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Items: 1 to 20 of 93

1.
Downregulation of IL-8 and IL-10 by the Activation of Ca2+-Activated K+ Channel KCa3.1 in THP-1-Derived M2 Macrophages
Susumu Ohya, Miki Matsui, Junko Kajikuri, Hiroaki Kito, Kyoko Endo
Int J Mol Sci. 2022 Aug; 23(15): 8603. Published online 2022 Aug 3. doi: 10.3390/ijms23158603
PMCID:
PMC9368915
AbstractArticlePDF–6.0M
2.
KCNN4 Promotes the Stemness Potentials of Liver Cancer Stem Cells by Enhancing Glucose Metabolism
Jing Fan, Ruofei Tian, Xiangmin Yang, Hao Wang, Ying Shi, Xinyu Fan, Jiajia Zhang, Yatong Chen, Kun Zhang, Zhinan Chen, Ling Li
Int J Mol Sci. 2022 Jul; 23(13): 6958. Published online 2022 Jun 23. doi: 10.3390/ijms23136958
PMCID:
PMC9266406
AbstractArticlePDF–19M
3.
KCa3.1-dependent uptake of the cytotoxic DNA-binding dye Hoechst 33258 into cancerous but not healthy cervical cells
Maurish Bukhari, Han Deng, Darren Sipes, Marisa Ruane-Foster, Kayla Purdy, Craig D. Woodworth, Shantanu Sur, Damien S.K. Samways
J Biol Chem. 2021 Jan-Jun; 296: 100084. Published online 2020 Nov 23. doi: 10.1074/jbc.RA120.013997
PMCID:
PMC7948979
AbstractArticlePDF–2.8M
4.
ATP-evoked intracellular Ca2+ transients shape the ionic permeability of human microglia from epileptic temporal cortex
Nicole Piera Palomba, Katiuscia Martinello, Germana Cocozza, Sara Casciato, Addolorata Mascia, Giancarlo Di Gennaro, Roberta Morace, Vincenzo Esposito, Heike Wulff, Cristina Limatola, Sergio Fucile
J Neuroinflammation. 2021; 18: 44. Published online 2021 Feb 15. doi: 10.1186/s12974-021-02096-0
PMCID:
PMC7883449
AbstractArticlePDF–1.0M
5.
KCNN4 is a diagnostic and prognostic biomarker that promotes papillary thyroid cancer progression
Jialiang Wen, Bangyi Lin, Lizhi Lin, Yizuo Chen, Ouchen Wang
Aging (Albany NY) 2020 Aug 31; 12(16): 16437–16456. Published online 2020 Aug 28. doi: 10.18632/aging.103710
PMCID:
PMC7485723
AbstractArticlePDF–2.5M
6.
Ca2+-dependent endoplasmic reticulum stress correlation with astrogliosis involves upregulation of KCa3.1 and inhibition of AKT/mTOR signaling
Zhihua Yu, Fangfang Dou, Yanxia Wang, Lina Hou, Hongzhuan Chen
J Neuroinflammation. 2018; 15: 316. Published online 2018 Nov 15. doi: 10.1186/s12974-018-1351-x
PMCID:
PMC6236981
AbstractArticlePDF–13M
7.
Differential DNA methylation of potassium channel KCa3.1 and immune signalling pathways is associated with infant immune responses following BCG vaccination
Mateusz Hasso-Agopsowicz, Thomas J. Scriba, Willem A. Hanekom, Hazel M. Dockrell, Steven G. Smith
Sci Rep. 2018; 8: 13086. Published online 2018 Aug 30. doi: 10.1038/s41598-018-31537-9
PMCID:
PMC6117309
AbstractArticlePDF–3.3M
8.
Crystal structure of the C-terminal four-helix bundle of the potassium channel KCa3.1
Tianyang Ji, Senena Corbalán-García, Stevan R. Hubbard
PLoS One. 2018; 13(6): e0199942. Published online 2018 Jun 28. doi: 10.1371/journal.pone.0199942
Correction in:
PLoS One. 2018; 13(10): e0205540.
PMCID:
PMC6023178
AbstractArticlePDF–2.1M
9.
A defect in KCa3.1 channel activity limits the ability of CD8+ T cells from cancer patients to infiltrate an adenosine-rich microenvironment
Ameet A. Chimote, Andras Balajthy, Michael J. Arnold, Hannah S. Newton, Peter Hajdu, Julianne Qualtieri, Trisha Wise-Draper, Laura Conforti
Sci Signal. Author manuscript; available in PMC 2018 Oct 24.
Published in final edited form as: Sci Signal. 2018 Apr 24; 11(527): eaaq1616. Published online 2018 Apr 24. doi: 10.1126/scisignal.aaq1616
PMCID:
PMC6006512
AbstractArticlePDF–1.7M
10.
SK4 K+ channels are therapeutic targets for the treatment of cardiac arrhythmias
Shiraz Haron‐Khun, David Weisbrod, Hanna Bueno, Dor Yadin, Joachim Behar, Asher Peretz, Ofer Binah, Edith Hochhauser, Michael Eldar, Yael Yaniv, Michael Arad, Bernard Attali
EMBO Mol Med. 2017 Apr; 9(4): 415–429. Published online 2017 Feb 20. doi: 10.15252/emmm.201606937
PMCID:
PMC5376763
AbstractArticlePDF–2.4M
11.
