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Select item 79181131.

Drosophila Homeodomain-Interacting Protein Kinase (Hipk) Phosphorylates the Hippo/Warts Signalling Effector Yorkie

Eva Louise Steinmetz, Denise Nicole Dewald, Uwe Walldorf

Int J Mol Sci. 2021 Feb; 22(4): 1862. Published online 2021 Feb 13. doi: 10.3390/ijms22041862

PMCID:: PMC7918113

Abstract Article PDF–2.6M

Select item 36135762.

A genome-wide RNA interference screen identifies new regulators of androgen receptor function in prostate cancer cells

Keren Imberg-Kazdan, Susan Ha, Alex Greenfield, Christopher S. Poultney, Richard Bonneau, Susan K. Logan, Michael J. Garabedian

Genome Res. 2013 Apr; 23(4): 581–591. doi: 10.1101/gr.144774.112

PMCID:: PMC3613576

Abstract Article PDF–1.1M

Select item 85043733.

Influence of Sox protein SUMOylation on neural development and regeneration

Kun-Che Chang

Neural Regen Res. 2022 Mar; 17(3): 477–481. Published online 2021 Aug 4. doi: 10.4103/1673-5374.320968

PMCID:: PMC8504373

Abstract Article PDF–826K

Select item 69384064.

Hipk is required for JAK/STAT activity during development and tumorigenesis

Gritta Tettweiler, Jessica A. Blaquiere, Nathan B. Wray, Esther M. Verheyen

PLoS One. 2019; 14(12): e0226856. Published online 2019 Dec 31. doi: 10.1371/journal.pone.0226856

PMCID:: PMC6938406

Abstract Article PDF–3.0M

Select item 86735565.

Expression of human HIPKs in Drosophila demonstrates their shared and unique functions in a developmental model

Stephen D Kinsey, Justin P Vinluan, Gerald A Shipman, Esther M Verheyen

G3 (Bethesda) 2021 Dec; 11(12): jkab350. Published online 2021 Oct 4. doi: 10.1093/g3journal/jkab350

PMCID:: PMC8673556

Abstract Article PDF–1.5M

Select item 69949806.

The nutrient sensor OGT regulates Hipk stability and tumorigenic-like activities in Drosophila

Kenneth Kin Lam Wong, Ta-Wei Liu, Jessica M. Parker, Donald A. R. Sinclair, Yi-Yun Chen, Kay-Hooi Khoo, David J. Vocadlo, Esther M. Verheyen

Proc Natl Acad Sci U S A. 2020 Jan 28; 117(4): 2004–2013. Published online 2020 Jan 13. doi: 10.1073/pnas.1912894117

PMCID:: PMC6994980

Abstract Article PDF–2.1M

Select item 65151197.

Drosophila Homeodomain-Interacting Protein Kinase (Hipk) Phosphorylates the Homeodomain Proteins Homeobrain, Empty Spiracles, and Muscle Segment Homeobox

Eva Louise Steinmetz, Denise Nicole Dewald, Nadine Luxem, Uwe Walldorf

Int J Mol Sci. 2019 Apr; 20(8): 1931. Published online 2019 Apr 19. doi: 10.3390/ijms20081931

PMCID:: PMC6515119

Abstract Article PDF–9.0M

Select item 105797988.

The AMPK-like protein kinases Sik2 and Sik3 interact with Hipk and induce synergistic tumorigenesis in a Drosophila cancer model

Kewei Yu, Niveditha Ramkumar, Kenneth Kin Lam Wong, Gritta Tettweiler, Esther M. Verheyen

Front Cell Dev Biol. 2023; 11: 1214539. Published online 2023 Oct 3. doi: 10.3389/fcell.2023.1214539

PMCID:: PMC10579798

Abstract Article PDF–4.5M

Select item 70802319.

Homeodomain-interacting protein kinase (Hipk) plays roles in nervous system and muscle structure and function

Simon J. H. Wang, Donald A. R. Sinclair, Hae-Yoon Kim, Stephen D. Kinsey, Byoungjoo Yoo, Claire R. Y. Shih, Kenneth K. L. Wong, Charles Krieger, Nicholas Harden, Esther M. Verheyen

PLoS One. 2020; 15(3): e0221006. Published online 2020 Mar 18. doi: 10.1371/journal.pone.0221006

PMCID:: PMC7080231

Abstract Article PDF–5.3M

Select item 596780710.

Prickle is phosphorylated by Nemo and targeted for degradation to maintain Prickle/Spiny-legs isoform balance during planar cell polarity establishment

Giovanna M. Collu, Andreas Jenny, Konstantin Gaengel, Ivana Mirkovic, Mei-ling Chin, Ursula Weber, Michael J. Smith, Marek Mlodzik

PLoS Genet. 2018 May; 14(5): e1007391. Published online 2018 May 14. doi: 10.1371/journal.pgen.1007391

PMCID:: PMC5967807

Abstract Article PDF–20M

Select item 433373211.

