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Select item 94105541.

Human LAMP1 accelerates Lassa virus fusion and potently promotes fusion pore dilation upon forcing viral fusion with non-endosomal membrane

You Zhang, Juan Carlos de la Torre, Gregory B. Melikyan

PLoS Pathog. 2022 Aug; 18(8): e1010625. Published online 2022 Aug 15. doi: 10.1371/journal.ppat.1010625

PMCID:: PMC9410554

Abstract Article PDF–4.1M

Select item 75501882.

Lysosomal protein surface expression discriminates fat- from bone-forming human mesenchymal precursor cells

Jiajia Xu, Yiyun Wang, Ching-Yun Hsu, Stefano Negri, Robert J Tower, Yongxing Gao, Ye Tian, Takashi Sono, Carolyn A Meyers, Winters R Hardy, Leslie Chang, Shuaishuai Hu, Nusrat Kahn, Kristen Broderick, Bruno Péault, Aaron W James

eLife. 2020; 9: e58990. Published online 2020 Oct 12. doi: 10.7554/eLife.58990

PMCID:: PMC7550188

Abstract Article PDF–6.2M

Select item 61704773.

Hydroxypropyl-beta and -gamma cyclodextrins rescue cholesterol accumulation in Niemann–Pick C1 mutant cell via lysosome-associated membrane protein 1

Ashutosh Singhal, Lajos Szente, James E. K. Hildreth, Byeongwoon Song

Cell Death Dis. 2018 Oct; 9(10): 1019. Published online 2018 Oct 3. doi: 10.1038/s41419-018-1056-1

PMCID:: PMC6170477

Abstract Article PDF–1.3M

Select item 57503984.

Lamp1 Increases the Efficiency of Lassa Virus Infection by Promoting Fusion in Less Acidic Endosomal Compartments

Christine E. Hulseberg, Lucie Fénéant, Katarzyna M. Szymańska, Judith M. White

mBio. 2018 Jan-Feb; 9(1): e01818-17. Published online 2018 Jan 2. doi: 10.1128/mBio.01818-17

PMCID:: PMC5750398

Abstract Article PDF–1.5M

Select item 53863655.

Dysfunctional autophagy in RPE, a contributing factor in age-related macular degeneration

Nady Golestaneh, Yi Chu, Yang-Yu Xiao, Gianna L Stoleru, Alexander C Theos

Cell Death Dis. 2017 Jan; 8(1): e2537. Published online 2017 Jan 5. doi: 10.1038/cddis.2016.453

PMCID:: PMC5386365

Abstract Article PDF–5.6M

Select item 53029366.

Lysosome-associated membrane glycoprotein 1 predicts fratricide amongst T cell receptor transgenic CD8⁺ T cells directed against tumor-associated antigens

Andreas Kirschner, Melanie Thiede, Franziska Blaeschke, Günther H.S. Richter, Julia S. Gerke, Michaela C. Baldauf, Thomas G.P. Grünewald, Dirk H. Busch, Stefan Burdach, Uwe Thiel

Oncotarget. 2016 Aug 30; 7(35): 56584–56597. Published online 2016 Jul 18. doi: 10.18632/oncotarget.10647

PMCID:: PMC5302936

Abstract Article PDF–3.6M

Select item 47439237.

Acidic pH-Induced Conformations and LAMP1 Binding of the Lassa Virus Glycoprotein Spike

Sai Li, Zhaoyang Sun, Rhys Pryce, Marie-Laure Parsy, Sarah K. Fehling, Katrin Schlie, C. Alistair Siebert, Wolfgang Garten, Thomas A. Bowden, Thomas Strecker, Juha T. Huiskonen

PLoS Pathog. 2016 Feb; 12(2): e1005418. Published online 2016 Feb 5. doi: 10.1371/journal.ppat.1005418

PMCID:: PMC4743923

Abstract Article PDF–1.7M

Select item 36931948.

Expression of the lysosomal-associated membrane protein-1 (LAMP-1) in astrocytomas

Stine S Jensen, Charlotte Aaberg-Jessen, Karina G Christensen, Bjarne Kristensen

Int J Clin Exp Pathol. 2013; 6(7): 1294–1305. Published online 2013 Jun 15.

PMCID:: PMC3693194

Abstract Article PDF–2.2M

Select item 35261169.

Generation and characterization of a lysosomally targeted, genetically encoded Ca²⁺-sensor

Hannah V. McCue, Joanna D. Wardyn, Robert D. Burgoyne, Lee P. Haynes

Biochem J. 2013 Jan 15; 449(Pt 2): 449–457. Prepublished online 2012 Oct 25. Published online 2012 Dec 14. doi: 10.1042/BJ20120898

PMCID:: PMC3526116

Abstract Article PDF–938K

Select item 28029410.

Molecular cloning of cDNAs encoding lamp A, a human lysosomal membrane glycoprotein with apparent Mr approximately equal to 120,000.

J Viitala, S R Carlsson, P D Siebert, M Fukuda

Proc Natl Acad Sci U S A. 1988 Jun; 85(11): 3743–3747. doi: 10.1073/pnas.85.11.3743

PMCID:: PMC280294

Summary Page Browse PDF–1.2M

Select item 1091687311.

