina Psathaki, Achim Paululat, Melanie Thielisch, Konrad Sandhoff, Michael Hoch

Dis Model Mech. 2017 Jun 1; 10(6): 737–750. doi: 10.1242/dmm.027953

PMCID:: PMC5483003

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