The Hippo Pathway Regulates Homeostatic Growth of Stem Cell Niche Precursors in the Drosophila Ovary

Didem P. Sarikaya, Cassandra G. Extavour

PLoS Genet. 2015 Feb; 11(2): e1004962. Published online 2015 Feb 2. doi: 10.1371/journal.pgen.1004962

PMCID:: PMC4333732

Abstract Article PDF–2.7M

Select item 459436212.

Kicking it up a Notch for the best in show: Scalloped leads Yorkie into the haematopoietic arena

Gabriel B Ferguson, Julian A Martinez-Agosto

Fly (Austin) 2014 Oct; 8(4): 206–217. Published online 2015 Jul 7. doi: 10.1080/19336934.2015.1055427

PMCID:: PMC4594362

Abstract Article PDF–1.3M

Select item 311643713.

Drosophila homeodomain-interacting protein kinase inhibits the Skp1-Cul1-F-box E3 ligase complex to dually promote Wingless and Hedgehog signaling

Sharan Swarup, Esther M. Verheyen

Proc Natl Acad Sci U S A. 2011 Jun 14; 108(24): 9887–9892. Published online 2011 May 31. doi: 10.1073/pnas.1017548108

PMCID:: PMC3116437

Abstract Article PDF–989K

Select item 774666514.

Hyperpolarized mitochondria accumulate in Drosophila Hipk-overexpressing cells to drive tumor-like growth

Kenneth Kin Lam Wong, Jenny Zhe Liao, Claire R. Y. Shih, Nicholas Harden, Esther M. Verheyen

J Cell Sci. 2020 Dec 1; 133(23): jcs250944. Published online 2020 Dec 9. doi: 10.1242/jcs.250944

PMCID:: PMC7746665

Abstract Article

Select item 1099529015.

What can the common fruit fly teach us about stroke?: lessons learned from the hypoxic tolerant Drosophila melanogaster

Princy S. Quadros-Mennella, Kurt M. Lucin, Robin E. White

Front Cell Neurosci. 2024; 18: 1347980. Published online 2024 Mar 22. doi: 10.3389/fncel.2024.1347980

Correction in:: Front Cell Neurosci. 2024; 18: 1422866.

PMCID:: PMC10995290

Abstract Article PDF–1.2M

Select item 581807616.

Homeodomain-interacting protein kinase promotes tumorigenesis and metastatic cell behavior

Jessica A. Blaquiere, Kenneth Kin Lam Wong, Stephen D. Kinsey, Jin Wu, Esther M. Verheyen

Dis Model Mech. 2018 Jan 1; 11(1): dmm031146. doi: 10.1242/dmm.031146

PMCID:: PMC5818076

Abstract Article

Select item 415767017.

Riquiqui and Minibrain, new regulators of the Hippo pathway downstream of Dachsous

Joffrey Degoutin, Claire C. Milton, Eefang Yu, Marla Tipping, Floris Bosveld, Yohanns Bellaiche, Alexey Veraksa, Kieran F. Harvey

Nat Cell Biol. Author manuscript; available in PMC 2014 Sep 8.

Published in final edited form as: Nat Cell Biol. 2013 Oct; 15(10): 1176–1185. Published online 2013 Aug 18. doi: 10.1038/ncb2829

PMCID:: PMC4157670

Abstract Article PDF–876K

Select item 146151918.

Dual-tagging gene trap of novel genes in Drosophila melanogaster.

T Lukacsovich, Z Asztalos, W Awano, K Baba, S Kondo, S Niwa, D Yamamoto

Genetics. 2001 Feb; 157(2): 727–742. doi: 10.1093/genetics/157.2.727

PMCID:: PMC1461519

Summary PDF–659K

Select item 206446419.

A collective form of cell death requires homeodomain interacting protein kinase

Nichole Link, Po Chen, Wan-Jin Lu, Kristi Pogue, Amy Chuong, Miguel Mata, Joshua Checketts, John M. Abrams

J Cell Biol. 2007 Aug 13; 178(4): 567–574. doi: 10.1083/jcb.200702125

PMCID:: PMC2064464

Abstract Article PDF–1.5M

Select item 660684820.

Rare variants in MYH15 modify amyotrophic lateral sclerosis risk

Hyerim Kim, Junghwa Lim, Han Bao, Bin Jiao, Se Min Canon, Michael P Epstein, Keqin Xu, Jie Jiang, Janani Parameswaran, Yingjie Li, Kenneth H Moberg, John E Landers, Christina Fournier, Emily G Allen, Jonathan D Glass, Thomas S Wingo, Peng Jin

Hum Mol Genet. 2019 Jul 15; 28(14): 2309–2318. Published online 2019 Apr 1. doi: 10.1093/hmg/ddz063