Lysosomal membrane proteins LAMP1 and LIMP2 are segregated in the Golgi apparatus independently of their clathrin adaptor binding motif

Jason Ecard, Yen-Ling Lian, Séverine Divoux, Zelia Gouveia, Emmanuelle Vigne, Franck Perez, Gaelle Boncompain

Mol Biol Cell. 2024 Mar 1; 35(3): ar42. Published online 2024 Feb 5. doi: 10.1091/mbc.E23-06-0251

PMCID:: PMC10916873

Abstract Article PDF–1.9M

Select item 1078783012.

Loss of RND3/RHOE controls entosis through LAMP1 expression in hepatocellular carcinoma

Sara Basbous, Lydia Dif, Camille Dantzer, Sylvaine Di-Tommaso, Jean-William Dupuy, Paulette Bioulac-Sage, Anne-Aurélie Raymond, Chantal Desdouets, Frédéric Saltel, Violaine Moreau

Cell Death Dis. 2024 Jan; 15(1): 46. Published online 2024 Jan 13. doi: 10.1038/s41419-024-06420-3

PMCID:: PMC10787830

Abstract Article PDF–11M

Select item 661794013.

UBL4A inhibits autophagy-mediated proliferation and metastasis of pancreatic ductal adenocarcinoma via targeting LAMP1

Hongze Chen, Le Li, Jisheng Hu, Zhongjie Zhao, Liang Ji, Chundong Cheng, Guangquan Zhang, Tao zhang, Yilong Li, Hua Chen, Shangha Pan, Bei Sun

J Exp Clin Cancer Res. 2019; 38: 297. Published online 2019 Jul 9. doi: 10.1186/s13046-019-1278-9

PMCID:: PMC6617940

Abstract Article PDF–7.3M

Select item 507721514.

HIV-1 Tat Promotes Lysosomal Exocytosis in Astrocytes and Contributes to Astrocyte-mediated Tat Neurotoxicity

Yan Fan, Johnny J. He

J Biol Chem. 2016 Oct 21; 291(43): 22830–22840. Published online 2016 Sep 8. doi: 10.1074/jbc.M116.731836

PMCID:: PMC5077215

Abstract Article PDF–1.4M

Select item 506896615.

Lysosomal membrane glycoproteins bind cholesterol and contribute to lysosomal cholesterol export

Jian Li, Suzanne R Pfeffer

eLife. 2016; 5: e21635. Published online 2016 Sep 24. doi: 10.7554/eLife.21635

PMCID:: PMC5068966

Abstract Article PDF–2.3M

Select item 490206416.

Direct regulation of LAMP1 by tumor-suppressive microRNA-320a in prostate cancer

ATSUSHI OKATO, YUSUKE GOTO, AKIRA KUROZUMI, MAYUKO KATO, SATOKO KOJIMA, RYOSUKE MATSUSHITA, MASAYA YONEMORI, KAZUTAKA MIYAMOTO, TOMOHIKO ICHIKAWA, NAOHIKO SEKI

Int J Oncol. 2016 Jul; 49(1): 111–122. Published online 2016 May 16. doi: 10.3892/ijo.2016.3522

PMCID:: PMC4902064

Abstract Article PDF–844K

Select item 450566317.

Molecular Mechanism for LAMP1 Recognition by Lassa Virus

Hadas Cohen-Dvashi, Nadav Cohen, Hadar Israeli, Ron Diskin

J Virol. 2015 Aug 1; 89(15): 7584–7592. Published online 2015 May 13. doi: 10.1128/JVI.00651-15

PMCID:: PMC4505663

Abstract Article PDF–4.0M

Select item 428730918.

Attenuated Listeria monocytogenes Vectors Overcome Suppressive Plasma Factors During HIV Infection to Stimulate Myeloid Dendritic Cells to Promote Adaptive Immunity and Reactivation of Latent Virus

Elizabeth A. Miller, Meredith R. Spadaccia, Thomas Norton, Morgan Demmler, Ramya Gopal, Meagan O'Brien, Nathaniel Landau, Thomas W. Dubensky, Jr., Peter Lauer, Dirk G. Brockstedt, Nina Bhardwaj

AIDS Res Hum Retroviruses. 2015 Jan 1; 31(1): 127–136. doi: 10.1089/aid.2014.0138

PMCID:: PMC4287309

Abstract Article PDF–432K

Select item 423999319.

Lassa virus entry requires a trigger-induced receptor switch

Lucas T. Jae, Matthijs Raaben, Andrew S. Herbert, Ana I. Kuehne, Ariel S. Wirchnianski, Timothy Soh, Sarah H. Stubbs, Hans Janssen, Markus Damme, Paul Saftig, Sean P. Whelan, John M. Dye, Thijn R. Brummelkamp

Science. Author manuscript; available in PMC 2014 Dec 27.

Published in final edited form as: Science. 2014 Jun 27; 344(6191): 1506–1510. doi: 10.1126/science.1252480

PMCID:: PMC4239993

Abstract Article PDF–835K

Select item 414151720.

Synergistic defects of different molecules in the cytotoxic pathway lead to clinical familial hemophagocytic lymphohistiocytosis

Kejian Zhang, Shanmuganathan Chandrakasan, Heather Chapman, C. Alexander Valencia, Ammar Husami, Diane Kissell, Judith A. Johnson, Alexandra H. Filipovich

Blood. 2014 Aug 21; 124(8): 1331–1334. Prepublished online 2014 Jun 10. doi: 10.1182/blood-2014-05-573105