Intermediate-Conductance-Ca2-Activated K Channel Intermediate-Conductance Calcium-Activated Potassium Channel (IKCa1) is Upregulated and Promotes Cell Proliferation in Cervical Cancer
Ling Liu, Ping Zhan, Dan Nie, Lingye Fan, Hairui Lin, Lanyang Gao, Xiguang Mao
Med Sci Monit Basic Res. 2017; 23: 45–57. Published online 2017 Mar 10. doi: 10.12659/MSMBR.901462
PMCID:
PMC5358865
AbstractArticlePDF–1.3M
12.
Inhibition of SK4 Potassium Channels Suppresses Cell Proliferation, Migration and the Epithelial-Mesenchymal Transition in Triple-Negative Breast Cancer Cells
Panshi Zhang, Xiaowei Yang, Qian Yin, Jilin Yi, Wenzhuang Shen, Lu Zhao, Zhi Zhu, Jinwen Liu
PLoS One. 2016; 11(4): e0154471. Published online 2016 Apr 28. doi: 10.1371/journal.pone.0154471
PMCID:
PMC4849628
AbstractArticlePDF–7.4M
13.
KCa3.1 K+ Channel Expression and Function in Human Bronchial Epithelial Cells
Greer K. Arthur, S. Mark Duffy, Katy M. Roach, Rob A. Hirst, Aarti Shikotra, Erol A. Gaillard, Peter Bradding
PLoS One. 2015; 10(12): e0145259. Published online 2015 Dec 21. doi: 10.1371/journal.pone.0145259
PMCID:
PMC4687003
AbstractArticlePDF–874K
14.
KCa3.1-Dependent Hyperpolarization Enhances Intracellular Ca2+ Signaling Induced by fMLF in Differentiated U937 Cells
Antonello Penna, Andrés Stutzin
PLoS One. 2015; 10(9): e0139243. Published online 2015 Sep 29. doi: 10.1371/journal.pone.0139243
PMCID:
PMC4587941
AbstractArticlePDF–666K
15.
Mutations in the Gardos channel (KCNN4) are associated with hereditary xerocytosis
Edyta Glogowska, Kimberly Lezon-Geyda, Yelena Maksimova, Vincent P. Schulz, Patrick G. Gallagher
Blood. 2015 Sep 10; 126(11): 1281–1284. Prepublished online 2015 Jul 21. doi: 10.1182/blood-2015-07-657957
PMCID:
PMC4566808
AbstractArticle
16.
Selective inhibition of KCa3.1 channels mediates adenosine regulation of the motility of human T cells
Ameet A. Chimote, Peter Hajdu, Vladimir Kucher, Nina Boiko, Zerrin Kuras, Orsolya Szilagyi, Yeo-Heung Yun, Laura Conforti
J Immunol. Author manuscript; available in PMC 2015 Apr 30.
Published in final edited form as: J Immunol. 2013 Dec 15; 191(12): 6273–6280. Published online 2013 Nov 13. doi: 10.4049/jimmunol.1300702
PMCID:
PMC4415878
AbstractArticlePDF–1.1M
17.
High Expression of KCa3.1 in Patients with Clear Cell Renal Carcinoma Predicts High Metastatic Risk and Poor Survival
Maj Rabjerg, Aida Oliván-Viguera, Lars Koch Hansen, Line Jensen, Linda Sevelsted-Møller, Steen Walter, Boye L. Jensen, Niels Marcussen, Ralf Köhler
PLoS One. 2015; 10(4): e0122992. Published online 2015 Apr 7. doi: 10.1371/journal.pone.0122992
PMCID:
PMC4388734
AbstractArticlePDF–8.1M
18.
A pro-invasive role for the Ca2+-activated K+ channel KCa3.1 in malignant glioma
Kathryn L. Turner, Avinash Honasoge, Stephanie M. Robert, Michael M. McFerrin, Harald Sontheimer
Glia. Author manuscript; available in PMC 2015 Jun 1.
Published in final edited form as: Glia. 2014 Jun; 62(6): 971–981. Published online 2014 Mar 2. doi: 10.1002/glia.22655
PMCID:
PMC4006152
AbstractArticlePDF–1.4M
19.
Aromatic–aromatic interactions between residues in KCa3.1 pore helix and S5 transmembrane segment control the channel gating process
Line Garneau, Hélène Klein, Marie-France Lavoie, Emmanuelle Brochiero, Lucie Parent, Rémy Sauvé
J Gen Physiol. 2014 Feb; 143(2): 289–307. doi: 10.1085/jgp.201311097
PMCID:
PMC4001770
AbstractArticlePDF–2.8M
20.
The K+ Channel KCa3.1 as a Novel Target for Idiopathic Pulmonary Fibrosis
Katy Morgan Roach, Stephen Mark Duffy, William Coward, Carol Feghali-Bostwick, Heike Wulff, Peter Bradding
PLoS One. 2013; 8(12): e85244. Published online 2013 Dec 31. doi: 10.1371/journal.pone.0085244
Correction in:
PLoS One. 2014; 9(1): 10.1371/annotation/790e86f8-3506-49d6-b7d0-7dbbc580d808.
PMCID:
PMC3877378
AbstractArticlePDF–2.6M

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