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Select item 42163371.

Strategies for gene disruption in Drosophila

Shih-Ching Lin, Yu-Yun Chang, Chih-Chiang Chan

Cell Biosci. 2014; 4: 63. Published online 2014 Oct 14. doi: 10.1186/2045-3701-4-63

PMCID:: PMC4216337

Abstract Article PDF–963K

Select item 26049402.

Efficient gene targeting in Drosophila by direct embryo injection with zinc-finger nucleases

Kelly J. Beumer, Jonathan K. Trautman, Ana Bozas, Ji-Long Liu, Jared Rutter, Joseph G. Gall, Dana Carroll

Proc Natl Acad Sci U S A. 2008 Dec 16; 105(50): 19821–19826. Published online 2008 Dec 8. doi: 10.1073/pnas.0810475105

PMCID:: PMC2604940

Abstract Article PDF–375K

Select item 22232913.

The Drosophila Basic Helix-Loop-Helix Protein DIMMED Directly Activates PHM, a Gene Encoding a Neuropeptide-Amidating Enzyme

Dongkook Park, Orie T. Shafer, Stacie P. Shepherd, Hyunsuk Suh, Jennifer S. Trigg, Paul H. Taghert

Mol Cell Biol. 2008 Jan; 28(1): 410–421. Published online 2007 Oct 29. doi: 10.1128/MCB.01104-07

PMCID:: PMC2223291

Abstract Article PDF–1.1M

Select item 1232364.

The anaphase promoting complex/cyclosome is required during development for modified cell cycles

Helena Kashevsky, Julie A. Wallace, Bruce H. Reed, Cary Lai, Aki Hayashi-Hagihara, Terry L. Orr-Weaver

Proc Natl Acad Sci U S A. 2002 Aug 20; 99(17): 11217–11222. Published online 2002 Aug 8. doi: 10.1073/pnas.172391099

PMCID:: PMC123236

Abstract Article PDF–635K

Select item 18905035.

A genome-wide RNA interference screen identifies putative chromatin regulators essential for E2F repression

Jianrong Lu, Marie-Laure Ruhf, Norbert Perrimon, Philip Leder

Proc Natl Acad Sci U S A. 2007 May 29; 104(22): 9381–9386. Published online 2007 May 17. doi: 10.1073/pnas.0610279104

PMCID:: PMC1890503

Abstract Article PDF–1.3M

Select item 62154176.

Chromosomal instability causes sensitivity to protein folding stress and ATP depletion

Mahwish Khan, Zeeshan Shaukat, Robert Saint, Stephen L. Gregory

Biol Open. 2018 Oct 15; 7(10): bio038000. Published online 2018 Oct 15. doi: 10.1242/bio.038000

PMCID:: PMC6215417

Abstract Article PDF–7.0M

Select item 34718127.

A Screen for Selective Killing of Cells with Chromosomal Instability Induced by a Spindle Checkpoint Defect

Zeeshan Shaukat, Heidi W. S. Wong, Shannon Nicolson, Robert B. Saint, Stephen L. Gregory

PLoS One. 2012; 7(10): e47447. Published online 2012 Oct 15. doi: 10.1371/journal.pone.0047447

PMCID:: PMC3471812

Abstract Article PDF–1.4M

Select item 28637018.

Drosophila RB Proteins Repress Differentiation-Specific Genes via Two Different Mechanisms

Hangnoh Lee, Katsuhito Ohno, Yekaterina Voskoboynik, Linda Ragusano, Anna Martinez, Dessislava K. Dimova

Mol Cell Biol. 2010 May; 30(10): 2563–2577. Published online 2010 Feb 22. doi: 10.1128/MCB.01075-09

PMCID:: PMC2863701

Abstract Article PDF–2.6M

Select item 5346539.

Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex

Peter W. Lewis, Eileen L. Beall, Tracey C. Fleischer, Daphne Georlette, Andrew J. Link, Michael R. Botchan

Genes Dev. 2004 Dec 1; 18(23): 2929–2940. doi: 10.1101/gad.1255204

PMCID:: PMC534653

Abstract Article PDF–448K

Select item 582520810.

A kinase-dependent feedforward loop affects CREBB stability and long term memory formation

Pei-Tseng Lee, Guang Lin, Wen-Wen Lin, Fengqiu Diao, Benjamin H White, Hugo J Bellen

eLife. 2018; 7: e33007. Published online 2018 Feb 23. doi: 10.7554/eLife.33007

PMCID:: PMC5825208

Abstract Article PDF–4.0M

Select item 51789511.

p55, the Drosophila Ortholog of RbAp46/RbAp48, Is Required for the Repression of dE2F2/RBF-Regulated Genes

Barbie Taylor-Harding, Ulrich K. Binné, Michael Korenjak, Alexander Brehm, Nicholas J. Dyson

Mol Cell Biol. 2004 Oct; 24(20): 9124–9136. doi: 10.1128/MCB.24.20.9124-9136.2004

PMCID:: PMC517895

Abstract Article PDF–681K

Select item 654822712.

