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Select item 107971831.

Formin tails act as a switch, inhibiting or enhancing processive actin elongation

Kathryn V. Bremer, Carolyn Wu, Aanand A. Patel, Kevin L. He, Alex M. Grunfeld, Guillaume F. Chanfreau, Margot E. Quinlan

J Biol Chem. 2024 Jan; 300(1): 105557. Published online 2023 Dec 12. doi: 10.1016/j.jbc.2023.105557

PMCID:: PMC10797183

Abstract Article PDF–2.7M

Select item 57678592.

Drosophila and human FHOD family formin proteins nucleate actin filaments

Aanand A. Patel, Zeynep A. Oztug Durer, Aaron P. van Loon, Kathryn V. Bremer, Margot E. Quinlan

J Biol Chem. 2018 Jan 12; 293(2): 532–540. Published online 2017 Nov 10. doi: 10.1074/jbc.M117.800888

PMCID:: PMC5767859

Abstract Article PDF–2.1M

Select item 55600593.

(CCUG)_n RNA toxicity in a Drosophila model of myotonic dystrophy type 2 (DM2) activates apoptosis

Vildan Betul Yenigun, Mario Sirito, Alla Amcheslavky, Tomek Czernuszewicz, Jordi Colonques-Bellmunt, Irma García-Alcover, Marzena Wojciechowska, Clare Bolduc, Zhihong Chen, Arturo López Castel, Ralf Krahe, Andreas Bergmann

Dis Model Mech. 2017 Aug 1; 10(8): 993–1003. doi: 10.1242/dmm.026179

PMCID:: PMC5560059

Abstract Article

Select item 108052864.

Peripheral thickening of the sarcomeres and pointed end elongation of the thin filaments are both promoted by SALS and its formin interaction partners

Dávid Farkas, Szilárd Szikora, A. S. Jijumon, Tamás F. Polgár, Roland Patai, Mónika Ágnes Tóth, Beáta Bugyi, Tamás Gajdos, Péter Bíró, Tibor Novák, Miklós Erdélyi, József Mihály

PLoS Genet. 2024 Jan; 20(1): e1011117. Published online 2024 Jan 10. doi: 10.1371/journal.pgen.1011117

PMCID:: PMC10805286

Abstract Article PDF–4.5M

Select item 59642355.

rbFOX1/MBNL1 competition for CCUG RNA repeats binding contributes to myotonic dystrophy type 1/type 2 differences

Chantal Sellier, Estefanía Cerro-Herreros, Markus Blatter, Fernande Freyermuth, Angeline Gaucherot, Frank Ruffenach, Partha Sarkar, Jack Puymirat, Bjarne Udd, John W. Day, Giovanni Meola, Guillaume Bassez, Harutoshi Fujimura, Masanori P. Takahashi, Benedikt Schoser, Denis Furling, Ruben Artero, Frédéric H. T. Allain, Beatriz Llamusi, Nicolas Charlet-Berguerand

Nat Commun. 2018; 9: 2009. Published online 2018 May 22. doi: 10.1038/s41467-018-04370-x

PMCID:: PMC5964235

Abstract Article PDF–3.6M

Select item 50615456.

The Drosophila formin Fhos is a primary mediator of sarcomeric thin-filament array assembly

Arkadi Shwartz, Nagaraju Dhanyasi, Eyal D Schejter, Ben-Zion Shilo

eLife. 2016; 5: e16540. Published online 2016 Oct 12. doi: 10.7554/eLife.16540

PMCID:: PMC5061545

Abstract Article PDF–9.7M

Select item 54781677.

52 Genetic Loci Influencing Myocardial Mass

Pim van der Harst, Jessica van Setten, Niek Verweij, Georg Vogler, Lude Franke, Matthew T. Maurano, Xinchen Wang, Irene Mateo Leach, Mark Eijgelsheim, Nona Sotoodehnia, Caroline Hayward, Rossella Sorice, Osorio Meirelles, Leo-Pekka Lyytikäinen, Ozren Polašek, Toshiko Tanaka, Dan E. Arking, Sheila Ulivi, Stella Trompet, Martina Müller-Nurasyid, Albert V. Smith, Marcus Dörr, Kathleen F. Kerr, Jared W. Magnani, M. Fabiola Del Greco, Weihua Zhang, Ilja M. Nolte, Claudia T. Silva, Sandosh Padmanabhan, Vinicius Tragante, Tõnu Esko, Gonçalo R. Abecasis, Michiel E. Adriaens, Karl Andersen, Phil Barnett, Joshua C. Bis, Rolf Bodmer, Brendan M. Buckley, Harry Campbell, Megan V. Cannon, Aravinda Chakravarti, Lin Y. Chen, Alessandro Delitala, Richard B. Devereux, Pieter A. Doevendans, Anna F. Dominiczak, Luigi Ferrucci, Ian Ford, Christian Gieger, Tamara B. Harris, Eric Haugen, Matthias Heinig, Dena G. Hernandez, Hans L. Hillege, Joel N. Hirschhorn, Albert Hofman, Norbert Hubner, Shih-Jen Hwang, Annamaria Iorio, Mika Kähönen, Manolis Kellis, Ivana Kolcic, Ishminder K. Kooner, Jaspal S. Kooner, Jan A. Kors, Edward G. Lakatta, Kasper Lage, Lenore J. Launer, Daniel Levy, Alicia Lundby, Peter W. Macfarlane, Dalit May, Thomas Meitinger, Andres Metspalu, Stefania Nappo, Silvia Naitza, Shane Neph, Alex S. Nord, Teresa Nutile, Peter M. Okin, Jesper V. Olsen, Ben A. Oostra, Josef M. Penninger, Len A. Pennacchio, Tune H. Pers, Siegfried Perz, Annette Peters, Yigal M. Pinto, Arne Pfeufer, Maria Grazia Pilia, Peter P. Pramstaller, Bram P. Prins, Olli T. Raitakari, Soumya Raychaudhuri, Ken M. Rice, Elizabeth J. Rossin, Jerome I. Rotter, Sebastian Schafer, David Schlessinger, Carsten O. Schmidt, Jobanpreet Sehmi, Herman H.W. Silljé, Gianfranco Sinagra, Moritz F. Sinner, Kamil Slowikowski, Elsayed Z. Soliman, Timothy D. Spector, Wilko Spiering, John A. Stamatoyannopoulos, Ronald P. Stolk, Konstantin Strauch, Sian-Tsung Tan, Kirill V. Tarasov, Bosco Trinh, Andre G. Uitterlinden, Malou van den Boogaard, Cornelia M. van Duijn, Wiek H. van Gilst, Jorma S. Viikari, Peter M. Visscher, Veronique Vitart, Uwe Völker, Melanie Waldenberger, Christian X. Weichenberger, Harm-Jan Westra, Cisca Wijmenga, Bruce H. Wolffenbuttel, Jian Yang, Connie R. Bezzina, Patricia B. Munroe, Harold Snieder, Alan F. Wright, Igor Rudan, Laurie A. Boyer, Folkert W. Asselbergs, Dirk J. van Veldhuisen, Bruno H. Stricker, Bruce M. Psaty, Marina Ciullo, Serena Sanna, Terho Lehtimäki, James F. Wilson, Stefania Bandinelli, Alvaro Alonso, Paolo Gasparini, J. Wouter Jukema, Stefan Kääb, Vilmundur Gudnason, Stephan B. Felix, Susan R. Heckbert, Rudolf A. de Boer, Christopher Newton-Cheh, Andrew A. Hicks, John C. Chambers, Yalda Jamshidi, Axel Visel, Vincent M. Christoffels, Aaron Isaacs, Nilesh J. Samani, Paul I.W. de Bakker

J Am Coll Cardiol. Author manuscript; available in PMC 2017 Jun 20.

Published in final edited form as: J Am Coll Cardiol. 2016 Sep 27; 68(13): 1435–1448. doi: 10.1016/j.jacc.2016.07.729

PMCID:: PMC5478167

Abstract Article PDF–2.0M

Select item 54408228.

Actin stress fiber organization promotes cell stiffening and proliferation of pre-invasive breast cancer cells

Sandra Tavares, André Filipe Vieira, Anna Verena Taubenberger, Margarida Araújo, Nuno Pimpao Martins, Catarina Brás-Pereira, António Polónia, Maik Herbig, Clara Barreto, Oliver Otto, Joana Cardoso, José B. Pereira-Leal, Jochen Guck, Joana Paredes, Florence Janody

Nat Commun. 2017; 8: 15237. Published online 2017 May 16. doi: 10.1038/ncomms15237

PMCID:: PMC5440822

Abstract Article PDF–5.9M

Select item 82019659.

Temporal integration of inductive cues on the way to gastrulation

Sarah McFann, Sayantan Dutta, Jared E. Toettcher, Stanislav Y. Shvartsman

Proc Natl Acad Sci U S A. 2021 Jun 8; 118(23): e2102691118. Published online 2021 Jun 3. doi: 10.1073/pnas.2102691118

PMCID:: PMC8201965

Abstract Article PDF–1.1M

Select item 605499310.

Modeling of Myotonic Dystrophy Cardiac Phenotypes in Drosophila

Mouli Chakraborty, Beatriz Llamusi, Ruben Artero

Front Neurol. 2018; 9: 473. Published online 2018 Jul 16. doi: 10.3389/fneur.2018.00473

PMCID:: PMC6054993

Abstract Article PDF–928K

Select item 546025411.

Expanded CCUG repeat RNA expression in Drosophila heart and muscle trigger Myotonic Dystrophy type 1-like phenotypes and activate autophagocytosis genes

Estefania Cerro-Herreros, Mouli Chakraborty, Manuel Pérez-Alonso, Rubén Artero, Beatriz Llamusí

Sci Rep. 2017; 7: 2843. Published online 2017 Jun 6. doi: 10.1038/s41598-017-02829-3

PMCID:: PMC5460254

Abstract Article PDF–3.0M

Select item 838045612.

Formin 3 directs dendritic architecture via microtubule regulation and is required for somatosensory nociceptive behavior

Ravi Das, Shatabdi Bhattacharjee, Jamin M. Letcher, Jenna M. Harris, Sumit Nanda, Istvan Foldi, Erin N. Lottes, Hansley M. Bobo, Benjamin D. Grantier, József Mihály, Giorgio A. Ascoli, Daniel N. Cox

Development. 2021 Aug 15; 148(16): dev187609. Published online 2021 Aug 12. doi: 10.1242/dev.187609