Cross-species genetic screens to identify kinase targets for APP reduction in Alzheimer's disease

Claudia H Huichalaf, Ismael Al-Ramahi, Kyung-Won Park, Stacy D Grunke, Nan Lu, Maria de Haro, Karla El-Zein, Tatiana Gallego-Flores, Alma M Perez, Sung Yun Jung, Juan Botas, Huda Y Zoghbi, Joanna L Jankowsky

Hum Mol Genet. 2019 Jun 15; 28(12): 2014–2029. Published online 2019 Feb 12. doi: 10.1093/hmg/ddz034

PMCID:: PMC6548227

Abstract Article PDF–24M

Select item 802294613.

An RNAi screen of the kinome in epithelial follicle cells of the Drosophila melanogaster ovary reveals genes required for proper germline death and clearance

Diane P V Lebo, Alice Chirn, Jeffrey D Taylor, Andre Levan, Valentina Doerre Torres, Emily Agreda, Sandy B Serizier, Allison K Lord, Victoria K Jenkins, Kimberly McCall

G3 (Bethesda) 2021 Feb; 11(2): jkaa066. Published online 2021 Mar 6. doi: 10.1093/g3journal/jkaa066

PMCID:: PMC8022946

Abstract Article PDF–1.3M

Select item 612381014.

Circulating glucose levels inversely correlate with Drosophila larval feeding through insulin signaling and SLC5A11

Rupali Ugrankar, Pano Theodoropoulos, Fatih Akdemir, W. Mike Henne, Jonathan M. Graff

Commun Biol. 2018; 1: 110. Published online 2018 Aug 13. doi: 10.1038/s42003-018-0109-4

PMCID:: PMC6123810

Abstract Article PDF–3.4M

Select item 204919115.

Genomic profiling and expression studies reveal both positive and negative activities for the Drosophila Myb–MuvB/dREAM complex in proliferating cells

Daphne Georlette, Soyeon Ahn, David M. MacAlpine, Evelyn Cheung, Peter W. Lewis, Eileen L. Beall, Stephen P. Bell, Terry Speed, J. Robert Manak, Michael R. Botchan

Genes Dev. 2007 Nov 15; 21(22): 2880–2896. doi: 10.1101/gad.1600107

PMCID:: PMC2049191

Abstract Article PDF–1.4M

Select item 19646716.

Cell cycle-dependent and cell cycle-independent control of transcription by the Drosophila E2F/RB pathway

Dessislava K. Dimova, Olivier Stevaux, Maxim V. Frolov, Nicholas J. Dyson

Genes Dev. 2003 Sep 15; 17(18): 2308–2320. doi: 10.1101/gad.1116703

PMCID:: PMC196467

Abstract Article PDF–496K

Select item 445513017.

Drosophila glucome screening identifies Ck1alpha as a regulator of mammalian glucose metabolism

Rupali Ugrankar, Eric Berglund, Fatih Akdemir, Christopher Tran, Min Soo Kim, Jungsik Noh, Rebekka Schneider, Benjamin Ebert, Jonathan M. Graff

Nat Commun. 2015; 6: 7102. Published online 2015 May 21. doi: 10.1038/ncomms8102

PMCID:: PMC4455130

Abstract Article PDF–696K

Select item 593136918.

A Whole Animal Platform to Advance A Clinical Kinase Inhibitor Into New Disease Space

Masahiro Sonoshita, Alex P. Scopton, Peter M-U. Ung, Matthew A. Murray, Lisa Silber, Andres Y. Maldonado, Alexander Real, Avner Schlessinger, Ross L. Cagan, Arvin C. Dar

Nat Chem Biol. Author manuscript; available in PMC 2018 Jul 22.

Published in final edited form as: Nat Chem Biol. 2018 Mar; 14(3): 291–298. Published online 2018 Jan 22. doi: 10.1038/nchembio.2556

PMCID:: PMC5931369

Abstract Article PDF–2.9M

Select item 533337219.

Nociceptor-enriched genes required for normal thermal nociception

Ken Honjo, Stephanie E. Mauthner, Yu Wang, J.H. Pate Skene, W. Daniel Tracey, Jr.

Cell Rep. Author manuscript; available in PMC 2017 Mar 2.

Published in final edited form as: Cell Rep. 2016 Jul 12; 16(2): 295–303. Published online 2016 Jun 23. doi: 10.1016/j.celrep.2016.06.003

PMCID:: PMC5333372

Abstract Article PDF–1.6M

Select item 846882720.

Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders

Stefano Sechi, Angela Karimpour-Ghahnavieh, Anna Frappaolo, Laura Di Francesco, Roberto Piergentili, Eugenia Schininà, Pier Paolo D’Avino, Maria Grazia Giansanti

Cells. 2021 Sep; 10(9): 2336. Published online 2021 Sep 6. doi: 10.3390/cells10092336